-
1
-
-
0034643838
-
Prevalence of Parkinson's disease in Europe: A collaborative study of population-based cohorts
-
de Rijk, M. C.; Launer, L. J.; Berger, K.; Breteler, M. M.; Dartigues, J. F.; Baldereschi, M., et al. Prevalence of Parkinson's disease in Europe: a collaborative study of population-based cohorts. Neurologic Diseases in the Elderly Research Group. Neurology 54:S21-S23; 2000. (Pubitemid 30390601)
-
(2000)
Neurology
, vol.54
, Issue.SUPPL. 5
-
-
De Rijk, M.C.1
Launer, L.J.2
Berger, K.3
Breteler, M.M.B.4
Dartigues, J.-F.5
Baldereschi, M.6
Fratiglioni, L.7
Lobo, A.8
Martinez-Lage, J.9
Trenkwalder, C.10
Hofman, A.11
-
3
-
-
33748951973
-
Parkinson's disease and family history
-
DOI 10.1016/j.parkreldis.2006.03.002, PII S1353802006000708
-
Sellbach, A. N.; Boyle, R. S.; Silburn, P. A.; Mellick, G. D. Parkinson's disease and family history. Parkinsonism Relat. Disord. 12: 399-409; 2006. (Pubitemid 44430174)
-
(2006)
Parkinsonism and Related Disorders
, vol.12
, Issue.7
, pp. 399-409
-
-
Sellbach, A.N.1
Boyle, R.S.2
Silburn, P.A.3
Mellick, G.D.4
-
4
-
-
33645116252
-
Genetics of Parkinson disease: Paradigm shifts and future prospects
-
Farrer, M. J. Genetics of Parkinson disease: paradigm shifts and future prospects. Nat. Rev. Genet. 7: 306-318; 2006.
-
(2006)
Nat. Rev. Genet
, vol.7
, pp. 306-318
-
-
Farrer, M.J.1
-
5
-
-
33745919520
-
Epidemiology of Parkinson's disease
-
DOI 10.1016/S1474-4422(06)70471-9, PII S1474442206704719
-
de Lau, L. M.; Breteler, M. M. Epidemiology of Parkinson's disease. Lancet Neurol. 5: 525-535; 2006. (Pubitemid 44262284)
-
(2006)
Lancet Neurology
, vol.5
, Issue.6
, pp. 525-535
-
-
De Lau, L.M.1
Breteler, M.M.2
-
6
-
-
79952164540
-
Mitochondrial dysfunction in Parkinson's disease: Pathogenesis and neuroprotection
-
Mounsey, R. B.; Teismann, P. Mitochondrial dysfunction in Parkinson's disease: pathogenesis and neuroprotection. Parkinsons Dis 617472: 2010; 2011.
-
(2010)
Parkinsons Dis
, vol.2011
, pp. 617472
-
-
Mounsey, R.B.1
Teismann, P.2
-
7
-
-
67449104699
-
Etiology and pathogenesis of Parkinson disease
-
v.
-
Schapira, A. H. Etiology and pathogenesis of Parkinson disease. Neurol. Clin. 27: 583-603; 2009. v.
-
(2009)
Neurol. Clin
, vol.27
, pp. 583-603
-
-
Schapira A., .H.1
-
8
-
-
0025254401
-
Mitochondrial complex i deficiency in Parkinson's disease
-
Schapira, A. H.; Cooper, J. M.; Dexter, D.; Clark, J. B.; Jenner, P.; Marsden, C. D. Mitochondrial complex I deficiency in Parkinson's disease. J. Neurochem. 54: 823-827; 1990.
-
(1990)
J. Neurochem
, vol.54
, pp. 823-827
-
-
Schapira, A.H.1
Cooper, J.M.2
Dexter, D.3
Clark, J.B.4
Jenner, P.5
Marsden, C.D.6
-
9
-
-
0024390719
-
Mitochondrial complex I deficiency in Parkinson's disease
-
Schapira, A. H.; Cooper, J. M.; Dexter, D.; Jenner, P.; Clark, J. B.; Marsden, C. D. Mitochondrial complex I deficiency in Parkinson's disease. Lancet 1: 1269; 1989. (Pubitemid 19140359)
-
(1989)
Lancet
, vol.1
, Issue.8649
, pp. 1269
-
-
Schapira, A.H.V.1
Cooper, J.M.2
Dexter, D.3
Jenner, P.4
Clark, J.B.5
Marsden, C.D.6
-
10
-
-
0026704075
-
Alterations in levels of iron, ferritin, and other trace metals in neurodegenerative diseases affecting the basal ganglia
-
The Royal Kings and Queens Parkinson's Disease Research Group
-
Dexter, D. T.; Jenner, P.; Schapira, A. H.; Marsden, C. D. Alterations in levels of iron, ferritin, and other trace metals in neurodegenerative diseases affecting the basal ganglia. The Royal Kings and Queens Parkinson's Disease Research Group. Ann. Neurol 32(Suppl):S94-100; 1992.
-
(1992)
Ann. Neurol
, vol.32
, Issue.SUPPL.
-
-
Dexter, D.T.1
Jenner, P.2
Schapira, A.H.3
Marsden, C.D.4
-
11
-
-
0029741621
-
Oxidative stress and Parkinson's disease
-
Owen, A. D.; Schapira, A. H.; Jenner, P.; Marsden, C. D. Oxidative stress and Parkinson's disease. Ann. N. Y. Acad. Sci. 786: 217-223; 1996. (Pubitemid 26273166)
-
(1996)
Annals of the New York Academy of Sciences
, vol.786
, pp. 217-223
-
-
Owen, A.D.1
Schapira, A.H.V.2
Jenner, P.3
Marsden, C.D.4
-
12
-
-
0026548217
-
Quantitation of a mitochondrial DNA deletion in Parkinson's disease
-
Mann, V. M.; Cooper, J. M.; Schapira, A. H. Quantitation of a mitochondrial DNA deletion in Parkinson's disease. FEBS Lett 299: 218-222; 1992.
-
(1992)
FEBS Lett
, vol.299
, pp. 218-222
-
-
Mann, V.M.1
Cooper, J.M.2
Schapira, A.H.3
-
13
-
-
0028924168
-
Oxidative stress in Parkinson's disease
-
Schapira, A. H. Oxidative stress in Parkinson's disease. Neuropathol. Appl. Neurobiol. 21: 3-9; 1995.
-
(1995)
Neuropathol. Appl. Neurobiol
, vol.21
, pp. 3-9
-
-
Schapira, A.H.1
-
14
-
-
0032507983
-
Mitochondrial function, GSH and iron in neurodegeneration and Lewy body diseases
-
DOI 10.1016/S0022-510X(98)00095-1, PII S0022510X98000951
-
Gu, M.; Owen, A. D.; Toffa, S. E.; Cooper, J. M.; Dexter, D. T.; Jenner, P., et al. Mitochondrial function, GSH and iron in neurodegeneration and Lewy body diseases. J. Neurol. Sci. 158: 24-29; 1998. (Pubitemid 28277530)
-
(1998)
Journal of the Neurological Sciences
, vol.158
, Issue.1
, pp. 24-29
-
-
Gu, M.1
Owen, A.D.2
Toffa, S.E.K.3
Cooper, J.M.4
Dexter, D.T.5
Jenner, P.6
Marsden, C.D.7
Schapira, A.H.V.8
-
15
-
-
79251514977
-
Challenges to the development of disease-modifying therapies in Parkinson's disease
-
Schapira, A. H. Challenges to the development of disease-modifying therapies in Parkinson's disease. Eur. J. Neurol 18(Suppl. 1): 16-21; 2011.
-
(2011)
Eur. J. Neurol
, vol.18
, Issue.SUPPL. 1
, pp. 16-21
-
-
Schapira, A.H.1
-
16
-
-
0141705360
-
Mitochondrial dysfunction and reactive oxygen species in excitotoxicity and apoptosis: Implications for the pathogenesis of neurodegenerative diseases
-
DOI 10.1023/A:1025682611389
-
Rego, A. C.; Oliveira, C. R. Mitochondrial dysfunction and reactive oxygen species in excitotoxicity and apoptosis: implications for the pathogenesis of neurodegenerative diseases. Neurochem. Res 28: 1563-1574; 2003. (Pubitemid 37193539)
-
(2003)
Neurochemical Research
, vol.28
, Issue.10
, pp. 1563-1574
-
-
Rego, A.C.1
Oliveira, C.R.2
-
17
-
-
71849092190
-
Neuropathological assessment of Parkinson's disease: Refining the diagnostic criteria
-
Dickson, D. W.; Braak, H.; Duda, J. E.; Duyckaerts, C.; Gasser, T.; Halliday, G. M., et al. Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria. Lancet Neurol. 8: 115 0 -11 57 ; 2 0 0 9 .
-
(2009)
Lancet Neurol
, vol.8
, pp. 1150-1157
-
-
Dickson, D.W.1
Braak, H.2
Duda, J.E.3
Duyckaerts, C.4
Gasser, T.5
Halliday, G.M.6
-
18
-
-
79957586330
-
Milestones in Parkinson's disease - Clinical and pathologic features
-
Halliday, G.; Lees, A.; Stern, M. Milestones in Parkinson's disease - clinical and pathologic features. Mov. Disord 26: 1015-1021; 2011.
-
(2011)
Mov. Disord
, vol.26
, pp. 1015-1021
-
-
Halliday, G.1
Lees, A.2
Stern, M.3
-
19
-
-
0025954066
-
Ageing and parkinson's disease: Substantia nigra regional selectivity
-
Fearnley, J. M.; Lees, A. J. Ageing and Parkinson's disease: substantia nigra regional selectivity. Brain 114(Pt 5): 2283-2301; 1991.
-
(1991)
Brain
, vol.114
, Issue.PART 5
, pp. 2283-2301
-
-
Fearnley, J.M.1
Lees, A.J.2
-
20
-
-
84860686110
-
Can parkinson's disease pathology be propagated from one neuron to another?
-
Dunning, C. J.; Reyes, J. F.; Steiner, J. A.; Brundin, P. Can Parkinson's disease pathology be propagated from one neuron to another? Prog. Neurobiol 97: 205-219; 2012.
-
(2012)
Prog. Neurobiol
, vol.97
, pp. 205-219
-
-
Dunning, C.J.1
Reyes, J.F.2
Steiner, J.A.3
Brundin, P.4
-
21
-
-
2542596183
-
Parkinson's disease
-
DOI 10.1016/S0140-6736(04)16305-8, PII S0140673604163058
-
Samii, A.; Nutt, J. G.; Ransom, B. R. Parkinson's disease. Lancet 363: 17 8 3 -1793; 2004. (Pubitemid 38698383)
-
(2004)
Lancet
, vol.363
, Issue.9423
, pp. 1783-1793
-
-
Samii, A.1
Nutt, J.G.2
Ransom, B.R.3
-
22
-
-
0036150971
-
The synucleins
-
George J.M. The synucleins. Genome Biol. 3:reviews3002; 2002.
-
(2002)
Genome Biol
, vol.3
-
-
George, J.M.1
-
23
-
-
41049097524
-
New insights into the pathology of Parkinson's disease: Does the peripheral autonomic system become central?
-
DOI 10.1111/j.1468-1331.2008.02057.x
-
Probst, A.; Bloch, A.; Tolnay, M. New insights into the pathology of Parkinson's disease: does the peripheral autonomic system become central? Eur. J. Neurol 15(Suppl. 1): 1-4; 2008. (Pubitemid 351421305)
-
(2008)
European Journal of Neurology
, vol.15
, Issue.SUPPL. 1
, pp. 1-4
-
-
Probst, A.1
Bloch, A.2
Tolnay, M.3
-
24
-
-
79957606041
-
Etiology and pathogenesis of Parkinson's disease
-
Schapira, A. H.; Jenner, P. Etiology and pathogenesis of Parkinson's disease. Mov. Disord 26: 1049-1055; 2011.
-
(2011)
Mov. Disord
, vol.26
, pp. 1049-1055
-
-
Schapira, A.H.1
Jenner, P.2
-
25
-
-
0000412998
-
Cohort analysis of parkinson's syndrome: Evidence for a single etiology related to subclinical infection about 1920
-
Poskanzer, D. C.; Schwab, R. S. Cohort analysis of Parkinson's syndrome: evidence for a single etiology related to subclinical infection about 1920. J. Chronic Dis 16: 961-973; 1963.
-
(1963)
J. Chronic Dis
, vol.16
, pp. 961-973
-
-
Poskanzer, D.C.1
Schwab, R.S.2
-
26
-
-
80054787664
-
What genetics tells us about the causes and mechanisms of parkinson's disease
-
Corti, O.; Lesage, S.; Brice, A. What genetics tells us about the causes and mechanisms of Parkinson's disease. Physiol. Rev 91: 116 1 -1218; 2011.
-
(2011)
Physiol. Rev
, vol.91
, pp. 1161-1218
-
-
Corti, O.1
Lesage, S.2
Brice, A.3
-
27
-
-
0035109494
-
Role of mitochondrial dysfunction and dopamine-dependent oxidative stress in amphetamine-induced toxicity
-
DOI 10.1002/1531-8249(200101)49:1<79::AID-ANA11>3.0.CO;2-D
-
Lotharius, J.; O'Malley, K. L. Role of mitochondrial dysfunction and dopamine-dependent oxidative stress in amphetamine-induced toxicity. Ann. Neurol 49: 79-89; 2001. (Pubitemid 32163008)
-
(2001)
Annals of Neurology
, vol.49
, Issue.1
, pp. 79-89
-
-
Lotharius, J.1
O'Malley, K.L.2
-
28
-
-
0027260872
-
+: Evidence for a new mechanism involving hydride transfer with xanthine oxidase, aldehyde dehydrogenase, and lipoamide dehydrogenase
-
DOI 10.1016/0891-5849(93)90056-Z
-
Klaidman, L. K.; Adams Jr. J. D.; Leung, A. C.; Kim, S. S.; Cadenas, E. Redox cycling of MPP+: evidence for a new mechanism involving hydride transfer with xanthine oxidase, aldehyde dehydrogenase, and lipoamide dehydro-genase. Free Radic. Biol. Med. 15: 169-179; 1993. (Pubitemid 23218819)
-
(1993)
Free Radical Biology and Medicine
, vol.15
, Issue.2
, pp. 169-179
-
-
Klaidman, L.K.1
Adams Jr., J.D.2
Leung, A.C.3
Kim, S.S.4
Cadenas, E.5
-
29
-
-
0020680904
-
Chronic parkinsonism in humans due to a product of meperidine-analog synthesis
-
Langston, J. W.; Ballard, P.; Tetrud, J. W.; Irwin, I. Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis. Science 219: 979-980; 1983. (Pubitemid 13189531)
-
(1983)
Science
, vol.219
, Issue.4587
, pp. 979-980
-
-
Langston, J.W.1
Ballard, P.2
Tetrud, J.W.3
Irwin, I.4
-
30
-
-
46749144187
-
Genomic investigation of alpha-synuclein multiplication and parkinsonism
-
DOI 10.1002/ana.21380
-
Ross, O. A.; Braithwaite, A. T.; Skipper, L. M.; Kachergus, J.; Hulihan, M. M.; Middleton, F. A., et al. Genomic investigation of a-synuclein multiplication and parkinsonism. Ann. Neurol. 63: 74 3 -750; 2008. (Pubitemid 351945533)
-
(2008)
Annals of Neurology
, vol.63
, Issue.6
, pp. 743-750
-
-
Ross, O.A.1
Braithwaite, A.T.2
Skipper, L.M.3
Kachergus, J.4
Hulihan, M.M.5
Middleton, F.A.6
Nishioka, K.7
Fuchs, J.8
Gasser, T.9
Maraganore, D.M.10
Adler, C.H.11
Larvor, L.12
Chartier-Harlin, M.-C.13
Nilsson, C.14
Langston, J.W.15
Gwinn, K.16
Hattori, N.17
Farrer, M.J.18
-
31
-
-
0033681149
-
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
-
Betarbet, R.; Sherer, T. B.; MacKenzie, G.; Garcia-Osuna, M.; Panov, A. V.; Greenamyre, J. T. Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nat. Neurosci. 3: 1301-1306; 2000.
-
(2000)
Nat. Neurosci
, vol.3
, pp. 1301-1306
-
-
Betarbet, R.1
Sherer, T.B.2
MacKenzie, G.3
Garcia-Osuna, M.4
Panov, A.V.5
Greenamyre, J.T.6
-
32
-
-
0037229425
-
Subcutaneous rotenone exposure causes highly selective dopaminergic degeneration and alpha-synuclein aggregation
-
DOI 10.1006/exnr.2002.8072
-
Sherer, T. B.; Kim, J. H.; Betarbet, R.; Greenamyre, J. T. Subcutaneous rotenone exposure causes highly selective dopaminergic degeneration and a-synu-clein aggregation. Exp. Neurol 179: 9-16; 20 03. (Pubitemid 36062614)
-
(2003)
Experimental Neurology
, vol.179
, Issue.1
, pp. 9-16
-
-
Sherer, T.B.1
Kim, J.-H.2
Betarbet, R.3
Greenamyre, J.T.4
-
33
-
-
0344198025
-
Mechanism of Toxicity in Rotenone Models of Parkinson's Disease
-
Sherer, T. B.; Betarbet, R.; Testa, C. M.; Seo, B. B.; Richardson, J. R.; Kim, J. H., et al. Mechanism of toxicity in rotenone models of Parkinson's disease. J. Neurosci. 23: 10756-10764; 2003. (Pubitemid 37499681)
-
(2003)
Journal of Neuroscience
, vol.23
, Issue.34
, pp. 10756-10764
-
-
Sherer, T.B.1
Betarbet, R.2
Testa, C.M.3
Seo, B.B.4
Richardson, J.R.5
Kim, J.H.6
Miller, G.W.7
Yagi, T.8
Matsuno-Yagi, A.9
Greenamyre, J.T.10
-
34
-
-
0042521076
-
The environment and Parkinson's disease: Is the nigrostriatal system preferentially targeted by neurotoxins?
-
DOI 10.1016/S1474-4422(03)00501-5
-
Di Monte, D. A. The environment and Parkinson's disease: is the nigrostriatal system preferentially targeted by neurotoxins? Lancet Neurol 2: 531-538; 2003. (Pubitemid 36994992)
-
(2003)
Lancet Neurology
, vol.2
, Issue.9
, pp. 531-538
-
-
Di Monte, D.A.1
-
35
-
-
52049111378
-
Update in the epidemiology of Parkinson's disease
-
Elbaz, A.; Moisan, F. Update in the epidemiology of Parkinson's disease. Curr. Opin. Neurol. 21: 454-460; 2008.
-
(2008)
Curr. Opin. Neurol
, vol.21
, pp. 454-460
-
-
Elbaz, A.1
Moisan, F.2
-
36
-
-
0034950069
-
Prospective study of caffeine consumption and risk of Parkinson's disease in men and women
-
Ascherio, A.; Zhang, S. M.; Hernan, M. A.; Kawachi, I.; Colditz, G. A.; Speizer, F. E., et al. Prospective study of caffeine consumption and risk of Parkinson's disease in men and women. Ann. Neurol 50: 56-63; 2001.
-
(2001)
Ann. Neurol
, vol.50
, pp. 56-63
-
-
Ascherio, A.1
Zhang, S.M.2
Hernan, M.A.3
Kawachi, I.4
Colditz, G.A.5
Speizer, F.E.6
-
37
-
-
0037379324
-
Genetic and environmental factors in the cause of Parkinson's disease
-
Warner, T. T.; Schapira, A. H. Genetic and environmental factors in the cause of Parkinson's disease. Ann. Neurol 53(Suppl. 3):S16-S23; 2003.
-
(2003)
Ann. Neurol
, vol.53
, Issue.SUPPL. 3
-
-
Warner, T.T.1
Schapira, A.H.2
-
38
-
-
10544234193
-
Mapping of a gene for Parkinson's disease to chromosome 4q21-q23
-
DOI 10.1126/science.274.5290.1197
-
Polymeropoulos, M. H.; Higgins, J. J.; Golbe, L. I.; Johnson, W. G.; Ide, S. E.; Di, I. G., et al. Mapping of a gene for Parkinson's disease to chromosome 4q21-q23. Science 274: 119 7 -1199; 1996. (Pubitemid 26389286)
-
(1996)
Science
, vol.274
, Issue.5290
, pp. 1197-1199
-
-
Polymeropoulos, M.H.1
Higgins, J.J.2
Golbe, L.I.3
Johnson, W.G.4
Ide, S.E.5
Di Iorio, G.6
Sanges, G.7
Stenroos, E.S.8
Pho, L.T.9
Schaffer, A.A.10
Lazzarini, A.M.11
Nussbaum, R.L.12
Duvoisin, R.C.13
-
39
-
-
0030744876
-
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease
-
DOI 10.1126/science.276.5321.2045
-
Polymeropoulos, M. H.; Lavedan, C.; Leroy, E.; Ide, S. E.; Dehejia, A.; Dutra, A., et al. Mutation in the a-synuclein gene identified in families with Parkinson's disease. Science 276: 2045-2047; 1997. (Pubitemid 27443610)
-
(1997)
Science
, vol.276
, Issue.5321
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
Pike, B.7
Root, H.8
Rubenstein, J.9
Boyer, R.10
Stenroos, E.S.11
Chandrasekharappa, S.12
Athanassiadou, A.13
Papapetropoulos, T.14
Johnson, W.G.15
Lazzarini, A.M.16
Duvoisin, R.C.17
Di Iorio, G.18
Golbe, L.I.19
Nussbaum, R.L.20
more..
-
40
-
-
0030882856
-
A-Synuclein in Lewy bodies
-
Spillantini, M. G.; Schmidt, M. L.; Lee, V. M.; Trojanowski, J. Q.; Jakes, R.; Goedert, M. a-Synuclein in Lewy bodies. Nature 388: 839-840; 1997.
-
(1997)
Nature
, vol.388
, pp. 839-840
-
-
Spillantini, M.G.1
Schmidt, M.L.2
Lee, V.M.3
Trojanowski, J.Q.4
Jakes, R.5
Goedert, M.6
-
41
-
-
40749152391
-
Parkinson's disease: A genetic perspective
-
DOI 10.1111/j.1742-4658.2008.06301.x
-
Belin, A. C.; Westerlund, M. Parkinson's disease: a genetic perspective. FEBS J 275: 1377-1383; 2008. (Pubitemid 351388789)
-
(2008)
FEBS Journal
, vol.275
, Issue.7
, pp. 1377-1383
-
-
Belin, A.C.1
Westerlund, M.2
-
42
-
-
70549084415
-
Genome-wide association study identifies common variants at four loci as genetic risk factors for parkinson's disease
-
Satake, W.; Nakabayashi, Y.; Mizuta, I.; Hirota, Y.; Ito, C.; Kubo, M., et al. Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease. Nat. Genet 41: 13 03 -13 07 ; 20 0 9 .
-
(2009)
Nat. Genet
, vol.41
, pp. 1303-1307
-
-
Satake, W.1
Nakabayashi, Y.2
Mizuta, I.3
Hirota, Y.4
Ito, C.5
Kubo, M.6
-
43
-
-
70549088602
-
Genome-wide association study reveals genetic risk underlying Parkinson's disease
-
Simon-Sanchez, J.; Schulte, C.; Bras, J. M.; Sharma, M.; Gibbs, J. R.; Berg, D., et al. Genome-wide association study reveals genetic risk underlying Parkinson's disease. Nat. Genet 41: 1308-1312; 2009.
-
(2009)
Nat. Genet
, vol.41
, pp. 1308-1312
-
-
Simon-Sanchez, J.1
Schulte, C.2
Bras, J.M.3
Sharma, M.4
Gibbs, J.R.5
Berg, D.6
-
44
-
-
58149100151
-
Genomewide association study for susceptibility genes contributing to familial Parkinson disease
-
Pankratz, N.; Wilk, J. B.; Latourelle, J. C.; DeStefano, A. L.; Halter, C.; Pugh, E. W., et al. Genomewide association study for susceptibility genes contributing to familial Parkinson disease. Hum. Genet. 124: 593-605; 2009.
-
(2009)
Hum. Genet
, vol.124
, pp. 593-605
-
-
Pankratz, N.1
Wilk, J.B.2
Latourelle, J.C.3
Destefano, A.L.4
Halter, C.5
Pugh, E.W.6
-
45
-
-
77956646167
-
Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease
-
Hamza, T. H.; Zabetian, C. P.; Tenesa, A.; Laederach, A.; Montimurro, J.; Yearout, D., et al. Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease. Nat. Genet 42: 781-785; 2010.
-
(2010)
Nat. Genet
, vol.42
, pp. 781-785
-
-
Hamza, T.H.1
Zabetian, C.P.2
Tenesa, A.3
Laederach, A.4
Montimurro, J.5
Yearout, D.6
-
46
-
-
60849121924
-
Characterization of PLA2G6 as a locus for dystonia-parkinsonism
-
Paisan-Ruiz, C.; Bhatia, K. P.; Li, A.; Hernandez, D.; Davis, M.; Wood, N. W., et al. Characterization of PLA2G6 as a locus for dystonia-parkinsonism. Ann. Neurol. 65: 19-23; 2009.
-
(2009)
Ann. Neurol
, vol.65
, pp. 19-23
-
-
Paisan-Ruiz, C.1
Bhatia, K.P.2
Li, A.3
Hernandez, D.4
Davis, M.5
Wood, N.W.6
-
47
-
-
59649088353
-
Fbxo7 mutations cause autosomal recessive early-onset parkinsonian- pyramidal syndrome
-
Di, F. A.; Dekker, M. C.; Montagna, P.; Baruzzi, A.; Yonova, E. H.; Correia, G. L., et al. FBXO7 mutations cause autosomal recessive, early-onset parkinsonian- pyramidal syndrome. Neurology 72: 240-245; 2009.
