-
3
-
-
0029943449
-
Mismatch repair in replication fidelity, genetic recombination, and cancer biology
-
Modrich P, Lahue R. Mismatch repair in replication fidelity, genetic recombination, and cancer biology. Annu Rev Biochem 1996; 65:101-133.
-
(1996)
Annu Rev Biochem
, vol.65
, pp. 101-133
-
-
Modrich, P.1
Lahue, R.2
-
4
-
-
0015729624
-
Marker discrimination in transformation and mutation of pneumococcus
-
Tiraby JG, Fox MS. Marker discrimination in transformation and mutation of pneumococcus. Proc Natl Acad Sci USA 1973; 70:3541-3545.
-
(1973)
Proc Natl Acad Sci USA
, vol.70
, pp. 3541-3545
-
-
Tiraby, J.G.1
Fox, M.S.2
-
5
-
-
0032730774
-
Genetic susceptibility to non-polyposis colorectal cancer
-
Lynch HT, de la Chapelle A. Genetic susceptibility to non-polyposis colorectal cancer. J Med Genet 1999; 36:801-818.
-
(1999)
J Med Genet
, vol.36
, pp. 801-818
-
-
Lynch, H.T.1
de la Chapelle, A.2
-
6
-
-
0033290537
-
The role of mismatch repair in DNA damage-induced apoptosis
-
Li GM. The role of mismatch repair in DNA damage-induced apoptosis. Oncol Res 1999; 11: 393-400.
-
(1999)
Oncol Res
, vol.11
, pp. 393-400
-
-
Li, G.M.1
-
7
-
-
3242885728
-
Mismatch repair and DNA damage signalling
-
Stojic L, Brun R, Jiricny J. Mismatch repair and DNA damage signalling. DNA Repair (Amst) 2004; 3:1091-1101.
-
(2004)
DNA Repair (Amst)
, vol.3
, pp. 1091-1101
-
-
Stojic, L.1
Brun, R.2
Jiricny, J.3
-
9
-
-
33646187811
-
The multifaceted mismatch-repair system
-
Jiricny J. The multifaceted mismatch-repair system. Nat Rev Mol Cell Biol 2006; 7:335-346.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 335-346
-
-
Jiricny, J.1
-
10
-
-
0034734330
-
Structure and function of mismatch repair proteins
-
Yang W. Structure and function of mismatch repair proteins. Mutat Res 2000; 460:245-256.
-
(2000)
Mutat Res
, vol.460
, pp. 245-256
-
-
Yang, W.1
-
11
-
-
0242442569
-
DNA mismatch repair: Molecular mechanisms and biological function
-
Schofield MJ, Hsieh P. DNA mismatch repair: molecular mechanisms and biological function. Annu Rev Microbiol 2003; 57:579-608.
-
(2003)
Annu Rev Microbiol
, vol.57
, pp. 579-608
-
-
Schofield, M.J.1
Hsieh, P.2
-
12
-
-
0024396565
-
DNA mismatch correction in a defined system
-
Lahue RS, Au KG, Modrich P. DNA mismatch correction in a defined system. Science 1989; 245:160-164.
-
(1989)
Science
, vol.245
, pp. 160-164
-
-
Lahue, R.S.1
Au, K.G.2
Modrich, P.3
-
13
-
-
0035811037
-
In vivo requirement for RecJ, ExoVII, Exol, and ExoX in methyl-directed mismatch repair
-
Burdett V, Baitinger C, Viswanathan M, Lovett ST, Modrich P. In vivo requirement for RecJ, ExoVII, Exol, and ExoX in methyl-directed mismatch repair. Proc Natl Acad Sci USA 2001; 98:6765-6770.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 6765-6770
-
-
Burdett, V.1
Baitinger, C.2
Viswanathan, M.3
Lovett, S.T.4
Modrich, P.5
-
14
-
-
0034641938
-
Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA
-
Obmolova G, Ban C, Hsieh P, Yang W. Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA. Nature 2000; 407:703-710.
-
(2000)
Nature
, vol.407
, pp. 703-710
-
-
Obmolova, G.1
Ban, C.2
Hsieh, P.3
Yang, W.4
-
15
-
-
0034641947
-
The crystal structure of DNA mismatch repair protein MutS binding to a G*T mismatch
-
Lamers MH, Perrakis A, Enzlin JH, Winterwerp HH, de Wind N, Sixma TK. The crystal structure of DNA mismatch repair protein MutS binding to a G*T mismatch. Nature 2000; 407:711-717.
-
(2000)
Nature
, vol.407
, pp. 711-717
-
-
Lamers, M.H.1
Perrakis, A.2
Enzlin, J.H.3
Winterwerp, H.H.4
de Wind, N.5
Sixma, T.K.6
-
16
-
-
33746189409
-
Endonucleolytic function of MutLalpha in human mismatch repair
-
Kadyrov FA, Dzantiev L, Constantin N, Modrich P. Endonucleolytic function of MutLalpha in human mismatch repair. Cell 2006; 126:297-308.
-
(2006)
Cell
, vol.126
, pp. 297-308
-
-
Kadyrov, F.A.1
Dzantiev, L.2
Constantin, N.3
Modrich, P.4
-
17
-
-
0027522357
-
Molecular matchmakers
-
Sancar A, Hearst JE. Molecular matchmakers. Science 1993; 259:1415-1420.
-
(1993)
Science
, vol.259
, pp. 1415-1420
-
-
Sancar, A.1
Hearst, J.E.2
-
18
-
-
0032502779
-
Mismatch-, MutS-, MutL-, and helicase II-dependent unwinding from the single-strand break of an incised heteroduplex
-
Dao V, Modrich P. Mismatch-, MutS-, MutL-, and helicase II-dependent unwinding from the single-strand break of an incised heteroduplex. J Biol Chem 1998; 273:9202-9207.
-
(1998)
J Biol Chem
, vol.273
, pp. 9202-9207
-
-
Dao, V.1
Modrich, P.2
-
19
-
-
9144274423
-
Structure of the MutL C-terminal domain: A model of intact MutL and its roles in mismatch repair
-
Guarne A, Ramon-Maiques S, Wolff EM, et al. Structure of the MutL C-terminal domain: a model of intact MutL and its roles in mismatch repair. Embo J 2004; 23:4134-4145.
-
(2004)
Embo J
, vol.23
, pp. 4134-4145
-
-
Guarne, A.1
Ramon-Maiques, S.2
Wolff, E.M.3
-
20
-
-
0032514843
-
Crystal structure and ATPase activity of MutL: Implications for DNA repair and mutagenesis
-
Ban C, Yang W. Crystal structure and ATPase activity of MutL: implications for DNA repair and mutagenesis. Cell 1998; 95:541-552.
-
(1998)
Cell
, vol.95
, pp. 541-552
-
-
Ban, C.1
Yang, W.2
-
21
-
-
0029971935
-
Dominant negative mutator mutations in the mutL gene of Escherichia coli
-
Aronshtam A, Marinus MG. Dominant negative mutator mutations in the mutL gene of Escherichia coli. Nucleic Acids Res 1996; 24:2498-2504.
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 2498-2504
-
-
Aronshtam, A.1
Marinus, M.G.2
-
22
-
-
0035102126
-
Composite active site of an ABC ATPase: MutS uses ATP to verify mismatch recognition and authorize DNA repair
-
Junop MS, Obmolova G, Rausch K, Hsieh P, YangW. Composite active site of an ABC ATPase: MutS uses ATP to verify mismatch recognition and authorize DNA repair. Mol Cell 2001; 7:1-12.
-
(2001)
Mol Cell
, vol.7
, pp. 1-12
-
-
Junop, M.S.1
Obmolova, G.2
Rausch, K.3
Hsieh, P.4
YangW5
-
23
-
-
37249060488
-
Escherichia coli mismatch repair protein MutL interacts with the clamp loader subunits of DNA polymerase III
-
Jul 25; doi:10.1016/j.mrfmmm.2007.07.008
-
Li F, Liu Q, Chen YY, et al. Escherichia coli mismatch repair protein MutL interacts with the clamp loader subunits of DNA polymerase III. Mutat Res 2007 Jul 25; doi:10.1016/j.mrfmmm.2007.07.008.
