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Volumn 5, Issue JUN, 2014, Pages

Is homologous recombination really an error-free process?

Author keywords

DNA double strand break repair; Genetic instability; Genetic variability; Homologous recombination; Mutagenesis; Replication stress

Indexed keywords

APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 1; BRCA1 PROTEIN; BRCA2 PROTEIN; PROTEIN BCL 2; RAD51 PROTEIN;

EID: 84906245025     PISSN: None     EISSN: 16648021     Source Type: Journal    
DOI: 10.3389/fgene.2014.00175     Document Type: Review
Times cited : (94)

References (168)
  • 1
    • 33645359197 scopus 로고    scopus 로고
    • Mutagenesis and the three R's in yeast
    • doi: 10.1016/j.dnarep.2005.11.006
    • Abdulovic, A., Kim, N., and Jinks-Robertson, S. (2006). Mutagenesis and the three R's in yeast. DNA Repair (Amst.) 5, 409-421. doi: 10.1016/j.dnarep.2005.11.006
    • (2006) DNA Repair (Amst.) , vol.5 , pp. 409-421
    • Abdulovic, A.1    Kim, N.2    Jinks-Robertson, S.3
  • 2
    • 84887595526 scopus 로고    scopus 로고
    • Causes of genome instability
    • doi: 10.1146/annurev-genet-111212-133232
    • Aguilera, A., and Garcia-Muse, T. (2013). Causes of genome instability. Annu. Rev. Genet . 47, 1-32. doi: 10.1146/annurev-genet-111212-133232
    • (2013) Annu. Rev. Genet. , vol.47 , pp. 1-32
    • Aguilera, A.1    Garcia-Muse, T.2
  • 3
    • 39449096135 scopus 로고    scopus 로고
    • Genome instability: a mechanistic view of its causes and consequences
    • doi: 10.1038/nrg2268
    • Aguilera, A., and Gomez-Gonzalez, B. (2008). Genome instability: a mechanistic view of its causes and consequences. Nat. Rev. Genet . 9, 204-217. doi: 10.1038/nrg2268
    • (2008) Nat. Rev. Genet. , vol.9 , pp. 204-217
    • Aguilera, A.1    Gomez-Gonzalez, B.2
  • 5
    • 0007383587 scopus 로고
    • Mutation in the CYP21B gene (Ile-172-Asn) causes steroid 21- hydroxylase deficiency
    • doi: 10.1073/pnas.85.5.1600
    • Amor, M., Parker, K. L., Globerman, H., New, M. I., and White, P. C. (1988). Mutation in the CYP21B gene (Ile-172-Asn) causes steroid 21- hydroxylase deficiency. Proc. Natl. Acad. Sci. U.S.A . 85, 1600-1604. doi: 10.1073/pnas.85.5.1600
    • (1988) Proc. Natl. Acad. Sci. U.S.A. , vol.85 , pp. 1600-1604
    • Amor, M.1    Parker, K.L.2    Globerman, H.3    New, M.I.4    White, P.C.5
  • 6
    • 0003016687 scopus 로고
    • Concerted evolution of multigene families
    • Evolution of Genes and Proteins , eds R. K. Koehn and M. Nei (Sunderland, MA: Sinauer Associates)
    • Arnheim, N. (1983). "Concerted evolution of multigene families," in Evolution of Genes and Proteins , eds R. K. Koehn and M. Nei (Sunderland, MA: Sinauer Associates), 38-61.
    • (1983) , pp. 38-61
    • Arnheim, N.1
  • 7
    • 40749107055 scopus 로고    scopus 로고
    • Minichromosome maintenance proteins interact with checkpoint and recombination proteins to promote s-phase genome stability
    • doi: 10.1128/MCB.01717-07
    • Bailis, J. M., Luche, D. D., Hunter, T., and Forsburg, S. L. (2008). Minichromosome maintenance proteins interact with checkpoint and recombination proteins to promote s-phase genome stability. Mol. Cell. Biol . 28, 1724-1738. doi: 10.1128/MCB.01717-07
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 1724-1738
    • Bailis, J.M.1    Luche, D.D.2    Hunter, T.3    Forsburg, S.L.4
  • 8
    • 53549122238 scopus 로고    scopus 로고
    • RTEL1 maintains genomic stability by suppressing homologous recombination
    • doi: 10.1016/j.cell.2008.08.016
    • Barber, L. J., Youds, J. L., Ward, J. D., McIlwraith, M. J., O'Neil, N. J., Petalcorin, M. I., et al. (2008). RTEL1 maintains genomic stability by suppressing homologous recombination. Cell 135, 261-271. doi: 10.1016/j.cell.2008.08.016
    • (2008) Cell , vol.135 , pp. 261-271
    • Barber, L.J.1    Youds, J.L.2    Ward, J.D.3    McIlwraith, M.J.4    O'Neil, N.J.5    Petalcorin, M.I.6
  • 9
    • 17244367849 scopus 로고    scopus 로고
    • DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
    • doi: 10.1038/nature03482
    • Bartkova, J., Horejsi, Z., Koed, K., Kramer, A., Tort, F., Zieger, K., et al. (2005). DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis. Nature 434, 864-870. doi: 10.1038/nature03482
    • (2005) Nature , vol.434 , pp. 864-870
    • Bartkova, J.1    Horejsi, Z.2    Koed, K.3    Kramer, A.4    Tort, F.5    Zieger, K.6
  • 10
    • 33845235459 scopus 로고    scopus 로고
    • Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
    • doi: 10.1038/nature05268
    • Bartkova, J., Rezaei, N., Liontos, M., Karakaidos, P., Kletsas, D., Issaeva, N., et al. (2006). Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints. Nature 444, 633-637. doi: 10.1038/nature05268
    • (2006) Nature , vol.444 , pp. 633-637
    • Bartkova, J.1    Rezaei, N.2    Liontos, M.3    Karakaidos, P.4    Kletsas, D.5    Issaeva, N.6
  • 11
    • 79951497419 scopus 로고    scopus 로고
    • The genomic complexity of primary human prostate cancer
    • doi: 10.1038/nature09744
    • Berger, M. F., Lawrence, M. S., Demichelis, F., Drier, Y., Cibulskis, K., Sivachenko, A. Y., et al. (2011). The genomic complexity of primary human prostate cancer. Nature 470, 214-220. doi: 10.1038/nature09744
    • (2011) Nature , vol.470 , pp. 214-220
    • Berger, M.F.1    Lawrence, M.S.2    Demichelis, F.3    Drier, Y.4    Cibulskis, K.5    Sivachenko, A.Y.6
  • 12
    • 78149434190 scopus 로고    scopus 로고
    • The RecQ DNA helicases in DNA repair
    • doi: 10.1146/annurev-genet-102209-163602
    • Bernstein, K. A., Gangloff, S., and Rothstein, R. (2010). The RecQ DNA helicases in DNA repair. Annu. Rev. Genet . 44, 393-417. doi: 10.1146/annurev-genet-102209-163602
    • (2010) Annu. Rev. Genet. , vol.44 , pp. 393-417
    • Bernstein, K.A.1    Gangloff, S.2    Rothstein, R.3
  • 13
    • 0345304254 scopus 로고    scopus 로고
    • Overexpression of mammalian Rad51 does not stimulate tumorigenesis while a dominant-negative Rad51 affects centrosome fragmentation, ploidy and stimulates tumorigenesis, in p53-defective CHO cells
    • doi: 10.1038/sj.onc.1206998
    • Bertrand, P., Lambert, S., Joubert, C., and Lopez, B. S. (2003). Overexpression of mammalian Rad51 does not stimulate tumorigenesis while a dominant-negative Rad51 affects centrosome fragmentation, ploidy and stimulates tumorigenesis, in p53-defective CHO cells. Oncogene 22, 7587-7592. doi: 10.1038/sj.onc.1206998
    • (2003) Oncogene , vol.22 , pp. 7587-7592
    • Bertrand, P.1    Lambert, S.2    Joubert, C.3    Lopez, B.S.4
  • 14
    • 2442477786 scopus 로고    scopus 로고
    • p53's double life: transactivation-independent repression of homologous recombination
    • doi: 10.1016/j.tig.2004.04.003
    • Bertrand, P., Saintigny, Y., and Lopez, B. S. (2004). p53's double life: transactivation-independent repression of homologous recombination. Trends Genet . 20, 235-243. doi: 10.1016/j.tig.2004.04.003
    • (2004) Trends Genet. , vol.20 , pp. 235-243
    • Bertrand, P.1    Saintigny, Y.2    Lopez, B.S.3
  • 15
    • 84896717088 scopus 로고    scopus 로고
    • Is non-homologous end-joining really an inherently error-prone process?
    • doi: 10.1371/journal.pgen.1004086
    • Betermier, M., Bertrand, P., and Lopez, B. S. (2014). Is non-homologous end-joining really an inherently error-prone process? PLoS Genet . 10:e1004086. doi: 10.1371/journal.pgen.1004086
    • (2014) PLoS Genet , vol.10
    • Betermier, M.1    Bertrand, P.2    Lopez, B.S.3
  • 16
    • 0031737723 scopus 로고    scopus 로고
    • Chromosome break-induced DNA replication leads to nonreciprocal translocations and telomere capture.
    • Bosco, G., and Haber, J. E. (1998). Chromosome break-induced DNA replication leads to nonreciprocal translocations and telomere capture. Genetics 150, 1037-1047.
    • (1998) Genetics , vol.150 , pp. 1037-1047
    • Bosco, G.1    Haber, J.E.2
  • 17
    • 77649165394 scopus 로고    scopus 로고
    • Maintaining genome stability at the replication fork
    • doi: 10.1038/nrm2852
    • Branzei, D., and Foiani, M. (2010). Maintaining genome stability at the replication fork. Nat. Rev. Mol. Cell Biol . 11, 208-219. doi: 10.1038/nrm2852
    • (2010) Nat. Rev. Mol. Cell Biol. , vol.11 , pp. 208-219
    • Branzei, D.1    Foiani, M.2
  • 18
    • 34248631955 scopus 로고    scopus 로고
    • Playing hide and seek with mammalian meiotic crossover hotspots
    • doi: 10.1016/j.tig.2007.03.014
    • Buard, J., and de Massy, B. (2007). Playing hide and seek with mammalian meiotic crossover hotspots. Trends Genet . 23, 301-309. doi: 10.1016/j.tig.2007.03.014
    • (2007) Trends Genet. , vol.23 , pp. 301-309
    • Buard, J.1    de Massy, B.2
  • 19
    • 84874188583 scopus 로고    scopus 로고
    • APOBEC3B is an enzymatic source of mutation in breast cancer
    • doi: 10.1038/nature11881
    • Burns, M. B., Lackey, L., Carpenter, M. A., Rathore, A., Land, A. M., Leonard, B., et al. (2013). APOBEC3B is an enzymatic source of mutation in breast cancer. Nature 494, 366-370. doi: 10.1038/nature11881
    • (2013) Nature , vol.494 , pp. 366-370
    • Burns, M.B.1    Lackey, L.2    Carpenter, M.A.3    Rathore, A.4    Land, A.M.5    Leonard, B.6
  • 20
    • 0026094779 scopus 로고
    • Adaptive reversion of a frameshift mutation in Escherichia coli.
    • Cairns, J., and Foster, P. L. (1991) Adaptive reversion of a frameshift mutation in Escherichia coli. Genetics 128, 695-701.
    • (1991) Genetics , vol.128 , pp. 695-701
    • Cairns, J.1    Foster, P.L.2
  • 21
    • 84872008477 scopus 로고    scopus 로고
    • Base damage within single-strand DNA underlies in vivo hypermutability induced by a ubiquitous environmental agent.