-
(2009)
Neurology
, vol.72
, pp. 240-245
-
-
Di, F.A.1
Dekker, M.C.2
Montagna, P.3
Baruzzi, A.4
Yonova, E.H.5
Correia, G.L.6
-
48
-
-
0036830525
-
A susceptibility gene for late-onset idiopathic Parkinson's disease
-
DOI 10.1002/ana.10324
-
Hicks, A. A.; Petursson, H.; Jonsson, T.; Stefansson, H.; Johannsdottir, H. S.; Sainz, J., et al. A susceptibility gene for late-onset idiopathic Parkinson's disease. Ann. Neurol. 52: 549-555; 2002. (Pubitemid 35246857)
-
(2002)
Annals of Neurology
, vol.52
, Issue.5
, pp. 549-555
-
-
Hicks, A.A.1
Petursson, H.2
Jonsson, T.3
Stefansson, H.4
Johannsdottir, H.S.5
Sainz, J.6
Frigge, M.L.7
Kong, A.8
Gulcher, J.R.9
Stefansson, K.10
Sveinbjornsdottir, S.11
-
49
-
-
41649096247
-
Mutations in the GIGYF2 (TNRC15) gene at the PARK11 locus in familial Parkinson disease
-
Lautier, C.; Goldwurm, S.; Durr, A.; Giovannone, B.; Tsiaras, W. G.; Pezzoli, G., et al. Mutations in the GIGYF2 (TNRC15) gene at the PARK11 locus in familial Parkinson disease. Am. J. Hum. Genet. 82: 822-833; 2008.
-
(2008)
Am. J. Hum. Genet
, vol.82
, pp. 822-833
-
-
Lautier, C.1
Goldwurm, S.2
Durr, A.3
Giovannone, B.4
Tsiaras, W.G.5
Pezzoli, G.6
-
50
-
-
0032190090
-
The ubiquitin pathway in parkinson's disease
-
Leroy, E.; Boyer, R.; Auburger, G.; Leube, B.; Ulm, G.; Mezey, E., et al. The ubiquitin pathway in Parkinson's disease. Nature 395: 451-452; 1998.
-
(1998)
Nature
, vol.395
, pp. 451-452
-
-
Leroy, E.1
Boyer, R.2
Auburger, G.3
Leube, B.4
Ulm, G.5
Mezey, E.6
-
51
-
-
0031951197
-
A susceptibility locus for Parkinson's disease maps to chromosome 2p13
-
DOI 10.1038/ng0398-262
-
Gasser, T.; Muller-Myhsok, B.; Wszolek, Z. K.; Oehlmann, R.; Calne, D. B.; Bonifati, V., et al. A susceptibility locus for Parkinson's disease maps to chromosome 2p13. Nat. Genet 18: 262-265; 1998. (Pubitemid 28117265)
-
(1998)
Nature Genetics
, vol.18
, Issue.3
, pp. 262-265
-
-
Gasser, T.1
Muller-Myhsok, B.2
Wszolek, Z.K.3
Oehlmann, R.4
Calne, D.B.5
Bonifati, V.6
Bereznai, B.7
Fabrizio, E.8
Vieregge, P.9
Horstmann, R.D.10
-
52
-
-
25444498785
-
Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease
-
DOI 10.1093/hmg/ddi215
-
Strauss, K. M.; Martins, L. M.; Plun-Favreau, H.; Marx, F. P.; Kautzmann, S.; Berg, D., et al. Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease. Hum. Mol. Genet 14: 2099-2111; 2005. (Pubitemid 41418010)
-
(2005)
Human Molecular Genetics
, vol.14
, Issue.15
, pp. 2099-2111
-
-
Strauss, K.M.1
Martins, L.M.2
Plun-Favreau, H.3
Marx, F.P.4
Kautzmann, S.5
Berg, D.6
Gasser, T.7
Wszolek, Z.8
Muller, T.9
Bornemann, A.10
Wolburg, H.11
Downward, J.12
Riess, O.13
Schulz, J.B.14
Kruger, R.15
-
53
-
-
10744223494
-
Genome-wide linkage analysis and evidence of gene-by-gene interactions in a sample of 362 multiplex Parkinson disease families
-
DOI 10.1093/hmg/ddg270
-
Pankratz, N.; Nichols, W. C.; Uniacke, S. K.; Halter, C.; Murrell, J.; Rudolph, A., et al. Genome-wide linkage analysis and evidence of gene-by-gene interactions in a sample of 362 multiplex Parkinson disease families. Hum. Mol. Genet 12: 2599-2608; 2003. (Pubitemid 37304683)
-
(2003)
Human Molecular Genetics
, vol.12
, Issue.20
, pp. 2599-2608
-
-
Pankratz, N.1
Nichols, W.C.2
Uniacke, S.K.3
Halter, C.4
Murrell, J.5
Rudolph, A.6
Shults, C.W.7
Conneally, P.M.8
Foroud, T.9
Truong, D.10
Pathak, M.11
Tran, A.12
Rodnitzky, R.13
Dobson, J.14
Koller, W.15
Weiner, W.16
Lyons, K.17
Kurlan, R.18
Berry, D.19
Bertoni, J.20
Peterson, C.21
Martin, W.22
Wieler, M.23
Tuite, P.24
Schacherer, R.25
Marder, K.26
Harris, J.27
Jankovic, J.28
Hunter, C.29
Lang, A.30
Kleimer-Fisman, G.31
Nieves, A.32
So, J.33
Factor, S.34
Evans, S.35
Manyam, B.36
Wulbrecht, B.37
Walker, F.38
Hunt, V.39
Gordon, M.F.40
Hamman, J.41
Kang, U.J.42
Young, J.43
Blindauer, K.44
Petit, J.45
Rao, J.46
Cook, M.47
Stacy, M.48
Williamson, K.49
Pullman, R.S.50
Boyar, K.51
Leehey, M.52
Derian, T.53
Gordon, P.54
Werner, J.55
Racette, B.56
Good, L.57
Simon, D.58
Scollins, L.59
Schwieterman, D.60
Dewey, R.61
Meacham, M.62
Sutton, J.63
Hutchinson, B.64
Jog, M.65
Horn, C.66
Sethi, K.67
Carpenter, J.68
Atchison, P.69
Rolli, S.70
Sudarsky, L.71
Corwin, C.72
Velickovic, M.73
Phipps, S.74
Simuni, T.75
Kaczmarek, A.76
Hermanowicz, N.77
Niswonger, S.78
Feigin, A.79
Shannon, B.80
Calabrese, V.81
Roberge, P.82
Homes, H.83
Shulman, L.84
Dustin, K.85
Ajax, T.86
Mannetter, J.87
Podskalny, G.D.88
Giffin, L.89
Uitti, R.90
Turk, M.F.91
more..
-
54
-
-
63149090431
-
Parkinson's disease: From monogenic forms to genetic susceptibility factors
-
Lesage, S.; Brice, A. Parkinson's disease: from monogenic forms to genetic susceptibility factors. Hum. Mol. Genet 18:R48-R59; 2009.
-
(2009)
Hum. Mol. Genet
, vol.18
-
-
Lesage, S.1
Brice, A.2
-
55
-
-
67749118059
-
LRRK2 gene variation and its contribution to Parkinson disease
-
Paisan-Ruiz, C. LRRK2 gene variation and its contribution to Parkinson disease. Hum. Mutat 30: 115 3 -1160; 2009.
-
(2009)
Hum. Mutat
, vol.30
, pp. 1153-1160
-
-
Paisan-Ruiz, C.1
-
56
-
-
0024210648
-
Lewy body disease with and without dementia: A clinicopathological study of 35 cases
-
Kosaka, K.; Tsuchiya, K.; Yoshimura, M. Lewy body disease with and without dementia: a clinicopathological study of 35 cases. Clin. Neuropathol 7: 299-305; 1988. (Pubitemid 19019180)
-
(1988)
Clinical Neuropathology
, vol.7
, Issue.6
, pp. 299-305
-
-
Kosaka, K.1
Tsuchiya, K.2
Yoshimura, M.3
-
57
-
-
0029414766
-
Nigral and extranigral pathology in Parkinson's disease
-
Braak, H.; Braak, E.; Yilmazer, D.; Schultz, C.; de Vos, R. A.; Jansen, E. N. Nigral and extranigral pathology in Parkinson's disease. J. Neural Transm. Suppl. 46: 15-31; 1995. (Pubitemid 26043220)
-
(1995)
Journal of Neural Transmission, Supplement
, Issue.46
, pp. 15-31
-
-
Braak, H.1
Braak, E.2
Yilmazer, D.3
Schultz, C.4
De Vos, R.A.I.5
Jansen, E.N.H.6
-
58
-
-
0036869851
-
Selective loss of pyramidal neurons in the pre-supplementary motor cortex in Parkinson's disease
-
DOI 10.1002/mds.10258
-
Macdonald, V.; Halliday, G. M. Selective loss of pyramidal neurons in the pre-supplementary motor cortex in Parkinson's disease. Mov. Disord 17: 1166-117 3 ; 2 0 0 2 . (Pubitemid 36041329)
-
(2002)
Movement Disorders
, vol.17
, Issue.6
, pp. 1166-1173
-
-
MacDonald, V.1
Halliday, G.M.2
-
59
-
-
0033621975
-
Degeneration of the centre median-parafascicular complex in Parkinson's disease
-
DOI 10.1002/1531-8249(200003)47:3<345::AID-ANA10>3.0.CO;2-V
-
Henderson, J. M.; Carpenter, K.; Cartwright, H.; Halliday, G. M. Degeneration of the centre median-parafascicular complex in Parkinson's disease. Ann. Neurol 47: 345-352; 2000. (Pubitemid 30141844)
-
(2000)
Annals of Neurology
, vol.47
, Issue.3
, pp. 345-352
-
-
Henderson, J.M.1
Carpenter, K.2
Cartwright, H.3
Halliday, G.M.4
-
60
-
-
0031105375
-
Specific A10 dopaminergic nuclei in the midbrain degenerate in Parkinson's disease
-
DOI 10.1006/exnr.1997.6418
-
McRitchie, D. A.; Cartwright, H. R.; Halliday, G. M. Specific A10 dopaminergic nuclei in the midbrain degenerate in Parkinson's disease. Exp. Neurol 144: 202-213; 1997. (Pubitemid 27149624)
-
(1997)
Experimental Neurology
, vol.144
, Issue.1
, pp. 202-213
-
-
McRitchie, D.A.1
Cartwright, H.R.2
Halliday, G.M.3
-
61
-
-
79955746757
-
The cholinergic system and Parkinson disease
-
Bohnen, N. I.; Albin, R. L. The cholinergic system and Parkinson disease. Behav. Brain Res. 221: 564-573; 2011.
-
(2011)
Behav. Brain Res
, vol.221
, pp. 564-573
-
-
Bohnen, N.I.1
Albin, R.L.2
-
62
-
-
34250841699
-
Hypocretin (orexin) loss in Parkinson's disease
-
DOI 10.1093/brain/awm090
-
Fronczek, R.; Overeem, S.; Lee, S. Y.; Hegeman, I. M.; van, P. J.; van Duinen, S. G., et al. Hypocretin (orexin) loss in Parkinson's disease. Brain 130: 157 7 -15 85 ; 2007. (Pubitemid 47355929)
-
(2007)
Brain
, vol.130
, Issue.6
, pp. 1577-1585
-
-
Fronczek, R.1
Overeem, S.2
Lee, S.Y.Y.3
Hegeman, I.M.4
Van Pelt, J.5
Van Duinen, S.G.6
Lammers, G.J.7
Swaab, D.F.8
-
63
-
-
34250897889
-
Hypocretin (orexin) cell loss in Parkinson's disease
-
DOI 10.1093/brain/awm097
-
Thannickal, T. C.; Lai, Y. Y.; Siegel, J. M. Hypocretin (orexin) cell loss in Parkinson's disease. Brain 130: 1586-1595; 2007. (Pubitemid 47355933)
-
(2007)
Brain
, vol.130
, Issue.6
, pp. 1586-1595
-
-
Thannickal, T.C.1
Lai, Y.-Y.2
Siegel, J.M.3
-
64
-
-
84950170900
-
Neuropathology of immunohistochemically identified brainstem neurons in Parkinson's disease
-
Halliday, G. M.; Li, Y. W.; Blumbergs, P. C.; Joh, T. H.; Cotton, R. G.; Howe, P. R., et al. Neuropathology of immunohistochemically identified brainstem neurons in Parkinson's disease. Ann. Neurol. 27: 373-385; 1990. (Pubitemid 20132052)
-
(1990)
Annals of Neurology
, vol.27
, Issue.4
, pp. 373-385
-
-
Halliday, G.M.1
Li, Y.W.2
Blumbergs, P.C.3
Joh, T.H.4
Cotton, R.G.H.5
Howe, P.R.C.6
Blessing, W.W.7
Geffen, L.B.8
-
65
-
-
0036844873
-
Clinical correlates of selective pathology in the amygdala of patients with Parkinson's disease
-
Harding, A. J.; Stimson, E.; Henderson, J. M.; Halliday, G. M. Clinical correlates of selective pathology in the amygdala of patients with Parkinson's disease. Brain 125: 2431-2445; 2002. (Pubitemid 35303503)
-
(2002)
Brain
, vol.125
, Issue.11
, pp. 2431-2445
-
-
Harding, A.J.1
Stimson, E.2
Henderson, J.M.3
Halliday, G.M.4
-
66
-
-
78349273066
-
Brain stem pathology in Parkinson's disease: An evaluation of the Braak staging model
-
Kingsbury, A. E.; Bandopadhyay, R.; Silveira-Moriyama, L.; Ayling, H.; Kallis, C.; Sterlacci, W., et al. Brain stem pathology in Parkinson's disease: an evaluation of the Braak staging model. Mov. Disord 25: 2508-2515; 2010.
-
(2010)
Mov. Disord
, vol.25
, pp. 2508-2515
-
-
Kingsbury, A.E.1
Bandopadhyay, R.2
Silveira-Moriyama, L.3
Ayling, H.4
Kallis, C.5
Sterlacci, W.6
-
67
-
-
0028907136
-
Image analyser-assisted morphometry of the locus coeruleus in alzheimer's disease parkinson's disease and amyotrophic lateral sclerosis
-
Hoogendijk, W. J.; Pool, C. W.; Troost, D.; van, Z. E.; Swaab, D. F. Image analyser-assisted morphometry of the locus coeruleus in Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis. Brain 118(Pt 1): 131-143; 1995.
-
(1995)
Brain
, vol.118
, Issue.PART 1
, pp. 131-143
-
-
Hoogendijk, W.J.1
Pool, C.W.2
Troost, D.3
Van, Z.E.4
Swaab, D.F.5
-
68
-
-
14944344707
-
No global loss of neocortical neurons in Parkinson's disease: A quantitative stereological study
-
DOI 10.1002/mds.20289
-
Pedersen, K. M.; Marner, L.; Pakkenberg, H.; Pakkenberg, B. No global loss of neocortical neurons in Parkinson's disease: a quantitative stereological study. Mov. Disord 20: 164-171; 2005. (Pubitemid 40361119)
-
(2005)
Movement Disorders
, vol.20
, Issue.2
, pp. 164-171
-
-
Pedersen, K.M.1
Marner, L.2
Pakkenberg, H.3
Pakkenberg, B.4
-
69
-
-
0029839838
-
Regional brain atrophy in idiopathic Parkinson's disease and diffuse Lewy body disease
-
Double, K. L.; Halliday, G. M.; McRitchie, D. A.; Reid, W. G.; Hely, M. A.; Morris, J. G. Regional brain atrophy in idiopathic Parkinson's disease and diffuse Lewy body disease. Dementia 7: 304-313; 1996. (Pubitemid 26341259)
-
(1996)
Dementia
, vol.7
, Issue.6
, pp. 304-313
-
-
Double, K.L.1
Halliday, G.M.2
McRitchie, D.A.3
Reid, W.G.J.4
Hely, M.A.5
Morris, J.G.L.I.6
Glenda, H.7
-
70
-
-
77951247114
-
Gray matter correlations of cognition in incident Parkinson's disease
-
Dalaker, T. O.; Zivadinov, R.; Larsen, J. P.; Beyer, M. K.; Cox, J. L.; Alves, G., et al. Gray matter correlations of cognition in incident Parkinson's disease. Mov. Disord 25: 629-633; 2010.
-
(2010)
Mov. Disord
, vol.25
, pp. 629-633
-
-
Dalaker, T.O.1
Zivadinov, R.2
Larsen, J.P.3
Beyer, M.K.4
Cox, J.L.5
Alves, G.6
-
71
-
-
0036392590
-
Staging of the intracerebral inclusion body pathology associated with idiopathic Parkinson's disease (preclinical and clinical stages)
-
Braak, H.; Del, T. K.; Bratzke, H.; Hamm-Clement, J.; Sandmann-Keil, D.; Rub, U. Staging of the intracerebral inclusion body pathology associated with idiopathic Parkinson's disease (preclinical and clinical stages). J. Neurol. 249(Suppl. 3); 2002. III/1-III/5.
-
(2002)
J. Neurol
, vol.249
, Issue.SUPPL. 3
-
-
Braak, H.1
Del, T.K.2
Bratzke, H.3
Hamm-Clement, J.4
Sandmann-Keil, D.5
Rub, U.6
-
72
-
-
0037333666
-
Staging of brain pathology related to sporadic Parkinson's disease
-
DOI 10.1016/S0197-4580(02)00065-9, PII S0197458002000659
-
Braak, H.; Del, T. K.; Rub, U.; de Vos, R. A.; Jansen Steur, E. N.; Braak, E. Staging of brain pathology related to sporadic Parkinson's disease. Neurobiol. Aging 24: 197-211; 2003. (Pubitemid 36007810)
-
(2003)
Neurobiology of Aging
, vol.24
, Issue.2
, pp. 197-211
-
-
Braak, H.1
Del Tredici, K.2
Rub, U.3
De Vos, R.A.I.4
Jansen Steur, E.N.H.5
Braak, E.6
-
73
-
-
5444255434
-
Stages in the development of Parkinson's disease-related pathology
-
DOI 10.1007/s00441-004-0956-9
-
Braak, H.; Ghebremedhin, E.; Rub, U.; Bratzke, H.; Del, T. K. Stages in the development of Parkinson's disease-related pathology. Cell Tissue Res 318: 121-134; 2004. (Pubitemid 39362633)
-
(2004)
Cell and Tissue Research
, vol.318
, Issue.1
, pp. 121-134
-
-
Braak, H.1
Ghebremedhin, E.2
Rub, U.3
Bratzke, H.4
Del Tredici, K.5
-
75
-
-
77949897463
-
The progression of pathology in Parkinson's disease
-
Halliday, G. M.; McCann, H. The progression of pathology in Parkinson's disease. Ann. N. Y. Acad. Sci. 1184: 188-195; 2010.
-
(2010)
Ann. N. Y. Acad. Sci
, vol.1184
, pp. 188-195
-
-
Halliday, G.M.1
McCann, H.2
-
77
-
-
52449117926
-
Research in motion: The enigma of Parkinson's disease pathology spread
-
Brundin, P.; Li, J. Y.; Holton, J. L.; Lindvall, O.; Revesz, T. Research in motion: the enigma of Parkinson's disease pathology spread. Nat. Rev. Neurosci. 9: 741-745; 2008.
-
(2008)
Nat. Rev. Neurosci
, vol.9
, pp. 741-745
-
-
Brundin, P.1
Li, J.Y.2
Holton, J.L.3
Lindvall, O.4
Revesz, T.5
-
78
-
-
42549125030
-
The dorsal motor nucleus of the vagus is not an obligatory trigger site of Parkinson's disease: A critical analysis of alpha-synuclein staging
-
DOI 10.1111/j.1365-2990.2007.00923.x
-
Kalaitzakis, M. E.; Graeber, M. B.; Gentleman, S. M.; Pearce, R. K. The dorsal motor nucleus of the vagus is not an obligatory trigger site of Parkinson's disease: a critical analysis of a-synuclein staging. Neuropathol. Appl. Neuro-biol 34: 284-295; 2008. (Pubitemid 351590870)
-
(2008)
Neuropathology and Applied Neurobiology
, vol.34
, Issue.3
, pp. 284-295
-
-
Kalaitzakis, M.E.1
Graeber, M.B.2
Gentleman, S.M.3
Pearce, R.K.B.4
-
79
-
-
47749147444
-
The dorsal motor nucleus of the vagus is not an obligatory trigger site of Parkinson's disease
-
Attems, J.; Jellinger, K. A. The dorsal motor nucleus of the vagus is not an obligatory trigger site of Parkinson's disease. Neuropathol. Appl. Neurobiol 34: 466-467; 2008.
-
(2008)
Neuropathol. Appl. Neurobiol
, vol.34
, pp. 466-467
-
-
Attems, J.1
Jellinger, K.A.2
-
80
-
-
68649112842
-
Oxidative and nitrosative stress in Parkinson's disease
-
Tsang, A. H.; Chung, K. K. Oxidative and nitrosative stress in Parkinson's disease. Biochim. Biophys. Acta 1792: 643-650; 2009.
-
(2009)
Biochim. Biophys. Acta
, vol.1792
, pp. 643-650
-
-
Tsang, A.H.1
Chung, K.K.2
-
81
-
-
42649144101
-
Oxidative and nitrative protein modifications in Parkinson's disease
-
Danielson, S. R.; Andersen, J. K. Oxidative and nitrative protein modifications in Parkinson's disease. Free Radic. Biol. Med. 44: 1787-1794; 2008.
-
(2008)
Free Radic. Biol. Med
, vol.44
, pp. 1787-1794
-
-
Danielson, S.R.1
Andersen, J.K.2
-
82
-
-
74149087316
-
Oxidative damage in Parkinson disease: Measurement using accurate bio-markers
-
Seet, R. C.; Lee, C. Y.; Lim, E. C.; Tan, J. J.; Quek, A. M.; Chong, W. L., et al. Oxidative damage in Parkinson disease: measurement using accurate bio-markers. Free Radic. Biol. Med. 48: 560-566; 2010.
-
(2010)
Free Radic. Biol. Med
, vol.48
, pp. 560-566
-
-
Seet, R.C.1
Lee, C.Y.2
Lim, E.C.3
Tan, J.J.4
Quek, A.M.5
Chong, W.L.6
-
83
-
-
76949089544
-
Brain mitochondrial dysfunction and oxidative damage in Parkinson's disease
-
Navarro, A.; Boveris, A. Brain mitochondrial dysfunction and oxidative damage in Parkinson's disease. J. Bioenerg. Biomembr 41: 517-521; 2009.
-
(2009)
J. Bioenerg. Biomembr
, vol.41
, pp. 517-521
-
-
Navarro, A.1
Boveris, A.2
-
84
-
-
0033681149
-
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
-
Betarbet, R.; Sherer, T. B.; MacKenzie, G.; Garcia-Osuna, M.; Panov, A. V.; Greenamyre, J. T. Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nat. Neurosci. 3: 1301-1306; 2000.
