-
1
-
-
84858308226
-
Natural products as sources of new drugs over the 30 years from 1981 to 2010
-
[1] Newman, D. J.; Cragg, G. M. “Natural products as sources of new drugs over the 30 years from 1981 to 2010” J. Nat. Prod. 2012, 75, 311.
-
(2012)
J. Nat. Prod
, vol.75
, pp. 311
-
-
Newman, D.J.1
Cragg, G.M.2
-
2
-
-
0000378637
-
On the antibacterial action of cultures of a Penicillium, with special reference to their use in the isolation of B. Influenzae
-
Fleming, A. “On the antibacterial action of cultures of a Penicillium, with special reference to their use in the isolation of B. Influenzae.” Br. J. Exp. Pathol. 1929, 10, 226.
-
(1929)
Br. J. Exp. Pathol
, vol.10
, pp. 226
-
-
Fleming, A.1
-
3
-
-
33750503724
-
Control of gram-negative bacteria in experimental animals by streptomycin
-
Jones, D.; Metzger, H. J.; Schatz, A.; Waksman, S. A. “Control of gram-negative bacteria in experimental animals by streptomycin” Science 1944, 100, 103.
-
(1944)
Science
, vol.100
, pp. 103
-
-
Jones, D.1
Metzger, H.J.2
Schatz, A.3
Waksman, S.A.4
-
4
-
-
84964127707
-
Effect of streptomycin and other antibiotic substances upon Mycobacterium tuberculosis and related organisms
-
Schatz, A.; Waksman, S. A. “Effect of streptomycin and other antibiotic substances upon Mycobacterium tuberculosis and related organisms” Proc. Soc. Exp. Biol. Med. 1944, 57, 244.
-
(1944)
Proc. Soc. Exp. Biol. Med
, vol.57
, pp. 244
-
-
Schatz, A.1
Waksman, S.A.2
-
5
-
-
84964134387
-
Streptomycin, a substance exhibiting antibiotic activity against gram positive and gramnegative bacteria
-
Schatz, A.; Bugie, E.; Waksman, S. A. “Streptomycin, a substance exhibiting antibiotic activity against gram positive and gramnegative bacteria” Proc. Soc. Exp. Biol. Med 1944, 55, 66.
-
(1944)
Proc. Soc. Exp. Biol. Med
, vol.55
, pp. 66
-
-
Schatz, A.1
Bugie, E.2
Waksman, S.A.3
-
6
-
-
33745019553
-
Marcel Faber Roundtable: Is our antibiotic pipeline unproductive because of starvation, constipation or lack of inspiration?
-
Baltz, R. H. “Marcel Faber Roundtable: is our antibiotic pipeline unproductive because of starvation, constipation or lack of inspiration?” J. Ind. Microbiol. Biotechnol. 2006, 33, 507.
-
(2006)
J. Ind. Microbiol. Biotechnol
, vol.33
, pp. 507
-
-
Baltz, R.H.1
-
7
-
-
84907581578
-
Update on the antibiotic resistance crisis
-
Rossolini, G. M.; Arena, F.; Pecile, P.; Pollini, S. “Update on the antibiotic resistance crisis” Curr. Opin. Pharmacol. 2014, 18, 56.
-
(2014)
Curr. Opin. Pharmacol
, vol.18
, pp. 56
-
-
Rossolini, G.M.1
Arena, F.2
Pecile, P.3
Pollini, S.4
-
8
-
-
34548108138
-
Targeting virulence: A new paradigm for antimicrobial therapy
-
Clatworthy, A. E.; Pierson, E.; Hung, D. T. “Targeting virulence: a new paradigm for antimicrobial therapy” Nat. Chem. Biol. 2007, 3, 541.
-
(2007)
Nat. Chem. Biol
, vol.3
, pp. 541
-
-
Clatworthy, A.E.1
Pierson, E.2
Hung, D.T.3
-
9
-
-
77955705492
-
Bioactivity-guided navigation of chemical space
-
Bon, R. S.; Waldmann, H. “Bioactivity-guided navigation of chemical space” Acc. Chem. Res. 2010, 43, 1103.
-
(2010)
Acc. Chem. Res
, vol.43
, pp. 1103
-
-
Bon, R.S.1
Waldmann, H.2
-
10
-
-
84865683314
-
Thoughts and facts about antibiotics: Where we are now and where we are heading
-
Berdy, J. “Thoughts and facts about antibiotics: where we are now and where we are heading” J. Antibiot. 2012, 65, 385.
