Succinate dehydrogenase and fumarate hydratase: Linking mitochondrial dysfunction and cancer

Oncogene

Volumn 25, Issue 34, 2006, Pages 4675-4682

  King, A ^a   Selak, M A ^a   Gottlieb, E ^a  

^a BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

Author keywords

Apoptosis; Hypoxia inducible factor; Mitochondria; Tumour suppressor genes

Indexed keywords

FUMARATE HYDRATASE; FUMARIC ACID; HYPOXIA INDUCIBLE FACTOR 1; MITOCHONDRIAL ENZYME; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; SUCCINATE DEHYDROGENASE; SUCCINIC ACID; TUMOR SUPPRESSOR PROTEIN;

AEROBIC METABOLISM; APOPTOSIS; CANCER; CARCINOGENESIS; CYTOSOL; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ANALYSIS; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME SUBSTRATE; GLYCOLYSIS; METABOLISM; MITOCHONDRIAL RESPIRATION; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REVIEW; TUMOR RESISTANCE;

FUMARATE HYDRATASE; GENES, TUMOR SUPPRESSOR; HUMANS; MITOCHONDRIA; NEOPLASMS; SUCCINATE DEHYDROGENASE;

EID: 33746930794     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1209594     Document Type: Review

References (60)

1. Ang SO, Chen H, Hirota K, Gordeuk VR, Jelinek J, Guan Y et al. (2002). Nat Genet 32: 614-621.
2. Astuti D, Latif F, Dallol A, Dahia PL, Douglas F, George E et al. (2001). Am J Hum Genet 69: 49-54.
3. Baysal BE. (2003). Trends Endocrinol Metab 14: 453-459.
4. Baysal BE, Ferrell RE, Willett-Brozick JE, Lawrence EC, Myssiorek D, Bosch A et al. (2000). Science 287: 848-851.
5. Baysal BE, Willett-Brozick JE, Filho PA, Lawrence EC, Myers EN, Ferrell RE. (2004). J Med Genet 41: 703-709.
6. Benn DE. (2006). J Clin Endorcrinol Metab 91: 827-836.
7. Briere JJ, Favier J, Benit P, El Ghouzzi V, Lorenzato A, Rabier D et al. (2005). Hum Mol Genet 14: 3263-3269.
8. Carew JS, Huang P. (2002). Mol Cancer 1: 9.
9. Chau NM, Rogers P, Aherne W, Carroll V, Collins I, McDonald E et al. (2005). Cancer Res 65: 4918-4928.
10. Dahia PL. (2006). Curr Opin Oncol 18: 1-8.
11. Dahia PLM, Ross KN, Wright ME, Hayashida CY, Santagata S, Barontini M et al. (2005). PLoS Geneti 1: e8.
12. Dang CV, Semenza GL. (1999). Trends Biochem Sci 24: 68-72.
13. Dann III CE, Bruick RK. (2005). Biochem Biophys Res Commun 338: 639-647.
14. Douwes Dekker PB, Hogendoorn PC, Kuipers-Dijkshoorn N, Prins FA, van Duinen SG, Taschner PE et al. (2003). J Pathol 201: 480-486.
15. Elson DA, Thurston G, Huang LE, Ginzinger DG, McDonald DM, Johnson RS et al. (2001). Genes Dev 15: 2520-2532.
16. Eng C, Kiuru M, Fernandez MJ, Aaltonen LA. (2003). Nat Rev Cancer 3: 193-202.
17. Favier J, Briere JJ, Strompf L, Amar L, Filali M, Jeunemaitre X et al. (2005). Horm Res 63: 171-179.
18. Gatenby RA, Gillies RJ. (2004). Nat Rev Cancer 4: 891-899.
19. Gerald D, Berra E, Frapart YM, Chan DA, Giaccia AJ, Mansuy D et al. (2004). Cell 118: 781-794.
20. Gimenez-Roqueplo AP, Favier J, Rustin P, Mourad JJ, Plouin PF, Corvol P et al. (2001). Am J Hum Genet 69: 1186-1197.
21. Gimenez-Roqueplo AP, Favier J, Rustin P, Rieubland C, Kerlan V, Plouin PF et al. (2002). J Clin Endocrinol Metab 87: 4771-4774.
22. Gottlieb E, Tomlinson IP. (2005). Nat Rev Cancer 5: 857-866.
23. Green DR, Kroemer G. (2005). J Clin Invest 115: 2610-2617.