-
(2007)
Mutat Res
-
-
Li, F.1
Liu, Q.2
Chen, Y.Y.3
-
25
-
-
0032473571
-
Structural basis for MutH activation in E.coli mismatch repair and relationship of MutH to restriction endonucleases
-
Ban C, Yang W. Structural basis for MutH activation in E.coli mismatch repair and relationship of MutH to restriction endonucleases. Embo J1998; 17:1526-1534.
-
(1998)
Embo J
, vol.17
, pp. 1526-1534
-
-
Ban, C.1
Yang, W.2
-
26
-
-
25844494491
-
MutH complexed with hemi- and unmethylated DNAs: Coupling base recognition and DNA cleavage
-
Lee JY, Chang J, Joseph N, Ghirlando R, Rao DN, Yang W. MutH complexed with hemi- and unmethylated DNAs: coupling base recognition and DNA cleavage. Mol Cell 2005; 20:155-166.
-
(2005)
Mol Cell
, vol.20
, pp. 155-166
-
-
Lee, J.Y.1
Chang, J.2
Joseph, N.3
Ghirlando, R.4
Rao, D.N.5
Yang, W.6
-
27
-
-
0036121372
-
Partial reconstitution of human DNA mismatch repair in vitro: Characterization of the role of human replication protein A
-
Ramilo C, Gu L, Guo S, et al. Partial reconstitution of human DNA mismatch repair in vitro: characterization of the role of human replication protein A. Mol Cell Biol 2002; 22:2037-2046.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 2037-2046
-
-
Ramilo, C.1
Gu, L.2
Guo, S.3
-
28
-
-
0026446241
-
Isolation and characterization of two Saccharomyces cerevisiae genes encoding homologs of the bacterial HexA and MutS mismatch repair proteins
-
Reenan RA, Kolodner RD. Isolation and characterization of two Saccharomyces cerevisiae genes encoding homologs of the bacterial HexA and MutS mismatch repair proteins. Genetics 1992; 132:963-973.
-
(1992)
Genetics
, vol.132
, pp. 963-973
-
-
Reenan, R.A.1
Kolodner, R.D.2
-
29
-
-
0027742295
-
The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer
-
Fishel R, Lescoe MK, Rao MR, et al. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell 1993; 75:1027-1038.
-
(1993)
Cell
, vol.75
, pp. 1027-1038
-
-
Fishel, R.1
Lescoe, M.K.2
Rao, M.R.3
-
30
-
-
0027145633
-
Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer
-
Leach FS, Nicolaides NC, Papadopoulos N, et al. Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell 1993; 75:1215-1225.
-
(1993)
Cell
, vol.75
, pp. 1215-1225
-
-
Leach, F.S.1
Nicolaides, N.C.2
Papadopoulos, N.3
-
31
-
-
0029008683
-
GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells
-
Palombo F, Gallinari P, Iaccarino I, et al. GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells. Science 1995; 268:1912-1914.
-
(1995)
Science
, vol.268
, pp. 1912-1914
-
-
Palombo, F.1
Gallinari, P.2
Iaccarino, I.3
-
32
-
-
0029070143
-
Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch repair to tumor cells
-
Drummond JT, Li GM, Longley MJ, Modrich P. Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch repair to tumor cells. Science 1995; 268:1909-1912.
-
(1995)
Science
, vol.268
, pp. 1909-1912
-
-
Drummond, J.T.1
Li, G.M.2
Longley, M.J.3
Modrich, P.4
-
33
-
-
0028221943
-
Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer
-
Bronner CE, Baker SM, Morrison PT, et al. Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer. Nature 1994; 368:258-261.
-
(1994)
Nature
, vol.368
, pp. 258-261
-
-
Bronner, C.E.1
Baker, S.M.2
Morrison, P.T.3
-
34
-
-
0028941627
-
Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs
-
Li GM, Modrich P. Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs. Proc Natl Acad Sci USA 1995; 92:1950-1954.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 1950-1954
-
-
Li, G.M.1
Modrich, P.2
-
35
-
-
0027933070
-
Mutations of two PMS homologues in hereditary nonpolyposis colon cancer
-
Nicolaides NC, Papadopoulos N, Liu B, et al. Mutations of two PMS homologues in hereditary nonpolyposis colon cancer. Nature 1994; 371:75-80.
-
(1994)
Nature
, vol.371
, pp. 75-80
-
-
Nicolaides, N.C.1
Papadopoulos, N.2
Liu, B.3
-
36
-
-
0028350601
-
Mutation of a mutL homolog in hereditary colon cancer
-
Papadopoulos N, Nicolaides NC, Wei YF, et al. Mutation of a mutL homolog in hereditary colon cancer. Science 1994; 263:1625-1629.
-
(1994)
Science
, vol.263
, pp. 1625-1629
-
-
Papadopoulos, N.1
Nicolaides, N.C.2
Wei, Y.F.3
-
37
-
-
0032532682
-
Human exonuclease I interacts with the mismatch repair protein hMSH2
-
Schmutte C, Marinescu RC, Sadoff MM, Guerrette S, Overhauser J, Fishel R Human exonuclease I interacts with the mismatch repair protein hMSH2. Cancer Res 1998; 58:4537-4542.
-
(1998)
Cancer Res
, vol.58
, pp. 4537-4542
-
-
Schmutte, C.1
Marinescu, R.C.2
Sadoff, M.M.3
Guerrette, S.4
Overhauser, J.5
Fishel, R.6
-
38
-
-
0032533518
-
Identification of a human gene encoding a homologue of Saccharomyces cerevisiae EXO1, an exonuclease implicated in mismatch repair and recombination
-
Tishkoff DX, Amin NS, Viars CS, Arden KC, Kolodner RD. Identification of a human gene encoding a homologue of Saccharomyces cerevisiae EXO1, an exonuclease implicated in mismatch repair and recombination. Cancer Res 1998; 58:5027-5031.
-
(1998)
Cancer Res
, vol.58
, pp. 5027-5031
-
-
Tishkoff, D.X.1
Amin, N.S.2
Viars, C.S.3
Arden, K.C.4
Kolodner, R.D.5
-
39
-
-
0030806219
-
Identification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2
-
Tishkoff DX, Boerger AL, Bertrand P, et al. Identification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2. Proc Natl Acad Sci USA 1997; 94:7487-7492.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 7487-7492
-
-
Tishkoff, D.X.1
Boerger, A.L.2
Bertrand, P.3
-
40
-
-
0031953114
-
The evolutionarily conserved zinc finger motif in the largest subunit of human replication protein A is required for DNA replication and mismatch repair but not for nucleotide excision repair
-
Lin YL, Shivji MK, Chen C, Kolodner R, Wood RD, Dutta A. The evolutionarily conserved zinc finger motif in the largest subunit of human replication protein A is required for DNA replication and mismatch repair but not for nucleotide excision repair. J Biol Chem 1998; 273:1453-1461.
-
(1998)
J Biol Chem
, vol.273
, pp. 1453-1461
-
-
Lin, Y.L.1
Shivji, M.K.2
Chen, C.3
Kolodner, R.4
Wood, R.D.5
Dutta, A.6
-
41
-
-
0032029995
-
ATP-dependent interaction of human mismatch repair proteins and dual role of PCNA in mismatch repair
-
Gu L, Hong Y, McCulloch S, Watanabe H, Li GM. ATP-dependent interaction of human mismatch repair proteins and dual role of PCNA in mismatch repair. Nucleic Acids Res 1998; 26:1173-1178.
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 1173-1178
-
-
Gu, L.1
Hong, Y.2
McCulloch, S.3
Watanabe, H.4
Li, G.M.5
-
42
-
-
0029905194
-
Evidence for involvement of yeast proliferating cell nuclear antigen in DNA mismatch repair
-
Johnson RE, Kovvali GK, Guzder SN, et al. Evidence for involvement of yeast proliferating cell nuclear antigen in DNA mismatch repair. J Biol Chem 1996; 271:27987-27990.
