An evaluation of the genotoxic and cytotoxic effects of the anti-obesity drugs sibutramine and fenproporex

Human and Experimental Toxicology

Volumn 29, Issue 3, 2010, Pages 187-197

  Da Silva, Cristiano José ^a   Dos Santos, José Ernesto ^a   Satie Takahashi, Catarina ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Anti obesity; Cytotoxic; Fenproporex; Genotoxic; Sibutramine

Indexed keywords

DOXORUBICIN; FENPROPOREX; SIBUTRAMINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BODY WEIGHT; BONE MARROW; COMET ASSAY; CONTROLLED STUDY; CYTOTOXICITY; DOUBLE STRANDED DNA BREAK; DRUG MECHANISM; DRUG MEGADOSE; ERYTHROCYTE; GENOTOXICITY; MALE; MICRONUCLEUS TEST; MOUSE; NONHUMAN; PRIORITY JOURNAL; SINGLE STRANDED DNA BREAK; SWISS WEBSTER MOUSE;

AMPHETAMINES; ANIMALS; ANTI-OBESITY AGENTS; BONE MARROW CELLS; COMET ASSAY; CYCLOBUTANES; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; INJECTIONS, INTRAPERITONEAL; LEUKOCYTES, MONONUCLEAR; MALE; MICE; MICRONUCLEI, CHROMOSOME-DEFECTIVE; RISK ASSESSMENT;

ANIMALIA; MUS;

EID: 77749282863     PISSN: 09603271     EISSN: 14770903     Source Type: Journal    
DOI: 10.1177/0960327109358732     Document Type: Article

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