    • doi: 10.1371/journal.pgen.1003149
    • Chan, K., Sterling, J. F., Roberts, S. A., Bhagwat, A. S., Resnick, M. A., and Gordenin, D. A. (2012). Base damage within single-strand DNA underlies in vivo hypermutability induced by a ubiquitous environmental agent. PLoS Genet . 8:e1003149. doi: 10.1371/journal.pgen.1003149
    • (2012) PLoS Genet , vol.8
    • Chan, K.1    Sterling, J.F.2    Roberts, S.A.3    Bhagwat, A.S.4    Resnick, M.A.5    Gordenin, D.A.6
  • 22
    • 67349227137 scopus 로고    scopus 로고
    • Replication stress induces sister-chromatid bridging at fragile site loci in mitosis
    • doi: 10.1038/ncb1882
    • Chan, K. L., Palmai-Pallag, T., Ying, S., and Hickson, I. D. (2009). Replication stress induces sister-chromatid bridging at fragile site loci in mitosis. Nat. Cell Biol . 11, 753-760. doi: 10.1038/ncb1882
    • (2009) Nat. Cell Biol. , vol.11 , pp. 753-760
    • Chan, K.L.1    Palmai-Pallag, T.2    Ying, S.3    Hickson, I.D.4
  • 23
    • 34548743476 scopus 로고    scopus 로고
    • Gene conversion: mechanisms, evolution and human disease
    • doi: 10.1038/nrg2193
    • Chen, J. M., Cooper, D. N., Chuzhanova, N., Ferec, C., and Patrinos, G. P. (2007). Gene conversion: mechanisms, evolution and human disease. Nat. Rev. Genet . 8, 762-775. doi: 10.1038/nrg2193
    • (2007) Nat. Rev. Genet. , vol.8 , pp. 762-775
    • Chen, J.M.1    Cooper, D.N.2    Chuzhanova, N.3    Ferec, C.4    Patrinos, G.P.5
  • 24
    • 69249209608 scopus 로고    scopus 로고
    • RecQ helicases: multifunctional genome caretakers
    • doi: 10.1038/nrc2682
    • Chu, W. K., and Hickson, I. D. (2009). RecQ helicases: multifunctional genome caretakers. Nat. Rev. Cancer 9, 644-654. doi: 10.1038/nrc2682
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 644-654
    • Chu, W.K.1    Hickson, I.D.2
  • 25
    • 84892743776 scopus 로고    scopus 로고
    • Break-induced replication repair of damaged forks induces genomic duplications in human cells
    • doi: 10.1126/science.1243211
    • Costantino, L., Sotiriou, S. K., Rantala, J. K., Magin, S., Mladenov, E., Helleday, T., et al. (2014). Break-induced replication repair of damaged forks induces genomic duplications in human cells. Science 343, 88-91. doi: 10.1126/science.1243211
    • (2014) Science , vol.343 , pp. 88-91
    • Costantino, L.1    Sotiriou, S.K.2    Rantala, J.K.3    Magin, S.4    Mladenov, E.5    Helleday, T.6
  • 26
    • 33646171879 scopus 로고    scopus 로고
    • A mutation in Tac1p, a transcription factor regulating CDR1 and CDR2, is coupled with loss of heterozygosity at chromosome 5 to mediate antifungal resistance in Candida albicans
    • doi: 10.1534/genetics.105.054767
    • Coste, A., Turner, V., Ischer, F., Morschhauser, J., Forche, A., Selmecki, A., et al. (2006). A mutation in Tac1p, a transcription factor regulating CDR1 and CDR2, is coupled with loss of heterozygosity at chromosome 5 to mediate antifungal resistance in Candida albicans. Genetics 172, 2139-2156. doi: 10.1534/genetics.105.054767
    • (2006) Genetics , vol.172 , pp. 2139-2156
    • Coste, A.1    Turner, V.2    Ischer, F.3    Morschhauser, J.4    Forche, A.5    Selmecki, A.6
  • 27
    • 85016350382 scopus 로고    scopus 로고
    • Homologous Recombination as a Replication Fork Escort: Fork-Protection and Recovery
    • doi: 10.3390/biom3010039
    • Costes, A., and Lambert, S. A. (2012). Homologous Recombination as a Replication Fork Escort: Fork-Protection and Recovery. Biomolecules 1, 39-71. doi: 10.3390/biom3010039
    • (2012) Biomolecules , vol.1 , pp. 39-71
    • Costes, A.1    Lambert, S.A.2
  • 28
    • 0348047324 scopus 로고    scopus 로고
    • RecA-dependent recovery of arrested DNA replication forks
    • doi: 10.1146/annurev.genet.37.110801.142616
    • Courcelle, J., and Hanawalt, P. C. (2003). RecA-dependent recovery of arrested DNA replication forks. Annu. Rev. Genet . 37, 611-646. doi: 10.1146/annurev.genet.37.110801.142616
    • (2003) Annu. Rev. Genet. , vol.37 , pp. 611-646
    • Courcelle, J.1    Hanawalt, P.C.2
  • 29
    • 84856424908 scopus 로고    scopus 로고
    • DNA breaks and chromosome pulverization from errors in mitosis
    • doi: 10.1038/nature10802
    • Crasta, K., Ganem, N. J., Dagher, R., Lantermann, A. B., Ivanova, E. V., Pan, Y., et al. (2012). DNA breaks and chromosome pulverization from errors in mitosis. Nature 482, 53-58. doi: 10.1038/nature10802
    • (2012) Nature , vol.482 , pp. 53-58
    • Crasta, K.1    Ganem, N.J.2    Dagher, R.3    Lantermann, A.B.4    Ivanova, E.V.5    Pan, Y.6
  • 30
    • 38949179530 scopus 로고    scopus 로고
    • A homologous recombination defect affects replication-fork progression in mammalian cells
    • doi: 10.1242/jcs.010330
    • Daboussi, F., Courbet, S., Benhamou, S., Kannouche, P., Zdzienicka, M. Z., Debatisse, M., et al. (2008). A homologous recombination defect affects replication-fork progression in mammalian cells. J. Cell Sci . 121, 162-166. doi: 10.1242/jcs.010330
    • (2008) J. Cell Sci. , vol.121 , pp. 162-166
    • Daboussi, F.1    Courbet, S.2    Benhamou, S.3    Kannouche, P.4    Zdzienicka, M.Z.5    Debatisse, M.6
  • 31
    • 19944422423 scopus 로고    scopus 로고
    • Genetic interactions between RAD51 and its paralogues for centrosome fragmentation and ploidy control, independently of the sensitivity to genotoxic stresses
    • doi: 10.1038/sj.onc.1208438
    • Daboussi, F., Thacker, J., and Lopez, B. S. (2005). Genetic interactions between RAD51 and its paralogues for centrosome fragmentation and ploidy control, independently of the sensitivity to genotoxic stresses. Oncogene 24, 3691-3696. doi: 10.1038/sj.onc.1208438
    • (2005) Oncogene , vol.24 , pp. 3691-3696
    • Daboussi, F.1    Thacker, J.2    Lopez, B.S.3
  • 32
    • 79952273242 scopus 로고    scopus 로고
    • Break-induced replication is highly inaccurate.
    • doi: 10.1371/journal.pbio.1000594
    • Deem, A., Keszthelyi, A., Blackgrove, T., Vayl, A., Coffey, B., Mathur, R., et al. (2011). Break-induced replication is highly inaccurate. PLoS Biol . 9:e1000594. doi: 10.1371/journal.pbio.1000594
    • (2011) PLoS Biol , vol.9
    • Deem, A.1    Keszthelyi, A.2    Blackgrove, T.3    Vayl, A.4    Coffey, B.5    Mathur, R.6
  • 33
    • 0037048290 scopus 로고    scopus 로고
    • Roles of BRCA1 in centrosome duplication
    • doi: 10.1038/sj.onc.1205713
    • Deng, C. X. (2002). Roles of BRCA1 in centrosome duplication. Oncogene 21, 6222-6227. doi: 10.1038/sj.onc.1205713
    • (2002) Oncogene , vol.21 , pp. 6222-6227
    • Deng, C.X.1
  • 34
    • 0035313403 scopus 로고    scopus 로고
    • BCR-ABL down-regulates the DNA repair protein DNA-PKcs
    • doi: 10.1182/blood.V97.7.2084
    • Deutsch, E., Dugray, A., AbdulKarim, B., Marangoni, E., Maggiorella, L., Vaganay, S., et al. (2001). BCR-ABL down-regulates the DNA repair protein DNA-PKcs. Blood 97, 2084-2090. doi: 10.1182/blood.V97.7.2084
    • (2001) Blood , vol.97 , pp. 2084-2090
    • Deutsch, E.1    Dugray, A.2    AbdulKarim, B.3    Marangoni, E.4    Maggiorella, L.5    Vaganay, S.6
  • 35
    • 6344285329 scopus 로고    scopus 로고
    • Centrosome amplification induced by DNA damage occurs during a prolonged G2 phase and involves ATM
    • doi: 10.1038/sj.emboj.7600393
    • Dodson, H., Bourke, E., Jeffers, L. J., Vagnarelli, P., Sonoda, E., Takeda, S., et al. (2004). Centrosome amplification induced by DNA damage occurs during a prolonged G2 phase and involves ATM. EMBO J . 23, 3864-3873. doi: 10.1038/sj.emboj.7600393
    • (2004) EMBO J. , vol.23 , pp. 3864-3873
    • Dodson, H.1    Bourke, E.2    Jeffers, L.J.3    Vagnarelli, P.4    Sonoda, E.5    Takeda, S.6
  • 36
    • 0037705461 scopus 로고    scopus 로고
    • Multiple recombination pathways for sister chromatid exchange in Saccharomyces cerevisiae: role of RAD1 and the RAD52 epistasis group genes
    • doi: 10.1093/nar/gkg352
    • Dong, Z., and Fasullo, M. (2003). Multiple recombination pathways for sister chromatid exchange in Saccharomyces cerevisiae: role of RAD1 and the RAD52 epistasis group genes. Nucleic Acids Res . 31, 2576-2585. doi: 10.1093/nar/gkg352
    • (2003) Nucleic Acids Res. , vol.31 , pp. 2576-2585
    • Dong, Z.1    Fasullo, M.2
  • 37
    • 0033996037 scopus 로고    scopus 로고
    • Mouse RAD54 affects DNA double-strand break repair and sister chromatid exchange
    • doi: 10.1128/MCB.20.9.3147-3156.2000
    • Dronkert, M. L., Beverloo, H. B., Johnson, R. D., Hoeijmakers, J. H., Jasin, M., and Kanaar, R. (2000). Mouse RAD54 affects DNA double-strand break repair and sister chromatid exchange. Mol. Cell. Biol . 20, 3147-3156. doi: 10.1128/MCB.20.9.3147-3156.2000
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 3147-3156
    • Dronkert, M.L.1    Beverloo, H.B.2    Johnson, R.D.3    Hoeijmakers, J.H.4    Jasin, M.5    Kanaar, R.6
  • 38
    • 13444301307 scopus 로고    scopus 로고
    • Mechanism and control of V(D)J recombination versus class switch recombination: similarities and differences
    • doi: 10.1016/S0065-2776(04)86002-4
    • Dudley, D. D., Chaudhuri, J., Bassing, C. H., and Alt, F. W. (2005). Mechanism and control of V(D)J recombination versus class switch recombination: similarities and differences. Adv. Immunol . 86, 43-112. doi: 10.1016/S0065-2776(04)86002-4
    • (2005) Adv. Immunol. , vol.86 , pp. 43-112
    • Dudley, D.D.1    Chaudhuri, J.2    Bassing, C.H.3    Alt, F.W.4
  • 39
    • 0034922586 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae rad51 mutants are defective in DNA damage-associated sister chromatid exchanges but exhibit increased rates of homology-directed translocations.
    • Fasullo, M., Giallanza, P., Dong, Z., Cera, C., and Bennett, T. (2001). Saccharomyces cerevisiae rad51 mutants are defective in DNA damage-associated sister chromatid exchanges but exhibit increased rates of homology-directed translocations. Genetics 158, 959-972.