-
(1996)
J Biol Chem
, vol.271
, pp. 27987-27990
-
-
Johnson, R.E.1
Kovvali, G.K.2
Guzder, S.N.3
-
43
-
-
0030271999
-
Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis
-
Umar A, Buermeyer AB, Simon JA, et al. Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis. Cell 1996; 87:65-73.
-
(1996)
Cell
, vol.87
, pp. 65-73
-
-
Umar, A.1
Buermeyer, A.B.2
Simon, J.A.3
-
44
-
-
0030935386
-
DNA polymerase delta is required for human mismatch repair in vitro
-
Longley MJ, Pierce AJ, Modrich P. DNA polymerase delta is required for human mismatch repair in vitro. J Biol Chem 1997; 272:10917-10921.
-
(1997)
J Biol Chem
, vol.272
, pp. 10917-10921
-
-
Longley, M.J.1
Pierce, A.J.2
Modrich, P.3
-
45
-
-
24144447320
-
Reconstitution of 5′-directed human mismatch repair in a purified system
-
Zhang Y, Yuan F, Presnell SR, et al. Reconstitution of 5′-directed human mismatch repair in a purified system. Cell 2005; 122:693-705.
-
(2005)
Cell
, vol.122
, pp. 693-705
-
-
Zhang, Y.1
Yuan, F.2
Presnell, S.R.3
-
46
-
-
0028157956
-
Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene
-
Prolla TA, Christie DM, Liskay RM. Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene. Mol Cell Biol 1994; 14:407-415.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 407-415
-
-
Prolla, T.A.1
Christie, D.M.2
Liskay, R.M.3
-
47
-
-
0033986475
-
MLH3 : A DNA mismatch repair gene associated with mammalian microsatellite instability
-
Lipkin SM, Wang V, Jacoby R, et al. MLH3 : a DNA mismatch repair gene associated with mammalian microsatellite instability. Nat Genet 2000; 24:27-35.
-
(2000)
Nat Genet
, vol.24
, pp. 27-35
-
-
Lipkin, S.M.1
Wang, V.2
Jacoby, R.3
-
48
-
-
0035830953
-
MSH-MLH complexes formed at a DNA mismatch are disrupted by the PCNA sliding clamp
-
Bowers J, Tran PT, Joshi A, Liskay RM, Alani E. MSH-MLH complexes formed at a DNA mismatch are disrupted by the PCNA sliding clamp. J Mol Biol 2001; 306:957-968.
-
(2001)
J Mol Biol
, vol.306
, pp. 957-968
-
-
Bowers, J.1
Tran, P.T.2
Joshi, A.3
Liskay, R.M.4
Alani, E.5
-
49
-
-
0034711275
-
Functional interaction of proliferating cell nuclear antigen with MSH2-MSH6 and MSH2-MSH3 complexes
-
Clark AB, Valle F, Drotschmann K, Gary RK, Kunkel TA. Functional interaction of proliferating cell nuclear antigen with MSH2-MSH6 and MSH2-MSH3 complexes. J Biol Chem 2000; 275:36498-36501.
-
(2000)
J Biol Chem
, vol.275
, pp. 36498-36501
-
-
Clark, A.B.1
Valle, F.2
Drotschmann, K.3
Gary, R.K.4
Kunkel, T.A.5
-
50
-
-
0033764146
-
Proliferating cell nuclear antigen and Msh2p-Msh6p interact to form an active mispair recognition complex
-
Flores-Rozas H, Clark D, Kolodner RD. Proliferating cell nuclear antigen and Msh2p-Msh6p interact to form an active mispair recognition complex. Nat Genet 2000; 26:375-378.
-
(2000)
Nat Genet
, vol.26
, pp. 375-378
-
-
Flores-Rozas, H.1
Clark, D.2
Kolodner, R.D.3
-
51
-
-
0035868951
-
hMSH3 and hMSH6 interact with PCNA and colocalize with it to replication foci
-
Kleczkowska HE, Marra G, Lettieri T, Jiricny J. hMSH3 and hMSH6 interact with PCNA and colocalize with it to replication foci. Genes Dev 2001; 15:724-736.
-
(2001)
Genes Dev
, vol.15
, pp. 724-736
-
-
Kleczkowska, H.E.1
Marra, G.2
Lettieri, T.3
Jiricny, J.4
-
52
-
-
0033777562
-
The puzzle of PCNA's many partners
-
Warbrick E. The puzzle of PCNA's many partners. Bioessays 2000; 22:997-1006.
-
(2000)
Bioessays
, vol.22
, pp. 997-1006
-
-
Warbrick, E.1
-
53
-
-
0037414642
-
Transfer of the MSH2.MSH6 complex from proliferating cell nuclear antigen to mispaired bases in DNA
-
Lau PJ, Kolodner RD. Transfer of the MSH2.MSH6 complex from proliferating cell nuclear antigen to mispaired bases in DNA. J Biol Chem 2003; 278:14-17.
-
(2003)
J Biol Chem
, vol.278
, pp. 14-17
-
-
Lau, P.J.1
Kolodner, R.D.2
-
54
-
-
34248579736
-
The N terminus of Saccharomyces cerevisiae Msh6 is an unstructured tether to PCNA
-
Shell SS, Putnam CD, Kolodner RD. The N terminus of Saccharomyces cerevisiae Msh6 is an unstructured tether to PCNA. Mol Cell 2007; 26:565-578.
-
(2007)
Mol Cell
, vol.26
, pp. 565-578
-
-
Shell, S.S.1
Putnam, C.D.2
Kolodner, R.D.3
-
55
-
-
2342425404
-
Differential requirement for proliferating cell nuclear antigen in 50 and 30 nick-directed excision in human mismatch repair
-
Guo S, Presnell SR, Yuan F, Zhang Y, Gu L, Li GM. Differential requirement for proliferating cell nuclear antigen in 50 and 30 nick-directed excision in human mismatch repair. J Biol Chem 2004; 279:16912- 16917.
-
(2004)
J Biol Chem
, vol.279
, pp. 16912-16917
-
-
Guo, S.1
Presnell, S.R.2
Yuan, F.3
Zhang, Y.4
Gu, L.5
Li, G.M.6
-
56
-
-
0034958793
-
exol-Dependent mutator mutations: Model system for studying functional interactions in mismatch repair
-
Amin NS, Nguyen MN, Oh S, Kolodner RD. exol-Dependent mutator mutations: model system for studying functional interactions in mismatch repair. Mol Cell Biol 2001; 21:5142-5155.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 5142-5155
-
-
Amin, N.S.1
Nguyen, M.N.2
Oh, S.3
Kolodner, R.D.4
-
57
-
-
1442308349
-
Characterization of human exonuclease 1 in complex with mismatch repair proteins, subcellular localization and association with PCNA
-
Nielsen FC, Jager AC, Lutzen A, Bundgaard JR, Rasmussen LJ. Characterization of human exonuclease 1 in complex with mismatch repair proteins, subcellular localization and association with PCNA. Oncogene 2004; 23:1457-1468.
-
(2004)
Oncogene
, vol.23
, pp. 1457-1468
-
-
Nielsen, F.C.1
Jager, A.C.2
Lutzen, A.3
Bundgaard, J.R.4
Rasmussen, L.J.5
-
59
-
-
0345276522
-
Mechanism of 5′-directed excision in human mismatch repair
-
Genschel J, Modrich P. Mechanism of 5′-directed excision in human mismatch repair. Mol Cell 2003; 12:1077-1086.
-
(2003)
Mol Cell
, vol.12
, pp. 1077-1086
-
-
Genschel, J.1
Modrich, P.2
-
60
-
-
3042841883
-
A defined human system that supports bidirectional mismatch-provoked excision
-
Dzantiev L, Constantin N, Genschel J, Iyer RR, Burgers PM, Modrich P. A defined human system that supports bidirectional mismatch-provoked excision. Mol Cell 2004; 15:31-41.