-
(2012)
J. Antibiot
, vol.65
, pp. 385
-
-
Berdy, J.1
-
11
-
-
77955014467
-
Natural products as chemical probes
-
Carlson, E. E. “Natural products as chemical probes” ACS Chem. Biol. 2010, 5, 639.
-
(2010)
ACS Chem. Biol
, vol.5
, pp. 639
-
-
Carlson, E.E.1
-
12
-
-
0034678033
-
Target-oriented and diversity-oriented organic synthesis in drug discovery
-
Schreiber, S. L. “Target-oriented and diversity-oriented organic synthesis in drug discovery” Science 2000, 287, 1964.
-
(2000)
Science
, vol.287
, pp. 1964
-
-
Schreiber, S.L.1
-
13
-
-
48149108752
-
Natural products as an inspiration in the diversity-oriented synthesis of bioactive compound libraries
-
Cordier, C.; Morton, D.; Murrison, S.; Nelson, A.; O’Leary-Steele, C. “Natural products as an inspiration in the diversity-oriented synthesis of bioactive compound libraries” Nat. Prod. Rep. 2008, 25, 719.
-
(2008)
Nat. Prod. Rep
, vol.25
, pp. 719
-
-
Cordier, C.1
Morton, D.2
Murrison, S.3
Nelson, A.4
O’leary-Steele, C.5
-
14
-
-
84862008385
-
Diversityoriented synthesis: Producing chemical tools for dissecting biology
-
O’Connor, C. J.; Beckmann, H. S.; Spring, D. R. “Diversityoriented synthesis: producing chemical tools for dissecting biology” Chem. Soc. Rev. 2012, 41, 4444.
-
(2012)
Chem. Soc. Rev
, vol.41
, pp. 4444
-
-
O’Connor, C.J.1
Beckmann, H.S.2
Spring, D.R.3
-
15
-
-
84875466221
-
A ring-distortion strategy to construct stereochemically complex and structurally diverse compounds from natural products
-
Huigens, R. W., III; Morrison, K. C.; Hicklin, R. W.; Flood, T. A., Jr.; Richter, M. F.; Hergenrother, P. J. “A ring-distortion strategy to construct stereochemically complex and structurally diverse compounds from natural products” Nat. Chem. 2013, 5, 195.
-
(2013)
Nat. Chem
, vol.5
, pp. 195
-
-
Huigens, R.W.1
Morrison, K.C.2
Hicklin, R.W.3
Flood, T.A.4
Richter, M.F.5
Hergenrother, P.J.6
-
16
-
-
84890069342
-
Natural products as starting points for the synthesis of complex and diverse compounds
-
Morrison, K. C.; Hergenrother, P. J. “Natural products as starting points for the synthesis of complex and diverse compounds” Nat. Prod. Rep. 2014, 31, 6.
-
(2014)
Nat. Prod. Rep
, vol.31
, pp. 6
-
-
Morrison, K.C.1
Hergenrother, P.J.2
-
17
-
-
80055018013
-
Natural products and Pharma 2011: Strategic changes spur new opportunities
-
Carter, G. T. “Natural products and Pharma 2011: Strategic changes spur new opportunities” Nat. Prod. Rep. 2011, 28, 1783.
-
(2011)
Nat. Prod. Rep
, vol.28
, pp. 1783
-
-
Carter, G.T.1
-
18
-
-
84907899428
-
Natural product and natural product derived drugs in clinical trials
-
Butler, M. S.; Robertson, A. A.; Cooper, M. A. “Natural product and natural product derived drugs in clinical trials” Nat. Prod. Rep. 2014, 31, 1612.
-
(2014)
Nat. Prod. Rep
, vol.31
, pp. 1612
-
-
Butler, M.S.1
Robertson, A.A.2
Cooper, M.A.3
-
19
-
-
84893490856
-
Lessons learned from the transformation of natural product discovery to a genome-driven endeavor
-
Deane, C. D.; Mitchell, D. A. “Lessons learned from the transformation of natural product discovery to a genome-driven endeavor” J. Ind. Microbiol. Biotechnol. 2014, 41, 315.
-
(2014)
J. Ind. Microbiol. Biotechnol
, vol.41
, pp. 315
-
-
Deane, C.D.1
Mitchell, D.A.2
-
20
-
-
84895072793
-
Microbial genome mining for accelerated natural products discovery: Is a renaissance in the making?