-
(2000)
Nat. Neurosci
, vol.3
, pp. 1301-1306
-
-
Betarbet, R.1
Sherer, T.B.2
MacKenzie, G.3
Garcia-Osuna, M.4
Panov, A.V.5
Greenamyre, J.T.6
-
85
-
-
0024585155
-
Basal lipid peroxidation in substantia nigra is increased in Parkinson's disease
-
DOI 10.1111/j.1471-4159.1989.tb09133.x
-
Dexter, D. T.; Carter, C. J.; Wells, F. R.; Javoy-Agid, F.; Agid, Y.; Lees, A., et al. Basal lipid peroxidation in substantia nigra is increased in Parkinson's disease. J. Neurochem 52: 381-389; 1989. (Pubitemid 19037600)
-
(1989)
Journal of Neurochemistry
, vol.52
, Issue.2
, pp. 381-389
-
-
Dexter, D.T.1
Carter, C.J.2
Wells, F.R.3
Javoy-Agid, F.4
Agid, Y.5
Lees, A.6
Jenner, P.7
Marsden, C.D.8
-
86
-
-
0029917194
-
Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease
-
DOI 10.1073/pnas.93.7.2696
-
Yoritaka, A.; Hattori, N.; Uchida, K.; Tanaka, M.; Stadtman, E. R.; Mizuno, Y. Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease. Proc. Natl. Acad. Sci. USA 93: 2696-2701; 1996. (Pubitemid 26114311)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.7
, pp. 2696-2701
-
-
Yoritaka, A.1
Hattori, N.2
Uchida, K.3
Tanaka, M.4
Stadtman, E.R.5
Mizuno, Y.6
-
87
-
-
0030878073
-
Oxidative DNA damage in the Parkinsonian brain: An apparent selective increase in 8-hydroxyguanine levels in substantia nigra
-
Alam, Z. I.; Jenner, A.; Daniel, S. E.; Lees, A. J.; Cairns, N.; Marsden, C. D., et al. Oxidative DNA damage in the parkinsonian brain: an apparent selective increase in 8-hydroxyguanine levels in substantia nigra. J. Neurochem 69: 11 9 6 -1203; 1997. (Pubitemid 27364841)
-
(1997)
Journal of Neurochemistry
, vol.69
, Issue.3
, pp. 1196-1203
-
-
Alam, Z.I.1
Jenner, A.2
Daniel, S.E.3
Lees, A.J.4
Cairns, N.5
Marsden, C.D.6
Jenner, P.7
Halliwell, B.8
-
88
-
-
0032911488
-
Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons
-
Zhang, J.; Perry, G.; Smith, M. A.; Robertson, D.; Olson, S. J.; Graham, D. G., et al. Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons. Am. J. Pathol 154: 1423-1429; 1999. (Pubitemid 29226437)
-
(1999)
American Journal of Pathology
, vol.154
, Issue.5
, pp. 1423-1429
-
-
Zhang, J.1
Perry, G.2
Smith, M.A.3
Robertson, D.4
Olson, S.J.5
Graham, D.G.6
Montine, T.J.7
-
89
-
-
0030805622
-
A generalised increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease
-
Alam, Z. I.; Daniel, S. E.; Lees, A. J.; Marsden, D. C.; Jenner, P.; Halliwell, B. A generalised increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease. J. Neurochem 69: 1326-1329; 1997. (Pubitemid 27364859)
-
(1997)
Journal of Neurochemistry
, vol.69
, Issue.3
, pp. 1326-1329
-
-
Alam, Z.I.1
Daniel, S.E.2
Lees, A.J.3
Marsden, D.C.4
Jenner, P.5
Halliwell, B.6
-
90
-
-
0031962268
-
Increased protein oxidation in human substantia nigra pars compacta in comparison with basal ganglia and prefrontal cortex measured with an improved dinitrophenylhydrazine assay
-
Floor, E.; Wetzel, M. G. Increased protein oxidation in human substantia nigra pars compacta in comparison with basal ganglia and prefrontal cortex measured with an improved dinitrophenylhydrazine assay. J. Neurochem 70: 268-275; 1998. (Pubitemid 28020852)
-
(1998)
Journal of Neurochemistry
, vol.70
, Issue.1
, pp. 268-275
-
-
Floor, E.1
Wetzel, M.G.2
-
91
-
-
0031939204
-
Protein nitration in Parkinson's disease
-
Good, P. F.; Hsu, A.; Werner, P.; Perl, D. P.; Olanow, C. W. Protein nitration in Parkinson's disease. J. Neuropathol. Exp. Neurol. 57: 338-342; 1998. (Pubitemid 28182632)
-
(1998)
Journal of Neuropathology and Experimental Neurology
, vol.57
, Issue.4
, pp. 338-342
-
-
Good, P.F.1
Hsu, A.2
Werner, P.3
Perl, D.P.4
Warren Olanow, C.5
-
92
-
-
0033678217
-
Widespread nitration of pathological inclusions in neurodegenerative synu-cleinopathies
-
Duda, J. E.; Giasson, B. I.; Chen, Q.; Gur, T. L.; Hurtig, H. I.; Stern, M. B., et al. Widespread nitration of pathological inclusions in neurodegenerative synu-cleinopathies. Am. J. Pathol. 157: 1439-1445; 2000.
-
(2000)
Am. J. Pathol
, vol.157
, pp. 1439-1445
-
-
Duda, J.E.1
Giasson, B.I.2
Chen, Q.3
Gur, T.L.4
Hurtig, H.I.5
Stern, M.B.6
-
93
-
-
0033608739
-
Increased nitrotyrosine immunoreactivity in substantia nigra neurons in MPTP treated baboons is blocked by inhibition of neuronal nitric oxide synthase
-
DOI 10.1016/S0006-8993(99)01166-X, PII S000689939901166X
-
Ferrante, R. J.; Hantraye, P.; Brouillet, E.; Beal, M. F. Increased nitrotyrosine immunoreactivity in substantia nigra neurons in MPTP treated baboons is blocked by inhibition of neuronal nitric oxide synthase. Brain Res 823: 17 7 -182; 1999. (Pubitemid 29225506)
-
(1999)
Brain Research
, vol.823
, Issue.1-2
, pp. 177-182
-
-
Ferrante, R.J.1
Hantraye, P.2
Brouillet, E.3
Beal, M.F.4
-
94
-
-
0033521095
-
Mass spectrometric quantification of 3-nitrotyrosine, ortho-tyrosine, and o,o0-dityrosine in brain tissue of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine-treated mice, a model of oxidative stress in Parkinson's disease
-
Pennathur, S.; Jackson-Lewis, V.; Przedborski, S.; Heinecke, J. W. Mass spectrometric quantification of 3-"nitrotyrosine, ortho-tyrosine, and o,o0 -dityrosine in brain tissue of 1-"methyl-4-phenyl-1,2,3,6-tetrahydropyr- idine-treated mice, a model of oxidative stress in Parkinson's disease. J. Biol. Chem 274: 34621-34628; 1999. (Pubitemid 129509499)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.49
, pp. 34621-34628
-
-
Pennathur, S.1
Jackson-Lewis, V.2
Przedborski, S.3
Heinecke, J.W.4
-
95
-
-
0020308323
-
Parkinson's disease: A disorder due to nigral glutathione deficiency?
-
DOI 10.1016/0304-3940(82)90390-1
-
Perry, T. L.; Godin, D. V.; Hansen, S. Parkinson's disease: a disorder due to nigral glutathione deficiency? Neurosci. Lett. 33: 305-310; 1982. (Pubitemid 13119539)
-
(1982)
Neuroscience Letters
, vol.33
, Issue.3
, pp. 305-310
-
-
Perry, T.L.1
Godin, D.V.2
Hansen, S.3
-
96
-
-
0022553605
-
Idiopathic Parkinson's disease, progressive supranuclear palsy and glutathione metabolism in the substantia nigra of patients
-
DOI 10.1016/0304-3940(86)90320-4
-
Perry, T. L.; Yong, V. W. Idiopathic Parkinson's disease, progressive supra-nuclear palsy and glutathione metabolism in the substantia nigra of patients. Neurosci. Lett 67: 269-274; 1986. (Pubitemid 16038336)
-
(1986)
Neuroscience Letters
, vol.67
, Issue.3
, pp. 269-274
-
-
Perry, T.L.1
Yong, V.W.2
-
97
-
-
0030724621
-
Alterations in the distribution of glutathione in the substantia nigra in Parkinson's disease
-
DOI 10.1007/BF01291884
-
Pearce, R. K.; Owen, A.; Daniel, S.; Jenner, P.; Marsden, C. D. Alterations in the distribution of glutathione in the substantia nigra in Parkinson's disease. J. Neural Transm 104: 661-677; 1997. (Pubitemid 27474680)
-
(1997)
Journal of Neural Transmission
, vol.104
, Issue.6-7
, pp. 661-677
-
-
Pearce, R.K.B.1
Owen, A.2
Daniel, S.3
Jenner, P.4
Marsden, C.D.5
-
98
-
-
0026637866
-
Why are nigral catecholaminergic neurons more vulnerable than other cells in Parkinson's disease?
-
Hirsch, E. C. Why are nigral catecholaminergic neurons more vulnerable than other cells in Parkinson's disease? Ann. Neurol 32(Suppl):S88-S93; 1992.
-
(1992)
Ann. Neurol
, vol.32
, Issue.SUPPL.
-
-
Hirsch, E.C.1
-
99
-
-
34247631275
-
Multiple hit hypotheses for dopamine neuron loss in Parkinson's disease
-
DOI 10.1016/j.tins.2007.03.009, PII S0166223607000707, Fifty years of dopamine research
-
Sulzer, D. Multiple hit hypotheses for dopamine neuron loss in Parkinson's disease. Trends Neurosci 30: 244-250; 2007. (Pubitemid 46667168)
-
(2007)
Trends in Neurosciences
, vol.30
, Issue.5
, pp. 244-250
-
-
Sulzer, D.1
-
100
-
-
0035662768
-
Substantia nigra neuromelanin: Structure, synthesis, and molecular behaviour
-
Zecca, L.; Tampellini, D.; Gerlach, M.; Riederer, P.; Fariello, R. G.; Sulzer, D. Substantia nigra neuromelanin: structure, synthesis, and molecular behaviour. Mol. Pathol 54: 414-418; 2001. (Pubitemid 34025257)
-
(2001)
Journal of Clinical Pathology - Molecular Pathology
, vol.54
, Issue.6
, pp. 414-418
-
-
Zecca, L.1
Tampellini, D.2
Gerlach, M.3
Riederer, P.4
Fariello, R.G.5
Sulzer, D.6
-
101
-
-
0024356620
-
Increased nigral iron content and alterations in other metal ions occurring in brain in Parkinson's disease
-
DOI 10.1111/j.1471-4159.1989.tb07264.x
-
Dexter, D. T.; Wells, F. R.; Lees, A. J.; Agid, F.; Agid, Y.; Jenner, P., et al. Increased nigral iron content and alterations in other metal ions occurring in brain in Parkinson's disease. J. Neurochem 52: 1830-1836; 1989. (Pubitemid 19140770)
-
(1989)
Journal of Neurochemistry
, vol.52
, Issue.6
, pp. 1830-1836
-
-
Dexter, D.T.1
Wells, F.R.2
Lees, A.J.3
Agid, F.4
Agid, Y.5
Jenner, P.6
Marsden, C.D.7
-
102
-
-
0028643643
-
Hydroxyl radicals, iron, oxidative stress, and neurodegen-eration
-
Gutteridge, J. M. Hydroxyl radicals, iron, oxidative stress, and neurodegen-eration. Ann. N. Y. Acad. Sci. 738: 201-213; 1994.
-
(1994)
Ann. N. Y. Acad. Sci
, vol.738
, pp. 201-213
-
-
Gutteridge, J.M.1
-
103
-
-
48749123360
-
Neuromelanin can protect against iron-mediated oxidative damage in system modeling iron overload of brain aging and parkinson's disease
-
Zecca, L.; Casella, L.; Albertini, A.; Bellei, C.; Zucca, F. A.; Engelen, M., et al. Neuromelanin can protect against iron-mediated oxidative damage in system modeling iron overload of brain aging and Parkinson's disease. J. Neurochem 106: 1866-1875; 2008.
-
(2008)
J. Neurochem
, vol.106
, pp. 1866-1875
-
-
Zecca, L.1
Casella, L.2
Albertini, A.3
Bellei, C.4
Zucca, F.A.5
Engelen, M.6
-
104
-
-
80051801621
-
The relevance of iron in the pathogenesis of Parkinson's disease
-
Sian-Hulsmann, J.; Mandel, S.; Youdim, M. B.; Riederer, P. The relevance of iron in the pathogenesis of Parkinson's disease. J. Neurochem 11 8 : 939-957; 2011.
-
(2011)
J. Neurochem
, vol.118
, pp. 939-957
-
-
Sian-Hulsmann, J.1
Mandel, S.2
Youdim, M.B.3
Riederer, P.4
-
105
-
-
0028972818
-
Implication of dopamine transporter system on 1-methyl-4-phenylpyridinium and rotenone effect in striatal synaptosomes
-
DOI 10.1016/0922-4106(95)90083-7
-
Bougria, M.; Vitorica, J.; Cano, J.; Machado, A. Implication of dopamine transporter system on 1-methyl-4-phenylpyridinium and rotenone effect in striatal synaptosomes. Eur. J. Pharmacol 291: 407-415; 1995. (Pubitemid 3014609)
-
(1995)
European Journal of Pharmacology - Molecular Pharmacology Section
, vol.291
, Issue.3
, pp. 407-415
-
-
Bougria, M.1
Vitorica, J.2
Cano, J.3
Machado, A.4
-
106
-
-
34249788747
-
Pesticides and impairment of mitochondrial function in relation with the parkinsonian syndrome
-
DOI 10.2741/2128
-
Gomez, C.; Bandez, M. J.; Navarro, A. Pesticides and impairment of mito-chondrial function in relation with the parkinsonian syndrome. Front. Biosci 12: 1079-1093; 2007. (Pubitemid 46846880)
-
(2007)
Frontiers in Bioscience
, vol.12
, Issue.3
, pp. 1079-1093
-
-
Gomez, C.1
Bandez, M.J.2
Navarro, A.3
-
107
-
-
55849122639
-
Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis
-
Henchcliffe, C.; Beal, M. F. Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis. Nat. Clin. Pract. Neurol. 4: 600-609; 2008.
-
(2008)
Nat. Clin. Pract. Neurol
, vol.4
, pp. 600-609
-
-
Henchcliffe, C.1
Beal, M.F.2
-
108
-
-
1042301416
-
Characterization of Superoxide-producing Sites in Isolated Brain Mitochondria
-
DOI 10.1074/jbc.M310341200
-
Kudin, A. P.; Bimpong-Buta, N. Y.; Vielhaber, S.; Elger, C. E.; Kunz, W. S. Characterization of superoxide-producing sites in isolated brain mitochondria. J. Biol. Chem. 279: 4127-4135; 2004. (Pubitemid 38198997)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.6
, pp. 4127-4135
-
-
Kudin, A.P.1
Bimpong-Buta, N.Y.-B.2
Vielhaber, S.3
Elger, C.E.4
Kunz, W.S.5
-
109
-
-
0028316759
-
Unaltered aconitase activity, but decreased complex I activity in substantia nigra pars compacta of patients with Parkinson's disease
-
DOI 10.1016/0304-3940(94)90372-7
-
Janetzky, B.; Hauck, S.; Youdim, M. B.; Riederer, P.; Jellinger, K.; Pantucek, F., et al. Unaltered aconitase activity, but decreased complex I activity in substantia nigra pars compacta of patients with Parkinson's disease. Neurosci. Lett 169: 126-128; 1994. (Pubitemid 24108879)
-
(1994)
Neuroscience Letters
, vol.169
, Issue.1-2
, pp. 126-128
-
-
Janetzky, B.1
Hauck, S.2
Youdim, M.B.H.3
Riederer, P.4
Jellinger, K.5
Pantucek, F.6
Zochling, R.7
Boissl, K.W.8
Reichmann, H.9
-
110
-
-
0025254401
-
Mitochondrial complex i deficiency in Parkinson's disease
-
Schapira, A. H.; Cooper, J. M.; Dexter, D.; Clark, J. B.; Jenner, P.; Marsden, C. D. Mitochondrial complex I deficiency in Parkinson's disease. J. Neurochem. 54: 823-827; 1990.
-
(1990)
J. Neurochem
, vol.54
, pp. 823-827
-
-
Schapira, A.H.1
Cooper, J.M.2
Dexter, D.3
Clark, J.B.4
Jenner, P.5
Marsden, C.D.6
-
111
-
-
0024390719
-
Mitochondrial complex I deficiency in Parkinson's disease
-
Schapira, A. H.; Cooper, J. M.; Dexter, D.; Jenner, P.; Clark, J. B.; Marsden, C. D. Mitochondrial complex I deficiency in Parkinson's disease. Lancet 1: 1269; 1989. (Pubitemid 19140359)
-
(1989)
Lancet
, vol.1
, Issue.8649
, pp. 1269
-
-
Schapira, A.H.V.1
Cooper, J.M.2
Dexter, D.3
Jenner, P.4
Clark, J.B.5
Marsden, C.D.6
-
112
-
-
0026718086
-
Skeletal muscle and platelet homogenate mitochondrial function in Parkinson's disease
-
Mann, V. M.; Cooper, J. M.; Krige, D.; Daniel, S. E.; Schapira, A. H.; Brain, Marsden C. D. skeletal muscle and platelet homogenate mitochondrial function in Parkinson's disease. Brain 115(Pt 2): 333-342; 1992.
-
(1992)
Brain
, vol.115
, Issue.PART 2
, pp. 333-342
-
-
Mann, V.M.1
Cooper, J.M.2
Krige, D.3
Daniel, S.E.4
Schapira, A.H.5
Marsden, C.D.6
-
113
-
-
67349122601
-
Human brain cortex: Mitochondrial oxidative damage and adaptive response in Parkinson disease and in dementia with Lewy bodies
-
Navarro, A.; Boveris, A.; Bandez, M. J.; Sanchez-Pino, M. J.; Gomez, C.; Muntane, G., et al. Human brain cortex: mitochondrial oxidative damage and adaptive response in Parkinson disease and in dementia with Lewy bodies. Free Radic. Biol. Med 46: 1574-1580; 2009.
-
(2009)
Free Radic. Biol. Med
, vol.46
, pp. 1574-1580
-
-
Navarro, A.1
Boveris, A.2
Bandez, M.J.3
Sanchez-Pino, M.J.4
Gomez, C.5
Muntane, G.6
-
114
-
-
33646948530
-
Parkinson's disease brain mitochondrial complex I has oxidatively damaged subunits and is functionally impaired and misassembled
-
DOI 10.1523/JNEUROSCI.0984-06.2006
-
Keeney, P. M.; Xie, J.; Capaldi, R. A.; Bennett Jr. J. P. Parkinson's disease brain mitochondrial complex I has oxidatively damaged subunits and is functionally impaired and misassembled. J. Neurosci 26: 5256-5264; 2006. (Pubitemid 44315308)
-
(2006)
Journal of Neuroscience
, vol.26
, Issue.19
, pp. 5256-5264
-
-
Keeney, P.M.1
Xie, J.2
Capaldi, R.A.3
Bennett Jr., J.P.4
-
115
-
-
34547673497
-
Peroxynitrite: Biochemistry, pathophysiology and development of therapeutics
-
DOI 10.1038/nrd2222, PII NRD2222
-
Szabo, C.; Ischiropoulos, H.; Radi, R. Peroxynitrite: biochemistry, pathophy-siology and development of therapeutics. Nat. Rev. Drug Discovery 6: 662-680; 2007. (Pubitemid 47207751)
-
(2007)
Nature Reviews Drug Discovery
, vol.6
, Issue.8
, pp. 662-680
-
-
Szabo, C.1
Ischiropoulos, H.2
Radi, R.3
-
116
-
-
56249113963
-
Inhibition of mitochondrial respiratory complex i by nitric oxide, peroxynitrite and S-nitrosothiols
-
Brown, G. C.; Borutaite, V. Inhibition of mitochondrial respiratory complex I by nitric oxide, peroxynitrite and S-nitrosothiols. Biochim. Biophys. Acta 44-49: 2004; 1658.
-
(2004)
Biochim. Biophys. Acta
, vol.44-49
, pp. 1658
-
-
Brown, G.C.1
Borutaite, V.2
-
117
-
-
76949108822
-
The role of dopamine oxidation in mitochondrial dysfunction: Implications for Parkinson's disease
-
Hastings, T. G. The role of dopamine oxidation in mitochondrial dysfunction: implications for Parkinson's disease. J. Bioenerg. Biomembr 41: 469-472; 2009.
-
(2009)
J. Bioenerg. Biomembr
, vol.41
, pp. 469-472
-
-
Hastings, T.G.1
-
118
-
-
1842612454
-
Dopamine neurons release transmitter via a flickering fusion pore
-
DOI 10.1038/nn1205
-
Staal, R. G.; Mosharov, E. V.; Sulzer, D. Dopamine neurons release transmitter via a flickering fusion pore. Nat. Neurosci. 7: 341-346; 2004. (Pubitemid 38429173)
-
(2004)
Nature Neuroscience
, vol.7
, Issue.4
, pp. 341-346
-
-
Staal, R.G.W.1
Mosharov, E.V.2
Sulzer, D.3
-
119
-
-
44649122740
-
Altered vesicular dopamine storage in Parkinson's disease: A premature demise
-
Caudle, W. M.; Colebrooke, R. E.; Emson, P. C.; Miller, G. W. Altered vesicular dopamine storage in Parkinson's disease: a premature demise. Trends Neurosci. 31: 303-308; 2008.
-
(2008)
Trends Neurosci
, vol.31
, pp. 303-308
-
-
Caudle, W.M.1
Colebrooke, R.E.2
Emson, P.C.3
Miller, G.W.4
-
120
-
-
33748502763
-
Alpha-Synuclein overexpression increases cytosolic catecholamine concentration
-
DOI 10.1523/JNEUROSCI.0519-06.2006
-
Mosharov, E. V.; Staal, R. G.; Bove, J.; Prou, D.; Hananiya, A.; Markov, D., et al. a-Synuclein overexpression increases cytosolic catecholamine concentration. J. Neurosci. 26: 9304-9311; 2006. (Pubitemid 44359856)
-
(2006)
Journal of Neuroscience
, vol.26
, Issue.36
, pp. 9304-9311
-
-
Mosharov, E.V.1
Staal, R.G.W.2
Bove, J.3
Prou, D.4
Hananiya, A.5
Markov, D.6
Poulsen, N.7
Larsen, K.E.8
Moore, C.M.H.9
Troyer, M.D.10
Edwards, R.H.11
Przedborski, S.12
Sulzer, D.13
-
121
-
-
0032914318
-
Monoamine oxidase: From genes to behavior
-
DOI 10.1146/annurev.neuro.22.1.197
-
Shih, J. C.; Chen, K.; Ridd, M. J. Monoamine oxidase: from genes to behavior. Annu. Rev. Neurosci. 22: 197-217; 1999. (Pubitemid 29144886)
-
(1999)
Annual Review of Neuroscience
, vol.22
, pp. 197-217
-
-
Shih, J.C.1
Chen, K.2
Ridd, M.J.3
-
122
-
-
0033559008
-
Cytotoxic and genotoxic potential of dopamine
-
DOI 10.1002/(SICI)1097-4547(19990315)55:6<659::AID-JNR1>3.0.CO;2-C
-
Stokes, A. H.; Hastings, T. G.; Vrana, K. E. Cytotoxic and genotoxic potential of dopamine. J. Neurosci. Res. 55: 659-665; 1999. (Pubitemid 29173480)
-
(1999)
Journal of Neuroscience Research
, vol.55
, Issue.6
, pp. 659-665
-
-
Stokes, A.H.1
Hastings, T.G.2
Vrana, K.E.3
-
123
-
-
33749170166
-
Cytosolic catechols inhibit alpha-synuclein aggregation and facilitate the formation of intracellular soluble oligomeric intermediates
-
DOI 10.1523/JNEUROSCI.0896-06.2006
-
Mazzulli, J. R.; Mishizen, A. J.; Giasson, B. I.; Lynch, D. R.; Thomas, S. A.; Nakashima, A., et al. Cytosolic catechols inhibit a-synuclein aggregation and facilitate the formation of intracellular soluble oligomeric intermediates. J. Neurosci 26: 10068-10078; 2006. (Pubitemid 44477168)
-
(2006)
Journal of Neuroscience
, vol.26
, Issue.39
, pp. 10068-10078
-
-
Mazzulli, J.R.1
Mishizen, A.J.2
Giasson, B.I.3
Lynch, D.R.4
Thomas, S.A.5
Nakashima, A.6
Nagatsu, T.7
Ota, A.8
Ischiropoulos, H.9
-
124
-
-
30744443484
-
Dopamine covalently modifies and functionally inactivates parkin
-
DOI 10.1038/nm1314, PII NM1314
-
LaVoie, M. J.; Ostaszewski, B. L.; Weihofen, A.; Schlossmacher, M. G.; Selkoe, D. J. Dopamine covalently modifies and functionally inactivates parkin. Nat. Med 11 : 1214-1221; 2005. (Pubitemid 43093669)
-
(2005)
Nature Medicine
, vol.11
, Issue.11
, pp. 1214-1221
-
-
LaVoie, M.J.1
Ostaszewski, B.L.2
Weihofen, A.3
Schlossmacher, M.G.4
Selkoe, D.J.5
-
125
-
-
67349280174
-
Proteomic identification of dopamine-conjugated proteins from isolated rat brain mitochondria and SH-SY5Y cells
-
Van Laar, V. S.; Mishizen, A. J.; Cascio, M.; Hastings, T. G. Proteomic identification of dopamine-conjugated proteins from isolated rat brain mitochondria and SH-SY5Y cells. Neurobiol. Dis 34: 487-500; 2009.
-
(2009)
Neurobiol. Dis
, vol.34
, pp. 487-500
-
-
Van Laar, V.S.1
Mishizen, A.J.2
Cascio, M.3
Hastings, T.G.4
-
126
-
-
0032842040
-
Tyrosine hydroxylase is inactivated by catechol-quinones and converted to a redox-cycling quinoprotein: Possible relevance to Parkinson's disease
-
DOI 10.1046/j.1471-4159.1999.0731309.x
-
Kuhn, D. M.; Arthur Jr. R. E.; Thomas, D. M.; Elferink, L. A. Tyrosine hydroxylase is inactivated by catechol-quinones and converted to a redox-cycling quinoprotein: possible relevance to Parkinson's disease. J. Neurochem 73: 1309-1317; 1999. (Pubitemid 29395493)
-
(1999)
Journal of Neurochemistry
, vol.73
, Issue.3
, pp. 1309-1317
-
-
Kuhn, D.M.1
Arthur Jr., R.E.2
Thomas, D.M.3
Elferink, L.A.4
-
127
-
-
0035834360
-
Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct
-
DOI 10.1126/science.1063522
-
Conway, K. A.; Rochet, J. C.; Bieganski, R. M.; Lansbury Jr. P. T. Kinetic stabilization of the a-synuclein protofibril by a dopamine-a-synuclein adduct. Science 294: 1346-1349; 2001. (Pubitemid 33063102)
-
(2001)
Science
, vol.294
, Issue.5545
, pp. 1346-1349
-
-
Conway, K.A.1
Rochet, J.-C.2
Bieganski, R.M.3
Lansbury Jr., P.T.4
-
128
-
-
33749548502
-
Overexpression of alpha-synuclein following methamphetamine: Is it good or bad?