    • (2001) Genetics , vol.158 , pp. 959-972
    • Fasullo, M.1    Giallanza, P.2    Dong, Z.3    Cera, C.4    Bennett, T.5
  • 40
    • 0033592643 scopus 로고    scopus 로고
    • DNA double-strand break repair
    • doi: 10.1016/S0960-9822(00)80005-6
    • Featherstone, C., and Jackson, S. P. (1999). DNA double-strand break repair. Curr. Biol . 9, R759-R761. doi: 10.1016/S0960-9822(00)80005-6
    • (1999) Curr. Biol. , vol.9
    • Featherstone, C.1    Jackson, S.P.2
  • 41
    • 84857665369 scopus 로고    scopus 로고
    • Genomic architecture at the Incontinentia Pigmenti locus favours de novo pathological alleles through different mechanisms
    • doi: 10.1093/hmg/ddr556
    • Fusco, F., Paciolla, M., Napolitano, F., Pescatore, A., D'Addario, I., Bal, E., et al. (2012). Genomic architecture at the Incontinentia Pigmenti locus favours de novo pathological alleles through different mechanisms. Hum. Mol. Genet . 21, 1260-1271. doi: 10.1093/hmg/ddr556
    • (2012) Hum. Mol. Genet. , vol.21 , pp. 1260-1271
    • Fusco, F.1    Paciolla, M.2    Napolitano, F.3    Pescatore, A.4    D'Addario, I.5    Bal, E.6
  • 42
    • 0034119866 scopus 로고    scopus 로고
    • Homologous recombination is responsible for cell death in the absence of the Sgs1 and Srs2 helicases
    • doi: 10.1038/76055
    • Gangloff, S., Soustelle, C., and Fabre, F. (2000). Homologous recombination is responsible for cell death in the absence of the Sgs1 and Srs2 helicases. Nat. Genet . 25, 192-194. doi: 10.1038/76055
    • (2000) Nat. Genet. , vol.25 , pp. 192-194
    • Gangloff, S.1    Soustelle, C.2    Fabre, F.3
  • 43
    • 77954354375 scopus 로고    scopus 로고
    • The sigma(E) stress response is required for stress-induced mutation and amplification in Escherichia coli
    • doi: 10.1111/j.1365-2958.2010.07213.x
    • Gibson, J. L., Lombardo, M. J., Thornton, P. C., Hu, K. H., Galhardo, R. S., Beadle, B., et al. (2010). The sigma(E) stress response is required for stress-induced mutation and amplification in Escherichia coli. Mol. Microbiol . 77, 415-430. doi: 10.1111/j.1365-2958.2010.07213.x
    • (2010) Mol. Microbiol. , vol.77 , pp. 415-430
    • Gibson, J.L.1    Lombardo, M.J.2    Thornton, P.C.3    Hu, K.H.4    Galhardo, R.S.5    Beadle, B.6
  • 44
    • 0028577296 scopus 로고
    • Spontaneous and restriction enzyme-induced chromosomal recombination in mammalian cells
    • doi: 10.1073/pnas.91.26.12554
    • Godwin, A. R., Bollag, R. J., Christie, D. M., and Liskay, R. M. (1994). Spontaneous and restriction enzyme-induced chromosomal recombination in mammalian cells. Proc. Natl. Acad. Sci. U.S.A . 91, 12554-12558. doi: 10.1073/pnas.91.26.12554
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 12554-12558
    • Godwin, A.R.1    Bollag, R.J.2    Christie, D.M.3    Liskay, R.M.4
  • 45
    • 0242605613 scopus 로고    scopus 로고
    • Equal sister chromatid exchange is a major mechanism of double-strand break repair in yeast
    • doi: 10.1016/S1097-2765(03)00183-7
    • Gonzalez-Barrera, S., Cortes-Ledesma, F., Wellinger, R. E., and Aguilera, A. (2003). Equal sister chromatid exchange is a major mechanism of double-strand break repair in yeast. Mol. Cell 11, 1661-1671. doi: 10.1016/S1097-2765(03)00183-7
    • (2003) Mol. Cell , vol.11 , pp. 1661-1671
    • Gonzalez-Barrera, S.1    Cortes-Ledesma, F.2    Wellinger, R.E.3    Aguilera, A.4
  • 46
    • 78649629320 scopus 로고    scopus 로고
    • Oncogene-induced senescence: the bright and dark side of the response
    • doi: 10.1016/j.ceb.2010.07.013
    • Gorgoulis, V. G., and Halazonetis, T. D. (2010). Oncogene-induced senescence: the bright and dark side of the response. Curr. Opin. Cell Biol . 22, 816-827. doi: 10.1016/j.ceb.2010.07.013
    • (2010) Curr. Opin. Cell Biol. , vol.22 , pp. 816-827
    • Gorgoulis, V.G.1    Halazonetis, T.D.2
  • 47
    • 17244366865 scopus 로고    scopus 로고
    • Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
    • doi: 10.1038/nature03485
    • Gorgoulis, V. G., Vassiliou, L. V., Karakaidos, P., Zacharatos, P., Kotsinas, A., Liloglou, T., et al. (2005). Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions. Nature 434, 907-913. doi: 10.1038/nature03485
    • (2005) Nature , vol.434 , pp. 907-913
    • Gorgoulis, V.G.1    Vassiliou, L.V.2    Karakaidos, P.3    Zacharatos, P.4    Kotsinas, A.5    Liloglou, T.6
  • 48
    • 84871192059 scopus 로고    scopus 로고
    • Initiation of DNA double strand break repair: signaling and single-stranded resection dictate the choice between homologous recombination, non-homologous end-joining and alternative end-joining
    • Grabarz, A., Barascu, A., Guirouilh-Barbat, J., and Lopez, B. S. (2012). Initiation of DNA double strand break repair: signaling and single-stranded resection dictate the choice between homologous recombination, non-homologous end-joining and alternative end-joining. Am. J. Cancer Res . 2, 249-268.
    • (2012) Am. J. Cancer Res. , vol.2 , pp. 249-268
    • Grabarz, A.1    Barascu, A.2    Guirouilh-Barbat, J.3    Lopez, B.S.4
  • 49
    • 84885838052 scopus 로고    scopus 로고
    • A role for BLM in double-strand break repair pathway choice: prevention of CtIP/Mre11-mediated alternative nonhomologous end-joining
    • doi: 10.1016/j.celrep.2013.08.034
    • Grabarz, A., Guirouilh-Barbat, J., Barascu, A., Pennarun, G., Genet, D., Rass, E., et al. (2013). A role for BLM in double-strand break repair pathway choice: prevention of CtIP/Mre11-mediated alternative nonhomologous end-joining. Cell Rep . 5, 21-28. doi: 10.1016/j.celrep.2013.08.034
    • (2013) Cell Rep. , vol.5 , pp. 21-28
    • Grabarz, A.1    Guirouilh-Barbat, J.2    Barascu, A.3    Pennarun, G.4    Genet, D.5    Rass, E.6
  • 50
    • 33947101019 scopus 로고    scopus 로고
    • Patterns of somatic mutation in human cancer genomes
    • doi: 10.1038/nature05610
    • Greenman, C., Stephens, P., Smith, R., Dalgliesh, G. L., Hunter, C., Bignell, G., et al. (2007). Patterns of somatic mutation in human cancer genomes. Nature 446, 153-158. doi: 10.1038/nature05610
    • (2007) Nature , vol.446 , pp. 153-158
    • Greenman, C.1    Stephens, P.2    Smith, R.3    Dalgliesh, G.L.4    Hunter, C.5    Bignell, G.6
  • 51
    • 0034306365 scopus 로고    scopus 로고
    • Mammalian recombination-repair genes XRCC2 and XRCC3 promote correct chromosome segregation
    • doi: 10.1038/35036399
    • Griffin, C. S., Simpson, P. J., Wilson, C. R., and Thacker, J. (2000). Mammalian recombination-repair genes XRCC2 and XRCC3 promote correct chromosome segregation. Nat. Cell Biol . 2, 757-761. doi: 10.1038/35036399
    • (2000) Nat. Cell Biol. , vol.2 , pp. 757-761
    • Griffin, C.S.1    Simpson, P.J.2    Wilson, C.R.3    Thacker, J.4
  • 52
    • 79957998467 scopus 로고    scopus 로고
    • AKT1/BRCA1 in the control of homologous recombination and genetic stability: the missing link between hereditary and sporadic breast cancers.
    • Guirouilh-Barbat, J., Wilhelm, T., and Lopez, B. S. (2010). AKT1/BRCA1 in the control of homologous recombination and genetic stability: the missing link between hereditary and sporadic breast cancers. Oncotarget 1, 691-699.
    • (2010) Oncotarget , vol.1 , pp. 691-699
    • Guirouilh-Barbat, J.1    Wilhelm, T.2    Lopez, B.S.3
  • 53
    • 0026485543 scopus 로고
    • Mating-type gene switching in Saccharomyces cerevisiae
    • doi: 10.1016/0168-9525(92)90329-3
    • Haber, J. E. (1992). Mating-type gene switching in Saccharomyces cerevisiae. Trends Genet . 8, 446-452. doi: 10.1016/0168-9525(92)90329-3
    • (1992) Trends Genet. , vol.8 , pp. 446-452
    • Haber, J.E.1
  • 54
    • 84923848111 scopus 로고    scopus 로고
    • Genome Stability: DNA Repair and Recombinaition.
    • New York, NY: Garland Science.
    • Haber, J. E. (2014). Genome Stability: DNA Repair and Recombinaition . New York, NY: Garland Science.
    • (2014)
    • Haber, J.E.1
  • 55
    • 40449120350 scopus 로고    scopus 로고
    • An oncogene-induced DNA damage model for cancer development
    • doi: 10.1126/science.1140735
    • Halazonetis, T. D., Gorgoulis, V. G., and Bartek, J. (2008). An oncogene-induced DNA damage model for cancer development. Science 319, 1352-1355. doi: 10.1126/science.1140735
    • (2008) Science , vol.319 , pp. 1352-1355
    • Halazonetis, T.D.1    Gorgoulis, V.G.2    Bartek, J.3
  • 56
    • 0028292215 scopus 로고
    • Recombination in adaptive mutation
    • doi: 10.1126/science.8146657
    • Harris, R. S., Longerich, S., and Rosenberg, S. M. (1994). Recombination in adaptive mutation. Science 264, 258-260. doi: 10.1126/science.8146657
    • (1994) Science , vol.264 , pp. 258-260
    • Harris, R.S.1    Longerich, S.2    Rosenberg, S.M.3
  • 57
    • 78549251695 scopus 로고    scopus 로고
    • Rad51 protects nascent DNA from MRE11-dependent degradation and promotes continuous DNA synthesis
    • doi: 10.1038/nsmb.1927
    • Hashimoto, Y., Chaudhuri, A. R., Lopes, M., and Costanzo, V. (2010). Rad51 protects nascent DNA from MRE11-dependent degradation and promotes continuous DNA synthesis. Nat. Struct. Mol. Biol . 7, 1305-1311. doi: 10.1038/nsmb.1927
    • (2010) Nat. Struct. Mol. Biol. , vol.7 , pp. 1305-1311
    • Hashimoto, Y.1    Chaudhuri, A.R.2    Lopes, M.3    Costanzo, V.4
  • 58
    • 84855427966 scopus 로고    scopus 로고
    • RAD51- and MRE11-dependent reassembly of uncoupled CMG helicase complex at collapsed replication forks
    • doi: 10.1038/nsmb.2177
    • Hashimoto, Y., Puddu, F., and Costanzo, V. (2012). RAD51- and MRE11-dependent reassembly of uncoupled CMG helicase complex at collapsed replication forks. Nat. Struct. Mol. Biol . 19, 17-24. doi: 10.1038/nsmb.2177
    • (2012) Nat. Struct. Mol. Biol. , vol.19 , pp. 17-24
    • Hashimoto, Y.1    Puddu, F.2    Costanzo, V.3
  • 59
    • 59249105978 scopus 로고    scopus 로고
    • A microhomology-mediated break-induced replication model for the origin of human copy number variation.
    • doi: 10.1371/journal.pgen.1000327
    • Hastings, P. J., Ira, G., and Lupski, J. R. (2009). A microhomology-mediated break-induced replication model for the origin of human copy number variation. PLoS Genet . 5:e1000327. doi: 10.1371/journal.pgen.1000327
    • (2009) PLoS Genet. , vol.5
    • Hastings, P.J.1    Ira, G.2    Lupski, J.R.3
  • 60
    • 84888643083 scopus 로고    scopus 로고
    • Accelerated growth in the absence of DNA replication origins
    • doi: 10.1038/nature12650
    • Hawkins, M., Malla, S., Blythe, M. J., Nieduszynski, C. A., and Allers, T. (2013). Accelerated growth in the absence of DNA replication origins. Nature 503, 544-547. doi: 10.1038/nature12650
    • (2013) Nature , vol.503 , pp. 544-547
    • Hawkins, M.1    Malla, S.2    Blythe, M.J.3    Nieduszynski, C.A.4    Allers, T.5
  • 61
    • 77954328102 scopus 로고    scopus 로고
    • Increased mutagenesis and unique mutation signature associated with mitotic gene conversion
    • doi: 10.1126/science.1191125
    • Hicks, W. M., Kim, M., and Haber, J. E. (2010). Increased mutagenesis and unique mutation signature associated with mitotic gene conversion. Science 329, 82-85. doi: 10.1126/science.1191125
    • (2010) Science , vol.329 , pp. 82-85
    • Hicks, W.M.1    Kim, M.2    Haber, J.E.3
  • 62
    • 0032949351 scopus 로고    scopus 로고
    • Role for caspase-mediated cleavage of Rad51 in induction of apoptosis by DNA damage
    • Huang, Y., Nakada, S., Ishiko, T., Utsugisawa, T., Datta, R., Kharbanda, S., et al. (1999). Role for caspase-mediated cleavage of Rad51 in induction of apoptosis by DNA damage. Mol. Cell. Biol . 19, 2986-2997.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 2986-2997
    • Huang, Y.1    Nakada, S.2    Ishiko, T.3    Utsugisawa, T.4    Datta, R.5    Kharbanda, S.6
  • 63
    • 0033974047 scopus 로고    scopus 로고
    • Mechanisms and consequences of replication fork arrest
    • doi: 10.1016/S0300-9084(00)00344-8
    • Hyrien, O. (2000). Mechanisms and consequences of replication fork arrest. Biochimie 82, 5-17. doi: 10.1016/S0300-9084(00)00344-8
    • (2000) Biochimie , vol.82 , pp. 5-17
    • Hyrien, O.1
  • 65
    • 84868160005 scopus 로고    scopus 로고
    • Recovery of arrested replication forks by homologous recombination is error-prone.
