-
1
-
-
2342565902
-
A means to a DNA end: The many roles of Ku
-
Downs JA, Jackson SP. A means to a DNA end: the many roles of Ku. Nat Rev Mol Cell Biol 2004; 5: 367–378.
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, pp. 367-378
-
-
Downs, J.A.1
Jackson, S.P.2
-
2
-
-
0030858967
-
Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination
-
Gu Y, Jin S, Gao Y, Weaver DT, Alt FW. Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination. Proc Natl Acad Sci USA 1997; 94: 8076–8081.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 8076-8081
-
-
Gu, Y.1
Jin, S.2
Gao, Y.3
Weaver, D.T.4
Alt, F.W.5
-
3
-
-
0031433517
-
Growth retardation and leaky SCID phenotype of Ku70-deficient mice
-
Gu Y, Seidl KJ, Rathbun GA, Zhu C, Manis JP, van der Stoep N et al. Growth retardation and leaky SCID phenotype of Ku70-deficient mice. Immunity 1997; 7: 653–665.
-
(1997)
Immunity
, vol.7
, pp. 653-665
-
-
Gu, Y.1
Seidl, K.J.2
Rathbun, G.A.3
Zhu, C.4
Manis, J.P.5
van der Stoep, N.6
-
4
-
-
0032113987
-
Ku70: A candidate tumor suppressor gene for murine T cell lymphoma
-
Li GC, Ouyang H, Li X, Nagasawa H, Little JB, Chen DJ et al. Ku70: a candidate tumor suppressor gene for murine T cell lymphoma. Mol Cell 1998; 2: 1–8.
-
(1998)
Mol Cell
, vol.2
, pp. 1-8
-
-
Li, G.C.1
Ouyang, H.2
Li, X.3
Nagasawa, H.4
Little, J.B.5
Chen, D.J.6
-
5
-
-
0032526290
-
Ku70 is required for late B cell development and immunoglobulin heavy chain class switching
-
Manis JP, Gu Y, Lansford R, Sonoda E, Ferrini R, Davidson L et al. Ku70 is required for late B cell development and immunoglobulin heavy chain class switching. J Exp Med 1998; 187: 2081–2089.
-
(1998)
J Exp Med
, vol.187
, pp. 2081-2089
-
-
Manis, J.P.1
Gu, Y.2
Lansford, R.3
Sonoda, E.4
Ferrini, R.5
Davidson, L.6
-
6
-
-
36849088515
-
Deletion of Ku70, Ku80, or both causes early aging without substantially increased cancer
-
Li H, Vogel H, Holcomb VB, Gu Y, Hasty P. Deletion of Ku70, Ku80, or both causes early aging without substantially increased cancer. Mol Cell Biol 2007; 27: 8205–8214.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 8205-8214
-
-
Li, H.1
Vogel, H.2
Holcomb, V.B.3
Gu, Y.4
Hasty, P.5
-
7
-
-
0034646304
-
Defective embryonic neurogenesis in Ku-deficient but not DNA-dependent protein kinase catalytic subunit-deficient mice
-
Gu Y, Sekiguchi J, Gao Y, Dikkes P, Frank K, Ferguson D et al. Defective embryonic neurogenesis in Ku-deficient but not DNA-dependent protein kinase catalytic subunit-deficient mice. Proc Natl Acad Sci USA 2000; 97: 2668–2673.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 2668-2673
-
-
Gu, Y.1
Sekiguchi, J.2
Gao, Y.3
Dikkes, P.4
Frank, K.5
Ferguson, D.6
-
8
-
-
34548191070
-
Bax-inhibiting peptides derived from Ku70 and cell-penetrating pentapeptides
-
Gomez JA, Gama V, Yoshida T, Sun W, Hayes P, Leskov K et al. Bax-inhibiting peptides derived from Ku70 and cell-penetrating pentapeptides. Biochem Soc Trans 2007; 35(Pt 4): 797–801.
-
(2007)
Biochem Soc Trans
, vol.35
, Issue.4
, pp. 797-801
-
-
Gomez, J.A.1
Gama, V.2
Yoshida, T.3
Sun, W.4
Hayes, P.5
Leskov, K.6
-
9
-
-
0033179760
-
BCL-2 family members and the mitochondria in apoptosis
-
Gross A, McDonnell JM, Korsmeyer SJ. BCL-2 family members and the mitochondria in apoptosis. Genes Dev 1999; 13: 1899–1911.