-
DOI 10.1196/annals.1369.019, Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity: Cocaine, GHB, and Substituted Amphetamines
-
Mauceli, G.; Busceti, C. I.; Pellegrini, A.; Soldani, P.; Lenzi, P.; Paparelli, A., et al. Overexpression of a-synuclein following methamphetamine: is it good or bad? Ann. N. Y. Acad. Sci. 1074: 191-197; 2006. (Pubitemid 44532824)
-
(2006)
Annals of the New York Academy of Sciences
, vol.1074
, pp. 191-197
-
-
Mauceli, G.1
Busceti, C.I.2
Pellegrini, A.3
Soldani, P.4
Lenzi, P.5
Paparelli, A.6
Fornai, F.7
-
129
-
-
0036278335
-
Dopamine-dependent neurotoxicity of alpha-synuclein: A mechanism for selective neurodegeneration in Parkinson disease
-
DOI 10.1038/nm0602-600
-
Xu, J.; Kao, S. Y.; Lee, F. J.; Song, W.; Jin, L. W.; Yankner, B. A. Dopamine-dependent neurotoxicity of a-synuclein: a mechanism for selective neuro-degeneration in Parkinson disease. Nat. Med 8: 600-606; 2002. (Pubitemid 34633438)
-
(2002)
Nature Medicine
, vol.8
, Issue.6
, pp. 600-606
-
-
Xu, J.1
Kao, S.-Y.2
Lee, F.J.S.3
Song, W.4
Jin, L.-W.5
Yankner, B.A.6
-
130
-
-
0035066885
-
Direct binding and functional coupling of alpha-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis
-
DOI 10.1096/fj.00-0334com
-
Lee, F. J.; Liu, F.; Pristupa, Z. B.; Niznik, H. B. Direct binding and functional coupling of a-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis. FASEB J 15: 916-926; 2001. (Pubitemid 32290778)
-
(2001)
FASEB Journal
, vol.15
, Issue.6
, pp. 916-926
-
-
Lee, F.J.S.1
Liu, F.2
Pristupa, Z.B.3
Niznik, H.B.4
-
131
-
-
33745485179
-
Dopaminergic neurons reduced to silence by oxidative stress: An early step in the death cascade in Parkinson's disease?
-
Michel, P. P.; Ruberg, M.; Hirsch, E. Dopaminergic neurons reduced to silence by oxidative stress: an early step in the death cascade in Parkinson's disease? Sci. STKE 2006 :e19; 2006.
-
(2006)
Sci. STKE
, vol.2006
-
-
Michel, P.P.1
Ruberg, M.2
Hirsch, E.3
-
132
-
-
0037378026
-
Oxidative stress in Parkinson's disease
-
Jenner, P. Oxidative stress in Parkinson's disease. Ann. Neurol. 53(Suppl. 3): S26-S36; 2003.
-
(2003)
Ann. Neurol
, vol.53
, Issue.SUPPL. 3
-
-
Jenner, P.1
-
133
-
-
2442636348
-
Parkinsons-divergent causes convergent mechanisms
-
DOI 10.1126/science.1098966
-
Greenamyre, J. T.; Hastings, T. G. Parkinson's - divergent causes, convergent mechanisms. Science 304: 1120 -1122; 2004. (Pubitemid 38661838)
-
(2004)
Science
, vol.304
, Issue.5674
, pp. 1120-1122
-
-
Greenamyre, J.T.1
Hastings, T.G.2
-
134
-
-
33744500234
-
Neuroprotective properties of memantine in different in vitro and in vivo models of excitotoxicity
-
DOI 10.1111/j.1460-9568.2006.04787.x
-
Volbracht, C.; van, B. J.; Zhu, C.; Blomgren, K.; Leist, M. Neuroprotective properties of memantine in different in vitro and in vivo models of excitotoxicity. Eur. J. Neurosci 23: 2611-2622; 2006. (Pubitemid 43801453)
-
(2006)
European Journal of Neuroscience
, vol.23
, Issue.10
, pp. 2611-2622
-
-
Volbracht, C.1
Van Beek, J.2
Zhu, C.3
Blomgren, K.4
Leist, M.5
-
135
-
-
0026082060
-
+ neurotoxicity by N-methyl-D-aspartate antagonists
-
Turski, L.; Bressler, K.; Rettig, K. J.; Loschmann, P. A.; Wachtel, H. Protection of substantia nigra from MPP+ neurotoxicity by N-methyl-D-aspartate antagonists. Nature 349: 414-418; 1991. (Pubitemid 21926101)
-
(1991)
Nature
, vol.349
, Issue.6308
, pp. 414-418
-
-
Turski, L.1
Bressler, K.2
Rettig, K.-J.3
Loschmann, P.-A.4
Wachtel, H.5
-
136
-
-
0026752794
-
MK-801 prevents 1-"methyl-4-phenyl-1, 2, 3,6-tetrahydropyridine- induced parkinsonism in primates
-
Zuddas, A.; Oberto, G.; Vaglini, F.; Fascetti, F.; Fornai, F.; Corsini, G. U. MK-801 prevents 1-"methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in primates. J. Neurochem. 59: 733-739; 1992.
-
(1992)
J. Neurochem
, vol.59
, pp. 733-739
-
-
Zuddas, A.1
Oberto, G.2
Vaglini, F.3
Fascetti, F.4
Fornai, F.5
Corsini, G.U.6
-
137
-
-
0026704416
-
Partial protective effect of MK-801 on MPTP-induced reduction of striatal dopamine in mice
-
Tabatabaei, A.; Perry, T. L.; Hansen, S.; Krieger, C. Partial protective effect of MK-801 on MPTP-induced reduction of striatal dopamine in mice. Neurosci. Lett 141: 192-194; 1992.
-
(1992)
Neurosci. Lett
, vol.141
, pp. 192-194
-
-
Tabatabaei, A.1
Perry, T.L.2
Hansen, S.3
Krieger, C.4
-
138
-
-
0027515957
-
NMDA antagonists partially protect against MPTP induced neurotoxicity in mice
-
Brouillet, E.; Beal, M. F. NMDA antagonists partially protect against MPTP induced neurotoxicity in mice. Neuroreport 4: 387-390; 1993. (Pubitemid 23116729)
-
(1993)
NeuroReport
, vol.4
, Issue.4
, pp. 387-390
-
-
Brouillet, E.1
Beal, M.F.2
-
140
-
-
0035067196
-
Glutamatergic influences on the basal ganglia
-
DOI 10.1097/00002826-200103000-00001
-
Greenamyre, J. T. Glutamatergic influences on the basal ganglia. Clin. Neuropharmacol. 24: 65-70; 2001. (Pubitemid 32294680)
-
(2001)
Clinical Neuropharmacology
, vol.24
, Issue.2
, pp. 65-70
-
-
Greenamyre, J.T.1
-
141
-
-
0025319665
-
Role of calcium ions in regulation of mammalian intramitochondrial metabolism
-
McCormack, J. G.; Halestrap, A. P.; Denton, R. M. Role of calcium ions in regulation of mammalian intramitochondrial metabolism. Physiol. Rev. 70: 391-425; 1990. (Pubitemid 20140186)
-
(1990)
Physiological Reviews
, vol.70
, Issue.2
, pp. 391-425
-
-
McCormack, J.G.1
Halestrap, A.P.2
Denton, R.M.3
-
142
-
-
67649866121
-
Mitochondria and reactive oxygen species
-
Kowaltowski, A. J.; de Souza-Pinto, N. C.; Castilho, R. F.; Vercesi, A. E. Mitochondria and reactive oxygen species. Free Radic. Biol. Med. 47: 333-343; 2009.
-
(2009)
Free Radic. Biol. Med
, vol.47
, pp. 333-343
-
-
Kowaltowski, A.J.1
De Souza-Pinto, N.C.2
Castilho, R.F.3
Vercesi, A.E.4
-
143
-
-
0031017696
-
Altered calcium homeostasis in cells transformed by mitochondria from individuals with Parkinson's disease
-
Sheehan, J. P.; Swerdlow, R. H.; Parker, W. D.; Miller, S. W.; Davis, R. E.; Tuttle, J. B. Altered calcium homeostasis in cells transformed by mitochondria from individuals with Parkinson's disease. J. Neurochem. 68: 1221-1233 ; 1997. (Pubitemid 27086228)
-
(1997)
Journal of Neurochemistry
, vol.68
, Issue.3
, pp. 1221-1233
-
-
Sheehan, J.P.1
Swerdlow, R.H.2
Parker, W.D.3
Miller, S.W.4
Davis, R.E.5
Tuttle, J.B.6
-
144
-
-
58849086657
-
Oxidative stress involvement in a-synuclein oligomerization in Parkinson's disease cybrids
-
Esteves, A. R.; Arduino, D. M.; Swerdlow, R. H.; Oliveira, C. R.; Cardoso, S. M. Oxidative stress involvement in a-synuclein oligomerization in Parkinson's disease cybrids. Antioxid. Redox Signaling 11 : 439-448; 2009.
-
(2009)
Antioxid. Redox Signaling
, vol.11
, pp. 439-448
-
-
Esteves, A.R.1
Arduino, D.M.2
Swerdlow, R.H.3
Oliveira, C.R.4
Cardoso, S.M.5
-
145
-
-
0342368772
-
Association between early-onset Parkinson's disease and mutations in the parkin gene
-
DOI 10.1056/NEJM200005253422103
-
Lucking, C. B.; Durr, A.; Bonifati, V.; Vaughan, J.; De, M. G.; Gasser, T., et al. Association between early-onset Parkinson's disease and mutations in the parkin gene. N. Engl. J. Med. 342: 1560-1567; 2000. (Pubitemid 30340501)
-
(2000)
New England Journal of Medicine
, vol.342
, Issue.21
, pp. 1560-1567
-
-
Lucking, C.B.1
Durr, A.2
Bonifati, V.3
Vaughan, J.4
De Michele, G.5
Gasser, T.6
Harhangi, B.S.7
Meco, G.8
Denefle, P.9
Wood, N.W.10
Agid, Y.11
Brice, A.12
Nicholl, D.13
Breteler, M.M.B.14
Oostra, B.A.15
De Mari, M.16
Marconi, R.17
Filla, A.18
Bonnet, A.-M.19
Broussolle, E.20
Pollak, P.21
Rascol, O.22
Rosier, M.23
Arnould, I.24
more..
-
146
-
-
0037428241
-
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
-
DOI 10.1126/science.1077209
-
Bonifati, V.; Rizzu, P.; van Baren, M. J.; Schaap, O.; Breedveld, G. J.; Krieger, E., et al. Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science 299: 256-259; 2003. (Pubitemid 36131051)
-
(2003)
Science
, vol.299
, Issue.5604
, pp. 256-259
-
-
Bonifati, V.1
Rizzu, P.2
Van Baren, M.J.3
Schaap, O.4
Breedveld, G.J.5
Krieger, E.6
Dekker, M.C.J.7
Squitieri, F.8
Ibanez, P.9
Joosse, M.10
Van Dongen, J.W.11
Vanacore, N.12
Van Swieten, J.C.13
Brice, A.14
Meco, G.15
Van Duijn, C.M.16
Oostra, B.A.17
Heutink, P.18
-
147
-
-
2442668926
-
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
-
DOI 10.1126/science.1096284
-
Valente, E. M.; Abou-Sleiman, P. M.; Caputo, V.; Muqit, M. M.; Harvey, K.; Gispert, S., et al. Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science 304: 115 8 -1160; 2004. (Pubitemid 38661852)
-
(2004)
Science
, vol.304
, Issue.5674
, pp. 1158-1160
-
-
Valente, E.M.1
Abou-Sleiman, P.M.2
Caputo, V.3
Muqit, M.M.K.4
Harvey, K.5
Gispert, S.6
Ali, Z.7
Del Turco, D.8
Bentivoglio, A.R.9
Healy, D.G.10
Albanese, A.11
Nussbaum, R.12
Gonzalez-Maldonado, R.13
Deller, T.14
Salvi, S.15
Cortelli, P.16
Gilks, W.P.17
Latchman, D.S.18
Harvey, R.J.19
Dallapiccola, B.20
Auburger, G.21
Wood, N.W.22
more..
-
148
-
-
55849122639
-
Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis
-
Henchcliffe, C.; Beal, M. F. Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis. Nat. Clin. Pract. Neurol. 4: 600-609; 2008.
-
(2008)
Nat. Clin. Pract. Neurol
, vol.4
, pp. 600-609
-
-
Henchcliffe, C.1
Beal, M.F.2
-
149
-
-
0031990490
-
Ala30Pro mutation in the gene encoding a-synuclein in Parkinson's disease
-
Kruger, R.; Kuhn, W.; Muller, T.; Woitalla, D.; Graeber, M.; Kosel, S., et al. Ala30Pro mutation in the gene encoding a-synuclein in Parkinson's disease. Nat. Genet 18 : 106-108; 1998.
-
(1998)
Nat. Genet
, vol.18
, pp. 106-108
-
-
Kruger, R.1
Kuhn, W.2
Muller, T.3
Woitalla, D.4
Graeber, M.5
Kosel, S.6
-
150
-
-
10744230149
-
The New Mutation, E46K, of alpha-Synuclein Causes Parkinson and Lewy Body Dementia
-
DOI 10.1002/ana.10795
-
Zarranz, J. J.; Alegre, J.; Gomez-Esteban, J. C.; Lezcano, E.; Ros, R.; Ampuero, I., et al. The new mutation, E46K, of a-synuclein causes Parkinson and Lewy body dementia. Ann. Neurol. 55: 164-173; 2004. (Pubitemid 38166992)
-
(2004)
Annals of Neurology
, vol.55
, Issue.2
, pp. 164-173
-
-
Zarranz, J.J.1
Alegre, J.2
Gomez-Esteban, J.C.3
Lezcano, E.4
Ros, R.5
Ampuero, I.6
Vidal, L.7
Hoenicka, J.8
Rodriguez, O.9
Atares, B.10
Llorens, V.11
Gomez Tortosa, E.12
Del Ser, T.13
Munoz, D.G.14
De Yebenes, J.G.15
-
151
-
-
0027489773
-
Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease
-
DOI 10.1073/pnas.90.23.11282
-
Ueda, K.; Fukushima, H.; Masliah, E.; Xia, Y.; Iwai, A.; Yoshimoto, M., et al. Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease. Proc. Natl. Acad. Sci. USA 90: 11 2 8 2 -11286; 1993. (Pubitemid 23354413)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.23
, pp. 11282-11286
-
-
Ueda, K.1
Fukushima, H.2
Masliah, E.3
Xia, Y.4
Iwai, A.5
Yoshimoto, M.6
Otero, D.A.C.7
Kondo, J.8
Ihara, Y.9
Saitoh, T.10
-
152
-
-
0035951869
-
A hydrophobic stretch of 12 amino acid residues in the middle of a-synuclein is essential for filament assembly
-
Giasson, B. I.; Murray, I. V.; Trojanowski, J. Q.; Lee, V. M. A hydrophobic stretch of 12 amino acid residues in the middle of a-synuclein is essential for filament assembly. J. Biol. Chem 276: 2380-2386; 2001.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 2380-2386
-
-
Giasson, B.I.1
Murray, I.V.2
Trojanowski, J.Q.3
Lee, V.M.4
-
153
-
-
3342951965
-
Lipid rafts mediate the synaptic localization of alpha-synuclein
-
DOI 10.1523/JNEUROSCI.1594-04.2004
-
Fortin, D. L.; Troyer, M. D.; Nakamura, K.; Kubo, S.; Anthony, M. D.; Edwards, R. H. Lipid rafts mediate the synaptic localization of a-synuclein. J. Neurosci. 24: 6715-6723; 2004. (Pubitemid 38993891)
-
(2004)
Journal of Neuroscience
, vol.24
, Issue.30
, pp. 6715-6723
-
-
Fortin, D.L.1
Troyer, M.D.2
Nakamura, K.3
Kubo, S.-I.4
Anthony, M.D.5
Edwards, R.H.6
-
154
-
-
0035815115
-
Conformational properties of alpha-synuclein in its free and lipid-associated states
-
DOI 10.1006/jmbi.2001.4538
-
Eliezer, D.; Kutluay, E.; Bussell Jr. R.; Browne, G. Conformational properties of a-synuclein in its free and lipid-associated states. J. Mol. Biol 307: 10 61 -1073; 2001. (Pubitemid 33029953)
-
(2001)
Journal of Molecular Biology
, vol.307
, Issue.4
, pp. 1061-1073
-
-
Eliezer, D.1
Kutluay, E.2
Bussell Jr., R.3
Browne, G.4
-
155
-
-
0029127954
-
Characterization of a novel protein regulated during the critical period for song learning in the zebra finch
-
George, J. M.; Jin, H.; Woods, W. S.; Clayton, D. F. Characterization of a novel protein regulated during the critical period for song learning in the zebra finch. Neuron 15: 361-372; 1995.
-
(1995)
Neuron
, vol.15
, pp. 361-372
-
-
George, J.M.1
Jin, H.2
Woods, W.S.3
Clayton, D.F.4
-
156
-
-
0034077041
-
Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system
-
Abeliovich, A.; Schmitz, Y.; Farinas, I.; Choi-Lundberg, D.; Ho, W. H.; Castillo, P. E., et al. Mice lacking a-synuclein display functional deficits in
-
(2000)
Neuron
, vol.25
, Issue.1
, pp. 239-252
-
-
Abeliovich, A.1
Schmitz, Y.2
Farinas, I.3
Choi-Lundberg, D.4
Ho, W.-H.5
Castillo, P.E.6
Shinsky, N.7
Garcia Verdugo, J.M.8
Armanini, M.9
Ryan, A.10
Hynes, M.11
Phillips, H.12
Sulzer, D.13
Rosenthal, A.14
-
157
-
-
1842454976
-
Does alpha-synuclein modulate dopaminergic synaptic content and tone at the synapse?
-
DOI 10.1096/fj.03-1112rev
-
Sidhu, A.; Wersinger, C.; Vernier, P. Does a-synuclein modulate dopaminergic synaptic content and tone at the synapse? FASEB J 18: 637-647; 2004. (Pubitemid 38451786)
-
(2004)
FASEB Journal
, vol.18
, Issue.6
, pp. 637-647
-
-
Sidhu, A.1
Wersinger, C.2
Vernier, P.3
-
158
-
-
77953373923
-
Clues to how a-synuclein damages neurons in Parkinson's disease
-
Sulzer, D. Clues to how a-synuclein damages neurons in Parkinson's disease. Mov. Disord 25(Suppl. 1):S27-S31; 2010.
-
(2010)
Mov. Disord
, vol.25
, Issue.SUPPL. 1
-
-
Sulzer, D.1
-
159
-
-
20444401187
-
Reversible inhibition of alpha-synuclein fibrillization by dopaminochrome-mediated conformational alterations
-
DOI 10.1074/jbc.M412621200
-
Norris, E. H.; Giasson, B. I.; Hodara, R.; Xu, S.; Trojanowski, J. Q.; Ischiropoulos, H., et al. Reversible inhibition of a-synuclein fibrillization by dopaminochrome-mediated conformational alterations. J. Biol. Chem. 280: 21212-21219; 2005. (Pubitemid 40805683)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.22
, pp. 21212-21219
-
-
Norris, E.H.1
Giasson, B.I.2
Hodara, R.3
Xu, S.4
Trojanowski, J.Q.5
Ischiropoulos, H.6
Lee, V.M.-Y.7
-
160
-
-
0035800097
-
Vesicle permeabilization by protofibrillar alpha-synuclein: Implications for the pathogenesis and treatment of Parkinson's disease
-
DOI 10.1021/bi0102398
-
Volles, M. J.; Lee, S. J.; Rochet, J. C.; Shtilerman, M. D.; Ding, T. T.; Kessler, J. C., et al. Vesicle permeabilization by protofibrillar a-synuclein: implications for the pathogenesis and treatment of Parkinson's disease. Biochemistry 40: 7812-7819; 2001. (Pubitemid 32622972)
-
(2001)
Biochemistry
, vol.40
, Issue.26
, pp. 7812-7819
-
-
Volles, M.J.1
Lee, S.-J.2
Rochet, J.-C.3
Shtilerman, M.D.4
Ding, T.T.5
Kessler, J.C.6
Lansbury Jr., P.T.7
-
161
-
-
34247631275
-
Multiple hit hypotheses for dopamine neuron loss in Parkinson's disease
-
DOI 10.1016/j.tins.2007.03.009, PII S0166223607000707, Fifty years of dopamine research
-
Sulzer, D. Multiple hit hypotheses for dopamine neuron loss in Parkinson's disease. Trends Neurosci 30: 244-250; 2007. (Pubitemid 46667168)
-
(2007)
Trends in Neurosciences
, vol.30
, Issue.5
, pp. 244-250
-
-
Sulzer, D.1
-
162
-
-
0033607801
-
Degradation of a-synuclein by proteasome
-
Bennett, M. C.; Bishop, J. F.; Leng, Y.; Chock, P. B.; Chase, T. N.; Mouradian, M. M. Degradation of a-synuclein by proteasome. J. Biol. Chem. 274: 33855-33858; 1999.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 33855-33858
-
-
Bennett, M.C.1
Bishop, J.F.2
Leng, Y.3
Chock, P.B.4
Chase, T.N.5
Mouradian, M.M.6
-
163
-
-
0035976835
-
Alpha-Synuclein metabolism and aggregation is linked to ubiquitin-independent degradation by the proteasome
-
DOI 10.1016/S0014-5793(01)03115-5, PII S0014579301031155
-
Tofaris, G. K.; Layfield, R.; Spillantini, M. G. a-Synuclein metabolism and aggregation is linked to ubiquitin-independent degradation by the protea-some. FEBS Lett 509: 22-26; 2001. (Pubitemid 33153074)
-
(2001)
FEBS Letters
, vol.509
, Issue.1
, pp. 22-26
-
-
Tofaris, G.K.1
Layfield, R.2
Spillantini, M.G.3
-
164
-
-
0034884622
-
Proteasomal inhibition leads to formation of ubiquitin/alpha-synuclein- immunoreactive inclusions in PC12 cells
-
DOI 10.1046/j.1471-4159.2001.00474.x
-
Rideout, H. J.; Larsen, K. E.; Sulzer, D.; Stefanis, L. Proteasomal inhibition leads to formation of ubiquitin/a-synuclein-immunoreactive inclusions in PC12 cells. J. Neurochem 78: 899-908; 2001. (Pubitemid 32777990)
-
(2001)
Journal of Neurochemistry
, vol.78
, Issue.4
, pp. 899-908
-
-
Rideout, H.J.1
Larsen, K.E.2
Sulzer, D.3
Stefanis, L.4
-
165
-
-
0036432029
-
Proteasomal inhibition-induced inclusion formation and death in cortical neurons require transcription and ubiquitination
-
DOI 10.1006/mcne.2002.1173
-
Rideout, H. J.; Stefanis, L. Proteasomal inhibition-induced inclusion formation and death in cortical neurons require transcription and ubiquitination. Mol. Cell. Neurosci 21: 223-238; 2002. (Pubitemid 35333814)
-
(2002)
Molecular and Cellular Neuroscience
, vol.21
, Issue.2
, pp. 223-238
-
-
Rideout, H.J.1
Stefanis, L.2
-
166
-
-
0035887860
-
Induction of alpha-synuclein aggregation by intracellular nitrative insult
-
Paxinou, E.; Chen, Q.; Weisse, M.; Giasson, B. I.; Norris, E. H.; Rueter, S. M., et al. Induction of a-synuclein aggregation by intracellular nitrative insult. J. Neurosci. 21: 8053-8061; 2001. (Pubitemid 32952762)
-
(2001)
Journal of Neuroscience
, vol.21
, Issue.20
, pp. 8053-8061
-
-
Paxinou, E.1
Chen, Q.2
Weisse, M.3
Giasson, B.I.4
Norris, E.H.5
Rueter, S.M.6
Trojanowski, J.Q.7
Lee, V.M.-Y.8
Ischiropoulos, H.9
-
167
-
-
0041589248
-
Alpha-synuclein Is Degraded by Both Autophagy and the Proteasome
-
DOI 10.1074/jbc.M300227200
-
Webb, J. L.; Ravikumar, B.; Atkins, J.; Skepper, J. N.; Rubinsztein, D. C. a-Synuclein is degraded by both autophagy and the proteasome. J. Biol. Chem. 278: 25009-25013; 2003. (Pubitemid 37548663)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.27
, pp. 25009-25013
-
-
Webb, J.L.1
Ravikumar, B.2
Atkins, J.3
Skepper, J.N.4
Rubinsztein, D.C.5
-
168
-
-
1442275729
-
Clearance of alpha-Synuclein Oligomeric Intermediates via the Lysosomal Degradation Pathway
-
DOI 10.1523/JNEUROSCI.3809-03.2004
-
Lee, H. J.; Khoshaghideh, F.; Patel, S.; Lee, S. J. Clearance of a-synuclein oligomeric intermediates via the lysosomal degradation pathway. J. Neurosci 24: 1888-1896; 2004. (Pubitemid 38292800)
-
(2004)
Journal of Neuroscience
, vol.24
, Issue.8
, pp. 1888-1896
-
-
Lee, H.-J.1
Khoshaghideh, F.2
Patel, S.3
Lee, S.-J.4
-
169
-
-
70350630733
-
The emerging role of autophagy in Parkinson's disease
-
Cheung, Z. H.; Ip, N. Y. The emerging role of autophagy in Parkinson's disease. Mol. Brain 2: 29; 2009.