-
Bachmann, B. O.; Van Lanen, S. G.; Baltz, R. H. “Microbial genome mining for accelerated natural products discovery: is a renaissance in the making?” J. Ind. Microbiol. Biotechnol. 2014, 41, 175.
-
(2014)
J. Ind. Microbiol. Biotechnol
, vol.41
, pp. 175
-
-
Bachmann, B.O.1
Van Lanen, S.G.2
Baltz, R.H.3
-
21
-
-
84893460683
-
Challenges and triumphs to genomics-based natural product discovery
-
Jensen, P. R.; Chavarria, K. L.; Fenical, W.; Moore, B. S.; Ziemert, N. “Challenges and triumphs to genomics-based natural product discovery” J. Ind. Microbiol. Biotechnol. 2014, 41, 203.
-
(2014)
J. Ind. Microbiol. Biotechnol
, vol.41
, pp. 203
-
-
Jensen, P.R.1
Chavarria, K.L.2
Fenical, W.3
Moore, B.S.4
Ziemert, N.5
-
22
-
-
0029653518
-
Whole-Genome Random Sequencing and Assembly of Haemophilus influenzae Rd
-
Fleischmann, R. D.; Adams, M. D.; White, O.; Clayton, R. A.; Kirkness, E. F.; Kerlavage, A. R.; Bult, C. J.; Tomb, J. F.; Dougherty, B. A.; Merrick, J. M.; Mckenney, K.; Sutton, G.; Fitzhugh, W.; Fields, C.; Gocayne, J. D.; Scott, J.; Shirley, R.; Liu, L. I.; Glodek, A.; Kelley, J. M.; Weidman, J. F.; Phillips, C. A.; Spriggs, T.; Hedblom, E.; Cotton, M. D.; Utterback, T. R.; Hanna, M. C.; Nguyen, D. T.; Saudek, D. M.; Brandon, R. C.; Fine, L. D.; Fritchman, J. L.; Fuhrmann, J. L.; Geoghagen, N. S. M.; Gnehm, C. L.; Mcdonald, L. A.; Small, K. V.; Fraser, C. M.; Smith, H. O.; Venter, J. C. “Whole-Genome Random Sequencing and Assembly of Haemophilus influenzae Rd” Science 1995, 269, 496.
-
(1995)
Science
, vol.269
, pp. 496
-
-
Fleischmann, R.D.1
Adams, M.D.2
White, O.3
Clayton, R.A.4
Kirkness, E.F.5
Kerlavage, A.R.6
Bult, C.J.7
Tomb, J.F.8
Dougherty, B.A.9
Merrick, J.M.10
McKenney, K.11
Sutton, G.12
Fitzhugh, W.13
Fields, C.14
Gocayne, J.D.15
Scott, J.16
Shirley, R.17
Liu, L.I.18
Glodek, A.19
Kelley, J.M.20
Weidman, J.F.21
Phillips, C.A.22
Spriggs, T.23
Hedblom, E.24
Cotton, M.D.25
Utterback, T.R.26
Hanna, M.C.27
Nguyen, D.T.28
Saudek, D.M.29
Brandon, R.C.30
Fine, L.D.31
Fritchman, J.L.32
Fuhrmann, J.L.33
Geoghagen, N.S.M.34
Gnehm, C.L.35
McDonald, L.A.36
Small, K.V.37
Fraser, C.M.38
Smith, H.O.39
Venter, J.C.40
more..
-
23
-
-
0037046560
-
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)
-
Bentley, S. D.; Chater, K. F.; Cerdeno-Tarraga, A. M.; Challis, G. L.; Thomson, N. R.; James, K. D.; Harris, D. E.; Quail, M. A.; Kieser, H.; Harper, D.; Bateman, A.; Brown, S.; Chandra, G.; Chen, C. W.; Collins, M.; Cronin, A.; Fraser, A.; Goble, A.; Hidalgo, J.; Hornsby, T.; Howarth, S.; Huang, C. H.; Kieser, T.; Larke, L.; Murphy, L.; Oliver, K.; O'Neil, S.; Rabbinowitsch, E.; Rajandream, M. A.; Rutherford, K.; Rutter, S.; Seeger, K.; Saunders, D.; Sharp, S.; Squares, R.; Squares, S.; Taylor, K.; Warren, T.; Wietzorrek, A.; Woodward, J.; Barrell, B. G.; Parkhill, J.; Hopwood, D. A. “Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)” Nature 2002, 417, 141.