-
(1999)
Genes Dev
, vol.13
, pp. 1899-1911
-
-
Gross, A.1
McDonnell, J.M.2
Korsmeyer, S.J.3
-
10
-
-
0035957653
-
Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
-
Wei MC, Zong WX, Cheng EH, Lindsten T, Panoutsakopoulou V, Ross AJ et al. Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science 2001; 292: 727–730.
-
(2001)
Science
, vol.292
, pp. 727-730
-
-
Wei, M.C.1
Zong, W.X.2
Cheng, E.H.3
Lindsten, T.4
Panoutsakopoulou, V.5
Ross, A.J.6
-
11
-
-
0345329610
-
Ku autoantigen affects the susceptibility to anticancer drugs
-
Kim SH, Kim D, Han JS, Jeong CS, Chung BS, Kang CD et al. Ku autoantigen affects the susceptibility to anticancer drugs. Cancer Res 1999; 59: 4012–4017.
-
(1999)
Cancer Res
, vol.59
, pp. 4012-4017
-
-
Kim, S.H.1
Kim, D.2
Han, J.S.3
Jeong, C.S.4
Chung, B.S.5
Kang, C.D.6
-
12
-
-
67349258111
-
Hdm2 is a ubiquitin ligase of Ku70-Akt promotes cell survival by inhibiting Hdm2-dependent Ku70 destabilization
-
Gama V, Gomez JA, Mayo LD, Jackson MW, Danielpour D, Song K et al. Hdm2 is a ubiquitin ligase of Ku70-Akt promotes cell survival by inhibiting Hdm2-dependent Ku70 destabilization. Cell Death Differ 2009; 16: 758–769.
-
(2009)
Cell Death Differ
, vol.16
, pp. 758-769
-
-
Gama, V.1
Gomez, J.A.2
Mayo, L.D.3
Jackson, M.W.4
Danielpour, D.5
Song, K.6
-
13
-
-
12144286529
-
Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis
-
Cohen HY, Lavu S, Bitterman KJ, Hekking B, Imahiyerobo TA, Miller C et al. Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis. Mol Cell 2004; 13: 627–638.
-
(2004)
Mol Cell
, vol.13
, pp. 627-638
-
-
Cohen, H.Y.1
Lavu, S.2
Bitterman, K.J.3
Hekking, B.4
Imahiyerobo, T.A.5
Miller, C.6
-
14
-
-
3142740860
-
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
-
Cohen HY, Miller C, Bitterman KJ, Wall NR, Hekking B, Kessler B et al. Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science 2004; 305: 390–392.
-
(2004)
Science
, vol.305
, pp. 390-392
-
-
Cohen, H.Y.1
Miller, C.2
Bitterman, K.J.3
Wall, N.R.4
Hekking, B.5
Kessler, B.6
-
15
-
-
16344376556
-
Ku70 acetylation mediates neuroblastoma cell death induced by histone deacetylase inhibitors
-
Subramanian C, Opipari AW Jr., Bian X, Castle VP, Kwok RP. Ku70 acetylation mediates neuroblastoma cell death induced by histone deacetylase inhibitors. Proc Natl Acad Sci USA 2005; 102: 4842–4847.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 4842-4847
-
-
Subramanian, C.1
Opipari, A.W.2
Bian, X.3
Castle, V.P.4
Kwok, R.P.5
-
16
-
-
36249024811
-
Bax-inhibiting peptide protects cells from polyglutamine toxicity caused by Ku70 acetylation
-
Li Y, Yokota T, Gama V, Yoshida T, Gomez JA, Ishikawa K et al. Bax-inhibiting peptide protects cells from polyglutamine toxicity caused by Ku70 acetylation. Cell Death Differ 2007; 14: 2058–2067.
