-
7
-
-
0029862873
-
Cancer risk in families with hereditary nonpolyposis colorectal cancer diagnosed by mutation analysis
-
(1996)
Gastroenterology
, vol.110
, pp. 1020-1027
-
-
Vasen, H.F.A.1
Wijnen, J.T.2
Menko, F.H.3
Kleibeuker, J.H.4
Taal, B.G.5
Griffioen, G.6
Nagengast, F.M.7
Meijers-Heijboer, E.H.8
Bertario, L.9
Varesco, L.10
Bisgaard, M.-L.11
Mohr, J.12
Fodde, R.13
Meera Khan, P.14
-
8
-
-
0032941343
-
Cancer risk in mutation carriers of DNA mismatch repair genes
-
(1999)
Int. J. Cancer
, vol.81
, pp. 214-218
-
-
Aarnio, M.1
Sankila, R.2
Pukkala, E.3
Salovaara, R.4
Aaltonen, L.A.5
De la Chapelle, A.6
Peltomäki, P.7
Mecklin, J.-P.8
Järvinen, H.J.9
-
11
-
-
0001628596
-
Familial endometrial cancer in female carriers of MSH6 germline mutations
-
(1999)
Nat. Genet.
, vol.23
, pp. 142-144
-
-
Wijnen, J.1
De Leeuw, W.2
Vasen, H.3
Van der Klift, H.4
Møller, P.5
Stormorken, A.6
Meijers-Heijboer, H.7
Lindhout, D.8
Menko, F.9
Vossen, S.10
Möslein, G.11
Tops, C.12
Bröcker-Vriends, A.13
Wu, Y.14
Hofstra, R.15
Sijmons, R.16
Cornelisse, C.17
Morreau, H.18
Fodde, R.19
-
12
-
-
0028785602
-
A transforming growth factor β receptor type II gene mutation common in colon and gastric but rare in endometrial cancers
-
(1995)
Cancer Res.
, vol.55
, pp. 5545-5547
-
-
Myeroff, L.L.1
Parsons, R.2
Kim, S.-J.3
Hedrick, L.4
Cho, K.R.5
Orth, K.6
Mathis, M.7
Kinzler, K.W.8
Lutterbaugh, J.9
Park, K.10
Bang, Y.-J.11
Lee, H.Y.12
Park, J.-G.13
Lynch, H.T.14
Roberts, A.B.15
Vogelstein, B.16
Markowitz, S.D.17
-
17
-
-
0028887597
-
Increased mutation rate at the hprt locus accompanies microsatellite instability in colon cancer
-
(1995)
Oncogene
, vol.10
, pp. 33-37
-
-
Eshleman, J.R.1
Lang, E.Z.2
Bowerfind, G.K.3
Parsons, R.4
Vogelstein, B.5
Willson, J.K.6
Veigl, M.L.7
Sedwick, W.D.8
Markowitz, S.D.9
-
18
-
-
0010945939
-
APC mutations in colorectal tumors with mismatch repair deficiency
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 9049-9054
-
-
Huang, J.1
Papadopoulos, N.2
McKinley, A.J.3
Farrington, S.M.4
Curtis, L.J.5
Wyllie, A.H.6
Zheng, S.7
Willson, J.K.8
Markowitz, S.D.9
Morin, P.10
Kinzler, K.W.11
Vogelstein, B.12
Dunlop, M.G.13
-
19
-
-
0030054532
-
Molecular nature of colon tumors in hereditary nonpolyposis colon cancer, familial polyposis, and sporadic colon cancer
-
(1996)
Gastroenterology
, vol.111
, pp. 307-317
-
-
Konishi, M.1
Kikuchi-Yanoshita, R.2
Tanaka, K.3
Muraoka, M.4
Onda, A.5
Okumura, Y.6
Kishi, N.7
Iwama, T.8
Mori, T.9
Koike, M.10
Ushio, K.11
Chiba, M.12
Nomizu, S.13
Konishi, F.14
Utsunomiya, J.15
Miyaki, M.16
-
20
-
-
0032534069
-
Development of international criteria for the determination of microsatellite instability in colorectal cancer
-
Proceedings of the National Cancer Institute Workshop on Microsatellite Instability for Cancer Detection and Familial Predisposition
-
(1998)
Cancer Res.