    • doi: 10.1371/journal.pgen.1002976
    • Iraqui, I., Chekkal, Y., Jmari, N., Pietrobon, V., Freon, K., Costes, A., et al. (2012). Recovery of arrested replication forks by homologous recombination is error-prone. PLoS Genet . 8:e1002976. doi: 10.1371/journal.pgen.1002976
    • (2012) PLoS Genet. , vol.8
    • Iraqui, I.1    Chekkal, Y.2    Jmari, N.3    Pietrobon, V.4    Freon, K.5    Costes, A.6
  • 66
    • 0348047594 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae helicase Rrm3p facilitates replication past nonhistone protein-DNA complexes
    • doi: 10.1016/S1097-2765(03)00456-8
    • Ivessa, A. S., Lenzmeier, B. A., Bessler, J. B., Goudsouzian, L. K., Schnakenberg, S. L., and Zakian, V. A. (2003). The Saccharomyces cerevisiae helicase Rrm3p facilitates replication past nonhistone protein-DNA complexes. Mol. Cell . 12, 1525-1536. doi: 10.1016/S1097-2765(03)00456-8
    • (2003) Mol. Cell. , vol.12 , pp. 1525-1536
    • Ivessa, A.S.1    Lenzmeier, B.A.2    Bessler, J.B.3    Goudsouzian, L.K.4    Schnakenberg, S.L.5    Zakian, V.A.6
  • 67
    • 77957731999 scopus 로고    scopus 로고
    • Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma
    • doi: 10.1126/science.1196333
    • Jones, S., Wang, T. L., Shih, I., Mao, T. L., Nakayama, K., Roden, R., et al. (2010). Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma. Science 330, 228-231. doi: 10.1126/science.1196333
    • (2010) Science , vol.330 , pp. 228-231
    • Jones, S.1    Wang, T.L.2    Shih, I.3    Mao, T.L.4    Nakayama, K.5    Roden, R.6
  • 68
    • 0842303307 scopus 로고    scopus 로고
    • Unraveling V(D)J recombination; insights into gene regulation
    • doi: 10.1016/S0092-8674(04)00039-X
    • Jung, D., and Alt, F. W. (2004). Unraveling V(D)J recombination; insights into gene regulation. Cell 116, 299-311. doi: 10.1016/S0092-8674(04)00039-X
    • (2004) Cell , vol.116 , pp. 299-311
    • Jung, D.1    Alt, F.W.2
  • 69
    • 67651163668 scopus 로고    scopus 로고
    • The ATR-Chk1 pathway plays a role in the generation of centrosome aberrations induced by Rad51C dysfunction
    • doi: 10.1093/nar/gkp262
    • Katsura, M., Tsuruga, T., Date, O., Yoshihara, T., Ishida, M., Tomoda, Y., et al. (2009). The ATR-Chk1 pathway plays a role in the generation of centrosome aberrations induced by Rad51C dysfunction. Nucleic Acids Res . 37, 3959-3968. doi: 10.1093/nar/gkp262
    • (2009) Nucleic Acids Res. , vol.37 , pp. 3959-3968
    • Katsura, M.1    Tsuruga, T.2    Date, O.3    Yoshihara, T.4    Ishida, M.5    Tomoda, Y.6
  • 70
    • 84455192643 scopus 로고    scopus 로고
    • Regulation of arginine acquisition and virulence gene expression in the human pathogen Streptococcus pneumoniae by transcription regulators ArgR1 and AhrC
    • doi: 10.1074/jbc.M111.295832
    • Kloosterman, T. G., and Kuipers, O. P. (2011). Regulation of arginine acquisition and virulence gene expression in the human pathogen Streptococcus pneumoniae by transcription regulators ArgR1 and AhrC. J. Biol. Chem . 286, 44594-44605. doi: 10.1074/jbc.M111.295832
    • (2011) J. Biol. Chem. , vol.286 , pp. 44594-44605
    • Kloosterman, T.G.1    Kuipers, O.P.2
  • 71
    • 0020574485 scopus 로고
    • Genetic exchanges between partially homologous nucleotide sequences: possible implications for multigene families
    • doi: 10.1016/S0300-9084(83)80178-3
    • Kourilsky, P. (1983). Genetic exchanges between partially homologous nucleotide sequences: possible implications for multigene families. Biochimie 65, 85-93. doi: 10.1016/S0300-9084(83)80178-3
    • (1983) Biochimie , vol.65 , pp. 85-93
    • Kourilsky, P.1
  • 72
    • 0036136316 scopus 로고    scopus 로고
    • Brca2 (XRCC11) deficiency results in radioresistant DNA synthesis and a higher frequency of spontaneous deletions
    • doi: 10.1128/MCB.22.2.669-679.2002
    • Kraakman-van der Zwet, M., Overkamp, W. J., van Lange, R. E., Essers, J., van Duijn-Goedhart, A., Wiggers, I., et al. (2002). Brca2 (XRCC11) deficiency results in radioresistant DNA synthesis and a higher frequency of spontaneous deletions. Mol. Cell. Biol . 22, 669-679. doi: 10.1128/MCB.22.2.669-679.2002
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 669-679
    • Kraakman-van der Zwet, M.1    Overkamp, W.J.2    van Lange, R.E.3    Essers, J.4    van Duijn-Goedhart, A.5    Wiggers, I.6
  • 73
    • 0035902459 scopus 로고    scopus 로고
    • Break-induced replication: a review and an example in budding yeast
    • doi: 10.1073/pnas.151008198
    • Kraus, E., Leung, W. Y., and Haber, J. E. (2001). Break-induced replication: a review and an example in budding yeast. Proc. Natl. Acad. Sci. U.S.A . 98, 8255-8262. doi: 10.1073/pnas.151008198
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 8255-8262
    • Kraus, E.1    Leung, W.Y.2    Haber, J.E.3
  • 74
    • 0026575429 scopus 로고
    • Duplication-targeted DNA methylation and mutagenesis in the evolution of eukaryotic chromosomes
    • doi: 10.1073/pnas.89.3.1075
    • Kricker, M. C., Drake, J. W., and Radman, M. (1992). Duplication-targeted DNA methylation and mutagenesis in the evolution of eukaryotic chromosomes. Proc. Natl. Acad. Sci. U.S.A . 89, 1075-1079. doi: 10.1073/pnas.89.3.1075
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 1075-1079
    • Kricker, M.C.1    Drake, J.W.2    Radman, M.3
  • 75
    • 80054751998 scopus 로고    scopus 로고
    • Exome sequencing identifies a spectrum of mutation frequencies in advanced and lethal prostate cancers
    • doi: 10.1073/pnas.1108745108
    • Kumar, A., White, T. A., MacKenzie, A. P., Clegg, N., Lee, C., Dumpit, R. F., et al. (2011). Exome sequencing identifies a spectrum of mutation frequencies in advanced and lethal prostate cancers. Proc. Natl. Acad. Sci. U.S.A . 108, 17087-17092. doi: 10.1073/pnas.1108745108
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 17087-17092
    • Kumar, A.1    White, T.A.2    MacKenzie, A.P.3    Clegg, N.4    Lee, C.5    Dumpit, R.F.6
  • 77
    • 21244448288 scopus 로고    scopus 로고
    • Checkpoint responses to replication fork barriers
    • doi: 10.1016/j.biochi.2004.10.020
    • Lambert, S., and Carr, A. M. (2005). Checkpoint responses to replication fork barriers. Biochimie . 87, 591-602. doi: 10.1016/j.biochi.2004.10.020
    • (2005) Biochimie. , vol.87 , pp. 591-602
    • Lambert, S.1    Carr, A.M.2
  • 78
    • 84876491816 scopus 로고    scopus 로고
    • Impediments to replication fork movement: stabilisation, reactivation and genome instability
    • doi: 10.1007/s00412-013-0398-9
    • Lambert, S., and Carr, A. M. (2013). Impediments to replication fork movement: stabilisation, reactivation and genome instability. Chromosoma 122, 33-45. doi: 10.1007/s00412-013-0398-9
    • (2013) Chromosoma , vol.122 , pp. 33-45
    • Lambert, S.1    Carr, A.M.2
  • 79
    • 0034660620 scopus 로고    scopus 로고
    • Characterization of mammalian RAD51 double strand break repair using non lethal dominant negative forms
    • doi: 10.1093/emboj/19.12.3090
    • Lambert, S., and Lopez, B. S. (2000). Characterization of mammalian RAD51 double strand break repair using non lethal dominant negative forms. EMBO J . 19, 3090-3099. doi: 10.1093/emboj/19.12.3090
    • (2000) EMBO J. , vol.19 , pp. 3090-3099
    • Lambert, S.1    Lopez, B.S.2
  • 80
    • 0035807217 scopus 로고    scopus 로고
    • Role of RAD51 in sister-chromatid exchanges in mammalian cells
    • doi: 10.1038/sj.onc.1204813
    • Lambert, S., and Lopez, B. S. (2001). Role of RAD51 in sister-chromatid exchanges in mammalian cells. Oncogene 20, 6627-6631. doi: 10.1038/sj.onc.1204813
    • (2001) Oncogene , vol.20 , pp. 6627-6631
    • Lambert, S.1    Lopez, B.S.2
  • 81
    • 0037030467 scopus 로고    scopus 로고
    • Inactivation of the RAD51 recombination pathway stimulates UV-induced mutagenesis in mammalian cells
    • doi: 10.1038/sj.onc.1205535
    • Lambert, S., and Lopez, B. S. (2002). Inactivation of the RAD51 recombination pathway stimulates UV-induced mutagenesis in mammalian cells. Oncogene 21, 4065-4069. doi: 10.1038/sj.onc.1205535
    • (2002) Oncogene , vol.21 , pp. 4065-4069
    • Lambert, S.1    Lopez, B.S.2
  • 82
    • 77955479780 scopus 로고    scopus 로고
    • Homologous recombination restarts blocked replication forks at the expense of genome rearrangements by template exchange
    • doi: 10.1016/j.molcel.2010.07.015
    • Lambert, S., Mizuno, K., Blaisonneau, J., Martineau, S., Chanet, R., Freon, K., et al. (2010). Homologous recombination restarts blocked replication forks at the expense of genome rearrangements by template exchange. Mol. Cell . 39, 346-359. doi: 10.1016/j.molcel.2010.07.015
    • (2010) Mol. Cell. , vol.39 , pp. 346-359
    • Lambert, S.1    Mizuno, K.2    Blaisonneau, J.3    Martineau, S.4    Chanet, R.5    Freon, K.6
  • 83
    • 20444424939 scopus 로고    scopus 로고
    • Gross chromosomal rearrangements and elevated recombination at an inducible site-specific replication fork barrier
    • doi: 10.1016/j.cell.2005.03.022
    • Lambert, S., Watson, A., Sheedy, D. M., Martin, B., and Carr, A. M. (2005). Gross chromosomal rearrangements and elevated recombination at an inducible site-specific replication fork barrier. Cell 121, 689-702. doi: 10.1016/j.cell.2005.03.022
    • (2005) Cell , vol.121 , pp. 689-702
    • Lambert, S.1    Watson, A.2    Sheedy, D.M.3    Martin, B.4    Carr, A.M.5
  • 84
    • 79955530503 scopus 로고    scopus 로고
    • APOBEC3A can activate the DNA damage response and cause cell-cycle arrest
    • doi: 10.1038/embor.2011.46
    • Landry, S., Narvaiza, I., Linfesty, D. C., and Weitzman, M. D. (2011). APOBEC3A can activate the DNA damage response and cause cell-cycle arrest. EMBO Rep . 12, 444-450. doi: 10.1038/embor.2011.46
    • (2011) EMBO Rep. , vol.12 , pp. 444-450
    • Landry, S.1    Narvaiza, I.2    Linfesty, D.C.3    Weitzman, M.D.4
  • 85
    • 84975685847 scopus 로고    scopus 로고
    • From sequence to molecular pathology, and a mechanism driving the neuroendocrine phenotype in prostate cancer
    • doi: 10.1002/path.4047
    • Lapuk, A. V., Wu, C., Wyatt, A. W., McPherson, A., McConeghy, B. J., Brahmbhatt, S., et al. (2012). From sequence to molecular pathology, and a mechanism driving the neuroendocrine phenotype in prostate cancer. J. Pathol . 227, 286-297. doi: 10.1002/path.4047
    • (2012) J. Pathol. , vol.227 , pp. 286-297
    • Lapuk, A.V.1    Wu, C.2    Wyatt, A.W.3    McPherson, A.4    McConeghy, B.J.5    Brahmbhatt, S.6
  • 86
    • 79956118019 scopus 로고    scopus 로고
    • Bcl-2 inhibits nuclear homologous recombination by localizing BRCA1 to the endomembranes
    • doi: 10.1158/0008-5472.CAN-10-3119
    • Laulier, C., Barascu, A., Guirouilh-Barbat, J., Pennarun, G., Le Chalony, C., Chevalier, F., et al. (2011a). Bcl-2 inhibits nuclear homologous recombination by localizing BRCA1 to the endomembranes. Cancer Res . 71, 3590-3602. doi: 10.1158/0008-5472.CAN-10-3119
    • (2011) Cancer Res. , vol.71 , pp. 3590-3602
    • Laulier, C.1    Barascu, A.2    Guirouilh-Barbat, J.3    Pennarun, G.4    Le Chalony, C.5    Chevalier, F.6
  • 87
    • 80051772864 scopus 로고    scopus 로고
    • The relative efficiency of homology-directed repair has distinct effects on proper anaphase chromosome separation
    • doi: 10.1093/nar/gkr187
    • Laulier, C., Cheng, A., and Stark, J. M. (2011b). The relative efficiency of homology-directed repair has distinct effects on proper anaphase chromosome separation. Nucleic Acids Res . 39, 5935-5944. doi: 10.1093/nar/gkr187
    • (2011) Nucleic Acids Res. , vol.39 , pp. 5935-5944
    • Laulier, C.1    Cheng, A.2    Stark, J.M.3
  • 88
    • 84865644725 scopus 로고    scopus 로고
    • The secret life of Bcl-2: Apoptosis-independent inhibition of DNA repair by Bcl-2 family members
    • doi: 10.1016/j.mrrev.2012.05.002
    • Laulier, C., and Lopez, B. S. (2012). The secret life of Bcl-2: Apoptosis-independent inhibition of DNA repair by Bcl-2 family members. Mutat. Res . 751, 247-257. doi: 10.1016/j.mrrev.2012.05.002
    • (2012) Mutat. Res. , vol.751 , pp. 247-257
    • Laulier, C.1    Lopez, B.S.2
  • 89
    • 37349109667 scopus 로고    scopus 로고
    • A DNA replication mechanism for generating nonrecurrent rearrangements associated with genomic disorders
    • doi: 10.1016/j.cell.2007.11.037
    • Lee, J. A., Carvalho, C. M., and Lupski, J. R. (2007). A DNA replication mechanism for generating nonrecurrent rearrangements associated with genomic disorders. Cell 131, 1235-1247. doi: 10.1016/j.cell.2007.11.037
    • (2007) Cell , vol.131 , pp. 1235-1247
    • Lee, J.A.1    Carvalho, C.M.2    Lupski, J.R.3
  • 90
    • 50249159576 scopus 로고    scopus 로고
    • Reduced levels of DNA polymerase delta induce chromosome fragile site instability in yeast
    • doi: 10.1128/MCB.02084-07
    • Lemoine, F. J., Degtyareva, N. P., Kokoska, R. J., and Petes, T. D. (2008). Reduced levels of DNA polymerase delta induce chromosome fragile site instability in yeast. Mol. Cell. Biol . 28, 5359-5368. doi: 10.1128/MCB.02084-07
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 5359-5368
    • Lemoine, F.J.1    Degtyareva, N.P.2    Kokoska, R.J.3    Petes, T.D.4
  • 91
    • 14844286404 scopus 로고    scopus 로고
    • Chromosomal translocations in yeast induced by low levels of DNA polymerase a model for chromosome fragile sites
    • doi: 10.1016/j.cell.2004.12.039
    • Lemoine, F. J., Degtyareva, N. P., Lobachev, K., and Petes, T. D. (2005). Chromosomal translocations in yeast induced by low levels of DNA polymerase a model for chromosome fragile sites. Cell 120, 587-598. doi: 10.1016/j.cell.2004.12.039
    • (2005) Cell , vol.120 , pp. 587-598
    • Lemoine, F.J.1    Degtyareva, N.P.2    Lobachev, K.3    Petes, T.D.4
  • 92
    • 0033360956 scopus 로고    scopus 로고
    • Concerted evolution: molecular mechanism and biological implications
    • doi: 10.1086/302221
    • Liao, D. (1999). Concerted evolution: molecular mechanism and biological implications. Am. J. Hum. Genet . 64, 24-30. doi: 10.1086/302221
    • (1999) Am. J. Hum. Genet. , vol.64 , pp. 24-30
    • Liao, D.1
  • 93
    • 0024419449 scopus 로고
    • Position effects in ectopic and allelic mitotic recombination in Saccharomyces cerevisiae.