-
(2007)
Cell Death Differ
, vol.14
, pp. 2058-2067
-
-
Li, Y.1
Yokota, T.2
Gama, V.3
Yoshida, T.4
Gomez, J.A.5
Ishikawa, K.6
-
17
-
-
34247564493
-
Interaction of a cyclin E fragment with ku70 regulates bax-mediated apoptosis
-
Mazumder S, Plesca D, Kinter M, Almasan A. Interaction of a cyclin E fragment with ku70 regulates bax-mediated apoptosis. Mol Cell Biol 2007; 27: 3511–3520.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 3511-3520
-
-
Mazumder, S.1
Plesca, D.2
Kinter, M.3
Almasan, A.4
-
18
-
-
57649143245
-
A C-terminal fragment of cyclin E, generated by caspase-mediated cleavage, is degraded in the absence of a recognizable phosphodegron
-
Plesca D, Mazumder S, Gama V, Matsuyama S, Almasan A. A C-terminal fragment of cyclin E, generated by caspase-mediated cleavage, is degraded in the absence of a recognizable phosphodegron. J Biol Chem 2008; 283: 30796–30803.
-
(2008)
J Biol Chem
, vol.283
, pp. 30796-30803
-
-
Plesca, D.1
Mazumder, S.2
Gama, V.3
Matsuyama, S.4
Almasan, A.5
-
19
-
-
52049125708
-
NBS1 regulates a novel apoptotic pathway through Bax activation
-
Iijima K, Muranaka C, Kobayashi J, Sakamoto S, Komatsu K, Matsuura S et al. NBS1 regulates a novel apoptotic pathway through Bax activation. DNA Repair (Amst) 2008; 7: 1705–1716.
-
(2008)
DNA Repair (Amst)
, vol.7
, pp. 1705-1716
-
-
Iijima, K.1
Muranaka, C.2
Kobayashi, J.3
Sakamoto, S.4
Komatsu, K.5
Matsuura, S.6
-
20
-
-
77951845217
-
Resveratrol prevents antibody-induced apoptotic death of retinal cells through upregulation of Sirt1 and Ku70
-
Anekonda TS, Adamus G. Resveratrol prevents antibody-induced apoptotic death of retinal cells through upregulation of Sirt1 and Ku70. BMC Res Notes 2008; 1: 122.
-
(2008)
BMC Res Notes
, vol.1
, pp. 122
-
-
Anekonda, T.S.1
Adamus, G.2
-
21
-
-
59449110489
-
Interleukin-6 affects cell death escaping mechanisms acting on Bax-Ku70-Clusterin interactions in human colon cancer progression
-
Pucci S, Mazzarelli P, Sesti F, Boothman DA, Spagnoli LG. Interleukin-6 affects cell death escaping mechanisms acting on Bax-Ku70-Clusterin interactions in human colon cancer progression. Cell Cycle 2009; 8: 473–481.
-
(2009)
Cell Cycle
, vol.8
, pp. 473-481
-
-
Pucci, S.1
Mazzarelli, P.2
Sesti, F.3
Boothman, D.A.4
Spagnoli, L.G.5
-
22
-
-
53549105529
-
SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70
-
Sundaresan NR, Samant SA, Pillai VB, Rajamohan SB, Gupta MP. SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70. Mol Cell Biol 2008; 28: 6384–6401.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 6384-6401
-
-
Sundaresan, N.R.1
Samant, S.A.2
Pillai, V.B.3
Rajamohan, S.B.4
Gupta, M.P.5
-
23
-
-
58849123363
-
Intracellular clusterin inhibits mitochondrial apoptosis by suppressing p53-activating stress signals and stabilizing the cytosolic Ku70-Bax protein complex
-
Trougakos IP, Lourda M, Antonelou MH, Kletsas D, Gorgoulis VG, Papassideri IS et al. Intracellular clusterin inhibits mitochondrial apoptosis by suppressing p53-activating stress signals and stabilizing the cytosolic Ku70-Bax protein complex. Clin Cancer Res 2009; 15: 48–59.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 48-59
-
-
Trougakos, I.P.1
Lourda, M.2
Antonelou, M.H.3
Kletsas, D.4
Gorgoulis, V.G.5
Papassideri, I.S.6
-
24
-
-
66449099052
-
P53 acetylation is crucial for its transcription-independent proapoptotic functions
-
Yamaguchi H, Woods NT, Piluso LG, Lee HH, Chen J, Bhalla KN et al. p53 acetylation is crucial for its transcription-independent proapoptotic functions. J Biol Chem 2009; 284: 11171–11183.