, vol.58
, pp. 5248-5257
-
-
Boland, C.R.1
Thibodeau, S.N.2
Hamilton, S.R.3
Sidransky, D.4
Eshleman, J.R.5
Burt, R.W.6
Meltzer, S.J.7
Rodriguez-Bigas, M.A.8
Fodde, R.9
Ranzani, G.N.10
Srivastava, S.11
-
22
-
-
0342872001
-
MSH2 and MLH1 mutations in sporadic replication-error positive colorectal carcinoma as assessed by two-dimensional DNA electrophoresis
-
(1997)
Genes Chrom. Cancer
, vol.18
, pp. 269-278
-
-
Wu, Y.1
Nyström-Lahti, M.2
Osinga, J.3
Looman, M.W.G.4
Peltomäki, P.5
Aaltonen, L.6
De la Chapelle, A.7
Hofstra, R.M.W.8
Buys, C.H.C.M.9
-
24
-
-
0031017268
-
Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cells
-
(1997)
Cancer Res.
, vol.57
, pp. 808-811
-
-
Kane, M.F.1
Loda, M.2
Gaida, G.M.3
Lipman, J.4
Mishra, R.5
Goldman, H.6
Jessup, J.M.7
Kolodner, R.8
-
25
-
-
13144266670
-
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 6870-6875
-
-
Herman, J.G.1
Umar, A.2
Polyak, K.3
Graff, J.R.4
Ahuja, N.5
Issa, J.-P.6
Markowitz, S.7
Willson, J.K.V.8
Hamilton, S.R.9
Kinzler, K.W.10
Kane, M.F.11
Kolodner, R.D.12
Vogelstein, B.13
Kunkel, T.A.14
Baylin, S.B.15
-
26
-
-
13144307115
-
Biallelic inactivation of hMLH1 by epigenetic silencing, a novel mechanism causing human MSI cancers
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 8698-8702
-
-
Veigl, M.L.1
Kasturi, L.2
Olechnowicz, J.3
Ma, A.H.4
Lutterbaugh, J.D.5
Periyasamy, S.6
Li, G.-M.7
Drummond, J.8
Modrich, P.9
Sedwick, W.D.10
Markowitz, S.D.11
-
27
-
-
0028152314
-
Loss of the wild type MLH1 gene is a feature of hereditary nonpolyposis colorectal cancer
-
(1994)
Nat. Genet.
, vol.8
, pp. 405-410
-
-
Hemminki, A.1
Peltomäki, P.2
Mecklin, J.P.3
Järvinen, H.4
Salovaara, R.5
Nyström-Lahti, M.6
De la Chapelle, A.7
Aaltonen, L.A.8
-
31
-
-
0031278322
-
Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancer
-
(1997)
Nat. Genet.
, vol.17
, pp. 271-272
-
-
Miyaki, M.1
Konishi, M.2
Tanaka, K.3
Kikuchi-Yanoshita, R.4
Muraoka, M.5
Yasuno, M.6
Igari, T.7
Koike, M.8
Chiba, M.9
Mori, T.10
-
32
-
-
0032749569
-
Germ-line msh6 mutations in colorectal cancer families
-
(1999)
Cancer Res.
, vol.59
, pp. 5068-5074
-
-
Kolodner, R.D.1
Tytell, J.D.2
Schmeits, J.L.3
Kane, M.F.4
Gupta, R.D.5
Weger, J.6
Wahlberg, S.7
Fox, E.A.8
Peel, D.9
Ziogas, A.10
Garber, J.E.11
Syngal, S.12
Anton-Culver, H.13
Li, F.P.14
-
33
-
-
0033361894
-
Association of hereditary nonpolyposis colorectal cancer-related tumors displaying low microsatellite instability with MSH6 germline mutations
-
(1999)
Am. J. Hum. Genet.
, vol.65
, pp. 1291-1298
-
-
Wu, Y.1
Berends, M.J.W.2
Mensink, R.G.J.3
Kempinga, C.4
Sijmons, R.H.5
Van der Zee, A.G.J.6
Hollema, H.7
Kleibeuker, J.H.8
Buys, C.H.C.M.9
Hofstra, R.M.W.10
-
34
-
-
0034652474
-
The DNA mismatch repair genes Msh3 and Msh6 cooperate in intestinal tumor suppression
-
(2000)
Cancer Res.