    • Lichten, M., and Haber, J. E. (1989). Position effects in ectopic and allelic mitotic recombination in Saccharomyces cerevisiae. Genetics 123, 261-268.
    • (1989) Genetics , vol.123 , pp. 261-268
    • Lichten, M.1    Haber, J.E.2
  • 94
    • 3242879122 scopus 로고    scopus 로고
    • The mechanism of vertebrate nonhomologous DNA end joining and its role in V(D)J recombination
    • doi: 10.1016/j.dnarep.2004.03.015
    • Lieber, M. R., Ma, Y., Pannicke, U., and Schwarz, K. (2004). The mechanism of vertebrate nonhomologous DNA end joining and its role in V(D)J recombination. DNA Repair (Amst.) 3, 817-826. doi: 10.1016/j.dnarep.2004.03.015
    • (2004) DNA Repair (Amst.) , vol.3 , pp. 817-826
    • Lieber, M.R.1    Ma, Y.2    Pannicke, U.3    Schwarz, K.4
  • 95
    • 0032061317 scopus 로고    scopus 로고
    • XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages
    • doi: 10.1016/S1097-2765(00)80078-7
    • Liu, N., Lamerdin, J. E., Tebbs, R. S., Schild, D., Tucker, J. D., Shen, M. R., et al. (1998). XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages. Mol. Cell . 1, 783-793. doi: 10.1016/S1097-2765(00)80078-7
    • (1998) Mol. Cell. , vol.1 , pp. 783-793
    • Liu, N.1    Lamerdin, J.E.2    Tebbs, R.S.3    Schild, D.4    Tucker, J.D.5    Shen, M.R.6
  • 96
    • 80052916562 scopus 로고    scopus 로고
    • Chromosome catastrophes involve replication mechanisms generating complex genomic rearrangements
    • doi: 10.1016/j.cell.2011.07.042
    • Liu, P., Erez, A., Nagamani, S. C., Dhar, S. U., Kolodziejska, K. E., Dharmadhikari, A. V., et al. (2011). Chromosome catastrophes involve replication mechanisms generating complex genomic rearrangements. Cell 146, 889-903. doi: 10.1016/j.cell.2011.07.042
    • (2011) Cell , vol.146 , pp. 889-903
    • Liu, P.1    Erez, A.2    Nagamani, S.C.3    Dhar, S.U.4    Kolodziejska, K.E.5    Dharmadhikari, A.V.6
  • 97
    • 79959843168 scopus 로고    scopus 로고
    • Mechanism of RAD51-dependent DNA interstrand cross-link repair
    • doi: 10.1126/science.1204258
    • Long, D. T., Raschle, M., Joukov, V., and Walter, J. C. (2011). Mechanism of RAD51-dependent DNA interstrand cross-link repair. Science 333, 84-87. doi: 10.1126/science.1204258
    • (2011) Science , vol.333 , pp. 84-87
    • Long, D.T.1    Raschle, M.2    Joukov, V.3    Walter, J.C.4
  • 98
    • 34547927220 scopus 로고    scopus 로고
    • Break-induced replication and telomerase-independent telomere maintenance require Pol32
    • doi: 10.1038/nature06047
    • Lydeard, J. R., Jain, S., Yamaguchi, M., and Haber, J. E. (2007). Break-induced replication and telomerase-independent telomere maintenance require Pol32. Nature 448, 820-823. doi: 10.1038/nature06047
    • (2007) Nature , vol.448 , pp. 820-823
    • Lydeard, J.R.1    Jain, S.2    Yamaguchi, M.3    Haber, J.E.4
  • 99
    • 77953076932 scopus 로고    scopus 로고
    • Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly
    • doi: 10.1101/gad.1922610
    • Lydeard, J. R., Lipkin-Moore, Z., Sheu, Y. J., Stillman, B., Burgers, P. M., and Haber, J. E. (2010). Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly. Genes Dev . 24, 1133-1144. doi: 10.1101/gad.1922610
    • (2010) Genes Dev. , vol.24 , pp. 1133-1144
    • Lydeard, J.R.1    Lipkin-Moore, Z.2    Sheu, Y.J.3    Stillman, B.4    Burgers, P.M.5    Haber, J.E.6
  • 100
    • 79960693423 scopus 로고    scopus 로고
    • Chromothripsis identifies a rare and aggressive entity among newly diagnosed multiple myeloma patients
    • doi: 10.1182/blood-2011-03-344069
    • Magrangeas, F., Avet-Loiseau, H., Munshi, N. C., and Minvielle, S. (2011). Chromothripsis identifies a rare and aggressive entity among newly diagnosed multiple myeloma patients. Blood 118, 675-678. doi: 10.1182/blood-2011-03-344069
    • (2011) Blood , vol.118 , pp. 675-678
    • Magrangeas, F.1    Avet-Loiseau, H.2    Munshi, N.C.3    Minvielle, S.4
  • 101
    • 59849089955 scopus 로고    scopus 로고
    • Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining
    • doi: 10.1042/BJ20080413
    • Mahaney, B. L., Meek, K., and Lees-Miller, S. P. (2009). Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining. Biochem. J . 417, 639-650. doi: 10.1042/BJ20080413
    • (2009) Biochem. J. , vol.417 , pp. 639-650
    • Mahaney, B.L.1    Meek, K.2    Lees-Miller, S.P.3
  • 102
    • 34248651591 scopus 로고    scopus 로고
    • VSGdb: a database for trypanosome variant surface glycoproteins, a large and diverse family of coiled coil proteins.
    • doi: 10.1186/1471-2105-8-143
    • Marcello, L., Menon, S., Ward, P., Wilkes, J. M., Jones, N. G., Carrington, M., et al. (2007). VSGdb: a database for trypanosome variant surface glycoproteins, a large and diverse family of coiled coil proteins. BMC Bioinformatics . 8:143. doi: 10.1186/1471-2105-8-143
    • (2007) BMC Bioinformatics. , vol.8 , pp. 143
    • Marcello, L.1    Menon, S.2    Ward, P.3    Wilkes, J.M.4    Jones, N.G.5    Carrington, M.6
  • 103
    • 72849150228 scopus 로고    scopus 로고
    • Nearby inverted repeats fuse to generate acentric and dicentric palindromic chromosomes by a replication template exchange mechanism
    • doi: 10.1101/gad.1863009
    • Mizuno, K., Lambert, S., Baldacci, G., Murray, J. M., and Carr, A. M. (2009). Nearby inverted repeats fuse to generate acentric and dicentric palindromic chromosomes by a replication template exchange mechanism. Genes Dev . 23, 2876-2886. doi: 10.1101/gad.1863009
    • (2009) Genes Dev. , vol.23 , pp. 2876-2886
    • Mizuno, K.1    Lambert, S.2    Baldacci, G.3    Murray, J.M.4    Carr, A.M.5
  • 104
    • 84872138637 scopus 로고    scopus 로고
    • Recombination-restarted replication makes inverted chromosome fusions at inverted repeats
    • doi: 10.1038/nature11676
    • Mizuno, K., Miyabe, I., Schalbetter, S. A., Carr, A. M., and Murray, J. M. (2013). Recombination-restarted replication makes inverted chromosome fusions at inverted repeats. Nature 493, 246-249. doi: 10.1038/nature11676
    • (2013) Nature , vol.493 , pp. 246-249
    • Mizuno, K.1    Miyabe, I.2    Schalbetter, S.A.3    Carr, A.M.4    Murray, J.M.5
  • 105
    • 84859216598 scopus 로고    scopus 로고
    • Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes
    • doi: 10.1038/nature10910
    • Molenaar, J. J., Koster, J., Zwijnenburg, D. A., van Sluis, P., Valentijn, L. J., van der Ploeg, I., et al. (2012). Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes. Nature 483, 589-593. doi: 10.1038/nature10910
    • (2012) Nature , vol.483 , pp. 589-593
    • Molenaar, J.J.1    Koster, J.2    Zwijnenburg, D.A.3    van Sluis, P.4    Valentijn, L.J.5    van der Ploeg, I.6
  • 106
    • 77649264634 scopus 로고    scopus 로고
    • A postincision-deficient TFIIH causes replication fork breakage and uncovers alternative Rad51- or Pol32-mediated restart mechanisms
    • doi: 10.1016/j.molcel.2010.02.008
    • Moriel-Carretero, M., and Aguilera, A. (2010). A postincision-deficient TFIIH causes replication fork breakage and uncovers alternative Rad51- or Pol32-mediated restart mechanisms. Mol. Cell . 37, 690-701. doi: 10.1016/j.molcel.2010.02.008
    • (2010) Mol. Cell. , vol.37 , pp. 690-701
    • Moriel-Carretero, M.1    Aguilera, A.2
  • 107
    • 72749109190 scopus 로고    scopus 로고
    • Antigenic variation in the African trypanosome: molecular mechanisms and phenotypic complexity
    • doi: 10.1111/j.1462-5822.2009.01383.x
    • Morrison, L. J., Marcello, L., and McCulloch, R. (2009). Antigenic variation in the African trypanosome: molecular mechanisms and phenotypic complexity. Cell. Microbiol . 11, 1724-1734. doi: 10.1111/j.1462-5822.2009.01383.x
    • (2009) Cell. Microbiol. , vol.11 , pp. 1724-1734
    • Morrison, L.J.1    Marcello, L.2    McCulloch, R.3
  • 108
    • 0033213392 scopus 로고    scopus 로고
    • Brca1 controls homology-directed DNA repair
    • doi: 10.1016/S1097-2765(00)80202-6
    • Moynahan, M. E., Chiu, J. W., Koller, B. H., and Jasin, M. (1999). Brca1 controls homology-directed DNA repair. Mol. Cell . 4, 511-518. doi: 10.1016/S1097-2765(00)80202-6
    • (1999) Mol. Cell. , vol.4 , pp. 511-518
    • Moynahan, M.E.1    Chiu, J.W.2    Koller, B.H.3    Jasin, M.4
  • 109
    • 0035099044 scopus 로고    scopus 로고
    • BRCA2 is required for homology-directed repair of chromosomal breaks
    • doi: 10.1016/S1097-2765(01)00174-5
    • Moynahan, M. E., Pierce, A. J., and Jasin, M. (2001). BRCA2 is required for homology-directed repair of chromosomal breaks. Mol. Cell . 7, 263-272. doi: 10.1016/S1097-2765(01)00174-5
    • (2001) Mol. Cell. , vol.7 , pp. 263-272
    • Moynahan, M.E.1    Pierce, A.J.2    Jasin, M.3
  • 110
    • 84861541343 scopus 로고    scopus 로고
    • Mutational processes molding the genomes of 21 breast cancers
    • doi: 10.1016/j.cell.2012.04.024
    • Nik-Zainal, S., Alexandrov, L. B., Wedge, D. C., Van Loo, P., Greenman, C. D., Raine, K., et al. (2012). Mutational processes molding the genomes of 21 breast cancers. Cell 149, 979-993. doi: 10.1016/j.cell.2012.04.024
    • (2012) Cell , vol.149 , pp. 979-993
    • Nik-Zainal, S.1    Alexandrov, L.B.2    Wedge, D.C.3    Van Loo, P.4    Greenman, C.D.5    Raine, K.6
  • 111
    • 34547962985 scopus 로고    scopus 로고
    • Gene conversion is a convergent strategy for pathogen antigenic variation
    • doi: 10.1016/j.pt.2007.07.008
    • Palmer, G. H., and Brayton, K. A. (2007). Gene conversion is a convergent strategy for pathogen antigenic variation. Trends Parasitol . 23, 408-413. doi: 10.1016/j.pt.2007.07.008
    • (2007) Trends Parasitol. , vol.23 , pp. 408-413
    • Palmer, G.H.1    Brayton, K.A.2
  • 112
    • 84866911161 scopus 로고    scopus 로고
    • Complex chromosomal rearrangements mediated by break-induced replication involve structure-selective endonucleases.