-
(2009)
J Biol Chem
, vol.284
, pp. 11171-11183
-
-
Yamaguchi, H.1
Woods, N.T.2
Piluso, L.G.3
Lee, H.H.4
Chen, J.5
Bhalla, K.N.6
-
25
-
-
70449419707
-
Ku70 regulates Bax-mediated pathogenesis in laminin-alpha2-deficient human muscle cells and mouse models of congenital muscular dystrophy
-
Vishnudas VK, Miller JB. Ku70 regulates Bax-mediated pathogenesis in laminin-alpha2-deficient human muscle cells and mouse models of congenital muscular dystrophy. Hum Mol Genet 2009; 18: 4467–4477.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 4467-4477
-
-
Vishnudas, V.K.1
Miller, J.B.2
-
26
-
-
84862639339
-
Interaction of caveolin-1 with Ku70 inhibits Bax-mediated apoptosis
-
Zou H, Volonte D, Galbiati F. Interaction of caveolin-1 with Ku70 inhibits Bax-mediated apoptosis. PLoS One 2012; 7: e39379.
-
(2012)
Plos One
, vol.7
-
-
Zou, H.1
Volonte, D.2
Galbiati, F.3
-
27
-
-
84861989101
-
Human embryonic stem cells have constitutively active Bax at the Golgi and are primed to undergo rapid apoptosis
-
Dumitru R, Gama V, Fagan BM, Bower JJ, Swahari V, Pevny LH et al. Human embryonic stem cells have constitutively active Bax at the Golgi and are primed to undergo rapid apoptosis. Mol Cell 2012; 46: 573–583.
-
(2012)
Mol Cell
, vol.46
, pp. 573-583
-
-
Dumitru, R.1
Gama, V.2
Fagan, B.M.3
Bower, J.J.4
Swahari, V.5
Pevny, L.H.6
-
28
-
-
84869020640
-
Role of Ku70 and Bax in epigallocatechin-3-gallate-induced apoptosis of A549 cells in vivo
-
Li JJ, Gu QH, Li M, Yang HP, Cao LM, Hu CP. Role of Ku70 and Bax in epigallocatechin-3-gallate-induced apoptosis of A549 cells in vivo. Oncol Lett 2013; 5: 101–106.
-
(2013)
Oncol Lett
, vol.5
, pp. 101-106
-
-
Li, J.J.1
Gu, Q.H.2
Li, M.3
Yang, H.P.4
Cao, L.M.5
Hu, C.P.6
-
29
-
-
84902242508
-
Role of Ku70 in deubiquitination of Mcl-1 and suppression of apoptosis
-
Wang B, Xie M, Li R, Owonikoko TK, Ramalingam SS, Khuri FR et al. Role of Ku70 in deubiquitination of Mcl-1 and suppression of apoptosis. Cell Death Differ 2014; 21: 1160–1169.
-
(2014)
Cell Death Differ
, vol.21
, pp. 1160-1169
-
-
Wang, B.1
Xie, M.2
Li, R.3
Owonikoko, T.K.4
Ramalingam, S.S.5
Khuri, F.R.6
-
30
-
-
79951673772
-
The DNA repair complex Ku70/86 modulates Apaf1 expression upon DNA damage
-
De Zio D, Bordi M, Tino E, Lanzuolo C, Ferraro E, Mora E et al. The DNA repair complex Ku70/86 modulates Apaf1 expression upon DNA damage. Cell Death Differ 2011; 18: 516–527.
-
(2011)
Cell Death Differ
, vol.18
, pp. 516-527
-
-
de Zio, D.1
Bordi, M.2
Tino, E.3
Lanzuolo, C.4
Ferraro, E.5
Mora, E.6
-
31
-
-
77954444618
-
Macrophage migration inhibitory factor-knockout mice are long lived and respond to caloric restriction
-
Harper JM, Wilkinson JE, Miller RA. Macrophage migration inhibitory factor-knockout mice are long lived and respond to caloric restriction. FASEB J 2010; 24: 2436–2442.