-
(2004)
Mol Cell
, vol.15
, pp. 31-41
-
-
Dzantiev, L.1
Constantin, N.2
Genschel, J.3
Iyer, R.R.4
Burgers, P.M.5
Modrich, P.6
-
61
-
-
0037066720
-
Human exonuclease I is required for 5′ and 3′ mismatch repair
-
Genschel J, Bazemore LR, Modrich P. Human exonuclease I is required for 5′ and 3′ mismatch repair. J Biol Chem 2002; 277:13302-13311.
-
(2002)
J Biol Chem
, vol.277
, pp. 13302-13311
-
-
Genschel, J.1
Bazemore, L.R.2
Modrich, P.3
-
62
-
-
0037364995
-
Inactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility
-
Wei K, Clark AB, Wong E, et al. Inactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility. Genes Dev 2003; 17:603-614.
-
(2003)
Genes Dev
, vol.17
, pp. 603-614
-
-
Wei, K.1
Clark, A.B.2
Wong, E.3
-
63
-
-
33746855461
-
Regulation of replication protein A functions in mismatch repair by phosphorylation
-
Guo S, Zhang Y, Yuan F, et al. Regulation of replication protein A functions in mismatch repair by phosphorylation. J Biol Chem, 2006; 281:21607-21616.
-
(2006)
J Biol Chem
, vol.281
, pp. 21607-21616
-
-
Guo, S.1
Zhang, Y.2
Yuan, F.3
-
64
-
-
0032515156
-
The high mobility group domain protein Cmb1 of Schizosaccharomyces pombe binds to cytosines in base mismatches and opposite chemically altered guanines
-
Fleck O, Kunz C, Rudolph C, Kohli J. The high mobility group domain protein Cmb1 of Schizosaccharomyces pombe binds to cytosines in base mismatches and opposite chemically altered guanines. J Biol Chem 1998; 273:30398-30405.
-
(1998)
J Biol Chem
, vol.273
, pp. 30398-30405
-
-
Fleck, O.1
Kunz, C.2
Rudolph, C.3
Kohli, J.4
-
65
-
-
0017903484
-
Nonhistone proteins HMG1 and HMG2 change the DNA helical structure
-
Javaherian K, Liu JF, Wang JC. Nonhistone proteins HMG1 and HMG2 change the DNA helical structure. Science 1978; 199:1345-1346.
-
(1978)
Science
, vol.199
, pp. 1345-1346
-
-
Javaherian, K.1
Liu, J.F.2
Wang, J.C.3
-
66
-
-
0018787029
-
Nonhistone proteins HMG1 and HMG2 unwind DNA double helix
-
Javaherian K, Sadeghi M, Liu LF. Nonhistone proteins HMG1 and HMG2 unwind DNA double helix. Nucleic Acids Res 1979; 6:3569-3580.
-
(1979)
Nucleic Acids Res
, vol.6
, pp. 3569-3580
-
-
Javaherian, K.1
Sadeghi, M.2
Liu, L.F.3
-
67
-
-
2442705192
-
Evidence for involvement of HMGB1 protein in human DNAmismatch repair
-
Yuan F, Gu L, Guo S, Wang C, Li GM. Evidence for involvement of HMGB1 protein in human DNAmismatch repair. J Biol Chem 2004; 279:20935-20940.
-
(2004)
J Biol Chem
, vol.279
, pp. 20935-20940
-
-
Yuan, F.1
Gu, L.2
Guo, S.3
Wang, C.4
Li, G.M.5
-
68
-
-
2942627123
-
Signaling from DNA mispairs to mismatchrepair excision sites despite intervening blockades
-
Wang H, Hays JB. Signaling from DNA mispairs to mismatchrepair excision sites despite intervening blockades. Embo J 2004; 23:2126-2133.
-
(2004)
Embo J
, vol.23
, pp. 2126-2133
-
-
Wang, H.1
Hays, J.B.2
-
69
-
-
0030856429
-
MutS mediates heteroduplex loop formation by a translocation mechanism
-
Allen DJ, Makhov A, Grilley M, et al. MutS mediates heteroduplex loop formation by a translocation mechanism. Embo J 1997; 16:4467-4476.
-
(1997)
Embo J
, vol.16
, pp. 4467-4476
-
-
Allen, D.J.1
Makhov, A.2
Grilley, M.3
-
70
-
-
0032527704
-
Mismatch repair, molecular switches, and signal transduction
-
Fishel R. Mismatch repair, molecular switches, and signal transduction. Genes Dev 1998; 12:2096-2101.
-
(1998)
Genes Dev
, vol.12
, pp. 2096-2101
-
-
Fishel, R.1
-
71
-
-
0031456973
-
The human mismatch recognition complex hMSH2-hMSH6 functions as a novel molecular switch
-
Gradia S, Acharya S, Fishel R. The human mismatch recognition complex hMSH2-hMSH6 functions as a novel molecular switch. Cell 1997; 91:995-1005.
-
(1997)
Cell
, vol.91
, pp. 995-1005
-
-
Gradia, S.1
Acharya, S.2
Fishel, R.3
-
72
-
-
28444499354
-
Detection of high-affinity and sliding clamp modes for MSH2-MSH6 by single-molecule unzipping force analysis
-
Jiang J, Bai L, Surtees JA, Gemici Z, Wang MD, Alani E. Detection of high-affinity and sliding clamp modes for MSH2-MSH6 by single-molecule unzipping force analysis. Mol Cell 2005; 20:771-781.
-
(2005)
Mol Cell
, vol.20
, pp. 771-781
-
-
Jiang, J.1
Bai, L.2
Surtees, J.A.3
Gemici, Z.4
Wang, M.D.5
Alani, E.6
-
73
-
-
20444435104
-
Analysis of the interaction between the Saccharomyces cerevisiae MSH2-MSH6 and MLH1-PMS1 complexes with DNA using a reversible DNA end-blocking system
-
Mendillo ML, Mazur DJ, Kolodner RD. Analysis of the interaction between the Saccharomyces cerevisiae MSH2-MSH6 and MLH1-PMS1 complexes with DNA using a reversible DNA end-blocking system. J Biol Chem 2005; 280:22245-22257.
-
(2005)
J Biol Chem
, vol.280
, pp. 22245-22257
-
-
Mendillo, M.L.1
Mazur, D.J.2
Kolodner, R.D.3
-
74
-
-
34547882768
-
From the cover: Protein roadblocks and helix discontinuities are barriers to the initiation of mismatch repair
-
Pluciennik A, Modrich P. From the cover: protein roadblocks and helix discontinuities are barriers to the initiation of mismatch repair. Proc Natl Acad Sci USA 2007; 104:12709-12713.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 12709-12713
-
-
Pluciennik, A.1
Modrich, P.2
-
75
-
-
0026637946
-
Initiation of methyl-directed mismatch repair
-
Au KG, Welsh K, Modrich P. Initiation of methyl-directed mismatch repair. J Biol Chem 1992; 267:12142-12148.
-
(1992)
J Biol Chem
, vol.267
, pp. 12142-12148
-
-
Au, K.G.1
Welsh, K.2
Modrich, P.3
-
76
-
-
0027292234
-
An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair
-
Kat A, Thilly WG, Fang WH, Longley MJ, Li GM, Modrich P. An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair. Proc Natl Acad Sci USA 1993; 90:6424-6428.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 6424-6428
-
-
Kat, A.1
Thilly, W.G.2
Fang, W.H.3
Longley, M.J.4
Li, G.M.5
Modrich, P.6
-
77
-
-
0027936057
-
Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N′-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation
-
Koi M, Umar A, Chauhan DP, et al. Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N′-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation. Cancer Res 1994; 54:4308-4312.