-
(2009)
Mol. Brain
, vol.2
, pp. 29
-
-
Cheung, Z.H.1
Ip, N.Y.2
-
170
-
-
4344659685
-
Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy
-
DOI 10.1126/science.1101738
-
Cuervo, A. M.; Stefanis, L.; Fredenburg, R.; Lansbury, P. T.; Sulzer, D. Impaired degradation of mutant a-synuclein by chaperone-mediated autophagy. Science 305: 1292-1295; 2004. (Pubitemid 39129234)
-
(2004)
Science
, vol.305
, Issue.5688
, pp. 1292-1295
-
-
Cuervo, A.M.1
Stafanis, L.2
Fredenburg, R.3
Lansbury, P.T.4
Sulzer, D.5
-
171
-
-
0037137702
-
Parkin protects against the toxicity associated with mutant alpha-Synuclein: Proteasome dysfunction selectively affects catecholaminergic neurons
-
DOI 10.1016/S0896-6273(02)01125-X
-
Petrucelli, L.; O'Farrell, C.; Lockhart, P. J.; Baptista, M.; Kehoe, K.; Vink, L., et al. Parkin protects against the toxicity associated with mutant a-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons. Neuron 36: 1007-1019; 20 02. (Pubitemid 36044504)
-
(2002)
Neuron
, vol.36
, Issue.6
, pp. 1007-1019
-
-
Petrucelli, L.1
O'Farrell, C.2
Lockhart, P.J.3
Baptista, M.4
Kehoe, K.5
Vink, L.6
Choi, P.7
Wolozin, B.8
Farrer, M.9
Hardy, J.10
Cookson, M.R.11
-
172
-
-
0038413759
-
Aggregated and monomeric alpha-synuclein bind to the S60 proteasomal protein and inhibit proteasomal function
-
DOI 10.1074/jbc.M208641200
-
Snyder, H.; Mensah, K.; Theisler, C.; Lee, J.; Matouschek, A.; Wolozin, B. Aggregated and monomeric a-synuclein bind to the S60 proteasomal protein and inhibit proteasomal function. J. Biol. Chem 278: 11753-11759; 2003. (Pubitemid 36800143)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.14
, pp. 11753-11759
-
-
Snyder, H.1
Mensah, K.2
Theisler, C.3
Lee, J.4
Matouschek, A.5
Wolozin, B.6
-
173
-
-
0035870881
-
Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis
-
Tanaka, Y.; Engelender, S.; Igarashi, S.; Rao, R. K.; Wanner, T.; Tanzi, R. E., et al. Inducible expression of mutant a-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis. Hum. Mol. Genet 10: 919-926; 2001. (Pubitemid 32401408)
-
(2001)
Human Molecular Genetics
, vol.10
, Issue.9
, pp. 919-926
-
-
Tanaka, Y.1
Engelender, S.2
Igarashi, S.3
Rao, R.K.4
Wanner, T.5
Tanzi, R.E.6
Sawa, A.7
Dawson, V.L.8
Dawson, T.M.9
Ross, C.A.10
-
174
-
-
53049098471
-
Wild type a-synuclein is degraded by chaperone-mediated autophagy and macroautophagy in neuronal cells
-
Vogiatzi, T.; Xilouri, M.; Vekrellis, K.; Stefanis, L. Wild type a-synuclein is degraded by chaperone-mediated autophagy and macroautophagy in neuronal cells. J. Biol. Chem 283: 23542-23556; 2008.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 23542-23556
-
-
Vogiatzi, T.1
Xilouri, M.2
Vekrellis, K.3
Stefanis, L.4
-
175
-
-
0033825627
-
Oxidative stress and genetics in the pathogenesis of Parkinson's disease
-
Zhang, Y.; Dawson, V. L.; Dawson, T. M. Oxidative stress and genetics in the pathogenesis of Parkinson's disease. Neurobiol. Dis 7: 240-250; 2000.
-
(2000)
Neurobiol. Dis
, vol.7
, pp. 240-250
-
-
Zhang, Y.1
Dawson, V.L.2
Dawson, T.M.3
-
176
-
-
0032879452
-
Role of cytochrome c as a stimulator of a-synuclein aggregation in Lewy body disease
-
Hashimoto, M.; Takeda, A.; Hsu, L. J.; Takenouchi, T.; Masliah, E. Role of cytochrome c as a stimulator of a-synuclein aggregation in Lewy body disease. J. Biol. Chem 274: 28849-28852; 1999.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 28849-28852
-
-
Hashimoto, M.1
Takeda, A.2
Hsu, L.J.3
Takenouchi, T.4
Masliah, E.5
-
177
-
-
33947513592
-
Pesticide exposure exacerbates alpha-synucleinopathy in an A53T transgenic mouse model
-
DOI 10.2353/ajpath.2007.060359
-
Norris, E. H.; Uryu, K.; Leight, S.; Giasson, B. I.; Trojanowski, J. Q.; Lee, V. M. Pesticide exposure exacerbates a-synucleinopathy in an A53T transgenic mouse model. Am. J. Pathol. 170: 658-666; 2007. (Pubitemid 47339402)
-
(2007)
American Journal of Pathology
, vol.170
, Issue.2
, pp. 658-666
-
-
Norris, E.H.1
Uryu, K.2
Leight, S.3
Giasson, B.I.4
Trojanowski, J.Q.5
Lee, V.M.-Y.6
-
178
-
-
0037127197
-
The herbicide paraquat causes up-regulation and aggregation of alpha-synuclein in mice: Paraquat and alpha-synuclein
-
DOI 10.1074/jbc.C100560200
-
Manning-Bog, A. B.; McCormack, A. L.; Li, J.; Uversky, V. N.; Fink, A. L.; Di Monte, D. A. The herbicide paraquat causes up-regulation and aggregation of a-synu-clein in mice: paraquat and a-synuclein. J. Biol. Chem 277: 16 41 -1644; 2002. (Pubitemid 34968732)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.3
, pp. 1641-1644
-
-
Manning-Bog, A.B.1
McCormack, A.L.2
Li, J.3
Uversky, V.N.4
Fink, A.L.5
Di Monte, D.A.6
-
179
-
-
0037195109
-
Resistance of alpha-synuclein null mice to the parkinsonian neurotoxin MPTP
-
DOI 10.1073/pnas.172514599
-
Dauer, W.; Kholodilov, N.; Vila, M.; Trillat, A. C.; Goodchild, R.; Larsen, K. E., et al. Resistance of a-synuclein null mice to the parkinsonian neurotoxin MPTP. Proc. Natl. Acad. Sci. USA 99: 14524-14529; 2002. (Pubitemid 35257704)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.22
, pp. 14524-14529
-
-
Dauer, W.1
Kholodilov, N.2
Vila, M.3
Trillat, A.-C.4
Goodchild, R.5
Larsen, K.E.6
Staal, R.7
Tieu, K.8
Schmitz, Y.9
Yuan, C.A.10
Rocha, M.11
Jackson-Lewis, V.12
Hersch, S.13
Sulzer, D.14
Przedborski, S.15
Burke, R.16
Hen, R.17
-
180
-
-
73449099224
-
Oxidants induce alternative splicing of a-synuclein: Implications for Parkinson's disease
-
Kalivendi, S. V.; Yedlapudi, D.; Hillard, C. J.; Kalyanaraman, B. Oxidants induce alternative splicing of a-synuclein: implications for Parkinson's disease. Free Radic. Biol. Med. 48: 377-383; 2010.
-
(2010)
Free Radic. Biol. Med
, vol.48
, pp. 377-383
-
-
Kalivendi, S.V.1
Yedlapudi, D.2
Hillard, C.J.3
Kalyanaraman, B.4
-
181
-
-
44049099669
-
Mitochondrial import and accumulation of a-synuclein impair complex i in human dopaminergic neuronal cultures and Parkinson disease brain
-
Devi, L.; Raghavendran, V.; Prabhu, B. M.; Avadhani, N. G.; Anandatheertha-varada, H. K. Mitochondrial import and accumulation of a-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain. J. Biol. Chem 283: 9089-9100; 2008.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 9089-9100
-
-
Devi, L.1
Raghavendran, V.2
Prabhu, B.M.3
Avadhani, N.G.4
Anandatheertha-Varada, H.K.5
-
182
-
-
44749085250
-
Mitochondrial translocation of a-synuclein is promoted by intracellular acidification
-
Cole, N. B.; Dieuliis, D.; Leo, P.; Mitchell, D. C.; Nussbaum, R. L. Mitochondrial translocation of a-synuclein is promoted by intracellular acidification. Exp. Cell Res. 314: 2076-2089; 2008.
-
(2008)
Exp. Cell Res
, vol.314
, pp. 2076-2089
-
-
Cole, N.B.1
Dieuliis, D.2
Leo, P.3
Mitchell, D.C.4
Nussbaum, R.L.5
-
183
-
-
44649150145
-
Mitochondrial localization of a-synuclein protein in a-synuclein overexpressing cells
-
Shavali, S.; Brown-Borg, H. M.; Ebadi, M.; Porter, J. Mitochondrial localization of a-synuclein protein in a-synuclein overexpressing cells. Neurosci. Lett 439: 125-128; 2008.
-
(2008)
Neurosci. Lett
, vol.439
, pp. 125-128
-
-
Shavali, S.1
Brown-Borg, H.M.2
Ebadi, M.3
Porter, J.4
-
184
-
-
68949151944
-
A-synuclein overexpression and aggregation exacerbates impairment of mitochondrial functions by augmenting oxidative stress in human neuro-blastoma cells
-
Parihar, M. S.; Parihar, A.; Fujita, M.; Hashimoto, M.; Ghafourifar, P. a-Synuclein overexpression and aggregation exacerbates impairment of mitochondrial functions by augmenting oxidative stress in human neuro-blastoma cells. Int. J. Biochem. Cell Biol 41: 2015-2024; 2009.
-
(2009)
Int. J. Biochem. Cell Biol
, vol.41
, pp. 2015-2024
-
-
Parihar, M.S.1
Parihar, A.2
Fujita, M.3
Hashimoto, M.4
Ghafourifar, P.5
-
185
-
-
30644471051
-
Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death
-
DOI 10.1523/JNEUROSCI.4308-05.2006
-
Martin, L. J.; Pan, Y.; Price, A. C.; Sterling, W.; Copeland, N. G.; Jenkins, N. A., et al. Parkinson's disease a-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death. J. Neurosci 26: 41-50; 2006. (Pubitemid 43089519)
-
(2006)
Journal of Neuroscience
, vol.26
, Issue.1
, pp. 41-50
-
-
Martin, L.J.1
Pan, Y.2
Price, A.C.3
Sterling, W.4
Copeland, N.G.5
Jenkins, N.A.6
Price, D.L.7
Lee, M.K.8
-
186
-
-
42449095464
-
Mito-chondrial association of a-synuclein causes oxidative stress
-
Parihar, M. S.; Parihar, A.; Fujita, M.; Hashimoto, M.; Ghafourifar, P. Mito-chondrial association of a-synuclein causes oxidative stress. Cell. Mol. Life Sci. 65: 1272-1284; 2008.
-
(2008)
Cell. Mol. Life Sci
, vol.65
, pp. 1272-1284
-
-
Parihar, M.S.1
Parihar, A.2
Fujita, M.3
Hashimoto, M.4
Ghafourifar, P.5
-
187
-
-
43149107699
-
Functional mitochondria are required for a-synuclein toxicity in aging yeast
-
Buttner, S.; Bitto, A.; Ring, J.; Augsten, M.; Zabrocki, P.; Eisenberg, T., et al. Functional mitochondria are required for a-synuclein toxicity in aging yeast. J. Biol. Chem 283: 7554-7560; 2008.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 7554-7560
-
-
Buttner, S.1
Bitto, A.2
Ring, J.3
Augsten, M.4
Zabrocki, P.5
Eisenberg, T.6
-
188
-
-
33749570292
-
Phosphorylation of Ser-129 is the dominant pathological modification of alpha-synuclein in familial and sporadic lewy body disease
-
DOI 10.1074/jbc.M600933200
-
Anderson, J. P.; Walker, D. E.; Goldstein, J. M.; de, L. R.; Banducci, K.; Caccavello, R. J., et al. Phosphorylation of Ser-129 is the dominant pathological modification of a-synuclein in familial and sporadic Lewy body disease. J. Biol. Chem 281: 29739-29752; 2006. (Pubitemid 44536983)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.40
, pp. 29739-29752
-
-
Anderson, J.P.1
Walker, D.E.2
Goldstein, J.M.3
De Laat, R.4
Banducci, K.5
Caccavello, R.J.6
Barbour, R.7
Huang, J.8
Kling, K.9
Lee, M.10
Diep, L.11
Keim, P.S.12
Shen, X.13
Chataway, T.14
Schlossmacher, M.G.15
Seubert, P.16
Schenk, D.17
Sinha, S.18
Gai, W.P.19
Chilcote, T.J.20
more..
-
189
-
-
0031941058
-
Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies
-
Baba, M.; Nakajo, S.; Tu, P. H.; Tomita, T.; Nakaya, K.; Lee, V. M., et al. Aggregation of a-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies. Am. J. Pathol 152: 879-884; 1998. (Pubitemid 28173348)
-
(1998)
American Journal of Pathology
, vol.152
, Issue.4
, pp. 879-884
-
-
Baba, M.1
Nakajo, S.2
Tu, P.-H.3
Tomita, T.4
Nakaya, K.5
Lee, V.M.-Y.6
Trojanowski, J.Q.7
Iwatsubo, T.8
-
190
-
-
0036174010
-
A-Synuclein is phosphorylated in synucleinopathy lesions
-
Fujiwara, H.; Hasegawa, M.; Dohmae, N.; Kawashima, A.; Masliah, E.; Goldberg, M. S., et al. a-Synuclein is phosphorylated in synucleinopathy lesions. Nat. Cell Biol. 4: 160-164; 2002.
-
(2002)
Nat. Cell Biol
, vol.4
, pp. 160-164
-
-
Fujiwara, H.1
Hasegawa, M.2
Dohmae, N.3
Kawashima, A.4
Masliah, E.5
Goldberg, M.S.6
-
191
-
-
0034602442
-
Oxidative damage linked to neurodegeneration by selective a-synuclein nitration in synucleinopathy lesions
-
Giasson, B. I.; Duda, J. E.; Murray, I. V.; Chen, Q.; Souza, J. M.; Hurtig, H. I., et al. Oxidative damage linked to neurodegeneration by selective a-synuclein nitration in synucleinopathy lesions. Science 290: 985-989; 2000.
-
(2000)
Science
, vol.290
, pp. 985-989
-
-
Giasson, B.I.1
Duda, J.E.2
Murray, I.V.3
Chen, Q.4
Souza, J.M.5
Hurtig, H.I.6
-
192
-
-
2242472974
-
Phosphorylated alpha-synuclein is ubiquitinated in alpha-synucleinopathy lesions
-
DOI 10.1074/jbc.M208046200
-
Hasegawa, M.; Fujiwara, H.; Nonaka, T.; Wakabayashi, K.; Takahashi, H.; Lee, V. M., et al. Phosphorylated a-synuclein is ubiquitinated in a-synucleinopathy lesions. J. Biol. Chem. 277: 49071-49076; 2002. (Pubitemid 35470880)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.50
, pp. 49071-49076
-
-
Hasegawa, M.1
Fujiwara, H.2
Nonaka, T.3
Wakabayashi, K.4
Takahashi, H.5
Lee, V.M.-Y.6
Trojanowski, J.Q.7
Mann, D.8
Iwatsubo, T.9
-
193
-
-
0242666359
-
Ubiquitination of alpha-Synuclein in Lewy Bodies Is a Pathological Event Not Associated with Impairment of Proteasome Function
-
DOI 10.1074/jbc.M308041200
-
Tofaris, G. K.; Razzaq, A.; Ghetti, B.; Lilley, K. S.; Spillantini, M. G. Ubiquitination of a-synuclein in Lewy bodies is a pathological event not associated with impairment of proteasome function. J. Biol. Chem 278: 44405-44411; 2003. (Pubitemid 37377190)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.45
, pp. 44405-44411
-
-
Tofaris, G.K.1
Razzaq, A.2
Ghetti, B.3
Lilley, K.S.4
Spillantini, M.G.5
-
194
-
-
50049104725
-
Phenotype genotype and worldwide genetic penetrance of lrrk2-associated parkinson's disease: A case-control study
-
Healy, D. G.; Falchi, M.; O'Sullivan, S. S.; Bonifati, V.; Durr, A.; Bressman, S., et al. Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study. Lancet Neurol 7: 583-590; 2008.
-
(2008)
Lancet Neurol
, vol.7
, pp. 583-590
-
-
Healy, D.G.1
Falchi, M.2
O'Sullivan, S.S.3
Bonifati, V.4
Durr, A.5
Bressman, S.6
-
195
-
-
33646151866
-
LRRK2 in Parkinson's disease: Protein domains and functional insights
-
Mata, I. F.; Wedemeyer, W. J.; Farrer, M. J.; Taylor, J. P.; Gallo, K. A. LRRK2 in Parkinson's disease: protein domains and functional insights. Trends Neurosci. 29: 286-293; 2006.
-
(2006)
Trends Neurosci
, vol.29
, pp. 286-293
-
-
Mata, I.F.1
Wedemeyer, W.J.2
Farrer, M.J.3
Taylor, J.P.4
Gallo, K.A.5
-
197
-
-
47749114984
-
The parkinson disease-associated leucine-rich repeat kinase 2 (lrrk2) is a dimer that undergoes intramolecular autophosphorylation
-
Greggio, E.; Zambrano, I.; Kaganovich, A.; Beilina, A.; Taymans, J. M.; Daniels, V., et al. The Parkinson disease-associated leucine-rich repeat kinase 2 (LRRK2) is a dimer that undergoes intramolecular autophosphorylation. J. Biol. Chem 283: 16906-16914; 2008.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 16906-16914
-
-
Greggio, E.1
Zambrano, I.2
Kaganovich, A.3
Beilina, A.4
Taymans, J.M.5
Daniels, V.6
-
198
-
-
51949090816
-
Phosphorylation of 4E-BP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila
-
Imai, Y.; Gehrke, S.; Wang, H. Q.; Takahashi, R.; Hasegawa, K.; Oota, E., et al. Phosphorylation of 4E-BP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila. EMBO J 27: 2432-2443; 2008.
-
(2008)
EMBO J
, vol.27
, pp. 2432-2443
-
-
Imai, Y.1
Gehrke, S.2
Wang, H.Q.3
Takahashi, R.4
Hasegawa, K.5
Oota, E.6
-
199
-
-
34447118788
-
LRRK2 phosphorylates moesin at threonine-558: Characterization of how Parkinson's disease mutants affect kinase activity
-
DOI 10.1042/BJ20070209
-
Jaleel, M.; Nichols, R. J.; Deak, M.; Campbell, D. G.; Gillardon, F.; Knebel, A., et al. LRRK2 phosphorylates moesin at threonine-558: characterization of how Parkinson's disease mutants affect kinase activity. Biochem. J 405: 307-317; 2007. (Pubitemid 47075166)
-
(2007)
Biochemical Journal
, vol.405
, Issue.2
, pp. 307-317
-
-
Jaleel, M.1
Nichols, R.J.2
Deak, M.3
Campbell, D.G.4
Gillardon, F.5
Knebel, A.6
Alessi, D.R.7
-
200
-
-
28044460070
-
Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity
-
DOI 10.1073/pnas.0507360102
-
West, A. B.; Moore, D. J.; Biskup, S.; Bugayenko, A.; Smith, W. W.; Ross, C. A., et al. Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity. Proc. Natl. Acad. Sci. USA 102 : 16 8 4 2-16847; 2005. (Pubitemid 41688864)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.46
, pp. 16842-16847
-
-
West, A.B.1
Moore, D.J.2
Biskup, S.3
Bugayenko, A.4
Smith, W.W.5
Ross, C.A.6
Dawson, V.L.7
Dawson, T.M.8
-
201
-
-
34548604567
-
The Parkinson's disease-associated protein, leucine-rich repeat kinase 2 (LRRK2), is an authentic GTPase thatstimulates kinase activity
-
DOI 10.1016/j.yexcr.2007.07.007, PII S0014482707003345
-
Guo, L.; Gandhi, P. N.; Wang, W.; Petersen, R. B.; Wilson-Delfosse, A. L.; Chen, S. G. The Parkinson's disease-associated protein, leucine-rich repeat kinase 2 (LRRK2), is an authentic GTPase that stimulates kinase activity. Exp. Cell Res 313: 3658-3670; 2007. (Pubitemid 47404550)
-
(2007)
Experimental Cell Research
, vol.313
, Issue.16
, pp. 3658-3670
-
-
Guo, L.1
Gandhi, P.N.2
Wang, W.3
Petersen, R.B.4
Wilson-Delfosse, A.L.5
Chen, S.G.6
-
202
-
-
33846818834
-
GTP binding is essential to the protein kinase activity of LRRK2, a causative gene product for familial Parkinson's disease
-
DOI 10.1021/bi061960m
-
Ito, G.; Okai, T.; Fujino, G.; Takeda, K.; Ichijo, H.; Katada, T., et al. GTP binding is essential to the protein kinase activity of LRRK2, a causative gene product for familial Parkinson's disease. Biochemistry 46: 1380-1388; 2007. (Pubitemid 46208485)
-
(2007)
Biochemistry
, vol.46
, Issue.5
, pp. 1380-1388
-
-
Ito, G.1
Okai, T.2
Fujino, G.3
Takeda, K.4
Ichijo, H.5
Katada, T.6
Iwatsubo, T.7
-
203
-
-
79958740737
-
Converging environmental and genetic pathways in the pathogenesis of Parkinson's disease
-
Burbulla, L. F.; Kruger, R. Converging environmental and genetic pathways in the pathogenesis of Parkinson's disease. J. Neurol. Sci 306: 1-8; 2011.
-
(2011)
J. Neurol. Sci
, vol.306
, pp. 1-8
-
-
Burbulla, L.F.1
Kruger, R.2
-
204
-
-
33748993710
-
Kinase activity of mutant LRRK2 mediates neuronal toxicity
-
DOI 10.1038/nn1776, PII NN1776
-
Smith, W. W.; Pei, Z.; Jiang, H.; Dawson, V. L.; Dawson, T. M.; Ross, C. A. Kinase activity of mutant LRRK2 mediates neuronal toxicity. Nat. Neurosci. 9: 1231-1233; 2006. (Pubitemid 44454261)
-
(2006)
Nature Neuroscience
, vol.9
, Issue.10
, pp. 1231-1233
-
-
Smith, W.W.1
Pei, Z.2
Jiang, H.3
Dawson, V.L.4
Dawson, T.M.5
Ross, C.A.6
-
205
-
-
19944431081
-
A frequent LRRK2 gene mutation associated with autosomal dominant Parkinson's disease
-
DOI 10.1016/S0140-6736(05)17829-5, PII S0140673605178295
-
Di, F. A.; Rohe, C. F.; Ferreira, J.; Chien, H. F.; Vacca, L.; Stocchi, F., et al. A frequent LRRK2 gene mutation associated with autosomal dominant Parkinson's disease. Lancet 365: 412-415; 2005. (Pubitemid 40179228)
-
(2005)
Lancet
, vol.365
, Issue.9457
, pp. 412-415
-
-
Di Fonzo, A.1
Rohe, C.F.2
Ferreira, J.3
Chien, H.F.4
Vacca, L.5
Stocchi, F.6
Guedes, L.7
Fabrizio, E.8
Manfredi, M.9
Vanacore, N.10
Goldwurm, S.11
Breedveld, G.12
Sampaio, C.13
Meco, G.14
Barbosa, E.15
Oostra, B.A.16
Bonifati, V.17
-
206
-
-
19944432921
-
A common LRRK2 mutation in idiopathic Parkinson's disease
-
DOI 10.1016/S0140-6736(05)17830-1, PII S0140673605178301
-
Gilks, W. P.; Abou-Sleiman, P. M.; Gandhi, S.; Jain, S.; Singleton, A.; Lees, A. J., et al. A common LRRK2 mutation in idiopathic Parkinson's disease. Lancet 365: 415-416; 2005. (Pubitemid 40179229)
-
(2005)
Lancet
, vol.365
, Issue.9457
, pp. 415-416
-
-
Gilks, W.P.1
Abou-Sleiman, P.M.2
Gandhi, S.3
Jain, S.4
Singleton, A.5
Lees, A.J.6
Shaw, K.7
Bhatia, K.P.8
Bonifati, V.9
Quinn, N.P.10
Lynch, J.11
Healy, D.G.12
Holton, J.L.13
Revesz, T.14
Wood, N.W.15
-
207
-
-
19944432606
-
Genetic screening for a single common LRRK2 mutation in familial Parkinson's disease
-
DOI 10.1016/S0140-6736(05)17828-3, PII S0140673605178283
-
Nichols, W. C.; Pankratz, N.; Hernandez, D.; Paisan-Ruiz, C.; Jain, S.; Halter, C. A., et al. Genetic screening for a single common LRRK2 mutation in familial Parkinson's disease. Lancet 365: 410-412; 2005. (Pubitemid 40179227)
-
(2005)
Lancet
, vol.365
, Issue.9457
, pp. 410-412
-
-
Nichols, W.C.1
Pankratz, N.2
Hernandez, D.3
Paisan-Ruiz, C.4
Jain, S.5
Halter, C.A.6
Michaels, V.E.7
Reed, T.8
Rudolph, A.9
Shults, C.W.10
Singleton, A.11
Foroud, T.12
-
208
-
-
32044432395
-
Biochemical and pathological characterization of Lrrk2
-
DOI 10.1002/ana.20791
-
Giasson, B. I.; Covy, J. P.; Bonini, N. M.; Hurtig, H. I.; Farrer, M. J.; Trojanowski, J. Q., et al. Biochemical and pathological characterization of Lrrk2. Ann. Neurol. 59: 315-322; 2006. (Pubitemid 43202485)
-
(2006)
Annals of Neurology
, vol.59
, Issue.2
, pp. 315-322
-
-
Giasson, B.I.1
Covy, J.P.2
Bonini, N.M.3
Hurtig, H.I.4
Farrer, M.J.5
Trojanowski, J.Q.6
Van Deerlin, V.M.7
-
209
-
-
32044466285
-
Lrrk2 and Lewy body disease
-
DOI 10.1002/ana.20731
-
Ross, O. A.; Toft, M.; Whittle, A. J.; Johnson, J. L.; Papapetropoulos, S.; Mash, D. C., et al. Lrrk2 and Lewy body disease. Ann. Neurol. 59: 388-393; 2006. (Pubitemid 43202496)
-
(2006)
Annals of Neurology
, vol.59
, Issue.2
, pp. 388-393
-
-
Ross, O.A.1
Toft, M.2
Whittle, A.J.3
Johnson, J.L.4
Papapetropoulos, S.5
Mash, D.C.6
Litvan, I.7
Gordon, M.F.8
Wszolek, Z.K.9
Farrer, M.J.10
Dickson, D.W.11
-
210
-
-
77953090478
-
Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of a-synuclein, and apoptotic cell death in aged mice
-
Tong, Y.; Yamaguchi, H.; Giaime, E.; Boyle, S.; Kopan, R.; Kelleher III R. J., et al. Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of a-synuclein, and apoptotic cell death in aged mice. Proc. Natl. Acad. Sci. USA 107: 9879-9884; 2010.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 9879-9884
-
-
Tong, Y.1
Yamaguchi, H.2
Giaime, E.3
Boyle, S.4
Kopan, R.5
Kelleher III, R.J.6
-
211
-
-
78650025189
-
Mitochondrial impairment in patients with parkinson disease with the g2019s mutation in lrrk2
-
Mortiboys, H.; Johansen, K. K.; Aasly, J. O.; Bandmann, O. Mitochondrial impairment in patients with Parkinson disease with the G2019S mutation in LRRK2. Neurology 75: 2017-2020; 2010.
