Potassium channel subfamily K member 3 (KCNK3) contributes to the development of pulmonary arterial hypertension

Circulation

Volumn 133, Issue 14, 2016, Pages 1371-1385

  Antigny, Fabrice ^a,b,c   Hautefort, Aurélie ^a,b,c   Meloche, Jolyane ^e   Belacel Ouari, Milia ^d   Manoury, Boris ^d   Rucker Martin, Catherine ^a,b,c   Péchoux, Christine ^f   Potus, François ^e   Nadeau, Valérie ^e   Tremblay, Eve ^e   Ruffenach, Grégoire ^e   Bourgeois, Alice ^e   Dorfmüller, Peter ^a,b,c   Breuils Bonnet, Sandra ^e   Fadel, Elie ^a,b,c,f,g   Ranchoux, Benoît ^a,b,c   Jourdon, Philippe ^a,b,c   Girerd, Barbara ^a,b,c   Montani, David ^a,b,c   Provencher, Steeve ^e   Bonnet, Sébastien ^e   Simonneau, Gérald ^a,b,c   Humbert, Marc ^a,b,c   Perros, Frédéric ^a,b,c,e   more..

^a UNIVERSITÉ PARIS SACLAY   (France)

^b BICÊTRE HOSPITAL   (France)

^c Universite Paris Sud   (France)

^d INSERM   (France)

^e LAVAL UNIVERSITY   (Canada)

^f UMR1313 GÉNÉTIQUE ANIMALE ET BIOLOGIE INTÉGRATIVE   (France)

^g CENTRE CHIRURGICAL MARIE LANNELONGUE   (France)

Author keywords

cell proliferation; electrophysiology; hypertension, pulmonary; ion channels; pulmonary artery

Indexed keywords

2 (4 AMYLCINNAMIDO) 4 CHLOROBENZOIC ACID; 2 (BUTANE 1 SULFONYL AMINO) N [1 (6 METHOXYPYRIDIN 3 YL) PROPYL]BENZAMIDE; MONOCROTALINE; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL KCNK3; UNCLASSIFIED DRUG; 2-(BUTANE-1-SULFONYLAMINO)-N-(1-(6-METHOXYPYRIDIN-3-YL)PROPYL)BENZAMIDE; ANTHRANILIC ACID DERIVATIVE; BMPR2 PROTEIN, HUMAN; BONE MORPHOGENETIC PROTEIN RECEPTOR 2; NERVE PROTEIN; POTASSIUM CHANNEL SUBFAMILY K MEMBER 3; SULFONAMIDE; TANDEM PORE DOMAIN POTASSIUM CHANNEL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY ENDOTHELIUM; ARTERY TONE; ARTICLE; CELL ISOLATION; CELL MEMBRANE DEPOLARIZATION; CELL PROLIFERATION; CONTROLLED STUDY; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; MONOCROTALINE-INDUCED PULMONARY HYPERTENSION; NONHUMAN; PATCH CLAMP TECHNIQUE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PULMONARY ARTERY SMOOTH MUSCLE CELL; PULMONARY HYPERTENSION; RAT; ADVENTITIA; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CELL DIVISION; CHEMICALLY INDUCED; COMPLICATION; GENETIC PREDISPOSITION; GENETICS; HEMODYNAMICS; HYPERTROPHY, RIGHT VENTRICULAR; INFLAMMATION; MALE; MEMBRANE POTENTIAL; MUTATION; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SMOOTH MUSCLE CELL; SPRAGUE DAWLEY RAT; VASCULAR ENDOTHELIUM; VASCULAR RESISTANCE; WISTAR RAT;

ADVENTITIA; ANIMALS; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE II; CELL DIVISION; ENDOTHELIUM, VASCULAR; FIBROBLASTS; GENETIC PREDISPOSITION TO DISEASE; HEMODYNAMICS; HUMANS; HYPERTENSION, PULMONARY; HYPERTROPHY, RIGHT VENTRICULAR; INFLAMMATION; MALE; MEMBRANE POTENTIALS; MONOCROTALINE; MUTATION; MYOCYTES, SMOOTH MUSCLE; NERVE TISSUE PROTEINS; ORTHO-AMINOBENZOATES; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS, TANDEM PORE DOMAIN; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; SULFONAMIDES; VASCULAR RESISTANCE;

EID: 84959213145     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.115.020951     Document Type: Article

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