-
(1994)
Cancer Res
, vol.54
, pp. 4308-4312
-
-
Koi, M.1
Umar, A.2
Chauhan, D.P.3
-
78
-
-
0031908505
-
The effect of different chemotherapeutic agents on the enrichment of DNA mismatch repair-deficient tumour cells
-
Fink D, Nebel S, Norris PS, et al. The effect of different chemotherapeutic agents on the enrichment of DNA mismatch repair-deficient tumour cells. Br J Cancer 1998; 77:703-708.
-
(1998)
Br J Cancer
, vol.77
, pp. 703-708
-
-
Fink, D.1
Nebel, S.2
Norris, P.S.3
-
79
-
-
0024328152
-
Isolation and characterization of cDNA clones derived from the divergently transcribed gene in the region upstream from the human dihydrofolate reductase gene
-
Fujii H, Shimada T. Isolation and characterization of cDNA clones derived from the divergently transcribed gene in the region upstream from the human dihydrofolate reductase gene. J Biol Chem 1989; 264:10057-10064.
-
(1989)
J Biol Chem
, vol.264
, pp. 10057-10064
-
-
Fujii, H.1
Shimada, T.2
-
80
-
-
0024385605
-
Dual bidirectional promoters at the mouse DHFR locus: Cloning and characterization of two mRNA classes of the divergently transcribed Rep-1 gene
-
Linton JP, Yen J-YJ, Selby E, et al. Dual bidirectional promoters at the mouse DHFR locus: cloning and characterization of two mRNA classes of the divergently transcribed Rep-1 gene. Mol Cell Biol 1989; 9:3058-3072.
-
(1989)
Mol Cell Biol
, vol.9
, pp. 3058-3072
-
-
Linton, J.P.1
Yen, J.-Y.J.2
Selby, E.3
-
81
-
-
0030885951
-
DHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSalpha/hMutSbeta ratio and reduces the efficiency of base-base mismatch repair
-
Drummond JT, Genschel J, Wolf E, Modrich P. DHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSalpha/hMutSbeta ratio and reduces the efficiency of base-base mismatch repair. Proc Natl Acad Sci USA 1997; 94:10144-10149.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 10144-10149
-
-
Drummond, J.T.1
Genschel, J.2
Wolf, E.3
Modrich, P.4
-
82
-
-
0032555141
-
Mismatch repair deficiency associated with overexpression of the MSH3 gene
-
Marra G, Iaccarino I, Lettieri T, Roscilli G, Delmastro P, Jiricny J. Mismatch repair deficiency associated with overexpression of the MSH3 gene. Proc Natl Acad Sci USA 1998; 95:8568-8573.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 8568-8573
-
-
Marra, G.1
Iaccarino, I.2
Lettieri, T.3
Roscilli, G.4
Delmastro, P.5
Jiricny, J.6
-
83
-
-
0037226473
-
The mismatch repair system is required for S-phase checkpoint activation
-
Brown KD, Rathi A, Kamath R, et al. The mismatch repair system is required for S-phase checkpoint activation. Nat Genet 2003; 33:80-84.
-
(2003)
Nat Genet
, vol.33
, pp. 80-84
-
-
Brown, K.D.1
Rathi, A.2
Kamath, R.3
-
84
-
-
0029665878
-
Human MutSalpha recognizes damaged DNA base pairs containing 06-methylguanine, 04-methylthymine, or the cisplatin-d(GpG) adduct
-
Duckett DR, Drummond JT, Murchie AI, et al. Human MutSalpha recognizes damaged DNA base pairs containing 06-methylguanine, 04-methylthymine, or the cisplatin-d(GpG) adduct. Proc Natl Acad Sci USA 1996; 93:6443-6447.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 6443-6447
-
-
Duckett, D.R.1
Drummond, J.T.2
Murchie, A.I.3
-
85
-
-
0033600234
-
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
-
Gong JG, Costanzo A, Yang HQ, et al. The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage. Nature 1999; 399:806-809.
-
(1999)
Nature
, vol.399
, pp. 806-809
-
-
Gong, J.G.1
Costanzo, A.2
Yang, H.Q.3
-
86
-
-
2442670292
-
Mismatch repair-dependent G2 checkpoint induced by low doses of SN1 type methylating agents requires the ATR kinase
-
Stojic L, Mojas N, Cejka P, et al. Mismatch repair-dependent G2 checkpoint induced by low doses of SN1 type methylating agents requires the ATR kinase. Genes Dev 2004; 18:1331-1344.
-
(2004)
Genes Dev
, vol.18
, pp. 1331-1344
-
-
Stojic, L.1
Mojas, N.2
Cejka, P.3
-
87
-
-
36148954290
-
MLH1 and ATM-dependent MAP kinase signaling is activated through C-Abl in response to the alkylator N-methyl-N′-nitro-N-nitrosoguanidine
-
Kim WJ, Rajasekaran B, Brown KD. MLH1 and ATM-dependent MAP kinase signaling is activated through C-Abl in response to the alkylator N-methyl-N′-nitro-N-nitrosoguanidine. J Biol Chem, 2007; 282:32021-32031.
-
(2007)
J Biol Chem
, vol.282
, pp. 32021-32031
-
-
Kim, W.J.1
Rajasekaran, B.2
Brown, K.D.3
-
88
-
-
0344284564
-
Interaction of mismatch repair protein PMS2 and the p5 3-related transcription factor p73 in apoptosis response to cisplatin
-
Shimodaira H, Yoshioka-Yamashita A, Kolodner RD, Wang JY. Interaction of mismatch repair protein PMS2 and the p5 3-related transcription factor p73 in apoptosis response to cisplatin. Proc Natl Acad Sci USA 2003; 100:2420-2425.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 2420-2425
-
-
Shimodaira, H.1
Yoshioka-Yamashita, A.2
Kolodner, R.D.3
Wang, J.Y.4
-
89
-
-
33646503204
-
ATR kinase activation mediated by MutSalpha and MutLalpha in response to cytotoxic 06-methylguanine adducts
-
Yoshioka K, Yoshioka Y, Hsieh P. ATR kinase activation mediated by MutSalpha and MutLalpha in response to cytotoxic 06-methylguanine adducts. Mol Cell 2006; 22:501-510.
-
(2006)
Mol Cell
, vol.22
, pp. 501-510
-
-
Yoshioka, K.1
Yoshioka, Y.2
Hsieh, P.3
-
90
-
-
34548259806
-
Exonuclease-1 deletion impairs DNA damage signaling and prolongs lifespan of telomere-dysfunctional mice
-
Schaetzlein S, Kodandaramireddy NR, Ju Z, et al. Exonuclease-1 deletion impairs DNA damage signaling and prolongs lifespan of telomere-dysfunctional mice. Cell 2007; 130:863-877.
-
(2007)
Cell
, vol.130
, pp. 863-877
-
-
Schaetzlein, S.1
Kodandaramireddy, N.R.2
Ju, Z.3
-
91
-
-
33747341054
-
Mismatch repair-dependent iterative excision at irreparable 06-methylguanine lesions in human nuclear extracts
-
York SJ, Modrich P. Mismatch repair-dependent iterative excision at irreparable 06-methylguanine lesions in human nuclear extracts. J Biol Chem 2006; 281:22674-22683.
-
(2006)
J Biol Chem
, vol.281
, pp. 22674-22683
-
-
York, S.J.1
Modrich, P.2
-
92
-
-
0037178722
-
Maintenance of genome stability in Saccharomyces cerevisiae
-
Kolodner RD, Putnam CD, Myung K. Maintenance of genome stability in Saccharomyces cerevisiae. Science 2002; 297:552-557.
-
(2002)
Science
, vol.297
, pp. 552-557
-
-
Kolodner, R.D.1
Putnam, C.D.2
Myung, K.3
-
93
-
-
4043181214
-
Cancer genes and the pathways they control
-
Vogelstein B, Kinzler KW. Cancer genes and the pathways they control. Nat Med 2004; 10:789-799.