24. Hammerman PS, Fox CJ, Thompson CB. (2004). Trends Biochem Sci 29: 586-592.
25. Hewitson KS, Schofield CJ. (2004). Drug Discov Today 9: 704-711.
26. Hoffman MA, Ohh M, Yang H, Klco JM, Ivan M, Kaelin Jr WG. (2001). Hum Mol Genet 10: 1019-1027.
27. Inoki K, Corradetti MN, Guan KL. (2005). Nat Genet 37: 19-24.
28. Isaacs JS, Jung YJ, Mole DR, Lee S, Torres-Cabala C, Chung YL et al. (2005). Cancer Cell 8: 143-153.
29. Ishii N, Fujii M, Hartman PS, Tsuda M, Yasuda K, Senoo-Matsuda N et al. (1998). Nature 394: 694-697.
30. Ishii T, Yasuda K, Akatsuka A, Hino O, Hartman PS, Ishii N. (2005). Cancer Res 65: 203-209.
31. Kim WY, Kaelin WG. (2004). J Clin Oncol 22: 4991-5004.
32. Kung AL, Zabludoff SD, France DS, Freedman SJ, Tanner EA, Vieira A et al. (2004). Cancer Cell 6: 33-43.
33. Lee S, Nakamura E, Yang H, Wei W, Linggi MS, Sajan MP et al. (2005). Cancer Cell 8: 155-167.
34. Lehtonen R, Kiuru M, Vanharanta S, Sjoberg J, Aaltonen LM, Aittomaki K et al. (2004). Am J Pathol 164: 17-22.
35. Maxwell PH. (2005a). Semin Cell Dev Biol 16: 523-530.
36. Maxwell PH. (2005b). Exp Physiol 90: 791-797.
37. Modica-Napolitano JS, Singh KK. (2004). Mitochondrion 4: 755-762.
38. Neumann HP, Pawlu C, Peczkowska M, Bausch B, McWhinney SR, Muresan M et al. (2004). JAMA 292: 943-951.
39. Niemann S, Muller U. (2000). Nat Genet 26: 268-270.
40. Owen OE, Kalhan SC, Hanson RW. (2002). J Biol Chem 277: 30409-30412.
41. Pawlu C, Bausch B, Neumann HP. (2005). Fam Cancer 4: 49-54.
42. Percy MJ. (2006). Proc Natl Acad Sci USA 103: 654-659.
43. Plas DR, Thompson CB. (2005). Oncogene 24: 7435-7442.
44. Pollard P, Wortham N, Barclay E, Alam A, Elia G, Manek S et al. (2005a). J Pathol 205: 41-49.
45. Pollard PJ, Briere JJ, Alam NA, Barwell J, Barclay E, Wortham NC et al. (2005b). Hum Mol Genet 14: 2231-2239.
46. Raha S, Robinson BH. (2000). Trends Biochem Sci 25: 502-508.
47. Robey RB, Hay N. (2005). Cell Cycle 4: 654-658.
48. Rustin P, Rotig A. (2002). Biochim Biophys Acta 1553: 117-122.
49. Schiavi F, Boedeker CC, Bausch B, Peczkowska M, Gomez CF, Strassburg T et al. (2005). JAMA 294: 2057-2063.
50. Schofield CJ, Ratcliffe PJ. (2004). Nat Rev Mol Cell Biol 5: 343-354.
51. Schofield CJ, Ratcliffe PJ. (2005). Biochem Biophys Res Commun 338: 617-626.
52. Selak MA, Armour SM, MacKenzie ED, Boulahbel H, Watson DG, Mansfield KD et al. (2005). Cancer Cell 7: 77-85.
53. Senoo-Matsuda N, Yasuda K, Tsuda M, Ohkubo T, Yoshimura S, Nakazawa H et al. (2001). J Biol Chem 276: 41553-41558.
54. Tomlinson IP, Alam NA, Rowan AJ, Barclay E, Jaeger EE, Kelsell D et al. (2002). Nat Genet 30: 406-410.
55. Vanharanta S, Buchta M, McWhinney SR, Virta SK, Peczkowska M, Morrison CD et al. (2004). Am J Hum Genet 74: 153-159.
56. Vanharanta S, Pollard PJ, Lehtonen HJ, Laiho P, Sjoberg J, Leminen A et al. (2006). Hum Mol Genet 15: 97-103.
57. Wei MH, Toure O, Glenn GM, Pithukpakorn M, Neckers L, Stolle C et al. (2006). J Med Genet 43: 18-27.
58. Welsh S, Williams R, Kirkpatrick L, Paine-Murrieta G, Powis G. (2004). Mol Cancer Ther 3: 233-244.
59. Yankovskaya V, Horsefield R, Tornroth S, Luna-Chavez C, Miyoshi H, Leger C et al. (2003). Science 299: 700-704.
60. Zu XL, Guppy M. (2004). Biochem Biophys Res Commun 313: 459-465.