-
(2010)
FASEB J
, vol.24
, pp. 2436-2442
-
-
Harper, J.M.1
Wilkinson, J.E.2
Miller, R.A.3
-
32
-
-
0032520195
-
Widespread elimination of naturally occurring neuronal death in Bax-deficient mice
-
White FA, Keller-Peck CR, Knudson CM, Korsmeyer SJ, Snider WD. Widespread elimination of naturally occurring neuronal death in Bax-deficient mice. J Neurosci 1998; 18: 1428–1439.
-
(1998)
J Neurosci
, vol.18
, pp. 1428-1439
-
-
White, F.A.1
Keller-Peck, C.R.2
Knudson, C.M.3
Korsmeyer, S.J.4
Snider, W.D.5
-
33
-
-
29144533365
-
Involvement of the ubiquitin pathway in decreasing Ku70 levels in response to drug-induced apoptosis
-
Gama V, Yoshida T, Gomez JA, Basile DP, Mayo LD, Haas AL et al. Involvement of the ubiquitin pathway in decreasing Ku70 levels in response to drug-induced apoptosis. Exp Cell Res 2006; 312: 488–499.
-
(2006)
Exp Cell Res
, vol.312
, pp. 488-499
-
-
Gama, V.1
Yoshida, T.2
Gomez, J.A.3
Basile, D.P.4
Mayo, L.D.5
Haas, A.L.6
-
34
-
-
84872244996
-
Comparison of velocity vector imaging echocardiography with magnetic resonance imaging in mouse models of cardiomyopathy
-
Azam S, Desjardins CL, Schluchter M, Liner A, Stelzer JE, Yu X et al. Comparison of velocity vector imaging echocardiography with magnetic resonance imaging in mouse models of cardiomyopathy. Circ Cardiovasc Imaging 2012; 5: 776–781.
-
(2012)
Circ Cardiovasc Imaging
, vol.5
, pp. 776-781
-
-
Azam, S.1
Desjardins, C.L.2
Schluchter, M.3
Liner, A.4
Stelzer, J.E.5
Yu, X.6
-
35
-
-
0032827888
-
Deletion of Ku86 causes early onset of senescence in mice
-
Vogel H, Lim DS, Karsenty G, Finegold M, Hasty P. Deletion of Ku86 causes early onset of senescence in mice. Proc Natl Acad Sci USA 1999; 96: 10770–10775.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 10770-10775
-
-
Vogel, H.1
Lim, D.S.2
Karsenty, G.3
Finegold, M.4
Hasty, P.5
-
36
-
-
2342458205
-
Aging and nuclear organization: Lamins and progeria
-
Mounkes LC, Stewart CL. Aging and nuclear organization: lamins and progeria. Curr Opin Cell Biol 2004; 16: 322–327.
-
(2004)
Curr Opin Cell Biol
, vol.16
, pp. 322-327
-
-
Mounkes, L.C.1
Stewart, C.L.2
-
37
-
-
0037673940
-
A progeroid syndrome in mice is caused by defects in A-type lamins
-
Mounkes LC, Kozlov S, Hernandez L, Sullivan T, Stewart CL. A progeroid syndrome in mice is caused by defects in A-type lamins. Nature 2003; 423: 298–301.
-
(2003)
Nature
, vol.423
, pp. 298-301
-
-
Mounkes, L.C.1
Kozlov, S.2
Hernandez, L.3
Sullivan, T.4
Stewart, C.L.5
-
38
-
-
0027942484
-
Emphysema: Definition, imaging, and quantification
-
Thurlbeck WM, Muller NL. Emphysema: definition, imaging, and quantification. AJR Am J Roentgenol 1994; 163: 1017–1025.
-
(1994)
AJR am J Roentgenol
, vol.163
, pp. 1017-1025
-
-
Thurlbeck, W.M.1
Muller, N.L.2
-
39
-
-
0035094309
-
Pathogenesis and pathology of COPD
-
Turato G, Zuin R, Saetta M. Pathogenesis and pathology of COPD. Respiration 2001; 68: 117–128.
-
(2001)
Respiration
, vol.68
, pp. 117-128
-
-
Turato, G.1
Zuin, R.2
Saetta, M.3
-
40
-
-
84877108832
-
The defect of Ku70 affects sensitivity to X-ray and radiation-induced caspase-dependent apoptosis in lung cells
-
Koike M, Yutoku Y, Koike A. The defect of Ku70 affects sensitivity to X-ray and radiation-induced caspase-dependent apoptosis in lung cells. J Vet Med Sci 2012; 75: 415–420.