-
(2004)
Nat Med
, vol.10
, pp. 789-799
-
-
Vogelstein, B.1
Kinzler, K.W.2
-
94
-
-
0034500024
-
DNA mismatch repair and genetic instability
-
Harfe BD, Jinks-Robertson S. DNA mismatch repair and genetic instability. Annu Rev Genet 2000; 34:359-399.
-
(2000)
Annu Rev Genet
, vol.34
, pp. 359-399
-
-
Harfe, B.D.1
Jinks-Robertson, S.2
-
95
-
-
0028204781
-
Mismatch repair proteins MutS and MutL inhibit RecA-catalyzed strand transfer between diverged DNAs
-
Worth L Jr, Clark S, Radman M, Modrich P. Mismatch repair proteins MutS and MutL inhibit RecA-catalyzed strand transfer between diverged DNAs. Proc Natl Acad Sci USA 1994; 91:3238-3241.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 3238-3241
-
-
Worth Jr, L.1
Clark, S.2
Radman, M.3
Modrich, P.4
-
96
-
-
15544388255
-
Distinct roles for the Saccharomyces cerevisiae mismatch repair proteins in heteroduplex rejection, mismatch repair and nonhomologous tail removal
-
Goldfarb T, Alani E. Distinct roles for the Saccharomyces cerevisiae mismatch repair proteins in heteroduplex rejection, mismatch repair and nonhomologous tail removal. Genetics 2005; 169:563-574.
-
(2005)
Genetics
, vol.169
, pp. 563-574
-
-
Goldfarb, T.1
Alani, E.2
-
97
-
-
3042546122
-
Heteroduplex rejection during single-strand annealing requires Sgs1 helicase and mismatch repair proteins Msh2 and Msh6 but not Pmsl
-
Sugawara N, Goldfarb T, Studamire B, Alani E, Haber JE. Heteroduplex rejection during single-strand annealing requires Sgs1 helicase and mismatch repair proteins Msh2 and Msh6 but not Pmsl. Proc Natl Acad Sci USA 2004; 101:9315-9320.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 9315-9320
-
-
Sugawara, N.1
Goldfarb, T.2
Studamire, B.3
Alani, E.4
Haber, J.E.5
-
98
-
-
0035158640
-
SGS1, the Saccharomyces cerevisiae homologue of BLM and WRN, suppresses genome instability and homeologous recombination
-
Myung K, Datta A, Chen C, Kolodner RD. SGS1, the Saccharomyces cerevisiae homologue of BLM and WRN, suppresses genome instability and homeologous recombination. Nat Genet 2001; 27:113-116.
-
(2001)
Nat Genet
, vol.27
, pp. 113-116
-
-
Myung, K.1
Datta, A.2
Chen, C.3
Kolodner, R.D.4
-
99
-
-
23044461827
-
RECQ1 helicase interacts with human mismatch repair factors that regulate genetic recombination
-
Doherty KM, Sharma S, Uzdilla L, et al. RECQ1 helicase interacts with human mismatch repair factors that regulate genetic recombination. J Biol Chem, 2005; 280:28085-28094.
-
(2005)
J Biol Chem
, vol.280
, pp. 28085-28094
-
-
Doherty, K.M.1
Sharma, S.2
Uzdilla, L.3
-
100
-
-
0141626769
-
The Bloomøs syndrome helicase interacts directly with the human DNA mismatch repair protein hMSH6
-
Pedrazzi G, Bachrati CZ, Selak N, et al. The Bloomøs syndrome helicase interacts directly with the human DNA mismatch repair protein hMSH6. Biol Chem 2003; 384:1155-1164.
-
(2003)
Biol Chem
, vol.384
, pp. 1155-1164
-
-
Pedrazzi, G.1
Bachrati, C.Z.2
Selak, N.3
-
101
-
-
34447318130
-
The FANCJ/MutLalpha interaction is required for correction of the cross-link response in FA-J cells
-
Peng M, Litman R, Xie J, Sharma S, Brosh RM Jr, Cantor SB. The FANCJ/MutLalpha interaction is required for correction of the cross-link response in FA-J cells. Embo J 2007; 26:3238-3249.
-
(2007)
Embo J
, vol.26
, pp. 3238-3249
-
-
Peng, M.1
Litman, R.2
Xie, J.3
Sharma, S.4
Brosh Jr, R.M.5
Cantor, S.B.6
-
102
-
-
35348946359
-
Double-strand breaks induce homologous recombinational repair of interstrand cross-links via cooperation of MSH2, ERCC1-XPF, REV3, and the Fanconi anemia pathway
-
Zhang N, Liu X, Li L, Legerski R. Double-strand breaks induce homologous recombinational repair of interstrand cross-links via cooperation of MSH2, ERCC1-XPF, REV3, and the Fanconi anemia pathway. DNA Repair (Amst) 2007; 6:1670-1678.
-
(2007)
DNA Repair (Amst)
, vol.6
, pp. 1670-1678
-
-
Zhang, N.1
Liu, X.2
Li, L.3
Legerski, R.4
-
103
-
-
0036005855
-
hMutSbeta is required for the recognition and uncoupling of psoralen interstrand cross-links in vitro
-
Zhang N, Lu X, Zhang X, Peterson CA, Legerski RJ. hMutSbeta is required for the recognition and uncoupling of psoralen interstrand cross-links in vitro. Mol Cell Biol 2002; 22:2388-2397.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 2388-2397
-
-
Zhang, N.1
Lu, X.2
Zhang, X.3
Peterson, C.A.4
Legerski, R.J.5
-
104
-
-
0036089964
-
Involvement of DNA mismatch repair in folate deficiency-induced apoptosis small star, filled
-
Gu L, Wu J, Qiu L, Jennings CD, Li GM. Involvement of DNA mismatch repair in folate deficiency-induced apoptosis small star, filled. J Nutr Biochem 2002; 13:355-363.
-
(2002)
J Nutr Biochem
, vol.13
, pp. 355-363
-
-
Gu, L.1
Wu, J.2
Qiu, L.3
Jennings, C.D.4
Li, G.M.5
-
105
-
-
14244250387
-
MSH2-MSH6 stimulates DNA polymerase eta, suggesting a role for A:T mutations in antibody genes
-
Wilson TM, Vaisman A, Martomo SA, et al. MSH2-MSH6 stimulates DNA polymerase eta, suggesting a role for A:T mutations in antibody genes. J Exp Med 2005; 201:637-645.
-
(2005)
J Exp Med
, vol.201
, pp. 637-645
-
-
Wilson, T.M.1
Vaisman, A.2
Martomo, S.A.3
-
106
-
-
33745498089
-
DNA repair in antibody somatic hypermutation
-
Casali P, Pal Z, Xu Z, Zan H. DNA repair in antibody somatic hypermutation. Trends Immunol 2006; 27:313-321.
-
(2006)
Trends Immunol
, vol.27
, pp. 313-321
-
-
Casali, P.1
Pal, Z.2
Xu, Z.3
Zan, H.4
-
107
-
-
36549008815
-
Activation-induced cytidine deaminase-dependent DNA breaks in class switch recombination occur during G1 phase of the cell cycle and depend upon mismatch repair
-
Schrader CE, Guikema JE, Linehan EK, Seising E, Stavnezer J. Activation-induced cytidine deaminase-dependent DNA breaks in class switch recombination occur during G1 phase of the cell cycle and depend upon mismatch repair. J Immunol 2007; 179:6064-6071.
-
(2007)
J Immunol
, vol.179
, pp. 6064-6071
-
-
Schrader, C.E.1
Guikema, J.E.2
Linehan, E.K.3
Seising, E.4
Stavnezer, J.5
-
108
-
-
1142299546
-
Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice
-
Bardwell PD, Woo CJ, Wei K, et al. Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice. Nat Immunol 2004; 5:224-229.