-
(2010)
Neurology
, vol.75
, pp. 2017-2020
-
-
Mortiboys, H.1
Johansen, K.K.2
Aasly, J.O.3
Bandmann, O.4
-
212
-
-
79952172335
-
Lrrk2 mutant ipsc-derived da neurons demonstrate increased susceptibility to oxidative stress
-
Nguyen, H. N.; Byers, B.; Cord, B.; Shcheglovitov, A.; Byrne, J.; Gujar, P., et al. LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress. Cell Stem Cell 8: 267-280; 2011.
-
(2011)
Cell Stem Cell
, vol.8
, pp. 267-280
-
-
Nguyen, H.N.1
Byers, B.2
Cord, B.3
Shcheglovitov, A.4
Byrne, J.5
Gujar, P.6
-
213
-
-
33748351613
-
PINK1 homozygous W437X mutation in a patient with apparent dominant transmission of Parkinsonism
-
DOI 10.1002/mds.20933
-
Criscuolo, C.; Volpe, G.; De, R. A.; Varrone, A.; Marongiu, R.; Mancini, P., et al. PINK1 homozygous W437X mutation in a patient with apparent dominant transmission of parkinsonism. Mov. Disord 21: 1265-1267; 2006. (Pubitemid 44336626)
-
(2006)
Movement Disorders
, vol.21
, Issue.8
, pp. 1265-1267
-
-
Criscuolo, C.1
Volpe, G.2
De Rosa, A.3
Varrone, A.4
Marongiu, R.5
Mancini, P.6
Salvatore, E.7
Dallapiccola, B.8
Filla, A.9
Valente, E.M.10
De Michele, G.11
-
214
-
-
0035845715
-
Pseudo-dominant inheritance and exon 2 triplication in a family with parkin gene mutations
-
Lucking, C. B.; Bonifati, V.; Periquet, M.; Vanacore, N.; Brice, A.; Meco, G. Pseudo-dominant inheritance and exon 2 triplication in a family with parkin gene mutations. Neurology 57: 924-927; 2001. (Pubitemid 32845526)
-
(2001)
Neurology
, vol.57
, Issue.5
, pp. 924-927
-
-
Lucking, C.B.1
Bonifati, V.2
Periquet, M.3
Vanacore, N.4
Brice, A.5
Meco, G.6
-
215
-
-
0033868381
-
Novel mutations, pseudo-dominant inheritance, and possible familial affects in patients with autosomal recessive juvenile parkinsonism
-
DOI 10.1002/1531-8249(200008)48:2<245::AID-ANA15>3.0.CO;2-2
-
Maruyama, M.; Ikeuchi, T.; Saito, M.; Ishikawa, A.; Yuasa, T.; Tanaka, H., et al. Novel mutations, pseudo-dominant inheritance, and possible familial affects in patients with autosomal recessive juvenile parkinsonism. Ann. Neurol 48: 245-250; 2000. (Pubitemid 30617044)
-
(2000)
Annals of Neurology
, vol.48
, Issue.2
, pp. 245-250
-
-
Maruyama, M.1
Ikeuchi, T.2
Saito, M.3
Ishikawa, A.4
Yuasa, T.5
Tanaka, H.6
Hayashi, S.7
Wakabayashi, K.8
Takahashi, H.9
Tsuji, S.10
-
216
-
-
0042922470
-
Coding polymorphisms in the parkin gene and susceptibility to Parkinson disease
-
DOI 10.1001/archneur.60.9.1253
-
Lucking, C. B.; Chesneau, V.; Lohmann, E.; Verpillat, P.; Dulac, C.; Bonnet, A. M., et al. Coding polymorphisms in the parkin gene and susceptibility to Parkinson disease. Arch. Neurol 60: 1253-1256; 2003. (Pubitemid 37099631)
-
(2003)
Archives of Neurology
, vol.60
, Issue.9
, pp. 1253-1256
-
-
Lucking, C.-B.1
Chesneau, V.2
Lohmann, E.3
Verpillat, P.4
Dulac, C.5
Bonnet, A.-M.6
Gasparini, F.7
Agid, Y.8
Durr, A.9
Brice, A.10
-
217
-
-
0037648357
-
Parkin mutations are frequent in patients with isolated early-onset parkinsonism
-
DOI 10.1093/brain/awg136
-
Periquet, M.; Latouche, M.; Lohmann, E.; Rawal, N.; De, M. G.; Ricard, S., et al. Parkin mutations are frequent in patients with isolated early-onset parkin-sonism. Brain 126: 1271-1278; 2003. (Pubitemid 36644374)
-
(2003)
Brain
, vol.126
, Issue.6
, pp. 1271-1278
-
-
Periquet, M.1
Latouche, M.2
Lohmann, E.3
Rawal, N.4
De Michele, G.5
Ricard, S.6
Teive, H.7
Fraix, V.8
Vidailhet, M.9
Nicholl, D.10
Barone, P.11
Wood, N.W.12
Raskin, S.13
Deleuze, J.-F.14
Agid, Y.15
Durr, A.16
Brice, A.17
Bonnet, A.-M.18
Borg, M.19
Broussolle, E.20
Damier, Ph.21
Destee, A.22
Durif, F.23
Feingold, J.24
Fenelon, G.25
Martinez, M.26
Penet, C.27
Pollak, P.28
Rascol, O.29
Tison, F.30
Tranchant, C.31
Verin, M.32
Viallet, F.33
Warter, J.-M.34
Gasser, T.35
Muller-Myhsok, B.36
Breteler, M.37
Harhangi, S.38
Oostra, B.39
Bonifati, V.40
Vanacore, N.41
Fabrizio, E.42
Filla, A.43
Meco, G.44
more..
-
218
-
-
0028198309
-
Familial juvenile parkinsonism: Clinical and pathologic study in a family
-
Takahashi, H.; Ohama, E.; Suzuki, S.; Horikawa, Y.; Ishikawa, A.; Morita, T., et al. Familial juvenile parkinsonism: clinical and pathologic study in a family. Neurology 44: 437-441; 1994. (Pubitemid 24098141)
-
(1994)
Neurology
, vol.44
, Issue.I3
, pp. 437-441
-
-
Takahashi, H.1
Ohama, E.2
Suzuki, S.3
Horikawa, Y.4
Ishikawa, A.5
Morita, T.6
Tsuji, S.7
Ikuta, F.8
-
219
-
-
0034848395
-
Lewy bodies and parkinsonism in families with parkin mutations
-
DOI 10.1002/ana.1132
-
Farrer, M.; Chan, P.; Chen, R.; Tan, L.; Lincoln, S.; Hernandez, D., et al. Lewy bodies and parkinsonism in families with parkin mutations. Ann. Neurol 50: 293-300; 2001. (Pubitemid 32848731)
-
(2001)
Annals of Neurology
, vol.50
, Issue.3
, pp. 293-300
-
-
Farrer, M.1
Chan, P.2
Chen, R.3
Tan, L.4
Lincoln, S.5
Hernandez, D.6
Forno, L.7
Gwinn-Hardy, K.8
Petrucelli, L.9
Hussey, J.10
Singleton, A.11
Tanner, C.12
Hardy, J.13
Langston, J.W.14
-
220
-
-
33751267701
-
Parkin: A multifaceted ubiquitin ligase
-
DOI 10.1042/BST0340749
-
Moore, D. J. Parkin: a multifaceted ubiquitin ligase. Biochem. Soc. Trans. 34: 74 9 -753; 2006. (Pubitemid 44796412)
-
(2006)
Biochemical Society Transactions
, vol.34
, Issue.5
, pp. 749-753
-
-
Moore, D.J.1
-
221
-
-
0035854437
-
Ubiquitination of a new form of alpha-synuclein by parkin from human brain: Implications for Parkinson's disease
-
DOI 10.1126/science.1060627
-
Shimura, H.; Schlossmacher, M. G.; Hattori, N.; Frosch, M. P.; Trockenbacher, A.; Schneider, R., et al. Ubiquitination of a new form of a-synuclein by parkin from human brain: implications for Parkinson's disease. Science 293: 263-269; 2001. (Pubitemid 32694735)
-
(2001)
Science
, vol.293
, Issue.5528
, pp. 263-269
-
-
Shimura, H.1
Schlossmacher, M.G.2
Hattori, N.3
Frosch, M.P.4
Trockenbacher, A.5
Schneider, R.6
Mizuno, Y.7
Kosik, K.S.8
Selkoe, D.J.9
-
222
-
-
10744220754
-
The p38 subunit of the aminoacyl-tRNA synthetase complex is a Parkin substrate: Linking protein biosynthesis and neurodegeneration
-
Corti, O.; Hampe, C.; Koutnikova, H.; Darios, F.; Jacquier, S.; Prigent, A., et al. The p38 subunit of the aminoacyl-tRNA synthetase complex is a Parkin substrate: linking protein biosynthesis and neurodegeneration. Hum. Mol. Genet 12: 1427-1437; 2003. (Pubitemid 36758455)
-
(2003)
Human Molecular Genetics
, vol.12
, Issue.12
, pp. 1427-1437
-
-
Corti, O.1
Hampe, C.2
Koutnikova, H.3
Darios, F.4
Jacquier, S.5
Prigent, A.6
Robinson, J.-C.7
Pradier, L.8
Ruberg, M.9
Mirande, M.10
Hirsch, E.11
Rooney, T.12
Fournier, A.13
Brice, A.14
-
223
-
-
5444236802
-
Parkin-associated Parkinson's disease
-
DOI 10.1007/s00441-004-0924-4
-
von, C. R.; Dawson, V. L.; Dawson, T. M. Parkin-associated Parkinson's disease. Cell Tissue Res. 318: 17 5 -184; 2004. (Pubitemid 39362637)
-
(2004)
Cell and Tissue Research
, vol.318
, Issue.1
, pp. 175-184
-
-
Von Coelln, R.1
Dawson, V.L.2
Dawson, T.M.3
-
224
-
-
0033933048
-
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
-
DOI 10.1038/77060
-
Shimura, H.; Hattori, N.; Kubo, S.; Mizuno, Y.; Asakawa, S.; Minoshima, S., et al. Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase. Nat. Genet. 25: 302-305; 2000. (Pubitemid 30437317)
-
(2000)
Nature Genetics
, vol.25
, Issue.3
, pp. 302-305
-
-
Shimura, H.1
Hattori, N.2
Kubo, S.-I.3
Mizuno, Y.4
Asakawa, S.5
Minoshima, S.6
Shimizu, N.7
Iwai, K.8
Chiba, T.9
Tanaka, K.10
Suzuki, T.11
-
225
-
-
0034943022
-
Parkin is associated with cellular vesicles
-
DOI 10.1046/j.1471-4159.2001.00364.x
-
Kubo, S. I.; Kitami, T.; Noda, S.; Shimura, H.; Uchiyama, Y.; Asakawa, S., et al. Parkin is associated with cellular vesicles. J. Neurochem. 78: 42-54; 2001. (Pubitemid 32622587)
-
(2001)
Journal of Neurochemistry
, vol.78
, Issue.1
, pp. 42-54
-
-
Kubo, S.-I.1
Kitami, T.2
Noda, S.3
Shimura, H.4
Uchiyama, Y.5
Asakawa, S.6
Minoshima, S.7
Shimizu, N.8
Mizuno, Y.9
Hattori, N.10
-
226
-
-
7944227206
-
Ultrastructural localization of parkin in the rat brainstem, thalamus and basal ganglia
-
DOI 10.1007/s00702-004-0144-9, Parkinson's Research in Progress
-
Mouatt-Prigent, A.; Muriel, M. P.; Gu, W. J.; El Hachimi, K. H.; Lucking, C. B.; Brice, A., et al. Ultrastructural localization of parkin in the rat brainstem, thalamus and basal ganglia. J. Neural Transm. 111 : 1209-1218; 2004. (Pubitemid 39468386)
-
(2004)
Journal of Neural Transmission
, vol.111
, Issue.10-11
, pp. 1209-1218
-
-
Mouatt-Prigent, A.1
Muriel, M.-P.2
Gu, W.-J.3
El Hachimi, K.H.4
Lucking, C.B.5
Brice, A.6
Hirsch, E.C.7
-
227
-
-
0037338634
-
Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death
-
DOI 10.1093/hmg/ddg044
-
Darios, F.; Corti, O.; Lucking, C. B.; Hampe, C.; Muriel, M. P.; Abbas, N., et al. Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death. Hum. Mol. Genet 12: 517-526; 2003. (Pubitemid 36305590)
-
(2003)
Human Molecular Genetics
, vol.12
, Issue.5
, pp. 517-526
-
-
Darios, F.1
Corti, O.2
Lucking, C.B.3
Hampe, C.4
Muriel, M.-P.5
Abbas, N.6
Gu, W.-J.7
Hirsch, E.C.8
Rooney, T.9
Ruberg, M.10
Brice, A.11
-
228
-
-
0344011981
-
RING finger 1 mutations in Parkin produce altered localization of the protein
-
DOI 10.1093/hmg/ddg328
-
Cookson, M. R.; Lockhart, P. J.; McLendon, C.; O'Farrell, C.; Schlossmacher, M.; Farrer, M. J. RING finger 1 mutations in Parkin produce altered localization of the protein. Hum. Mol. Genet 12: 2957-2965; 2003. (Pubitemid 37442024)
-
(2003)
Human Molecular Genetics
, vol.12
, Issue.22
, pp. 2957-2965
-
-
Cookson, M.R.1
Lockhart, P.J.2
McLendon, C.3
O'Farrell, C.4
Schlossmacher, M.5
Farrer, M.J.6
-
229
-
-
10744227945
-
The C289G and C418R missense mutations cause rapid sequestration of human Parkin into insoluble aggregates
-
DOI 10.1016/j.nbd.2003.08.011
-
Gu, W. J.; Corti, O.; Araujo, F.; Hampe, C.; Jacquier, S.; Lucking, C. B., et al. The C289G and C418R missense mutations cause rapid sequestration of human Parkin into insoluble aggregates. Neurobiol. Dis 14: 357-364; 2003. (Pubitemid 37543515)
-
(2003)
Neurobiology of Disease
, vol.14
, Issue.3
, pp. 357-364
-
-
Gu, W.-J.1
Corti, O.2
Araujo, F.3
Hampe, C.4
Jacquier, S.5
Lucking, C.B.6
Abbas, N.7
Duyckaerts, C.8
Rooney, T.9
Pradier, L.10
Ruberg, M.11
Brice, A.12
-
230
-
-
20244370595
-
Alterations in the solubility and intracellular localization of parkin by several familial Parkinson's disease-linked point mutations
-
DOI 10.1111/j.1471-4159.2005.03023.x
-
Wang, C.; Tan, J. M.; Ho, M. W.; Zaiden, N.; Wong, S. H.; Chew, C. L., et al. Alterations in the solubility and intracellular localization of parkin by several familial Parkinson's disease-linked point mutations. J. Neurochem 93: 422-431; 2005. (Pubitemid 40547499)
-
(2005)
Journal of Neurochemistry
, vol.93
, Issue.2
, pp. 422-431
-
-
Wang, C.1
Tan, J.M.M.2
Ho, M.W.L.3
Zaiden, N.4
Siew, H.W.5
Chew, C.L.C.6
Pei, W.E.7
Tit, M.L.8
Dawson, T.M.9
Kah, L.L.10
-
231
-
-
33644778845
-
Parkin enhances mitochondrial biogenesis in proliferating cells
-
DOI 10.1093/hmg/ddl006
-
Kuroda, Y.; Mitsui, T.; Kunishige, M.; Shono, M.; Akaike, M.; Azuma, H., et al. Parkin enhances mitochondrial biogenesis in proliferating cells. Hum. Mol. Genet 15: 883-895; 2006. (Pubitemid 43338230)
-
(2006)
Human Molecular Genetics
, vol.15
, Issue.6
, pp. 883-895
-
-
Kuroda, Y.1
Mitsui, T.2
Kunishige, M.3
Shono, M.4
Akaike, M.5
Azuma, H.6
Matsumoto, T.7
-
232
-
-
2442481789
-
Mitochondrial Dysfunction and Oxidative Damage in parkin-deficient Mice
-
DOI 10.1074/jbc.M401135200
-
Palacino, J. J.; Sagi, D.; Goldberg, M. S.; Krauss, S.; Motz, C.; Wacker, M., et al. Mitochondrial dysfunction and oxidative damage in parkin-deficient mice. J. Biol. Chem. 279: 18 614 -18622; 2004. (Pubitemid 38623283)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.18
, pp. 18614-18622
-
-
Palacino, J.J.1
Sagi, D.2
Goldberg, M.S.3
Krauss, S.4
Motz, C.5
Wacker, M.6
Klose, J.7
Shen, J.8
-
233
-
-
34249946941
-
Mono- and double-mutant mouse models of Parkinson's disease display severe mitochondrial damage
-
DOI 10.1093/hmg/ddm083
-
Stichel, C. C.; Zhu, X. R.; Bader, V.; Linnartz, B.; Schmidt, S.; Lubbert, H. Mono-and double-mutant mouse models of Parkinson's disease display severe mitochondrial damage. Hum. Mol. Genet 16: 2377-2393; 2007. (Pubitemid 47514484)
-
(2007)
Human Molecular Genetics
, vol.16
, Issue.20
, pp. 2377-2393
-
-
Stichel, C.C.1
Zhu, X.-R.2
Bader, V.3
Linnartz, B.4
Schmidt, S.5
Lubbert, H.6
-
234
-
-
0037386532
-
Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants
-
DOI 10.1073/pnas.0737556100
-
Greene, J. C.; Whitworth, A. J.; Kuo, I.; Andrews, L. A.; Feany, M. B.; Pallanck, L. J. Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants. Proc. Natl. Acad. Sci. USA 10 0: 4078-4083; 2003. (Pubitemid 36418160)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.7
, pp. 4078-4083
-
-
Greene, J.C.1
Whitworth, A.J.2
Kuo, I.3
Andrews, L.A.4
Feany, M.B.5
Pallanck, L.J.6
-
235
-
-
2542560342
-
Drosophila parkin mutants have decreased mass and cell size and increased sensitivity to oxygen radical stress
-
DOI 10.1242/dev.01095
-
Pesah, Y.; Pham, T.; Burgess, H.; Middlebrooks, B.; Verstreken, P.; Zhou, Y., et al. Drosophila parkin mutants have decreased mass and cell size and increased sensitivity to oxygen radical stress. Development 131 : 2183-2194; 2004. (Pubitemid 38702049)
-
(2004)
Development
, vol.131
, Issue.9
, pp. 2183-2194
-
-
Pesah, Y.1
Pham, T.2
Burgess, H.3
Middlebrooks, B.4
Verstreken, P.5
Zhou, Y.6
Harding, M.7
Bellen, H.8
Mardon, G.9
-
236
-
-
21144449349
-
Common anti-apoptotic roles of parkin and alpha-synuclein in human dopaminergic cells
-
DOI 10.1016/j.bbrc.2005.04.124, PII S0006291X05008661
-
Machida, Y.; Chiba, T.; Takayanagi, A.; Tanaka, Y.; Asanuma, M.; Ogawa, N., et al. Common anti-apoptotic roles of parkin and a-synuclein in human dopaminergic cells. Biochem. Biophys. Res. Commun 332: 233-240; 2005. (Pubitemid 40719478)
-
(2005)
Biochemical and Biophysical Research Communications
, vol.332
, Issue.1
, pp. 233-240
-
-
Machida, Y.1
Chiba, T.2
Takayanagi, A.3
Tanaka, Y.4
Asanuma, M.5
Ogawa, N.6
Koyama, A.7
Iwatsubo, T.8
Ito, S.9
Jansen, P.H.10
Shimizu, N.11
Tanaka, K.12
Mizuno, Y.13
Hattori, N.14
-
237
-
-
70349569938
-
Parkin protects mitochondrial genome integrity and supports mitochondrial DNA repair
-
Rothfuss, O.; Fischer, H.; Hasegawa, T.; Maisel, M.; Leitner, P.; Miesel, F., et al. Parkin protects mitochondrial genome integrity and supports mitochondrial DNA repair. Hum. Mol. Genet 18: 3832-3850; 2009.
-
(2009)
Hum. Mol. Genet
, vol.18
, pp. 3832-3850
-
-
Rothfuss, O.1
Fischer, H.2
Hasegawa, T.3
Maisel, M.4
Leitner, P.5
Miesel, F.6
-
238
-
-
0035068574
-
Localization of a novel locus for autosomal recessive early-onset parkinsonism, PARK6, on human chromosome 1p35-p36
-
DOI 10.1086/319522
-
Valente, E. M.; Bentivoglio, A. R.; Dixon, P. H.; Ferraris, A.; Ialongo, T.; Frontali, M., et al. Localization of a novel locus for autosomal recessive early-onset parkinsonism, PARK6, on human chromosome 1p35-p36. Am. J. Hum. Genet. 68: 895-900; 2001. (Pubitemid 32289735)
-
(2001)
American Journal of Human Genetics
, vol.68
, Issue.4
, pp. 895-900
-
-
Valente, E.M.1
Bentivoglio, A.R.2
Dixon, P.H.3
Ferraris, A.4
Lalongo, T.5
Frontali, M.6
Albanese, A.7
Wood, N.W.8
-
239
-
-
22044432781
-
Early-onset parkinsonism associated with PINK1 mutations: Frequency, genotypes, and phenotypes
-
DOI 10.1212/01.wnl.0000167546.39375.82
-
Bonifati, V.; Rohe, C. F.; Breedveld, G. J.; Fabrizio, E.; De, M. M.; Tassorelli, C., et al. Early-onset parkinsonism associated with PINK1 mutations: frequency, genotypes, and phenotypes. Neurology 65: 87-95; 2005. (Pubitemid 40967781)
-
(2005)
Neurology
, vol.65
, Issue.1
, pp. 87-95
-
-
Bonifati, V.1
Rohe, C.F.2
Breedveld, G.J.3
Fabrizio, E.4
De Mari, M.5
Tassorelli, C.6
Tavella, A.7
Marconi, R.8
Nicholl, D.J.9
Chien, H.F.10
Fincati, E.11
Abbruzzese, G.12
Marini, P.13
De Gaetano, A.14
Horstink, M.W.15
Maat-Kievit, J.A.16
Sampaio, C.17
Antonini, A.18
Stocchi, F.19
Montagna, P.20
Toni, V.21
Guidi, M.22
Dalla Libera, A.23
Tinazzi, M.24
De Pandis, F.25
Fabbrini, G.26
Goldwurm, S.27
De Klein, A.28
Barbosa, E.29
Lopiano, L.30
Martignoni, E.31
Lamberti, P.32
Vanacore, N.33
Meco, G.34
Oostra, B.A.35
more..
-
240
-
-
33745845523
-
PINK1 mutations in sporadic early-onset Parkinson's Disease
-
DOI 10.1002/mds.20810
-
Tan, E. K.; Yew, K.; Chua, E.; Puvan, K.; Shen, H.; Lee, E., et al. PINK1 mutations in sporadic early-onset Parkinson's disease. Mov. Disord 21: 789-793; 2006. (Pubitemid 44028298)
-
(2006)
Movement Disorders
, vol.21
, Issue.6
, pp. 789-793
-
-
Tan, E.-K.1
Yew, K.2
Chua, E.3
Puvan, K.4
Shen, H.5
Lee, E.6
Puong, K.-Y.7
Zhao, Y.8
Pavanni, R.9
Wong, M.-C.10
Jamora, D.11
De Silva, D.12
Moe, K.-T.13
Woon, F.-P.14
Yuen, Y.15
Tan, L.16
-
241
-
-
7044236967
-
PARK6-linked autosomal recessive early-onset parkinsonism in Asian populations
-
Hatano, Y.; Sato, K.; Elibol, B.; Yoshino, H.; Yamamura, Y.; Bonifati, V., et al. PARK6-linked autosomal recessive early-onset parkinsonism in Asian populations. Neurology 63: 1482-1485; 2004. (Pubitemid 39426286)
-
(2004)
Neurology
, vol.63
, Issue.8
, pp. 1482-1485
-
-
Hatano, Y.1
Sato, K.2
Elibol, B.3
Yoshino, H.4
Yamamura, Y.5
Bonifati, V.6
Shinotoh, H.7
Asahina, M.8
Kobayashi, S.9
Ng, A.R.10
Rosales, R.L.11
Hassin-Baer, S.12
Shinar, Y.13
Lu, C.S.14
Chang, H.C.15
Wu-Chou, Y.H.16
Atac, F.B.17
Kobayashi, T.18
Toda, T.19
Mizuno, Y.20
Hattori, N.21
more..