-
(2012)
J Vet Med Sci
, vol.75
, pp. 415-420
-
-
Koike, M.1
Yutoku, Y.2
Koike, A.3
-
41
-
-
80052619178
-
Accumulation of Ku70 at DNA double-strand breaks in living epithelial cells
-
Koike M, Yutoku Y, Koike A. Accumulation of Ku70 at DNA double-strand breaks in living epithelial cells. Exp Cell Res 2011; 317: 2429–2437.
-
(2011)
Exp Cell Res
, vol.317
, pp. 2429-2437
-
-
Koike, M.1
Yutoku, Y.2
Koike, A.3
-
42
-
-
84873673503
-
New models of pulmonary hypertension based on VEGF receptor blockade-induced endothelial cell apoptosis
-
Nicolls MR, Mizuno S, Taraseviciene-Stewart L, Farkas L, Drake JI, Al Husseini A et al. New models of pulmonary hypertension based on VEGF receptor blockade-induced endothelial cell apoptosis. Pulm Circ 2012; 2: 434–442.
-
(2012)
Pulm Circ
, vol.2
, pp. 434-442
-
-
Nicolls, M.R.1
Mizuno, S.2
Taraseviciene-Stewart, L.3
Farkas, L.4
Drake, J.I.5
Al Husseini, A.6
-
43
-
-
84871211326
-
Pathobiology of pulmonary arterial hypertension and right ventricular failure
-
Voelkel NF, Gomez-Arroyo J, Abbate A, Bogaard HJ, Nicolls MR. Pathobiology of pulmonary arterial hypertension and right ventricular failure. Eur Respir J 2012; 40: 1555–1565.
-
(2012)
Eur Respir J
, vol.40
, pp. 1555-1565
-
-
Voelkel, N.F.1
Gomez-Arroyo, J.2
Abbate, A.3
Bogaard, H.J.4
Nicolls, M.R.5
-
44
-
-
33747497014
-
Interstitial lung disease: Progress and problems
-
Bourke SJ. Interstitial lung disease: progress and problems. Postgrad Med J 2006; 82: 494–499.
-
(2006)
Postgrad Med J
, vol.82
, pp. 494-499
-
-
Bourke, S.J.1
-
45
-
-
7244237837
-
Validation of echocardiographic methods for assessing left ventricular dysfunction in rats with myocardial infarction
-
Morgan EE, Faulx MD, McElfresh TA, Kung TA, Zawaneh MS, Stanley WC et al. Validation of echocardiographic methods for assessing left ventricular dysfunction in rats with myocardial infarction. Am J Physiol Heart Circ Physiol 2004; 287: H2049–H2053.
-
(2004)
Am J Physiol Heart Circ Physiol
, vol.287
, pp. H2049-H2053
-
-
Morgan, E.E.1
Faulx, M.D.2
McElfresh, T.A.3
Kung, T.A.4
Zawaneh, M.S.5
Stanley, W.C.6
-
46
-
-
0028883179
-
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
-
Miyashita T, Reed JC. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 1995; 80: 293–299.
-
(1995)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
47
-
-
33751116534
-
Ku80 and p53 suppress medulloblastoma that arise independent of Rag-1-induced DSBs
-
Holcomb VB, Vogel H, Marple T, Kornegay RW, Hasty P. Ku80 and p53 suppress medulloblastoma that arise independent of Rag-1-induced DSBs. Oncogene 2006; 25: 7159–7165.
-
(2006)
Oncogene
, vol.25
, pp. 7159-7165
-
-
Holcomb, V.B.1
Vogel, H.2
Marple, T.3
Kornegay, R.W.4
Hasty, P.5
-
48
-
-
67349207122
-
Deleting Ku70 is milder than deleting Ku80 in p53-mutant mice and cells
-
Li H, Choi YJ, Hanes MA, Marple T, Vogel H, Hasty P. Deleting Ku70 is milder than deleting Ku80 in p53-mutant mice and cells. Oncogene 2009; 28: 1875–1878.