-
(2004)
Nat Immunol
, vol.5
, pp. 224-229
-
-
Bardwell, P.D.1
Woo, C.J.2
Wei, K.3
-
109
-
-
13144250122
-
Altered spectra of hypermutation in antibodies from mice deficient for the DNA mismatch repair protein PMS2
-
Winter DB, Phung QH, Umar A, et al. Altered spectra of hypermutation in antibodies from mice deficient for the DNA mismatch repair protein PMS2. Proc Natl Acad Sci USA 1998; 95:6953-6958.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6953-6958
-
-
Winter, D.B.1
Phung, Q.H.2
Umar, A.3
-
111
-
-
0029053371
-
Trinucleotide repeats that expand in human disease form hairpin structures in vitro
-
Gacy AM, Goellner G, Juranic N, Macura S, McMurray CT. Trinucleotide repeats that expand in human disease form hairpin structures in vitro. Cell 1995; 81:533-540.
-
(1995)
Cell
, vol.81
, pp. 533-540
-
-
Gacy, A.M.1
Goellner, G.2
Juranic, N.3
Macura, S.4
McMurray, C.T.5
-
112
-
-
0032708840
-
Msh2 deficiency prevents in vivo somatic instability of the CAG repeat in Huntington disease transgenic mice
-
Manley K, Shirley TL, Flaherty L, Messer A. Msh2 deficiency prevents in vivo somatic instability of the CAG repeat in Huntington disease transgenic mice. Nat Genet 1999; 23:471-473.
-
(1999)
Nat Genet
, vol.23
, pp. 471-473
-
-
Manley, K.1
Shirley, T.L.2
Flaherty, L.3
Messer, A.4
-
113
-
-
25844468819
-
(CAG)(n)-hairpin DNA binds to Msh2-Msh3 and changes properties of mismatch recognition
-
Owen BA, Yang Z, Lai M, et al. (CAG)(n)-hairpin DNA binds to Msh2-Msh3 and changes properties of mismatch recognition. Nat Struct Mol Biol 2005; 12:663-670.
-
(2005)
Nat Struct Mol Biol
, vol.12
, pp. 663-670
-
-
Owen, B.A.1
Yang, Z.2
Lai, M.3
-
114
-
-
0027158031
-
Clues to the pathogenesis of familial colorectal cancer
-
Aaltonen LA, Peltomaki P, Leach FS, et al. Clues to the pathogenesis of familial colorectal cancer. Science 1993; 260:812-816.
-
(1993)
Science
, vol.260
, pp. 812-816
-
-
Aaltonen, L.A.1
Peltomaki, P.2
Leach, F.S.3
-
115
-
-
0027285475
-
Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis
-
Ionov Y, Peinado MA, Malkhosyan S, Shibata D, Perucho M. Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature 1993; 363:558-561.
-
(1993)
Nature
, vol.363
, pp. 558-561
-
-
Ionov, Y.1
Peinado, M.A.2
Malkhosyan, S.3
Shibata, D.4
Perucho, M.5
-
116
-
-
0027314411
-
Microsatellite instability in cancer of the proximal colon
-
Thibodeau SN, Bren G, Schaid D. Microsatellite instability in cancer of the proximal colon. Science 1993; 260:816-819.
-
(1993)
Science
, vol.260
, pp. 816-819
-
-
Thibodeau, S.N.1
Bren, G.2
Schaid, D.3
-
117
-
-
0027306173
-
Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair
-
Strand M, Prolla TA, Liskay RM, Petes TD. Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair. Nature 1993; 365:274-276.
-
(1993)
Nature
, vol.365
, pp. 274-276
-
-
Strand, M.1
Prolla, T.A.2
Liskay, R.M.3
Petes, T.D.4
-
118
-
-
0027137935
-
Hypermutability and mismatch repair deficiency in RER+ tumor cells
-
Parsons R, Li GM, Longley MJ, et al. Hypermutability and mismatch repair deficiency in RER+ tumor cells. Cell 1993; 75:1227-1236.
-
(1993)
Cell
, vol.75
, pp. 1227-1236
-
-
Parsons, R.1
Li, G.M.2
Longley, M.J.3
-
119
-
-
0028301255
-
Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability
-
Umar A, Boyer JC, Thomas DC, et al. Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability. J Biol Chem 1994; 269:14367-14370.
-
(1994)
J Biol Chem
, vol.269
, pp. 14367-14370
-
-
Umar, A.1
Boyer, J.C.2
Thomas, D.C.3
-
120
-
-
0027485551
-
Genetic mapping of a second locus predisposing to hereditary non-polyposis colon cancer
-
Lindblom A, Tannergard P, Werelius B, Nordenskjold M. Genetic mapping of a second locus predisposing to hereditary non-polyposis colon cancer. Nat Genet 1993; 5:279-282.
-
(1993)
Nat Genet
, vol.5
, pp. 279-282
-
-
Lindblom, A.1
Tannergard, P.2
Werelius, B.3
Nordenskjold, M.4
-
121
-
-
0345357346
-
DNA mismatch repair and cancer
-
Li GM. DNA mismatch repair and cancer. Front Biosci 2003; 8:d997-d1017.
-
(2003)
Front Biosci
, vol.8
-
-
Li, G.M.1
-
123
-
-
0036828247
-
Functional alterations of human exonuclease 1 mutants identified in atypical hereditary nonpolyposis colorectal cancer syndrome
-
Sun X, Zheng L, Shen B. Functional alterations of human exonuclease 1 mutants identified in atypical hereditary nonpolyposis colorectal cancer syndrome. Cancer Res 2002; 62:6026-6030.
-
(2002)
Cancer Res
, vol.62
, pp. 6026-6030
-
-
Sun, X.1
Zheng, L.2
Shen, B.3
-
124
-
-
0032534069
-
-
Boland CR, Thibodeau SN, Hamilton SR, et al. A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 1998; 58:5248-5257.
-
Boland CR, Thibodeau SN, Hamilton SR, et al. A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 1998; 58:5248-5257.
-
-
-
-
125
-
-
0037158899
-
Mismatch repair deficiency in hematological malignancies with microsatellite instability
-
Gu L, Cline-Brown B, Zhang F, Qiu L, Li GM. Mismatch repair deficiency in hematological malignancies with microsatellite instability. Oncogene 2002; 21:5758-5764.
-
(2002)
Oncogene
, vol.21
, pp. 5758-5764
-
-
Gu, L.1
Cline-Brown, B.2
Zhang, F.3
Qiu, L.4
Li, G.M.5
-
126
-
-
0036639882
-
Deficiency of a novel mismatch repair activity in a bladder tumor cell line
-
Gu L, Wu J, Zhu BB, Li GM. Deficiency of a novel mismatch repair activity in a bladder tumor cell line. Nucleic Acids Res 2002; 30:2758-2763.
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 2758-2763
-
-
Gu, L.1
Wu, J.2
Zhu, B.B.3
Li, G.M.4
-
127
-
-
0031882250
-
Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repair
-
Prolla TA, Baker SM, Harris AC, et al. Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repair. Nat Genet 1998; 18:276-279.
-
(1998)
Nat Genet
, vol.18
, pp. 276-279
-
-
Prolla, T.A.1
Baker, S.M.2
Harris, A.C.3
-
128
-
-
0036303398
-
Mouse models for human DNA mismatch-repair gene defects
-
Wei K, Kucherlapati R, Edelmann W. Mouse models for human DNA mismatch-repair gene defects. Trends Mol Med 2002; 8:346-353.
-
(2002)
Trends Mol Med
, vol.8
, pp. 346-353
-
-
Wei, K.1
Kucherlapati, R.2
Edelmann, W.3
-
129
-
-
0029101616
-
Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer
-
de Wind N, Dekker M, Berns A, Radman M, te Riele H. Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer. Cell 1995; 82:321-330.
-
(1995)
Cell
, vol.82
, pp. 321-330
-
-
de Wind, N.1
Dekker, M.2
Berns, A.3
Radman, M.4
te Riele, H.5
-
130
-
-
0029111463
-
MSH2 deficient mice are viable and susceptible to lymphoid tumours
-
Reitmair AH, Schmits R, Ewel A, et al. MSH2 deficient mice are viable and susceptible to lymphoid tumours. Nat Genet 1995; 11:64-70.
