Apurinic/apyrimidinic (AP) site recognition by the 5′-dRP/AP lyase in poly(ADP-ribose) polymerase-1 (PARP-1)

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 51, 2010, Pages 22090-22095

  Khodyreva, S N ^a   Prasad, R ^b   Ilina, E S ^a   Sukhanova, M V ^a   Kutuzov, M M ^a   Liu, Y ^b   Hou, E W ^b   Wilson, S H ^b   Lavrik, O I ^a  

^a INSTITUTE OF CHEMICAL BIOLOGY AND FUNDAMENTAL MEDICINE   (Russian Federation)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Apurinic apyrimidinic site binding protein; Schiff base

Indexed keywords

5' DEOXYRIBOSE PHOSPHATE; CELL EXTRACT; DEOXYRIBOSE; DNA; LYASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; POLY(ADENOSINE DIPHOSPHATE RIBOSE); SODIUM BOROHYDRIDE; UNCLASSIFIED DRUG;

APURINIC SITE; APYRIMIDINIC SITE; ARTICLE; CONTROLLED STUDY; COVALENT BOND; DNA CROSS LINKING; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MASS SPECTROMETRY; MOLECULAR RECOGNITION; PRIORITY JOURNAL; REDUCTION;

BINDING SITES; BOROHYDRIDES; DNA; DNA REPAIR; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; ENZYME ACTIVATION; HELA CELLS; HUMANS; OXIDATION-REDUCTION; POLY ADENOSINE DIPHOSPHATE RIBOSE; POLY(ADP-RIBOSE) POLYMERASES;

EID: 78650670562     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1009182107     Document Type: Article

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