-
242
-
-
33745087689
-
PINK1 protein in normal human brain and Parkinson's disease
-
Gandhi, S.; Muqit, M. M.; Stanyer, L.; Healy, D. G.; Abou-Sleiman, P. M.; Hargreaves, I., et al. PINK1 protein in normal human brain and Parkinson's disease. Brain 129: 17 2 0 -17231; 2006.
-
(2006)
Brain
, vol.129
, pp. 1720-1723
-
-
Gandhi, S.1
Muqit, M.M.2
Stanyer, L.3
Healy, D.G.4
Abou-Sleiman, P.M.5
Hargreaves, I.6
-
243
-
-
36049038504
-
Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin
-
DOI 10.1523/JNEUROSCI.0719-07.2007
-
Exner, N.; Treske, B.; Paquet, D.; Holmstrom, K.; Schiesling, C.; Gispert, S., et al. Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin. J. Neurosci 27: 12413-12418; 2007. (Pubitemid 350085485)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.45
, pp. 12413-12418
-
-
Exner, N.1
Treske, B.2
Paquet, D.3
Holmstrom, K.4
Schiesling, C.5
Gispert, S.6
Carballo-Carbajal, I.7
Berg, D.8
Hoepken, H.-H.9
Gasser, T.10
Kruger, R.11
Winklhofer, K.F.12
Vogel, F.13
Reichert, A.S.14
Auburger, G.15
Kahle, P.J.16
Schmid, B.17
Haass, C.18
-
244
-
-
33646573962
-
A 62-year-old woman with early-onset Parkinson's disease associated with the PINK1 gene deletion
-
Atsumi, M.; Li, Y.; Tomiyama, H.; Sato, K.; Hattori, N. [A 62-year-old woman with early-onset Parkinson's disease associated with the PINKi gene deletion]. Rinsho Shinkeigaku 46: 199-202; 2006. (Pubitemid 43761969)
-
(2006)
Clinical Neurology
, vol.46
, Issue.3
, pp. 199-202
-
-
Atsumi, M.1
Li, Y.2
Tomiyama, H.3
Sato, K.4
Hattori, N.5
-
245
-
-
4444274910
-
PINK1 mutations are associated with sporadic early-onset Parkinsonism
-
DOI 10.1002/ana.20256
-
Valente, E. M.; Salvi, S.; Ialongo, T.; Marongiu, R.; Elia, A. E.; Caputo, V., et al. PINK1 mutations are associated with sporadic early-onset parkinsonism. Ann. Neurol. 56: 336-341; 2004. (Pubitemid 39166552)
-
(2004)
Annals of Neurology
, vol.56
, Issue.3
, pp. 336-341
-
-
Valente, E.M.1
Salvi, S.2
Ialongo, T.3
Marongiu, R.4
Elia, A.E.5
Caputo, V.6
Romito, L.7
Albanese, A.8
Dallapiccola, B.9
Bentivoglio, A.R.10
-
246
-
-
33846288002
-
Mitochondrial dysfunction, peroxidation damage and changes in glutathione metabolism in PARK6
-
DOI 10.1016/j.nbd.2006.10.007, PII S0969996106002580
-
Hoepken, H. H.; Gispert, S.; Morales, B.; Wingerter, O.; Del, T. D.; Mulsch, A., et al. Mitochondrial dysfunction, peroxidation damage and changes in glutathione metabolism in PARK6. Neurobiol. Dis. 25: 401-411; 2007. (Pubitemid 46124020)
-
(2007)
Neurobiology of Disease
, vol.25
, Issue.2
, pp. 401-411
-
-
Hoepken, H.-H.1
Gispert, S.2
Morales, B.3
Wingerter, O.4
Del Turco, D.5
Mulsch, A.6
Nussbaum, R.L.7
Muller, K.8
Drose, S.9
Brandt, U.10
Deller, T.11
Wirth, B.12
Kudin, A.P.13
Kunz, W.S.14
Auburger, G.15
-
247
-
-
33745589773
-
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin
-
DOI 10.1038/nature04779, PII N04779
-
Clark, I. E.; Dodson, M. W.; Jiang, C.; Cao, J. H.; Huh, J. R.; Seol, J. H., et al. Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin. Nature 441: 116 2 -1166; 2006. (Pubitemid 43990738)
-
(2006)
Nature
, vol.441
, Issue.7097
, pp. 1162-1166
-
-
Clark, I.E.1
Dodson, M.W.2
Jiang, C.3
Cao, J.H.4
Huh, J.R.5
Seol, J.H.6
Yoo, S.J.7
Hay, B.A.8
Guo, M.9
-
248
-
-
26644440926
-
Wild-type PINK1 prevents basal and induced neuronal apoptosis, a protective effect abrogated by Parkinson disease-related mutations
-
DOI 10.1074/jbc.M505143200
-
Petit, A.; Kawarai, T.; Paitel, E.; Sanjo, N.; Maj, M.; Scheid, M., et al. Wild-type PINK1 prevents basal and induced neuronal apoptosis, a protective effect abrogated by Parkinson disease-related mutations. J. Biol. Chem 280: 34025-34032; 2005. (Pubitemid 41443124)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.40
, pp. 34025-34032
-
-
Petit, A.1
Kawarai, T.2
Paitel, E.3
Sanjo, N.4
Maj, M.5
Scheid, M.6
Chen, F.7
Gu, Y.8
Hasegawa, H.9
Salehi-Rad, S.10
Wang, L.11
Rogaeva, E.12
Fraser, P.13
Robinson, B.14
St. George-Hyslop, P.15
Tandon, A.16
-
249
-
-
49349087497
-
PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons
-
Wood-Kaczmar, A.; Gandhi, S.; Yao, Z.; Abramov, A. Y.; Miljan, E. A.; Keen, G., et al. PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons. PLoS One 3:e2455; 2008.
-
(2008)
PLoS One
, vol.3
-
-
Wood-Kaczmar, A.1
Gandhi, S.2
Yao, Z.3
Abramov, A.Y.4
Miljan, E.A.5
Keen, G.6
-
250
-
-
33745602748
-
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
-
DOI 10.1038/nature04788, PII N04788
-
Park, J.; Lee, S. B.; Lee, S.; Kim, Y.; Song, S.; Kim, S., et al. Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin. Nature 441: 115 7 -1161; 2 0 0 6 . (Pubitemid 43990737)
-
(2006)
Nature
, vol.441
, Issue.7097
, pp. 1157-1161
-
-
Park, J.1
Lee, S.B.2
Lee, S.3
Kim, Y.4
Song, S.5
Kim, S.6
Bae, E.7
Kim, J.8
Shong, M.9
Kim, J.-M.10
Chung, J.11
-
251
-
-
33746080412
-
Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin
-
DOI 10.1073/pnas.0602493103
-
Yang, Y.; Gehrke, S.; Imai, Y.; Huang, Z.; Ouyang, Y.; Wang, J. W., et al. Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin. Proc. Natl. Acad. Sci. USA 103: 10793-10798; 2006. (Pubitemid 44078055)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.28
, pp. 10793-10798
-
-
Yang, Y.1
Gehrke, S.2
Imai, Y.3
Huang, Z.4
Ouyang, Y.5
Wang, J.-W.6
Yang, L.7
Beal, M.F.8
Vogel, H.9
Lu, B.10
-
252
-
-
77952884442
-
Autophagy and the degradation of mitochondria
-
Goldman, S. J.; Taylor, R.; Zhang, Y.; Jin, S. Autophagy and the degradation of mitochondria. Mitochondrion 10: 309-315; 2010.
-
(2010)
Mitochondrion
, vol.10
, pp. 309-315
-
-
Goldman, S.J.1
Taylor, R.2
Zhang, Y.3
Jin, S.4
-
253
-
-
34249934085
-
Selective degradation of mitochondria by mitophagy
-
DOI 10.1016/j.abb.2007.03.034, PII S0003986107001622, Highlight Issue: Pro- and antiapoptotic Signalling
-
Kim, I.; Rodriguez-Enriquez, S.; Lemasters, J. J. Selective degradation of mitochondria by mitophagy. Arch. Biochem. Biophys. 462: 245-253; 2007. (Pubitemid 46876640)
-
(2007)
Archives of Biochemistry and Biophysics
, vol.462
, Issue.2
, pp. 245-253
-
-
Kim, I.1
Rodriguez-Enriquez, S.2
Lemasters, J.J.3
-
254
-
-
58149314211
-
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
-
Narendra, D.; Tanaka, A.; Suen, D. F.; Youle, R. J. Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J. Cell Biol 183: 795-803; 2008.
-
(2008)
J. Cell Biol
, vol.183
, pp. 795-803
-
-
Narendra, D.1
Tanaka, A.2
Suen, D.F.3
Youle, R.J.4
-
255
-
-
75749156257
-
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin
-
Narendra, D. P.; Jin, S. M.; Tanaka, A.; Suen, D. F.; Gautier, C. A.; Shen, J., et al. PINK1 is selectively stabilized on impaired mitochondria to activate Parkin. PLoS Biol. 8:e1000298; 2010.
-
(2010)
PLoS Biol
, vol.8
-
-
Narendra, D.P.1
Jin, S.M.2
Tanaka, A.3
Suen, D.F.4
Gautier, C.A.5
Shen, J.6
-
256
-
-
77951181836
-
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
-
Matsuda, N.; Sato, S.; Shiba, K.; Okatsu, K.; Saisho, K.; Gautier, C. A., et al. PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy. J. Cell Biol 18 9 : 211-221; 2010.
-
(2010)
J. Cell Biol
, vol.189
, pp. 211-221
-
-
Matsuda, N.1
Sato, S.2
Shiba, K.3
Okatsu, K.4
Saisho, K.5
Gautier, C.A.6
-
257
-
-
72749106042
-
VPS41, a protein involved in lysosomal trafficking, is protective in Caenor-habditis elegans and mammalian cellular models of Parkinson's disease
-
Ruan, Q.; Harrington, A. J.; Caldwell, K. A.; Caldwell, G. A.; Standaert, D. G. VPS41, a protein involved in lysosomal trafficking, is protective in Caenor-habditis elegans and mammalian cellular models of Parkinson's disease. Neurobiol. Dis 37: 330-338; 2010.
-
(2010)
Neurobiol. Dis
, vol.37
, pp. 330-338
-
-
Ruan, Q.1
Harrington, A.J.2
Caldwell, K.A.3
Caldwell, G.A.4
Standaert, D.G.5
-
258
-
-
55749090654
-
The parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in drosophila
-
Deng, H.; Dodson, M. W.; Huang, H.; Guo, M. The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila. Proc. Natl. Acad. Sci. USA 105: 14503-14508; 2008.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 14503-14508
-
-
Deng, H.1
Dodson, M.W.2
Huang, H.3
Guo, M.4
-
259
-
-
39449088321
-
The PINK1/Parkin pathway regulates mitochondrial morphology
-
DOI 10.1073/pnas.0709336105
-
Poole, A. C.; Thomas, R. E.; Andrews, L. A.; McBride, H. M.; Whitworth, A. J.; Pallanck, L. J. The PINK1/Parkin pathway regulates mitochondrial morphology. Proc. Natl. Acad. Sci. USA 105: 1638-1643; 2008. (Pubitemid 351346567)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.5
, pp. 1638-1643
-
-
Poole, A.C.1
Thomas, R.E.2
Andrews, L.A.3
McBride, H.M.4
Whitworth, A.J.5
Pallanck, L.J.6
-
260
-
-
68549136513
-
Differential effects of PINK1 nonsense and missense mutations on mitochondrial function and morphology
-
Grunewald, A.; Gegg, M. E.; Taanman, J. W.; King, R. H.; Kock, N.; Klein, C., et al. Differential effects of PINK1 nonsense and missense mutations on mitochondrial function and morphology. Exp. Neurol. 219: 266-273; 2009.
-
(2009)
Exp. Neurol
, vol.219
, pp. 266-273
-
-
Grunewald, A.1
Gegg, M.E.2
Taanman, J.W.3
King, R.H.4
Kock, N.5
Klein, C.6
-
261
-
-
57749100375
-
Mitochondrial function and morphology are impaired in parkin-mutant fibroblasts
-
Mortiboys, H.; Thomas, K. J.; Koopman, W. J.; Klaffke, S.; Abou-Sleiman, P.; Olpin, S., et al. Mitochondrial function and morphology are impaired in parkin-mutant fibroblasts. Ann. Neurol 64: 555-565; 2008.
-
(2008)
Ann. Neurol
, vol.64
, pp. 555-565
-
-
Mortiboys, H.1
Thomas, K.J.2
Koopman, W.J.3
Klaffke, S.4
Abou-Sleiman, P.5
Olpin, S.6
-
262
-
-
56349137588
-
Mitochondrial respiratory dysfunction in familiar parkinsonism associated with PINK1 mutation
-
Piccoli, C.; Sardanelli, A.; Scrima, R.; Ripoli, M.; Quarato, G.; D'Aprile, A., et al. Mitochondrial respiratory dysfunction in familiar parkinsonism associated with PINK1 mutation. Neurochem. Res 33: 2565-2574; 2008.
-
(2008)
Neurochem. Res
, vol.33
, pp. 2565-2574
-
-
Piccoli, C.1
Sardanelli, A.2
Scrima, R.3
Ripoli, M.4
Quarato, G.5
D'Aprile, A.6
-
263
-
-
0346434141
-
A missense mutation (L166P) in DJ-1, linked to familial Parkinson's disease, confers reduced protein stability and impairs homo-oligomerization
-
Moore, D. J.; Zhang, L.; Dawson, T. M.; Dawson, V. L. A missense mutation (L166P) in DJ-1, linked to familial Parkinson's disease, confers reduced protein stability and impairs homo-oligomerization. J. Neurochem 87: 15 5 8 -1567; 2003. (Pubitemid 38020589)
-
(2003)
Journal of Neurochemistry
, vol.87
, Issue.6
, pp. 1558-1567
-
-
Moore, D.J.1
Zhang, L.2
Dawson, T.M.3
Dawson, V.L.4
-
264
-
-
24944534660
-
Mitochondrial localization of the Parkinson's disease related protein DJ-1: Implications for pathogenesis
-
DOI 10.1093/hmg/ddi211
-
Zhang, L.; Shimoji, M.; Thomas, B.; Moore, D. J.; Yu, S. W.; Marupudi, N. I., et al. Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis. Hum. Mol. Genet 14: 2063-2073; 2005. (Pubitemid 41418042)
-
(2005)
Human Molecular Genetics
, vol.14
, Issue.14
, pp. 2063-2073
-
-
Zhang, L.1
Shimoji, M.2
Thomas, B.3
Moore, D.J.4
Yu, S.-W.5
Marupudi, N.I.6
Torp, R.7
Torgner, I.A.8
Ottersen, O.P.9
Dawson, T.M.10
Dawson, V.L.11
-
265
-
-
0031566231
-
DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras
-
DOI 10.1006/bbrc.1997.6132
-
Nagakubo, D.; Taira, T.; Kitaura, H.; Ikeda, M.; Tamai, K.; Iguchi-Ariga, S. M., et al. DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras. Biochem. Biophys. Res. Commun 231: 509-513; 1997. (Pubitemid 27214343)
-
(1997)
Biochemical and Biophysical Research Communications
, vol.231
, Issue.2
, pp. 509-513
-
-
Nagakubo, D.1
Taira, T.2
Kitaura, H.3
Ikeda, M.4
Tamai, K.5
Iguchi-Ariga, S.M.M.6
Ariga, H.7
-
266
-
-
0042232353
-
The role of pathogenic DJ-1 mutations in Parkinson's disease
-
DOI 10.1002/ana.10675
-
Abou-Sleiman, P. M.; Healy, D. G.; Quinn, N.; Lees, A. J.; Wood, N. W. The role of pathogenic DJ-1 mutations in Parkinson's disease. Ann. Neurol. 54: 283-286; 2003. (Pubitemid 37072030)
-
(2003)
Annals of Neurology
, vol.54
, Issue.3
, pp. 283-286
-
-
Abou-Sleiman, P.M.1
Healy, D.G.2
Quinn, N.3
Lees, A.J.4
Wood, N.W.5
-
267
-
-
2942684871
-
The Parkinson's disease DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization
-
DOI 10.1073/pnas.0402959101
-
Canet-Aviles, R. M.; Wilson, M. A.; Miller, D. W.; Ahmad, R.; McLendon, C.; Bandyopadhyay, S., et al. The Parkinson's disease protein DJ-1 is neuropro-tective due to cysteine-sulfinic acid-driven mitochondrial localization. Proc. Natl. Acad. Sci. USA 101: 9103-9108; 2004. (Pubitemid 38781618)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.24
, pp. 9103-9108
-
-
Canet-Aviles, R.M.1
Wilson, M.A.2
Miller, D.W.3
Ahmad, R.4
McLendon, C.5
Bandyopadhyay, S.6
Baptista, M.J.7
Ringe, D.8
Petsko, G.A.9
Cookson, M.R.10
-
268
-
-
12344251678
-
Association of DJ-1 and parkin mediated by pathogenic DJ-1 mutations and oxidative stress
-
DOI 10.1093/hmg/ddi007
-
Moore, D. J.; Zhang, L.; Troncoso, J.; Lee, M. K.; Hattori, N.; Mizuno, Y., et al. Association of DJ-1 and parkin mediated by pathogenic DJ-1 mutations and oxidative stress. Hum. Mol. Genet 14: 71-84; 2005. (Pubitemid 40123464)
-
(2005)
Human Molecular Genetics
, vol.14
, Issue.1
, pp. 71-84
-
-
Moore, D.J.1
Zhang, L.2
Troncoso, J.3
Lee, M.K.4
Hattori, N.5
Mizuno, Y.6
Dawson, T.M.7
Dawson, V.L.8
-
269
-
-
0142217556
-
DJ-1 (PARK7), a novel gene for autosomal recessive, early onset parkinsonism
-
DOI 10.1007/s10072-003-0108-0
-
Bonifati, V.; Rizzu, P.; Squitieri, F.; Krieger, E.; Vanacore, N.; van Swieten, J. C., et al. DJ-1 (PARK7), a novel gene for autosomal recessive, early onset parkinsonism. Neurol. Sci. 24: 15 9-160; 2003. (Pubitemid 37304291)
-
(2003)
Neurological Sciences
, vol.24
, Issue.3
, pp. 159-160
-
-
Bonifati, V.1
Rizzu, P.2
Squitieri, F.3
Krieger, E.4
Vanacore, N.5
Van Swieten, J.C.6
Brice, A.7
Van Duijn, C.M.8
Oostra, B.9
Meco, G.10
Heutink, P.11
-
270
-
-
1642527499
-
DJ-1 has a role in antioxidative stress to prevent cell death
-
DOI 10.1038/sj.embor.7400074
-
Taira, T.; Saito, Y.; Niki, T.; Iguchi-Ariga, S. M.; Takahashi, K.; Ariga, H. DJ-1 has a role in antioxidative stress to prevent cell death. EMBO Rep 5: 213-218; 2004. (Pubitemid 38401204)
-
(2004)
EMBO Reports
, vol.5
, Issue.2
, pp. 213-218
-
-
Taira, T.1
Saito, Y.2
Niki, T.3
Iguchi-Ariga, S.M.M.4
Takahashi, K.5
Ariga, H.6
-
271
-
-
5044235807
-
Novel homozygous p.E64D mutation in DJ1 in early onset Parkinson disease (PARK7)
-
DOI 10.1002/humu.20089
-
Hering, R.; Strauss, K. M.; Tao, X.; Bauer, A.; Woitalla, D.; Mietz, E. M., et al. Novel homozygous p.E64D mutation in DJ1 in early onset Parkinson disease (PARK7). Hum. Mutat. 24: 321-329; 2004. (Pubitemid 39336638)
-
(2004)
Human Mutation
, vol.24
, Issue.4
, pp. 321-329
-
-
Hering, R.1
Strauss, K.M.2
Tao, X.3
Bauer, A.4
Woitalla, D.5
Mietz, E.-M.6
Petrovic, S.7
Bauer, P.8
Schaible, W.9
Muller, T.10
Schols, L.11
Klein, C.12
Berg, D.13
Meyer, P.T.14
Schulz, J.B.15
Wollnik, B.16
Tong, L.17
Kruger, R.18
Riess, O.19
-
272
-
-
44649188448
-
Oxidative insults induce dj-1 upregulation and redistribution: Implications for neuroprotection
-
Lev, N.; Ickowicz, D.; Melamed, E.; Offen, D. Oxidative insults induce DJ-1 upregulation and redistribution: implications for neuroprotection. Neurotox-icology 29: 397-405; 2008.
-
(2008)
Neurotox-icology
, vol.29
, pp. 397-405
-
-
Lev, N.1
Ickowicz, D.2
Melamed, E.3
Offen, D.4
-
273
-
-
24044472010
-
Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease
-
DOI 10.1016/j.cub.2005.07.064, PII S0960982205008481
-
Meulener, M.; Whitworth, A. J.; Armstrong-Gold, C. E.; Rizzu, P.; Heutink, P.; Wes, P. D., et al. Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease. Curr. Biol 15: 1572-1577; 20 05. (Pubitemid 41219597)
-
(2005)
Current Biology
, vol.15
, Issue.17
, pp. 1572-1577
-
-
Meulener, M.1
Whitworth, A.J.2
Armstrong-Gold, C.E.3
Rizzu, P.4
Heutink, P.5
Wes, P.D.6
Pallanck, L.J.7
Bonini, N.M.8
-
274
-
-
27144519984
-
Drosophila DJ-1 mutants show oxidative stress-sensitive locomotive dysfunction
-
DOI 10.1016/j.gene.2005.06.040, PII S0378111905004336
-
Park, J.; Kim, S. Y.; Cha, G. H.; Lee, S. B.; Kim, S.; Chung, J. Drosophila DJ-1 mutants show oxidative stress-sensitive locomotive dysfunction. Gene 361: 133-139; 2005. (Pubitemid 41506941)
-
(2005)
Gene
, vol.361
, Issue.1-2
, pp. 133-139
-
-
Park, J.1
Sung, Y.K.2
Cha, G.-H.3
Sung, B.L.4
Kim, S.5
Chung, J.6
-
275
-
-
33747611218
-
Mutational analysis of DJ-1 in Drosophila implicates functional inactivation by oxidative damage and aging
-
DOI 10.1073/pnas.0601891103
-
Meulener, M. C.; Xu, K.; Thomson, L.; Ischiropoulos, H.; Bonini, N. M. Mutational analysis of DJ-1 in Drosophila implicates functional inactivation by oxidative damage and aging. Proc. Natl. Acad. Sci. USA 10 3 : 12517-12522; 2006. (Pubitemid 44267290)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.33
, pp. 12517-12522
-
-
Meulener, M.C.1
Xu, K.2
Thompson, L.3
Ischiropoulos, H.4
Bonini, N.M.5
-
276
-
-
20144389422
-
Hypersensitivity of DJ-1-deficient mice to 1-"methyl-4-phenyl-1,2, 3,6-tetrahydropyrindine (MPTP) and oxidative stress
-
Kim, R. H.; Smith, P. D.; Aleyasin, H.; Hayley, S.; Mount, M. P.; Pownall, S., et al. Hypersensitivity of DJ-1-deficient mice to 1-"methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress. Proc. Natl. Acad. Sci. USA 102: 5215-5220; 2005.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 5215-5220
-
-
Kim, R.H.1
Smith, P.D.2
Aleyasin, H.3
Hayley, S.4
Mount, M.P.5
Pownall, S.6
-
277
-
-
13944279784
-
Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: An ES-derived cell model of primary parkinsonism
-
Martinat, C.; Shendelman, S.; Jonason, A.; Leete, T.; Beal, M. F.; Yang, L., et al. Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: an ES-derived cell model of primary parkinsonism. PLoS Biol. 2:e327; 2004.
-
(2004)
PLoS Biol
, vol.2
-
-
Martinat, C.1
Shendelman, S.2
Jonason, A.3
Leete, T.4
Beal, M.F.5
Yang, L.6
-
278
-
-
13944267769
-
DJ-1 is a redox-dependent molecular chaperone that inhibits a-synuclein aggregate formation
-
Shendelman, S.; Jonason, A.; Martinat, C.; Leete, T.; Abeliovich, A. DJ-1 is a redox-dependent molecular chaperone that inhibits a-synuclein aggregate formation. PLoS Biol. 2:e362; 2004.