-
(2009)
Oncogene
, vol.28
, pp. 1875-1878
-
-
Li, H.1
Choi, Y.J.2
Hanes, M.A.3
Marple, T.4
Vogel, H.5
Hasty, P.6
-
49
-
-
34250315824
-
DNA damage-induced cellular senescence is sufficient to suppress tumorigenesis: A mouse model
-
Van Nguyen T, Puebla-Osorio N, Pang H, Dujka ME, Zhu C. DNA damage-induced cellular senescence is sufficient to suppress tumorigenesis: a mouse model. J Exp Med 2007; 204: 1453–1461.
-
(2007)
J Exp Med
, vol.204
, pp. 1453-1461
-
-
van Nguyen, T.1
Puebla-Osorio, N.2
Pang, H.3
Dujka, M.E.4
Zhu, C.5
-
50
-
-
84862515284
-
Cell cycle-and DNA repair pathway-specific effects of apoptosis on tumor suppression
-
Foster SS, De S, Johnson LK, Petrini JH, Stracker TH. Cell cycle-and DNA repair pathway-specific effects of apoptosis on tumor suppression. Proc Natl Acad Sci USA 2012; 109: 9953–9958.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 9953-9958
-
-
Foster, S.S.1
De, S.2
Johnson, L.K.3
Petrini, J.H.4
Stracker, T.H.5
-
51
-
-
0028859541
-
Bax-deficient mice with lymphoid hyperplasia and male germ cell death
-
Knudson CM, Tung KS, Tourtellotte WG, Brown GA, Korsmeyer SJ. Bax-deficient mice with lymphoid hyperplasia and male germ cell death. Science 1995; 270: 96–99.
-
(1995)
Science
, vol.270
, pp. 96-99
-
-
Knudson, C.M.1
Tung, K.S.2
Tourtellotte, W.G.3
Brown, G.A.4
Korsmeyer, S.J.5
-
52
-
-
34247644813
-
Absence of the proapoptotic Bax protein extends fertility and alleviates age-related health complications in female mice
-
Perez GI, Jurisicova A, Wise L, Lipina T, Kanisek M, Bechard A et al. Absence of the proapoptotic Bax protein extends fertility and alleviates age-related health complications in female mice. Proc Natl Acad Sci USA 2007; 104: 5229–5234.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 5229-5234
-
-
Perez, G.I.1
Jurisicova, A.2
Wise, L.3
Lipina, T.4
Kanisek, M.5
Bechard, A.6
-
53
-
-
84355165246
-
Puma and p21 represent cooperating checkpoints limiting self-renewal and chromosomal instability of somatic stem cells in response to telomere dysfunction
-
Sperka T, Song Z, Morita Y, Nalapareddy K, Guachalla LM, Lechel A et al. Puma and p21 represent cooperating checkpoints limiting self-renewal and chromosomal instability of somatic stem cells in response to telomere dysfunction. Nat Cell Biol 2012; 14: 73–79.
-
(2012)
Nat Cell Biol
, vol.14
, pp. 73-79
-
-
Sperka, T.1
Song, Z.2
Morita, Y.3
Nalapareddy, K.4
Guachalla, L.M.5
Lechel, A.6
-
54
-
-
16244382514
-
The Ku70-binding site of Ku80 is required for the stabilization of Ku70 in the cytoplasm, for the nuclear translocation of Ku80, and for Ku80-dependent DNA repair
-
Koike M, Koike A. The Ku70-binding site of Ku80 is required for the stabilization of Ku70 in the cytoplasm, for the nuclear translocation of Ku80, and for Ku80-dependent DNA repair. Exp Cell Res 2005; 305: 266–276.
-
(2005)
Exp Cell Res
, vol.305
, pp. 266-276
-
-
Koike, M.1
Koike, A.2
-
55
-
-
58049091972
-
Cellular senescence and organismal ageing in the absence of p21(CIP1/WAF1) in ku80(− / −) mice
-
Zhao B, Benson EK, Qiao R, Wang X, Kim S, Manfredi JJ et al. Cellular senescence and organismal ageing in the absence of p21(CIP1/WAF1) in ku80(− / −) mice. EMBO Rep 2009; 10: 71–78.
-
(2009)
EMBO Rep
, vol.10
, pp. 71-78
-
-
Zhao, B.1
Benson, E.K.2
Qiao, R.3
Wang, X.4
Kim, S.5
Manfredi, J.J.6
|