    • doi: 10.1371/journal.pgen.1002979
    • Pardo, B., and Aguilera, A. (2012). Complex chromosomal rearrangements mediated by break-induced replication involve structure-selective endonucleases. PLoS Genet . 8:e1002979. doi: 10.1371/journal.pgen.1002979
    • (2012) PLoS Genet. , vol.8
    • Pardo, B.1    Aguilera, A.2
  • 113
    • 79251629946 scopus 로고    scopus 로고
    • The genetic landscape of the childhood cancer medulloblastoma
    • doi: 10.1126/science.1198056
    • Parsons, D. W., Li, M., Zhang, X., Jones, S., Leary, R. J., Lin, J. C., et al. (2011). The genetic landscape of the childhood cancer medulloblastoma. Science 331, 435-439. doi: 10.1126/science.1198056
    • (2011) Science , vol.331 , pp. 435-439
    • Parsons, D.W.1    Li, M.2    Zhang, X.3    Jones, S.4    Leary, R.J.5    Lin, J.C.6
  • 114
    • 56449128931 scopus 로고    scopus 로고
    • AKT1 inhibits homologous recombination by inducing cytoplasmic retention of BRCA1 and RAD51
    • doi: 10.1158/0008-5472.CAN-08-0861
    • Plo, I., Laulier, C., Gauthier, L., Lebrun, F., Calvo, F., and Lopez, B. S. (2008). AKT1 inhibits homologous recombination by inducing cytoplasmic retention of BRCA1 and RAD51. Cancer Res . 68, 9404-9412. doi: 10.1158/0008-5472.CAN-08-0861
    • (2008) Cancer Res. , vol.68 , pp. 9404-9412
    • Plo, I.1    Laulier, C.2    Gauthier, L.3    Lebrun, F.4    Calvo, F.5    Lopez, B.S.6
  • 115
    • 67349281546 scopus 로고    scopus 로고
    • AKT1 represses gene conversion induced by different genotoxic stresses and induces supernumerary centrosomes and aneuploidy in hamster ovary cells
    • doi: 10.1038/onc.2009.85
    • Plo, I., and Lopez, B. (2009). AKT1 represses gene conversion induced by different genotoxic stresses and induces supernumerary centrosomes and aneuploidy in hamster ovary cells. Oncogene 28, 2231-2237. doi: 10.1038/onc.2009.85
    • (2009) Oncogene , vol.28 , pp. 2231-2237
    • Plo, I.1    Lopez, B.2
  • 116
    • 24944477416 scopus 로고    scopus 로고
    • A switch from high-fidelity to error-prone DNA double-strand break repair underlies stress-induced mutation
    • doi: 10.1016/j.molcel.2005.07.025
    • Ponder, R. G., Fonville, N. C., and Rosenberg, S. M. (2005). A switch from high-fidelity to error-prone DNA double-strand break repair underlies stress-induced mutation. Mol. Cell . 19, 791-804. doi: 10.1016/j.molcel.2005.07.025
    • (2005) Mol. Cell. , vol.19 , pp. 791-804
    • Ponder, R.G.1    Fonville, N.C.2    Rosenberg, S.M.3
  • 117
    • 84868240146 scopus 로고    scopus 로고
    • Ploidy and large-scale genomic instability consistently identify basal-like breast carcinomas with BRCA1/2 inactivation
    • doi: 10.1158/0008-5472.CAN-12-1470
    • Popova, T., Manie, E., Rieunier, G., Caux-Moncoutier, V., Tirapo, C., Dubois, T., et al. (2012). Ploidy and large-scale genomic instability consistently identify basal-like breast carcinomas with BRCA1/2 inactivation. Cancer Res . 72, 5454-5462. doi: 10.1158/0008-5472.CAN-12-1470
    • (2012) Cancer Res. , vol.72 , pp. 5454-5462
    • Popova, T.1    Manie, E.2    Rieunier, G.3    Caux-Moncoutier, V.4    Tirapo, C.5    Dubois, T.6
  • 118
    • 0030929515 scopus 로고    scopus 로고
    • Recombination hot spots and human disease
    • Purandare, S. M., and Patel, P. I. (1997). Recombination hot spots and human disease. Genome Res . 7, 773-786.
    • (1997) Genome Res. , vol.7 , pp. 773-786
    • Purandare, S.M.1    Patel, P.I.2
  • 119
    • 0019291994 scopus 로고
    • The origin of spontaneous mutation in Saccharomyces cerevisiae.
    • Quah, S. K., von Borstel, R. C., and Hastings, P. J. (1980). The origin of spontaneous mutation in Saccharomyces cerevisiae. Genetics 96, 819-839.
    • (1980) Genetics , vol.96 , pp. 819-839
    • Quah, S.K.1    von Borstel, R.C.2    Hastings, P.J.3
  • 120
    • 84857457722 scopus 로고    scopus 로고
    • [Double Strand Break Repair, one mechanism can hide another: alternative non-homologous end joining.]
    • doi: 10.1016/j.canrad.2011.05.004
    • Rass, E., Grabarz, A., Bertrand, P., and Lopez, B. S. (2012). [Double Strand Break Repair, one mechanism can hide another: alternative non-homologous end joining.]. Cancer Radiother . 16, 1-10. doi: 10.1016/j.canrad.2011.05.004
    • (2012) Cancer Radiother. , vol.16 , pp. 1-10
    • Rass, E.1    Grabarz, A.2    Bertrand, P.3    Lopez, B.S.4
  • 121
    • 0036861699 scopus 로고    scopus 로고
    • The roles of REV3 and RAD57 in double-strand-break-repair-induced mutagenesis of Saccharomyces cerevisiae
    • Rattray, A. J., Shafer, B. K., McGill, C. B., and Strathern, J. N. (2002). The roles of REV3 and RAD57 in double-strand-break-repair-induced mutagenesis of Saccharomyces cerevisiae. Genetics 162, 1063-1077.
    • (2002) Genetics , vol.162 , pp. 1063-1077
    • Rattray, A.J.1    Shafer, B.K.2    McGill, C.B.3    Strathern, J.N.4
  • 122
    • 84862907577 scopus 로고    scopus 로고
    • Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations
    • doi: 10.1016/j.cell.2011.12.013
    • Rausch, T., Jones, D. T., Zapatka, M., Stutz, A. M., Zichner, T., Weischenfeldt, J., et al. (2012). Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations. Cell 148, 59-71. doi: 10.1016/j.cell.2011.12.013
    • (2012) Cell , vol.148 , pp. 59-71
    • Rausch, T.1    Jones, D.T.2    Zapatka, M.3    Stutz, A.M.4    Zichner, T.5    Weischenfeldt, J.6
  • 123
    • 0023652339 scopus 로고
    • A hyperconversion mechanism generates the chicken light chain preimmune repertoire
    • doi: 10.1016/0092-8674(87)90189-9
    • Reynaud, C. A., Anquez, V., Grimal, H., and Weill, J. C. (1987). A hyperconversion mechanism generates the chicken light chain preimmune repertoire. Cell 48, 379-388. doi: 10.1016/0092-8674(87)90189-9
    • (1987) Cell , vol.48 , pp. 379-388
    • Reynaud, C.A.1    Anquez, V.2    Grimal, H.3    Weill, J.C.4
  • 124
    • 0842329805 scopus 로고    scopus 로고
    • Rad51 overexpression promotes alternative double-strand break repair pathways and genome instability
    • doi: 10.1038/sj.onc.1207098
    • Richardson, C., Stark, J. M., Ommundsen, M., and Jasin, M. (2004). Rad51 overexpression promotes alternative double-strand break repair pathways and genome instability. Oncogene 23, 546-553. doi: 10.1038/sj.onc.1207098
    • (2004) Oncogene , vol.23 , pp. 546-553
    • Richardson, C.1    Stark, J.M.2    Ommundsen, M.3    Jasin, M.4
  • 125
    • 84861460657 scopus 로고    scopus 로고
    • Clustered mutations in yeast and in human cancers can arise from damaged long single-strand DNA regions
    • doi: 10.1016/j.molcel.2012.03.030
    • Roberts, S. A., Sterling, J., Thompson, C., Harris, S., Mav, D., Shah, R., et al. (2012). Clustered mutations in yeast and in human cancers can arise from damaged long single-strand DNA regions. Mol. Cell . 46, 424-435. doi: 10.1016/j.molcel.2012.03.030
    • (2012) Mol. Cell. , vol.46 , pp. 424-435
    • Roberts, S.A.1    Sterling, J.2    Thompson, C.3    Harris, S.4    Mav, D.5    Shah, R.6
  • 126
    • 84875579247 scopus 로고    scopus 로고
    • The RAD51 paralogs ensure cellular protection against mitotic defects and aneuploidy
    • doi: 10.1242/jcs.114595
    • Rodrigue, A., Coulombe, Y., Jacquet, K., Gagne, J. P., Roques, C., Gobeil, S., et al. (2013). The RAD51 paralogs ensure cellular protection against mitotic defects and aneuploidy. J. Cell Sci . 126, 348-359. doi: 10.1242/jcs.114595
    • (2013) J. Cell Sci. , vol.126 , pp. 348-359
    • Rodrigue, A.1    Coulombe, Y.2    Jacquet, K.3    Gagne, J.P.4    Roques, C.5    Gobeil, S.6
  • 127
    • 3242887420 scopus 로고    scopus 로고
    • The role of the non-homologous end-joining pathway in lymphocyte development
    • doi: 10.1111/j.0105-2896.2004.00165.x
    • Rooney, S., Chaudhuri, J., and Alt, F. W. (2004). The role of the non-homologous end-joining pathway in lymphocyte development. Immunol. Rev . 200, 115-131. doi: 10.1111/j.0105-2896.2004.00165.x
    • (2004) Immunol. Rev. , vol.200 , pp. 115-131
    • Rooney, S.1    Chaudhuri, J.2    Alt, F.W.3
  • 128
    • 43249128930 scopus 로고    scopus 로고
    • Mus81 is essential for sister chromatid recombination at broken replication forks
    • doi: 10.1038/emboj.2008.65
    • Roseaulin, L., Yamada, Y., Tsutsui, Y., Russell, P., Iwasaki, H., and Arcangioli, B. (2008). Mus81 is essential for sister chromatid recombination at broken replication forks. EMBO J . 27, 1378-1387. doi: 10.1038/emboj.2008.65
    • (2008) EMBO J. , vol.27 , pp. 1378-1387
    • Roseaulin, L.1    Yamada, Y.2    Tsutsui, Y.3    Russell, P.4    Iwasaki, H.5    Arcangioli, B.6
  • 129
    • 0027941501 scopus 로고
    • Adaptive mutation by deletions in small mononucleotide repeats
    • doi: 10.1126/science.8023163
    • Rosenberg, S. M., Longerich, S., Gee, P., and Harris, R. S. (1994). Adaptive mutation by deletions in small mononucleotide repeats. Science 265, 405-407. doi: 10.1126/science.8023163
    • (1994) Science , vol.265 , pp. 405-407
    • Rosenberg, S.M.1    Longerich, S.2    Gee, P.3    Harris, R.S.4
  • 130
    • 84866279660 scopus 로고    scopus 로고
    • Stress-induced mutation via DNA breaks in Escherichia coli: a molecular mechanism with implications for evolution and medicine
    • doi: 10.1002/bies.201200050
    • Rosenberg, S. M., Shee, C., Frisch, R. L., and Hastings, P. J. (2012). Stress-induced mutation via DNA breaks in Escherichia coli: a molecular mechanism with implications for evolution and medicine. Bioessays 34, 885-892. doi: 10.1002/bies.201200050
    • (2012) Bioessays , vol.34 , pp. 885-892
    • Rosenberg, S.M.1    Shee, C.2    Frisch, R.L.3    Hastings, P.J.4
  • 131
    • 0037884963 scopus 로고    scopus 로고
    • Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses
    • doi: 10.1073/pnas.0830918100
    • Rothkamm, K., and Lobrich, M. (2003). Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses. Proc. Natl. Acad. Sci. U.S.A . 100, 5057-5062. doi: 10.1073/pnas.0830918100
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 5057-5062
    • Rothkamm, K.1    Lobrich, M.2
  • 132
    • 70350457512 scopus 로고    scopus 로고
    • Chromosomal translocations caused by either pol32-dependent or pol32-independent triparental break-induced replication
    • doi: 10.1128/MCB.00256-09
    • Ruiz, J. F., Gomez-Gonzalez, B., and Aguilera, A. (2009). Chromosomal translocations caused by either pol32-dependent or pol32-independent triparental break-induced replication. Mol. Cell. Biol . 29, 5441-5454. doi: 10.1128/MCB.00256-09