-
(2004)
PLoS Biol
, vol.2
-
-
Shendelman, S.1
Jonason, A.2
Martinat, C.3
Leete, T.4
Abeliovich, A.5
-
279
-
-
35748954034
-
Paraquat induces dopaminergic dysfunction and proteasome impairment in DJ-1-deficient mice
-
DOI 10.1093/hmg/ddm249
-
Yang, W.; Chen, L.; Ding, Y.; Zhuang, X.; Kang, U. J. Paraquat induces dopaminergic dysfunction and proteasome impairment in DJ-1-deficient mice. Hum. Mol. Genet 16: 2900-2910; 2007. (Pubitemid 350048387)
-
(2007)
Human Molecular Genetics
, vol.16
, Issue.23
, pp. 2900-2910
-
-
Yang, W.1
Chen, L.2
Ding, Y.3
Zhuang, X.4
Kang, U.J.5
-
280
-
-
77953363542
-
DJ-1 protects against oxidative damage by regulating the thioredoxin/ASK1 complex
-
Im, J. Y.; Lee, K. W.; Junn, E.; Mouradian, M. M. DJ-1 protects against oxidative damage by regulating the thioredoxin/ASK1 complex. Neurosci. Res 67: 203-208; 2010.
-
(2010)
Neurosci. Res
, vol.67
, pp. 203-208
-
-
Im, J.Y.1
Lee, K.W.2
Junn, E.3
Mouradian, M.M.4
-
281
-
-
70449729372
-
DJ-1 binds to mitochondrial complex i and maintains its activity
-
Hayashi, T.; Ishimori, C.; Takahashi-Niki, K.; Taira, T.; Kim, Y. C.; Maita, H., et al. DJ-1 binds to mitochondrial complex I and maintains its activity. Biochem. Biophys. Res. Commun. 390: 667-672; 2009.
-
(2009)
Biochem. Biophys. Res. Commun
, vol.390
, pp. 667-672
-
-
Hayashi, T.1
Ishimori, C.2
Takahashi-Niki, K.3
Taira, T.4
Kim, Y.C.5
Maita, H.6
-
282
-
-
77949623516
-
Reduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson's disease-associated protein DJ-1
-
Krebiehl, G.; Ruckerbauer, S.; Burbulla, L. F.; Kieper, N.; Maurer, B.; Waak, J., et al. Reduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson's disease-associated protein DJ-1. PLoS One 5:e9367; 2010.
-
(2010)
PLoS One
, vol.5
-
-
Krebiehl, G.1
Ruckerbauer, S.2
Burbulla, L.F.3
Kieper, N.4
Maurer, B.5
Waak, J.6
-
283
-
-
45549108542
-
Cellular and molecular mechanisms involved in the neurotoxicity of opioid and psychostimulant drugs
-
Cunha-Oliveira, T.; Rego, A. C.; Oliveira, C. R. Cellular and molecular mechanisms involved in the neurotoxicity of opioid and psychostimulant drugs. Brain Res. Rev 58: 192-208; 2008.
-
(2008)
Brain Res. Rev
, vol.58
, pp. 192-208
-
-
Cunha-Oliveira, T.1
Rego, A.C.2
Oliveira, C.R.3
-
285
-
-
78649350162
-
Substance abuse and movement disorders
-
Brust, J. C. Substance abuse and movement disorders. Mov. Disord 25: 2010-2020; 2010.
-
(2010)
Mov. Disord
, vol.25
, pp. 2010-2020
-
-
Brust, J.C.1
-
286
-
-
84155165436
-
Increased risk of parkinson's disease in individuals hospitalized with conditions related to the use of methamphetamine or other amphetamine-type drugs
-
Callaghan, R. C.; Cunningham, J. K.; Sykes, J.; Kish, S. J. Increased risk of Parkinson's disease in individuals hospitalized with conditions related to the use of methamphetamine or other amphetamine-type drugs. Drug Alcohol Depend 120: 35-40; 2012.
-
(2012)
Drug Alcohol Depend
, vol.120
, pp. 35-40
-
-
Callaghan, R.C.1
Cunningham, J.K.2
Sykes, J.3
Kish, S.J.4
-
287
-
-
79951702177
-
How addictive drugs disrupt presynaptic dopamine neurotrans-mission
-
Sulzer, D. How addictive drugs disrupt presynaptic dopamine neurotrans-mission. Neuron 69: 628-649; 2011.
-
(2011)
Neuron
, vol.69
, pp. 628-649
-
-
Sulzer, D.1
-
288
-
-
84866014473
-
Toxicity of amphetamines: An update
-
Carvalho, M.; Carmo, H.; Costa, V. M.; Capela, J. P.; Pontes, H.; Remiao, F., et al. Toxicity of amphetamines: an update. Arch. Toxicol. 86: 11 6 7 -1231; 2012.
-
(2012)
Arch. Toxicol
, vol.86
, pp. 1167-1231
-
-
Carvalho, M.1
Carmo, H.2
Costa, V.M.3
Capela, J.P.4
Pontes, H.5
Remiao, F.6
-
289
-
-
0031846705
-
Carrier-mediated release, transport rates, and charge transfer induced by amphetamine, tyramine, and dopamine in mammalian cells transfected with the human dopamine transporter
-
Sitte, H. H.; Huck, S.; Reither, H.; Boehm, S.; Singer, E. A.; Pifl, C. Carrier-mediated release, transport rates, and charge transfer induced by amphetamine, tyramine, and dopamine in mammalian cells transfected with the human dopamine transporter. J. Neurochem 71: 1289-1297; 1998. (Pubitemid 28390284)
-
(1998)
Journal of Neurochemistry
, vol.71
, Issue.3
, pp. 1289-1297
-
-
Sitte, H.H.1
Huck, S.2
Reither, H.3
Boehm, S.4
Singer, E.A.5
Pifl, C.6
-
290
-
-
0032734471
-
Dopamine neuronal transport kinetics and effects of amphetamine
-
Jones, S. R.; Joseph, J. D.; Barak, L. S.; Caron, M. G.; Wightman, R. M. Dopamine neuronal transport kinetics and effects of amphetamine. J. Neurochem. 73: 2406-2414; 1999.
-
(1999)
J. Neurochem
, vol.73
, pp. 2406-2414
-
-
Jones, S.R.1
Joseph, J.D.2
Barak, L.S.3
Caron, M.G.4
Wightman, R.M.5
-
291
-
-
0029032794
-
Amphetamine redistributes dopamine from synaptic vesicles to the cytosol and promotes reverse transport
-
Sulzer, D.; Chen, T. K.; Lau, Y. Y.; Kristensen, H.; Rayport, S.; Ewing, A. Amphetamine redistributes dopamine from synaptic vesicles to the cytosol and promotes reverse transport. J. Neurosci 15: 4102-4108; 1995.
-
(1995)
J. Neurosci
, vol.15
, pp. 4102-4108
-
-
Sulzer, D.1
Chen, T.K.2
Lau, Y.Y.3
Kristensen, H.4
Rayport, S.5
Ewing, A.6
-
292
-
-
14744274092
-
Amphetamine induces dopamine efflux through a dopamine transporter channel
-
DOI 10.1073/pnas.0407737102
-
Kahlig, K. M.; Binda, F.; Khoshbouei, H.; Blakely, R. D.; McMahon, D. G.; Javitch, J. A., et al. Amphetamine induces dopamine efflux through a dopamine transporter channel. Proc. Natl. Acad. Sci. USA 102 : 3495-3500; 2005. (Pubitemid 40328073)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.9
, pp. 3495-3500
-
-
Kahlig, K.M.1
Binda, F.2
Khoshbouei, H.3
Blakely, R.D.4
McMahon, D.G.5
Javitch, J.A.6
Galli, A.7
-
293
-
-
20644441994
-
Mechanisms of neurotransmitter release by amphetamines: A review
-
DOI 10.1016/j.pneurobio.2005.04.003, PII S0301008205000432
-
Sulzer, D.; Sonders, M. S.; Poulsen, N. W.; Galli, A. Mechanisms of neuro-transmitter release by amphetamines: a review. Prog. Neurobiol. 75: 406-433; 2005. (Pubitemid 40834286)
-
(2005)
Progress in Neurobiology
, vol.75
, Issue.6
, pp. 406-433
-
-
Sulzer, D.1
Sonders, M.S.2
Poulsen, N.W.3
Galli, A.4
-
294
-
-
85031067897
-
Inhibitors alter the spectrum and redox properties of monoamine oxidase
-
Ramsay, R. R.; Hunter, D. J. Inhibitors alter the spectrum and redox properties of monoamine oxidase. A. Biochim. Biophys. Acta 178-184: 2002; 1601.
-
(2002)
A. Biochim. Biophys. Acta
, vol.178-184
, pp. 1601
-
-
Ramsay, R.R.1
Hunter, D.J.2
-
295
-
-
0018146493
-
Long-term changes in dopaminergic innervation of caudate nucleus after continuous amphetamine administration
-
Ellison, G.; Eison, M. S.; Huberman, H. S.; Daniel, F. Long-term changes in dopaminergic innervation of caudate nucleus after continuous amphetamine administration. Science 201: 276-278; 1978. (Pubitemid 8396757)
-
(1978)
Science
, vol.201
, Issue.4352
, pp. 276-278
-
-
Ellison, G.1
Eison, M.S.2
Huberman, H.S.3
Daniel, F.4
-
296
-
-
28744438907
-
Differential cytotoxic responses of PC12 cells chronically exposed to psychostimulants or to hydrogen peroxide
-
DOI 10.1016/j.tox.2005.08.022, PII S0300483X05003860
-
Cunha-Oliveira, T.; Rego, A. C.; Morgadinho, M. T.; Macedo, T.; Oliveira, C. R. Differential cytotoxic responses of PC12 cells chronically exposed to psy-chostimulants or to hydrogen peroxide. Toxicology 217: 54-62; 2006. (Pubitemid 41758393)
-
(2006)
Toxicology
, vol.217
, Issue.1
, pp. 54-62
-
-
Cunha-Oliveira, T.1
Rego, A.C.2
Morgadinho, M.T.3
Macedo, T.4
Oliveira, C.R.5
-
297
-
-
0035693854
-
Is methamphetamine abuse a risk factor in Parkinsonism?
-
DOI 10.1016/S0161-813X(01)00046-8, PII S0161813X01000468
-
Guilarte, T. R. Is methamphetamine abuse a risk factor in parkinsonism? Neurotoxicology 22: 725-731; 2001. (Pubitemid 34075630)
-
(2001)
NeuroToxicology
, vol.22
, Issue.6
, pp. 725-731
-
-
Guilarte, T.R.1
-
298
-
-
10444225476
-
Study of association between alpha-synuclein gene polymorphism and methamphetamine psychosis/dependence
-
DOI 10.1196/annals.1316.040
-
Kobayashi, H.; Ide, S.; Hasegawa, J.; Ujike, H.; Sekine, Y.; Ozaki, N., et al. Study of association between a-synuclein gene polymorphism and methamphetamine psychosis/dependence. Ann. N. Y. Acad. Sci. 10 25: 325-334; 2004. (Pubitemid 39643878)
-
(2004)
Annals of the New York Academy of Sciences
, vol.1025
, pp. 325-334
-
-
Kobayashi, H.1
Ide, S.2
Hasegawa, J.3
Ujike, H.4
Sekine, Y.5
Ozaki, N.6
Inada, T.7
Harano, M.8
Komiyama, T.9
Yamada, M.10
Iyo, M.11
Shen, H.-W.12
Ikeda, K.13
Sora, I.14
-
299
-
-
10444238568
-
Similarities between methamphetamine toxicity and proteasome inhibition
-
DOI 10.1196/annals.1316.021
-
Fornai, F.; Lenzi, P.; Gesi, M.; Ferrucci, M.; Lazzeri, G.; Capobianco, L., et al. Similarities between methamphetamine toxicity and proteasome inhibition. Ann. N. Y. Acad. Sci. 1025: 162-170; 2004. (Pubitemid 39643859)
-
(2004)
Annals of the New York Academy of Sciences
, vol.1025
, pp. 162-170
-
-
Fornai, F.1
Lenzi, P.2
Gesi, M.3
Ferrucci, M.4
Lazzeri, G.5
Capobianco, L.6
De Blasi, A.7
Battaglia, G.8
Nicoletti, F.9
Ruggieri, S.10
Paparelli, A.11
-
300
-
-
33747141059
-
The neurotoxicity of amphetamines: Bridging drugs of abuse and neurodegenerative disorders
-
DOI 10.1016/j.expneurol.2006.02.130, PII S0014488606002123
-
Iacovelli, L.; Fulceri, F.; De, B. A.; Nicoletti, F.; Ruggieri, S.; Fornai, F. The neurotoxicity of amphetamines: bridging drugs of abuse and neurodegen-erative disorders. Exp. Neurol. 201: 24-31; 2006. (Pubitemid 44223465)
-
(2006)
Experimental Neurology
, vol.201
, Issue.1
, pp. 24-31
-
-
Iacovelli, L.1
Fulceri, F.2
De Blasi, A.3
Nicoletti, F.4
Ruggieri, S.5
Fornai, F.6
-
301
-
-
0037229425
-
Subcutaneous rotenone exposure causes highly selective dopaminergic degeneration and alpha-synuclein aggregation
-
DOI 10.1006/exnr.2002.8072
-
Sherer, T. B.; Kim, J. H.; Betarbet, R.; Greenamyre, J. T. Subcutaneous rotenone exposure causes highly selective dopaminergic degeneration and a-synuclein aggregation. Exp. Neurol 179: 9-16; 20 03. (Pubitemid 36062614)
-
(2003)
Experimental Neurology
, vol.179
, Issue.1
, pp. 9-16
-
-
Sherer, T.B.1
Kim, J.-H.2
Betarbet, R.3
Greenamyre, J.T.4
-
302
-
-
20044385568
-
Parkinson-like syndrome induced by continuous MPTP infusion: Convergent roles of the ubiquitin-proteasome system and alpha-synuclein
-
DOI 10.1073/pnas.0409713102
-
Fornai, F.; Schluter, O. M.; Lenzi, P.; Gesi, M.; Ruffoli, R.; Ferrucci, M., et al. Parkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiquitin-proteasome system and a-synuclein. Proc. Natl. Acad. Sci. USA 102: 3413-3418; 2005. (Pubitemid 40328059)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.9
, pp. 3413-3418
-
-
Fornai, F.1
Schluter, O.M.2
Lenzi, P.3
Gesi, M.4
Ruffoli, R.5
Ferrucci, M.6
Lazzeri, G.7
Busceti, C.L.8
Pontarelli, F.9
Battaglia, G.10
Pellegrini, A.11
Nicoletti, F.12
Ruggieri, S.13
Paparelli, A.14
Sudhof, T.C.15
-
303
-
-
20144389039
-
Occurrence of neuronal inclusions combined with increased nigral expression of a-synuclein within dopaminergic neurons following treatment with amphetamine derivatives in mice
-
Fornai, F.; Lenzi, P.; Ferrucci, M.; Lazzeri, G.; di Poggio, A. B.; Natale, G., et al. Occurrence of neuronal inclusions combined with increased nigral expression of a-synuclein within dopaminergic neurons following treatment with amphetamine derivatives in mice. Brain Res. Bull 65: 405-413; 2005.
-
(2005)
Brain Res. Bull
, vol.65
, pp. 405-413
-
-
Fornai, F.1
Lenzi, P.2
Ferrucci, M.3
Lazzeri, G.4
Di Poggio, A.B.5
Natale, G.6
-
304
-
-
0033966487
-
Alpha-synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP
-
DOI 10.1046/j.1471-4159.2000.740721.x
-
Vila, M.; Vukosavic, S.; Jackson-Lewis, V.; Neystat, M.; Jakowec, M.; Przedborski, S. a-Synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP. J. Neu-rochem 74: 721-729; 2000. (Pubitemid 30053745)
-
(2000)
Journal of Neurochemistry
, vol.74
, Issue.2
, pp. 721-729
-
-
Vila, M.1
Vukosavic, S.2
Jackson-Lewis, V.3
Neystat, M.4
Jakowec, M.5
Przedborski, S.6
-
305
-
-
77149143852
-
Potentiation of methamphetamine neurotoxicity by intrastriatal lipopolysac-charide administration
-
Jung, B. D.; Shin, E. J.; Nguyen, X. K.; Jin, C. H.; Bach, J. H.; Park, S. J., et al. Potentiation of methamphetamine neurotoxicity by intrastriatal lipopolysac-charide administration. Neurochem. Int. 56: 229-244; 2010.
-
(2010)
Neurochem. Int
, vol.56
, pp. 229-244
-
-
Jung, B.D.1
Shin, E.J.2
Nguyen, X.K.3
Jin, C.H.4
Bach, J.H.5
Park, S.J.6
-
306
-
-
33746810059
-
Amphetamine neurotoxicity: Cause and consequence of oxidative stress
-
Yamamoto, B. K.; Bankson, M. G. Amphetamine neurotoxicity: cause and consequence of oxidative stress. Crit. Rev. Neurobiol. 17: 87-117; 2005. (Pubitemid 44174002)
-
(2005)
Critical Reviews in Neurobiology
, vol.17
, Issue.2
, pp. 87-117
-
-
Yamamoto, B.K.1
Bankson, M.G.2
-
307
-
-
34548405973
-
Neurotoxicity of substituted amphetamines: Molecular and cellular mechanisms
-
Cadet, J. L.; Krasnova, I. N.; Jayanthi, S.; Lyles, J. Neurotoxicity of substituted amphetamines: molecular and cellular mechanisms. Neurotox. Res. 11 : 183-202; 2007.
-
(2007)
Neurotox. Res
, vol.11
, pp. 183-202
-
-
Cadet, J.L.1
Krasnova, I.N.2
Jayanthi, S.3
Lyles, J.4
-
308
-
-
34247211016
-
Enhanced oxidative stress and aberrant mitochondrial biogenesis in human neuroblastoma SH-SY5Y cells during methamphetamine induced apoptosis
-
Wu, C. W.; Ping, Y. H.; Yen, J. C.; Chang, C. Y.; Wang, S. F.; Yeh, C. L., et al. Enhanced oxidative stress and aberrant mitochondrial biogenesis in human neuroblastoma SH-SY5Y cells during methamphetamine induced apoptosis. Toxicol. Appl. Pharmacol. 220: 243-251; 2007.
-
(2007)
Toxicol. Appl. Pharmacol
, vol.220
, pp. 243-251
-
-
Wu, C.W.1
Ping, Y.H.2
Yen, J.C.3
Chang, C.Y.4
Wang, S.F.5
Yeh, C.L.6
-
309
-
-
15244357686
-
Free radical production induced by methamphetamine in rat striatal synaptosomes
-
DOI 10.1016/j.taap.2004.08.008
-
Pubill, D.; Chipana, C.; Camins, A.; Pallas, M.; Camarasa, J.; Escubedo, E. Free radical production induced by methamphetamine in rat striatal synapto-somes. Toxicol. Appl. Pharmacol 204: 57-68; 2005. (Pubitemid 40387567)
-
(2005)
Toxicology and Applied Pharmacology
, vol.204
, Issue.1
, pp. 57-68
-
-
Pubill, D.1
Chipana, C.2
Camins, A.3
Pallas, M.4
Camarasa, J.5
Escubedo, E.6
-
310
-
-
33745877318
-
Increased oxidative stress in submitochondrial particles after chronic amphetamine exposure
-
DOI 10.1016/j.brainres.2006.04.076, PII S000689930601153X
-
Frey, B. N.; Valvassori, S. S.; Gomes, K. M.; Martins, M. R.; Dal-Pizzol, F.; Kapczinski, F., et al. Increased oxidative stress in submitochondrial particles after chronic amphetamine exposure. Brain Res. 1097: 224-229; 2006. (Pubitemid 44041287)
-
(2006)
Brain Research
, vol.1097
, Issue.1
, pp. 224-229
-
-
Frey, B.N.1
Valvassori, S.S.2
Gomes, K.M.3
Martins, M.R.4
Dal-Pizzol, F.5
Kapczinski, F.6
Quevedo, J.7
-
311
-
-
11144354601
-
Neurotoxicity of amphetamine derivatives is mediated by caspase pathway activation in rat cerebellar granule cells
-
DOI 10.1016/j.taap.2003.12.017, PII S0041008X04000080
-
Jimenez, A.; Jorda, E. G.; Verdaguer, E.; Pubill, D.; Sureda, F. X.; Canudas, A. M., et al. Neurotoxicity of amphetamine derivatives is mediated by caspase pathway activation in rat cerebellar granule cells. Toxicol. Appl. Pharmacol 19 6 : 223-234; 2004. (Pubitemid 38469956)
-
(2004)
Toxicology and Applied Pharmacology
, vol.196
, Issue.2
, pp. 223-234
-
-
Jimenez, A.1
Jorda, E.G.2
Verdaguer, E.3
Pubill, D.4
Sureda, F.X.5
Canudas, A.M.6
Escubedo, E.7
Camarasa, J.8
Camins, A.9
Pallas, M.10
-
312
-
-
3042611829
-
Brain antioxidant systems in human methamphetamine users
-
DOI 10.1111/j.1471-4159.2004.02434.x
-
Mirecki, A.; Fitzmaurice, P.; Ang, L.; Kalasinsky, K. S.; Peretti, F. J.; Aiken, S. S., et al. Brain antioxidant systems in human methamphetamine users. J. Neurochem. 89: 13 9 6 -1408; 2004. (Pubitemid 38802661)
-
(2004)
Journal of Neurochemistry
, vol.89
, Issue.6
, pp. 1396-1408
-
-
Mirecki, A.1
Fitzmaurice, P.2
Ang, L.3
Kalasinsky, K.S.4
Peretti, F.J.5
Aiken, S.S.6
Wickham, D.J.7
Sherwin, A.8
Nobrega, J.N.9
Forman, H.J.10
Kish, S.J.11
-
313
-
-
0342955033
-
The effects of single dose of methamphetamine on lipid peroxidation levels in the rat striatum and prefrontal cortex
-
Acikgoz, O.; Gonenc, S.; Kayatekin, B. M.; Pekcetin, C.; Uysal, N.; Dayi, A., et al. The effects of single dose of methamphetamine on lipid peroxidation levels in the rat striatum and prefrontal cortex. Eur. Neuropsychopharmacol 10: 415-418; 2000.
-
(2000)
Eur. Neuropsychopharmacol
, vol.10
, pp. 415-418
-
-
Acikgoz, O.1
Gonenc, S.2
Kayatekin, B.M.3
Pekcetin, C.4
Uysal, N.5
Dayi, A.6
-
314
-
-
33745101692
-
Changes in antioxidant defense enzymes after d-amphetamine exposure: Implications as an animal model of mania
-
DOI 10.1007/s11064-006-9070-6
-
Frey, B. N.; Valvassori, S. S.; Reus, G. Z.; Martins, M. R.; Petronilho, F. C.; Bardini, K., et al. Changes in antioxidant defense enzymes after D-amphetamine exposure: implications as an animal model of mania. Neurochem. Res. 31: 699-703; 2006. (Pubitemid 43886419)
-
(2006)
Neurochemical Research
, vol.31
, Issue.5
, pp. 699-703
-
-
Frey, B.N.1
Valvassori, S.S.2
Reus, G.Z.3
Martins, M.R.4
Petronilho, F.C.5
Bardini, K.6
Dal-Pizzol, F.7
Kapczinski, F.8
Quevedo, J.9
-
315
-
-
0034927677
-
Adaptative response of antioxidant enzymes in different areas of rat brain after repeated d-amphetamine administration
-
DOI 10.1080/13556210120056544
-
Carvalho, F.; Fernandes, E.; Remiao, F.; Gomes-Da-Silva, J.; Tavares, M. A.; Bastos, M. D. Adaptative response of antioxidant enzymes in different areas of rat brain after repeated D-amphetamine administration. Addict. Biol 6: 213-221; 2001. (Pubitemid 32675402)
-
(2001)
Addiction Biology
, vol.6
, Issue.3
, pp. 213-221
-
-
Carvalho, F.1
Fernandes, E.2
Remiao, F.3
Gomes-Da-Silva, J.4
Tavares, M.A.5
Bastos, M.D.L.6
-
316
-
-
33751189188
-
Levels of 4-hydroxynonenal and malondialdehyde are increased in brain of human chronic users of methamphetamine
-
Fitzmaurice, P. S.; Tong, J.; Yazdanpanah, M.; Liu, P. P.; Kalasinsky, K. S.; Kish, S. J. Levels of 4-hydroxynonenal and malondialdehyde are increased in brain of human chronic users of methamphetamine. J. Pharmacol. Exp. Ther 319: 703-709; 2006.
-
(2006)
J. Pharmacol. Exp. Ther
, vol.319
, pp. 703-709
-
-
Fitzmaurice, P.S.1
Tong, J.2
Yazdanpanah, M.3
Liu, P.P.4
Kalasinsky, K.S.5
Kish, S.J.6
-
317
-
-
28744438907
-
Differential cytotoxic responses of PC12 cells chronically exposed to psychostimulants or to hydrogen peroxide
-
DOI 10.1016/j.tox.2005.08.022, PII S0300483X05003860
-
Cunha-Oliveira, T.; Rego, A. C.; Morgadinho, M. T.; Macedo, T.; Oliveira, C. R. Differential cytotoxic responses of PC12 cells chronically exposed to psychostimulants or to hydrogen peroxide. Toxicology 217: 54-62; 2006. (Pubitemid 41758393)
-
(2006)
Toxicology
, vol.217
, Issue.1
, pp. 54-62
-
-
Cunha-Oliveira, T.1
Rego, A.C.2
Morgadinho, M.T.3
Macedo, T.4
Oliveira, C.R.5
-
318
-
-
80053937625
-
Low concentrations of methamphetamine can protect dopaminergic cells against a larger oxidative stress injury: Mechanistic study
-
El Avadi, A.; Zigmond, M. J. Low concentrations of methamphetamine can protect dopaminergic cells against a larger oxidative stress injury: mechanistic study. PLoS One 6:e24722; 2011.)
-
(2011)
PLoS One
, vol.6
-
-
El Avadi, A.1
Zigmond, M.J.2
|