, vol.60
, pp. 803-807
-
-
Edelmann, W.1
Umar, A.2
Yang, K.3
Heyer, J.4
Kucherlapati, M.5
Lia, M.6
Kneitz, B.7
Avdievich, E.8
Fan, K.9
Wong, E.10
Crouse, G.11
Kunkel, T.12
Lipkin, M.13
Kolodner, R.D.14
Kucherlapati, R.15
-
35
-
-
0027933070
-
Mutations of two PMS homologues in hereditary nonpolyposis colon cancer
-
(1994)
Nature
, vol.371
, pp. 75-80
-
-
Nicolaides, N.C.1
Papadopoulos, N.2
Liu, B.3
Wei, Y.-F.4
Carter, K.C.5
Ruben, S.M.6
Rosen, C.A.7
Haseltine, W.A.8
Fleischmann, R.D.9
Fraser, C.M.10
Adams, M.D.11
Venter, J.C.12
Dunlop, M.G.13
Hamilton, S.R.14
Petersen, G.M.15
De la Chapelle, A.16
Vogelstein, B.17
Kinzler, K.W.18
-
36
-
-
0028970197
-
The molecular basis of Turcot's syndrome
-
(1995)
N. Engl. J. Med.
, vol.332
, pp. 839-847
-
-
Hamilton, S.R.1
Liu, B.2
Parsons, R.E.3
Papadopoulos, N.4
Jen, J.5
Powell, S.M.6
Krush, A.J.7
Berk, T.8
Cohen, Z.9
Tetu, B.10
Burger, P.C.11
Wood, P.A.12
Taqi, F.13
Booker, S.V.14
Petersen, G.M.15
Offerhaus, J.A.16
Tersmette, A.C.17
Giardiello, F.M.18
Vogelstein, B.19
Kinzler, K.W.20
more..
-
37
-
-
0034720296
-
Somatic mutation of hPMS2 as a possible cause of sporadic human colon cancer with microsatellite instability
-
(2000)
Oncogene
, vol.19
, pp. 2249-2256
-
-
Ma, A.H.1
Xia, L.2
Littman, S.J.3
Swinler, S.4
Lader, G.5
Polinkovsky, A.6
Olechnowicz, J.7
Kasturi, L.8
Lutterbaugh, J.9
Modrich, P.10
Veigl, M.L.11
Markowitz, S.D.12
Sedwick, W.D.13
-
39
-
-
0034642605
-
Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer
-
(2000)
N. Engl. J. Med.
, vol.342
, pp. 69-77
-
-
Gryfe, R.1
Kim, H.2
Hsieh, E.T.K.3
Aronson, M.D.4
Holowaty, E.J.5
Bull, S.B.6
Redston, M.7
Gallinger, S.8
-
40
-
-
0033021439
-
High prevalence of activated intraepithelial cytotoxic T lymphocytes and increased neoplastic cell apoptosis in colorectal carcinomas with microsatellite instability
-
(1999)
Am. J. Pathol.
, vol.154
, pp. 1805-1813
-
-
Dolcetti, R.1
Viel, A.2
Doglioni, C.3
Russo, A.4
Guidoboni, M.5
Capozzi, E.6
Vecchiato, N.7
Macri, E.8
Fornasarig, M.9
Boiocchi, M.10
-
41
-
-
0027136828
-
Genomic instability in colorectal cancer: Relationship to clinicopathological variables and family history
-
(1993)
Cancer Res.
, vol.53
, pp. 5849-5882
-
-
Lothe, R.A.1
Peltomäki, P.2
Meling, G.I.3
Aaltonen, L.A.4
Nyström-Lahti, M.5
Pylkkänen, L.6
Heimdal, K.7
Andersen, T.I.8
Møller, P.9
Rognum, T.O.10
Fosså, S.D.11
Haldorsen, T.12
Langmark, F.13
Brøgger, A.14
De la Chapelle, A.15
Børresen, A.-L.16
-
43
-
-
0029111463
-
MSH2 deficient mice are viable and susceptible to lymphoid tumours
-
(1995)
Nat. Genet.
, vol.11
, pp. 64-70
-
-
Reitmair, A.H.1
Schmits, R.2
Ewel, A.3
Bapat, B.4
Redston, M.5
Mitri, A.6
Waterhouse, P.7
Mittrücker, H.-W.8
Wakeham, A.9
Liu, B.10
Thomason, A.11
Griesser, H.12
Gallinger, S.13
Ballhausen, W.G.14
Fishel, R.15
Mak, T.W.16
-
44
-
-
0029101616
-
Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer
-
(1995)
Cell
, vol.82
, pp. 321-330
-
-
De Wind, N.1
Dekker, M.2
Berns, A.3
Radman, M.4
Te Riele, H.5
-
45
-
-
8944232867
-
Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over
-
(1996)
Nat. Genet.
, vol.13
, pp. 336-342
-
-
Baker, S.M.1
Plug, A.W.2
Prolla, T.A.3
Bronner, C.E.4
Harris, A.C.5
Yao, X.6
Christie, D.-M.7
Monell, C.8
Arnheim, N.9
Bradley, A.10
Ashley, T.11
Liskay, R.M.12
-
46
-
-
0031882250
-
Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repair
-
(1998)
Nat. Genet.