    • (2009) Mol. Cell. Biol. , vol.29 , pp. 5441-5454
    • Ruiz, J.F.1    Gomez-Gonzalez, B.2    Aguilera, A.3
  • 133
    • 84885843906 scopus 로고    scopus 로고
    • Migrating bubble during break-induced replication drives conservative DNA synthesis
    • doi: 10.1038/nature12584
    • Saini, N., Ramakrishnan, S., Elango, R., Ayyar, S., Zhang, Y., Deem, A., et al. (2013). Migrating bubble during break-induced replication drives conservative DNA synthesis. Nature 502, 389-392. doi: 10.1038/nature12584
    • (2013) Nature , vol.502 , pp. 389-392
    • Saini, N.1    Ramakrishnan, S.2    Elango, R.3    Ayyar, S.4    Zhang, Y.5    Deem, A.6
  • 134
    • 0035898405 scopus 로고    scopus 로고
    • Characterization of homologous recombination induced by replication inhibition in mammalian cells
    • doi: 10.1093/emboj/20.14.3861
    • Saintigny, Y., Delacote, F., Vares, G., Petitot, F., Lambert, S., Averbeck, D., et al. (2001). Characterization of homologous recombination induced by replication inhibition in mammalian cells. EMBO J . 20, 3861-3870. doi: 10.1093/emboj/20.14.3861
    • (2001) EMBO J. , vol.20 , pp. 3861-3870
    • Saintigny, Y.1    Delacote, F.2    Vares, G.3    Petitot, F.4    Lambert, S.5    Averbeck, D.6
  • 135
    • 79955799175 scopus 로고    scopus 로고
    • Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11
    • doi: 10.1016/j.cell.2011.03.041
    • Schlacher, K., Christ, N., Siaud, N., Egashira, A., Wu, H., and Jasin, M. (2011). Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11. Cell 145, 529-542. doi: 10.1016/j.cell.2011.03.041
    • (2011) Cell , vol.145 , pp. 529-542
    • Schlacher, K.1    Christ, N.2    Siaud, N.3    Egashira, A.4    Wu, H.5    Jasin, M.6
  • 136
    • 33745872612 scopus 로고    scopus 로고
    • Control of translocations between highly diverged genes by Sgs1, the Saccharomyces cerevisiae homolog of the Bloom's syndrome protein
    • doi: 10.1128/MCB.00161-06
    • Schmidt, K. H., Wu, J., and Kolodner, R. D. (2006). Control of translocations between highly diverged genes by Sgs1, the Saccharomyces cerevisiae homolog of the Bloom's syndrome protein. Mol. Cell. Biol . 26, 5406-5420. doi: 10.1128/MCB.00161-06
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 5406-5420
    • Schmidt, K.H.1    Wu, J.2    Kolodner, R.D.3
  • 137
    • 0032582794 scopus 로고    scopus 로고
    • RuvAB acts at arrested replication forks
    • doi: 10.1016/S0092-8674(00)81772-9
    • Seigneur, M., Bidnenko, V., Ehrlich, S. D., and Michel, B. (1998). RuvAB acts at arrested replication forks. Cell 95, 419-430. doi: 10.1016/S0092-8674(00)81772-9
    • (1998) Cell , vol.95 , pp. 419-430
    • Seigneur, M.1    Bidnenko, V.2    Ehrlich, S.D.3    Michel, B.4
  • 138
    • 80051961878 scopus 로고    scopus 로고
    • Impact of a stress-inducible switch to mutagenic repair of DNA breaks on mutation in Escherichia coli
    • doi: 10.1073/pnas.1104681108
    • Shee, C., Gibson, J. L., Darrow, M. C., Gonzalez, C., and Rosenberg, S. M. (2011). Impact of a stress-inducible switch to mutagenic repair of DNA breaks on mutation in Escherichia coli. Proc. Natl. Acad. Sci. U.S.A . 108, 13659-13664. doi: 10.1073/pnas.1104681108
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 13659-13664
    • Shee, C.1    Gibson, J.L.2    Darrow, M.C.3    Gonzalez, C.4    Rosenberg, S.M.5
  • 139
    • 33749993417 scopus 로고    scopus 로고
    • The consensus coding sequences of human breast and colorectal cancers
    • doi: 10.1126/science.1133427
    • Sjoblom, T., Jones, S., Wood, L. D., Parsons, D. W., Lin, J., Barber, T. D., et al. (2006). The consensus coding sequences of human breast and colorectal cancers. Science 314, 268-274. doi: 10.1126/science.1133427
    • (2006) Science , vol.314 , pp. 268-274
    • Sjoblom, T.1    Jones, S.2    Wood, L.D.3    Parsons, D.W.4    Lin, J.5    Barber, T.D.6
  • 140
    • 0034760095 scopus 로고    scopus 로고
    • BCR/ABL regulates mammalian RecA homologs, resulting in drug resistance
    • doi: 10.1016/S1097-2765(01)00357-4
    • Slupianek, A., Schmutte, C., Tombline, G., Nieborowska-Skorska, M., Hoser, G., Nowicki, M. O., et al. (2001). BCR/ABL regulates mammalian RecA homologs, resulting in drug resistance. Mol. Cell . 8, 795-806. doi: 10.1016/S1097-2765(01)00357-4
    • (2001) Mol. Cell. , vol.8 , pp. 795-806
    • Slupianek, A.1    Schmutte, C.2    Tombline, G.3    Nieborowska-Skorska, M.4    Hoser, G.5    Nowicki, M.O.6
  • 141
    • 76349094670 scopus 로고    scopus 로고
    • APOBEC3 proteins mediate the clearance of foreign DNA from human cells
    • doi: 10.1038/nsmb.1744
    • Stenglein, M. D., Burns, M. B., Li, M., Lengyel, J., and Harris, R. S. (2010). APOBEC3 proteins mediate the clearance of foreign DNA from human cells. Nat. Struct. Mol. Biol . 17, 222-229. doi: 10.1038/nsmb.1744
    • (2010) Nat. Struct. Mol. Biol. , vol.17 , pp. 222-229
    • Stenglein, M.D.1    Burns, M.B.2    Li, M.3    Lengyel, J.4    Harris, R.S.5
  • 142
    • 78650959663 scopus 로고    scopus 로고
    • Massive genomic rearrangement acquired in a single catastrophic event during cancer development
    • doi: 10.1016/j.cell.2010.11.055
    • Stephens, P. J., Greenman, C. D., Fu, B., Yang, F., Bignell, G. R., Mudie, L. J., et al. (2011). Massive genomic rearrangement acquired in a single catastrophic event during cancer development. Cell 144, 27-40. doi: 10.1016/j.cell.2010.11.055
    • (2011) Cell , vol.144 , pp. 27-40
    • Stephens, P.J.1    Greenman, C.D.2    Fu, B.3    Yang, F.4    Bignell, G.R.5    Mudie, L.J.6
  • 143
    • 84861576201 scopus 로고    scopus 로고
    • The landscape of cancer genes and mutational processes in breast cancer
    • doi: 10.1038/nature11017
    • Stephens, P. J., Tarpey, P. S., Davies, H., Van Loo, P., Greenman, C., Wedge, D. C., et al. (2012). The landscape of cancer genes and mutational processes in breast cancer. Nature 486, 400-404. doi: 10.1038/nature11017
    • (2012) Nature , vol.486 , pp. 400-404
    • Stephens, P.J.1    Tarpey, P.S.2    Davies, H.3    Van Loo, P.4    Greenman, C.5    Wedge, D.C.6
  • 144
    • 48349115919 scopus 로고    scopus 로고
    • Antigenic variation in Trypanosoma brucei: joining the DOTs.
    • doi: 10.1371/journal.pbio.0060185
    • Stockdale, C., Swiderski, M. R., Barry, J. D., and McCulloch, R. (2008). Antigenic variation in Trypanosoma brucei: joining the DOTs. PLoS Biol . 6:e185. doi: 10.1371/journal.pbio.0060185
    • (2008) PLoS Biol. , vol.6
    • Stockdale, C.1    Swiderski, M.R.2    Barry, J.D.3    McCulloch, R.4
  • 145
    • 80052158097 scopus 로고    scopus 로고
    • The mutational landscape of head and neck squamous cell carcinoma
    • doi: 10.1126/science.1208130
    • Stransky, N., Egloff, A. M., Tward, A. D., Kostic, A. D., Cibulskis, K., Sivachenko, A., et al. (2011). The mutational landscape of head and neck squamous cell carcinoma. Science 333, 1157-1160. doi: 10.1126/science.1208130
    • (2011) Science , vol.333 , pp. 1157-1160
    • Stransky, N.1    Egloff, A.M.2    Tward, A.D.3    Kostic, A.D.4    Cibulskis, K.5    Sivachenko, A.6
  • 146
    • 0029024834 scopus 로고
    • DNA synthesis errors associated with double-strand-break repair.
    • Strathern, J. N., Shafer, B. K., and McGill, C. B. (1995). DNA synthesis errors associated with double-strand-break repair. Genetics 140, 965-972.
    • (1995) Genetics , vol.140 , pp. 965-972
    • Strathern, J.N.1    Shafer, B.K.2    McGill, C.B.3
  • 147
    • 64749094310 scopus 로고    scopus 로고
    • The cancer genome
    • doi: 10.1038/nature07943
    • Stratton, M. R., Campbell, P. J., and Futreal, P. A. (2009). The cancer genome. Nature 458, 719-724. doi: 10.1038/nature07943
    • (2009) Nature , vol.458 , pp. 719-724
    • Stratton, M.R.1    Campbell, P.J.2    Futreal, P.A.3
  • 148
    • 0034742120 scopus 로고    scopus 로고
    • AKT1/PKBalpha kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic transformation in NIH3T3 cells
    • doi: 10.1016/S0002-9440(10)61714-2
    • Sun, M., Wang, G., Paciga, J. E., Feldman, R. I., Yuan, Z. Q., Ma, X. L., et al. (2001). AKT1/PKBalpha kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic transformation in NIH3T3 cells. Am. J. Pathol . 159, 431-437. doi: 10.1016/S0002-9440(10)61714-2
    • (2001) Am. J. Pathol. , vol.159 , pp. 431-437
    • Sun, M.1    Wang, G.2    Paciga, J.E.3    Feldman, R.I.4    Yuan, Z.Q.5    Ma, X.L.6
  • 149
    • 79953194132 scopus 로고    scopus 로고
    • Somatic hypermutation of human mitochondrial and nuclear DNA by APOBEC3 cytidine deaminases, a pathway for DNA catabolism
    • doi: 10.1073/pnas.1009687108
    • Suspene, R., Aynaud, M. M., Guetard, D., Henry, M., Eckhoff, G., Marchio, A., et al. (2011). Somatic hypermutation of human mitochondrial and nuclear DNA by APOBEC3 cytidine deaminases, a pathway for DNA catabolism. Proc. Natl. Acad. Sci. U.S.A . 108, 4858-4863. doi: 10.1073/pnas.1009687108
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 4858-4863
    • Suspene, R.1    Aynaud, M.M.2    Guetard, D.3    Henry, M.4    Eckhoff, G.5    Marchio, A.6
  • 150
    • 0035083172 scopus 로고    scopus 로고
    • Chromosome instability and defective recombinational repair in knockout mutants of the five Rad51 paralogs
    • doi: 10.1128/MCB.21.8.2858-2866.2001
    • Takata, M., Sasaki, M. S., Tachiiri, S., Fukushima, T., Sonoda, E., Schild, D., et al. (2001). Chromosome instability and defective recombinational repair in knockout mutants of the five Rad51 paralogs. Mol. Cell. Biol . 21, 2858-2866. doi: 10.1128/MCB.21.8.2858-2866.2001
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 2858-2866
    • Takata, M.1    Sasaki, M.S.2    Tachiiri, S.3    Fukushima, T.4    Sonoda, E.5    Schild, D.6
  • 151
    • 3242889151 scopus 로고    scopus 로고
    • Ataxia-telangiectasia-like disorder (ATLD)-its clinical presentation and molecular basis
    • doi: 10.1016/j.dnarep.2004.04.009
    • Taylor, A. M., Groom, A., and Byrd, P. J. (2004). Ataxia-telangiectasia-like disorder (ATLD)-its clinical presentation and molecular basis. DNA Repair (Amst.) 3, 1219-1225. doi: 10.1016/j.dnarep.2004.04.009
    • (2004) DNA Repair (Amst.) , vol.3 , pp. 1219-1225
    • Taylor, A.M.1    Groom, A.2    Byrd, P.J.3
  • 152
    • 84879061509 scopus 로고    scopus 로고
    • DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis.