-
(1995)
Nat Genet
, vol.11
, pp. 64-70
-
-
Reitmair, A.H.1
Schmits, R.2
Ewel, A.3
-
131
-
-
0030709433
-
Mutation in the mismatch repair gene Msh6 causes cancer susceptibility
-
Edelmann W, Yang K, Umar A, et al. Mutation in the mismatch repair gene Msh6 causes cancer susceptibility. Cell 1997; 91:467-477.
-
(1997)
Cell
, vol.91
, pp. 467-477
-
-
Edelmann, W.1
Yang, K.2
Umar, A.3
-
132
-
-
0032749569
-
Germ-line msh6 mutations in colorectal cancer families
-
Kolodner RD, Tytell JD, Schmeits JL, et al. Germ-line msh6 mutations in colorectal cancer families. Cancer Res 1999; 59:5068-5074.
-
(1999)
Cancer Res
, vol.59
, pp. 5068-5074
-
-
Kolodner, R.D.1
Tytell, J.D.2
Schmeits, J.L.3
-
133
-
-
0032726607
-
HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions
-
de Wind N, Dekker M, Claij N, et al. HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions. Nat Genet 1999; 23:359-362.
-
(1999)
Nat Genet
, vol.23
, pp. 359-362
-
-
de Wind, N.1
Dekker, M.2
Claij, N.3
-
134
-
-
0034652474
-
The DNA mismatch repair genes Msh3 and Msh6 cooperate in intestinal tumor suppression
-
Edelmann W, Umar A, Yang K, et al. The DNA mismatch repair genes Msh3 and Msh6 cooperate in intestinal tumor suppression. Cancer Res 2000; 60:803-807.
-
(2000)
Cancer Res
, vol.60
, pp. 803-807
-
-
Edelmann, W.1
Umar, A.2
Yang, K.3
-
135
-
-
8944232867
-
Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over
-
Baker SM, Plug AW, Prolla TA, et al. Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over. Nat Genet 1996; 13:336-342.
-
(1996)
Nat Genet
, vol.13
, pp. 336-342
-
-
Baker, S.M.1
Plug, A.W.2
Prolla, T.A.3
-
136
-
-
15844367099
-
Meiotic pachytene arrest in MLH1-deficientmice
-
Edelmann W, Cohen PE, Kane M, et al. Meiotic pachytene arrest in MLH1-deficientmice. Cell 1996; 85:1125-1134.
-
(1996)
Cell
, vol.85
, pp. 1125-1134
-
-
Edelmann, W.1
Cohen, P.E.2
Kane, M.3
-
137
-
-
0036699091
-
Meiotic arrest and aneuploidy in MLH3-deficient mice
-
Lipkin SM, Moens PB, Wang V, et al. Meiotic arrest and aneuploidy in MLH3-deficient mice. Nat Genet 2002; 31:385-390.
-
(2002)
Nat Genet
, vol.31
, pp. 385-390
-
-
Lipkin, S.M.1
Moens, P.B.2
Wang, V.3
-
138
-
-
0029099989
-
Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis
-
Baker SM, Bronner CE, Zhang L, et al. Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis. Cell 1995; 82:309-319.
-
(1995)
Cell
, vol.82
, pp. 309-319
-
-
Baker, S.M.1
Bronner, C.E.2
Zhang, L.3
-
139
-
-
0031017268
-
Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines
-
Kane MF, Loda M, Gaida GM, et al. Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines. Cancer Res 1997; 57:808-811.
-
(1997)
Cancer Res
, vol.57
, pp. 808-811
-
-
Kane, M.F.1
Loda, M.2
Gaida, G.M.3
-
141
-
-
0032522658
-
Microsatellite instability in colorectal cancer: Different mutator phenotypes and the principal involvement of hMLH1
-
Thibodeau SN, French AJ, Cunningham JM, et al. Microsatellite instability in colorectal cancer: different mutator phenotypes and the principal involvement of hMLH1. Cancer Res 1998; 58:1713-1718.
-
(1998)
Cancer Res
, vol.58
, pp. 1713-1718
-
-
Thibodeau, S.N.1
French, A.J.2
Cunningham, J.M.3
-
142
-
-
0037099602
-
A hereditary nonpolyposis colorectal carcinoma case associated with hypermethylation of the MLH1 gene in normal tissue and loss of heterozygosity of the unmethylated allele in the resulting microsatellite instability-high tumor
-
Gazzoli I, Loda M, Garber J, Syngal S, Kolodner RD. A hereditary nonpolyposis colorectal carcinoma case associated with hypermethylation of the MLH1 gene in normal tissue and loss of heterozygosity of the unmethylated allele in the resulting microsatellite instability-high tumor. Cancer Res 2002; 62:3925-3928.
-
(2002)
Cancer Res
, vol.62
, pp. 3925-3928
-
-
Gazzoli, I.1
Loda, M.2
Garber, J.3
Syngal, S.4
Kolodner, R.D.5
-
143
-
-
33749122904
-
Heritable germline epimutation of MSH2 in a family with hereditary nonpolyposis colorectal cancer
-
Chan TL, Yuen ST, Kong CK, et al. Heritable germline epimutation of MSH2 in a family with hereditary nonpolyposis colorectal cancer. Nat Genet 2006; 38:1178-1183.
-
(2006)
Nat Genet
, vol.38
, pp. 1178-1183
-
-
Chan, T.L.1
Yuen, S.T.2
Kong, C.K.3
-
144
-
-
33846973361
-
Inheritance of a cancerassociated MLH1 germ-line epimutation
-
Hitchins MP, Wong JJ, Suthers G, et al. Inheritance of a cancerassociated MLH1 germ-line epimutation. N Engl J Med 2001; 356:697-705.
-
(2001)
N Engl J Med
, vol.356
, pp. 697-705
-
-
Hitchins, M.P.1
Wong, J.J.2
Suthers, G.3
-
145
-
-
2442424419
-
Germline epimutation of MLH1 in individuals with multiple cancers
-
Suter CM, Martin DI, Ward RL. Germline epimutation of MLH1 in individuals with multiple cancers. Nat Genet 2004; 36:497-501.
-
(2004)
Nat Genet
, vol.36
, pp. 497-501
-
-
Suter, C.M.1
Martin, D.I.2
Ward, R.L.3
-
146
-
-
13144307115
-
Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers
-
Veigl ML, Kasturi L, Olechnowicz J, et al. Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers. Proc Natl Acad Sci USA 1998; 95:8698-8702.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 8698-8702
-
-
Veigl, M.L.1
Kasturi, L.2
Olechnowicz, J.3
-
147
-
-
13144266670
-
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma
-
Herman JG, Umar A, Polyak K, et al. Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma. Proc Natl Acad Sci USA 1998; 95:6870-6875.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6870-6875
-
-
Herman, J.G.1
Umar, A.2
Polyak, K.3
-
148
-
-
0030932869
-
Cancer-susceptibility genes. Gatekeepers and caretakers
-
Kinzler KW, Vogelstein B. Cancer-susceptibility genes. Gatekeepers and caretakers. Nature 1997; 386:761, 763.
-
(1997)
Nature
, vol.386
, Issue.761
, pp. 763
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
149
-
-
0029066689
-
Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability
-
Markowitz S, Wang J, Myeroff L, et al. Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability. Science 1995; 268:1336-1338.
-
(1995)
Science
, vol.268
, pp. 1336-1338
-
-
Markowitz, S.1
Wang, J.2
Myeroff, L.3
-
150
-
-
0036569940
-
Mutations at coding repeat sequences in mismatch repair-deficient human cancers: Toward a new concept of target genes for instability
-
Duval A, Hamelin R. Mutations at coding repeat sequences in mismatch repair-deficient human cancers: toward a new concept of target genes for instability. Cancer Res 2002; 62:2447-2454.
-
(2002)
Cancer Res
, vol.62
, pp. 2447-2454
-
-
Duval, A.1
Hamelin, R.2
|