, vol.18
, pp. 276-279
-
-
Prolla, T.A.1
Baker, S.M.2
Harris, A.C.3
Tsao, J.-L.4
Yao, X.5
Bronner, C.E.6
Zheng, B.7
Gordon, M.8
Reneker, J.9
Arnheim, N.10
Shibata, D.11
Bradley, A.12
Liskay, R.M.13
-
47
-
-
0030709433
-
Mutation in the mismatch repair gene Msh6 causes cancer susceptibility
-
(1997)
Cell
, vol.91
, pp. 467-477
-
-
Edelmann, W.1
Yang, K.2
Umar, A.3
Heyer, J.4
Lau, K.5
Fan, K.6
Liedtke, W.7
Cohen, P.E.8
Kane, M.F.9
Lipford, J.R.10
Yu, N.11
Crouse, G.F.12
Pollard, J.W.13
Kunkel, T.14
Lipkin, M.15
Kolodner, R.16
Kucherlapati, R.17
-
48
-
-
0032726607
-
HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions
-
(1999)
Nat. Genet.
, vol.23
, pp. 359-362
-
-
De Wind, N.1
Dekker, M.2
Claij, N.3
Jansen, L.4
Van Klink, Y.5
Radman, M.6
Riggins, G.7
Van der Valk, M.8
Van't Wout, K.9
Te Riele, H.10
-
49
-
-
0029099989
-
Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis
-
(1995)
Cell
, vol.82
, pp. 309-319
-
-
Baker, S.M.1
Bronner, C.E.2
Zhang, L.3
Plug, A.W.4
Robatzek, M.5
Warren, G.6
Elliott, E.A.7
Yu, J.8
Ashley, T.9
Arnheim, N.10
Flavell, R.A.11
Liskay, M.R.12
-
50
-
-
8944262831
-
MSH2 deficiency contributes to accelerated APC-mediated intestinal tumorigenesis
-
(1996)
Cancer Res.
, vol.56
, pp. 2922-2926
-
-
Reitmair, A.H.1
Cai, J.-C.2
Bjerknes, M.3
Redston, M.4
Cheng, H.5
Pind, M.T.L.6
Hay, K.7
Mitri, A.8
Bapat, B.W.9
Mak, T.W.10
Gallinger, S.11
-
51
-
-
0032521201
-
-/-;Min mice
-
(1998)
Cancer Res.
, vol.58
, pp. 1087-1089
-
-
Baker, S.M.1
Harris, A.C.2
Tsao, J.-L.3
Flath, T.J.4
Bronner, C.E.5
Gordon, M.6
Shibata, D.7
Liskay, R.M.8
-
54
-
-
0032578544
-
Mouse embryonic stem cells carrying one or two defective Msh2 alleles respond abnormally to oxidative stress inflicted by low-level radiation
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 11915-11920
-
-
DeWeese, T.L.1
Shipman, J.M.2
Larrier, N.A.3
Buckley, N.M.4
Kidd, L.C.R.5
Groopman, J.D.6
Cutler, R.G.7
Te Riele, H.8
Nelson, W.G.9
-
65
-
-
0031855988
-
Enrichment for DNA mismatch repair-deficient cells during treatment with cisplatin
-
(1998)
Int. J. Cancer
, vol.77
, pp. 741-746
-
-
Fink, D.1
Nebel, S.2
Norris, P.S.3
Baergen, R.N.4
Wilczynski, S.P.5
Costa, J.M.6
Haas, M.7
Cannistra, S.A.8
Howell, S.B.9
-
66
-
-
0030606299
-
Suppression of intestinal polyposis in ApcΔ716 knockout mice by inhibition of cyclooxygenase 2 (COX2)
-
(1996)
Cell
, vol.87
, pp. 803-809
-
-
Oshima, M.1
Dinchuk, J.E.2
Kargman, S.L.3
Oshima, H.4
Hancock, B.5
Kwong, E.6
Trzaskos, J.M.7
Evans, J.F.8
Taketo, M.M.9
-
68
-
-
3643084354
-
Reduced COX2 protein in colorectal cancer with defective mismatch repair
-
(1998)
Cancer Res.
, vol.58
, pp. 5473-5477
-
-
Karnes W.E., Jr.1
Shattuck-Brandt, R.2
Burgart, L.J.3
DuBois, R.N.4
Tester, D.J.5
Cunningham, J.M.6
Kim, C.Y.7
McDonnell, S.K.8
Schaid, D.J.9
Thibodeau, S.N.10
|