    • doi: 10.7554/eLife.00534
    • Taylor, B. J., Nik-Zainal, S., Wu, Y. L., Stebbings, L. A., Raine, K., Campbell, P. J., et al. (2013). DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis. Elife 2:e00534. doi: 10.7554/eLife.00534
    • (2013) Elife , vol.2
    • Taylor, B.J.1    Nik-Zainal, S.2    Wu, Y.L.3    Stebbings, L.A.4    Raine, K.5    Campbell, P.J.6
  • 153
    • 83555176004 scopus 로고    scopus 로고
    • Nuclear envelope defects impede a proper response to micronuclear DNA lesions
    • doi: 10.1016/j.mrfmmm.2011.09.003
    • Terradas, M., Martin, M., Hernandez, L., Tusell, L., and Genesca, A. (2012). Nuclear envelope defects impede a proper response to micronuclear DNA lesions. Mutat. Res . 729, 35-40. doi: 10.1016/j.mrfmmm.2011.09.003
    • (2012) Mutat. Res. , vol.729 , pp. 35-40
    • Terradas, M.1    Martin, M.2    Hernandez, L.3    Tusell, L.4    Genesca, A.5
  • 154
    • 70149107457 scopus 로고    scopus 로고
    • DNA lesions sequestered in micronuclei induce a local defective-damage response
    • doi: 10.1016/j.dnarep.2009.07.004
    • Terradas, M., Martin, M., Tusell, L., and Genesca, A. (2009). DNA lesions sequestered in micronuclei induce a local defective-damage response. DNA Repair (Amst.) 8, 1225-1234. doi: 10.1016/j.dnarep.2009.07.004
    • (2009) DNA Repair (Amst.) , vol.8 , pp. 1225-1234
    • Terradas, M.1    Martin, M.2    Tusell, L.3    Genesca, A.4
  • 155
    • 0035796042 scopus 로고    scopus 로고
    • Homologous recombinational repair of DNA ensures mammalian chromosome stability
    • doi: 10.1016/S0027-5107(01)00115-4
    • Thompson, L. H., and Schild, D. (2001). Homologous recombinational repair of DNA ensures mammalian chromosome stability. Mutat. Res . 477, 131-153. doi: 10.1016/S0027-5107(01)00115-4
    • (2001) Mutat. Res. , vol.477 , pp. 131-153
    • Thompson, L.H.1    Schild, D.2
  • 156
    • 34249935010 scopus 로고    scopus 로고
    • Maintenance of fork integrity at damaged DNA and natural pause sites
    • doi: 10.1016/j.dnarep.2007.02.004
    • Tourriere, H., and Pasero, P. (2007). Maintenance of fork integrity at damaged DNA and natural pause sites. DNA Repair (Amst.) 6, 900-913. doi: 10.1016/j.dnarep.2007.02.004
    • (2007) DNA Repair (Amst.) , vol.6 , pp. 900-913
    • Tourriere, H.1    Pasero, P.2
  • 157
    • 0037099669 scopus 로고    scopus 로고
    • The fragile histidine triad/common chromosome fragile site 3B locus and repair-deficient cancers
    • Turner, B. C., Ottey, M., Zimonjic, D. B., Potoczek, M., Hauck, W. W., Pequignot, E., et al. (2002). The fragile histidine triad/common chromosome fragile site 3B locus and repair-deficient cancers. Cancer Res . 62, 4054-4060.
    • (2002) Cancer Res. , vol.62 , pp. 4054-4060
    • Turner, B.C.1    Ottey, M.2    Zimonjic, D.B.3    Potoczek, M.4    Hauck, W.W.5    Pequignot, E.6
  • 158
    • 0032526320 scopus 로고    scopus 로고
    • Overexpression of Rad51 protein stimulates homologous recombination and increases resistance of mammalian cells to ionizing radiation
    • doi: 10.1093/nar/26.12.2859
    • Vispé, S., Cazaux, C., Lesca, C., and Defais, M. (1998). Overexpression of Rad51 protein stimulates homologous recombination and increases resistance of mammalian cells to ionizing radiation. Nucleic Acids Res . 26, 2859-2864. doi: 10.1093/nar/26.12.2859
    • (1998) Nucleic Acids Res. , vol.26 , pp. 2859-2864
    • Vispé, S.1    Cazaux, C.2    Lesca, C.3    Defais, M.4
  • 159
    • 81055126264 scopus 로고    scopus 로고
    • Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing
    • doi: 10.1073/pnas.1115052108
    • Walsh, T., Casadei, S., Lee, M. K., Pennil, C. C., Nord, A. S., Thornton, A. M., et al. (2011). Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing. Proc. Natl. Acad. Sci. U.S.A . 108, 18032-18037. doi: 10.1073/pnas.1115052108
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 18032-18037
    • Walsh, T.1    Casadei, S.2    Lee, M.K.3    Pennil, C.C.4    Nord, A.S.5    Thornton, A.M.6
  • 160
    • 33846850422 scopus 로고    scopus 로고
    • Ten genes for inherited breast cancer
    • doi: 10.1016/j.ccr.2007.01.010
    • Walsh, T., and King, M. C. (2007). Ten genes for inherited breast cancer. Cancer Cell . 11, 103-105. doi: 10.1016/j.ccr.2007.01.010
    • (2007) Cancer Cell. , vol.11 , pp. 103-105
    • Walsh, T.1    King, M.C.2
  • 161
    • 84892616274 scopus 로고    scopus 로고
    • Spontaneous slow replication fork progression elicits mitosis alterations in homologous recombination-deficient mammalian cells
    • doi: 10.1073/pnas.1311520111
    • Wilhelm, T., Magdalou, I., Barascu, A., Techer, H., Debatisse, M., and Lopez, B. S. (2014). Spontaneous slow replication fork progression elicits mitosis alterations in homologous recombination-deficient mammalian cells. Proc. Natl. Acad. Sci. U.S.A . 111, 763-768. doi: 10.1073/pnas.1311520111
    • (2014) Proc. Natl. Acad. Sci. U.S.A. , vol.111 , pp. 763-768
    • Wilhelm, T.1    Magdalou, I.2    Barascu, A.3    Techer, H.4    Debatisse, M.5    Lopez, B.S.6
  • 162
    • 84885866032 scopus 로고    scopus 로고
    • Pif1 helicase and Poldelta promote recombination-coupled DNA synthesis via bubble migration
    • doi: 10.1038/nature12585
    • Wilson, M. A., Kwon, Y., Xu, Y., Chung, W. H., Chi, P., Niu, H., et al. (2013). Pif1 helicase and Poldelta promote recombination-coupled DNA synthesis via bubble migration. Nature 502, 393-396. doi: 10.1038/nature12585
    • (2013) Nature , vol.502 , pp. 393-396
    • Wilson, M.A.1    Kwon, Y.2    Xu, Y.3    Chung, W.H.4    Chi, P.5    Niu, H.6
  • 163
    • 53349096680 scopus 로고    scopus 로고
    • Phase and antigenic variation mediated by genome modifications
    • doi: 10.1007/s10482-008-9267-6
    • Wisniewski-Dye, F., and Vial, L. (2008). Phase and antigenic variation mediated by genome modifications. Antonie Van Leeuwenhoek . 94, 493-515. doi: 10.1007/s10482-008-9267-6
    • (2008) Antonie Van Leeuwenhoek. , vol.94 , pp. 493-515
    • Wisniewski-Dye, F.1    Vial, L.2
  • 164
    • 0029159759 scopus 로고
    • Apolipoprotein B mRNA-editing protein induces hepatocellular carcinoma and dysplasia in transgenic animals
    • doi: 10.1073/pnas.92.18.8483
    • Yamanaka, S., Balestra, M. E., Ferrell, L. D., Fan, J., Arnold, K. S., Taylor, S., et al. (1995). Apolipoprotein B mRNA-editing protein induces hepatocellular carcinoma and dysplasia in transgenic animals. Proc. Natl. Acad. Sci. U.S.A . 92, 8483-8487. doi: 10.1073/pnas.92.18.8483
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 8483-8487
    • Yamanaka, S.1    Balestra, M.E.2    Ferrell, L.D.3    Fan, J.4    Arnold, K.S.5    Taylor, S.6
  • 165
    • 33645532245 scopus 로고    scopus 로고
    • DNA damage-induced protein 14-3-3 sigma inhibits protein kinase B/Akt activation and suppresses Akt-activated cancer
    • doi: 10.1158/0008-5472.CAN-05-3620
    • Yang, H., Wen, Y. Y., Zhao, R., Lin, Y. L., Fournier, K., Yang, H. Y., et al. (2006). DNA damage-induced protein 14-3-3 sigma inhibits protein kinase B/Akt activation and suppresses Akt-activated cancer. Cancer Res . 66, 3096-3105. doi: 10.1158/0008-5472.CAN-05-3620
    • (2006) Cancer Res. , vol.66 , pp. 3096-3105
    • Yang, H.1    Wen, Y.Y.2    Zhao, R.3    Lin, Y.L.4    Fournier, K.5    Yang, H.Y.6
  • 166
    • 57149094856 scopus 로고    scopus 로고
    • Hypermutability of damaged single-strand DNA formed at double-strand breaks and uncapped telomeres in yeast Saccharomyces cerevisiae.
    • doi: 10.1371/journal.pgen.1000264
    • Yang, Y., Sterling, J., Storici, F., Resnick, M. A., and Gordenin, D. A. (2008). Hypermutability of damaged single-strand DNA formed at double-strand breaks and uncapped telomeres in yeast Saccharomyces cerevisiae. PLoS Genet . 4:e1000264. doi: 10.1371/journal.pgen.1000264
    • (2008) PLoS Genet. , vol.4
    • Yang, Y.1    Sterling, J.2    Storici, F.3    Resnick, M.A.4    Gordenin, D.A.5
  • 167
    • 78650996873 scopus 로고    scopus 로고
    • CENP-B preserves genome integrity at replication forks paused by retrotransposon LTR
    • doi: 10.1038/nature09608
    • Zaratiegui, M., Vaughn, M. W., Irvine, D. V., Goto, D., Watt, S., Bahler, J., et al. (2011). CENP-B preserves genome integrity at replication forks paused by retrotransposon LTR. Nature 469, 112-115. doi: 10.1038/nature09608
    • (2011) Nature , vol.469 , pp. 112-115
    • Zaratiegui, M.1    Vaughn, M.W.2    Irvine, D.V.3    Goto, D.4    Watt, S.5    Bahler, J.6
  • 168
    • 67649878596 scopus 로고    scopus 로고
    • The DNA replication FoSTeS/MMBIR mechanism can generate genomic, genic and exonic complex rearrangements in humans
    • doi: 10.1038/ng.399
    • Zhang, F., Khajavi, M., Connolly, A. M., Towne, C. F., Batish, S. D., and Lupski, J. R. (2009). The DNA replication FoSTeS/MMBIR mechanism can generate genomic, genic and exonic complex rearrangements in humans. Nat. Genet . 41, 849-853. doi: 10.1038/ng.399
    • (2009) Nat. Genet. , vol.41 , pp. 849-853
    • Zhang, F.1    Khajavi, M.2    Connolly, A.M.3    Towne, C.F.4    Batish, S.D.5    Lupski, J.R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.