-
(2002)
Nature
, vol.417
, pp. 141
-
-
Bentley, S.D.1
Chater, K.F.2
Cerdeno-Tarraga, A.M.3
Challis, G.L.4
Thomson, N.R.5
James, K.D.6
Harris, D.E.7
Quail, M.A.8
Kieser, H.9
Harper, D.10
Bateman, A.11
Brown, S.12
Chandra, G.13
Chen, C.W.14
Collins, M.15
Cronin, A.16
Fraser, A.17
Goble, A.18
Hidalgo, J.19
Hornsby, T.20
Howarth, S.21
Huang, C.H.22
Kieser, T.23
Larke, L.24
Murphy, L.25
Oliver, K.26
O'neil, S.27
Rabbinowitsch, E.28
Rajandream, M.A.29
Rutherford, K.30
Rutter, S.31
Seeger, K.32
Saunders, D.33
Sharp, S.34
Squares, R.35
Squares, S.36
Taylor, K.37
Warren, T.38
Wietzorrek, A.39
Woodward, J.40
Barrell, B.G.41
Parkhill, J.42
Hopwood, D.A.43
more..
-
24
-
-
79851507787
-
Genomics-inspired discovery of natural products
-
Winter, J. M.; Behnken, S.; Hertweck, C. “Genomics-inspired discovery of natural products” Curr. Opin. Chem. Biol. 2011, 15, 22.
-
(2011)
Curr. Opin. Chem. Biol
, vol.15
, pp. 22
-
-
Winter, J.M.1
Behnken, S.2
Hertweck, C.3
-
25
-
-
84893470138
-
Actinomycetes biosynthetic potential: How to bridge in silico and in vivo?
-
Rebets, Y.; Brotz, E.; Tokovenko, B.; Luzhetskyy, A. “Actinomycetes biosynthetic potential: how to bridge in silico and in vivo?” J. Ind. Microbiol. Biotechnol. 2014, 41, 387.
-
(2014)
J. Ind. Microbiol. Biotechnol
, vol.41
, pp. 387
-
-
Rebets, Y.1
Brotz, E.2
Tokovenko, B.3
Luzhetskyy, A.4
-
26
-
-
79851508812
-
Genome mining for ribosomally synthesized natural products
-
Velasquez, J. E.; van der Donk, W. A. “Genome mining for ribosomally synthesized natural products” Curr. Opin. Chem. Biol. 2011, 15, 11.
-
(2011)
Curr. Opin. Chem. Biol
, vol.15
, pp. 11
-
-
Velasquez, J.E.1
van der Donk, W.A.2
-
27
-
-
65549083361
-
Strategies for the discovery of new natural products by genome mining
-
Zerikly, M.; Challis, G. L. “Strategies for the discovery of new natural products by genome mining” ChemBioChem 2009, 10, 625.
-
(2009)
Chembiochem
, vol.10
, pp. 625
-
-
Zerikly, M.1
Challis, G.L.2
-
28
-
-
84903767204
-
Metagenomic small molecule discovery methods
-
Charlop-Powers, Z.; Milshteyn, A.; Brady, S. F. “Metagenomic small molecule discovery methods” Curr. Opin. Microbiol. 2014, 19, 70.
-
(2014)
Curr. Opin. Microbiol
, vol.19
, pp. 70
-
-
Charlop-Powers, Z.1
Milshteyn, A.2
Brady, S.F.3
-
29
-
-
34249907531
-
Strategies to unravel the function of orphan biosynthesis pathways: Recent examples and future prospects
-
Gross, H. “Strategies to unravel the function of orphan biosynthesis pathways: recent examples and future prospects” Appl. Microbiol. Biotechnol. 2007, 75, 267.
-
(2007)
Appl. Microbiol. Biotechnol
, vol.75
, pp. 267
-
-
Gross, H.1
-
30
-
-
84864375028
-
Informatic strategies for the discovery of polyketides and nonribosomal peptides
-
Johnston, C.; Ibrahim, A.; Magarvey, N. “Informatic strategies for the discovery of polyketides and nonribosomal peptides” Medchemcomm 2012, 3, 932.
-
(2012)
Medchemcomm
, vol.3
, pp. 932
-
-
Johnston, C.1
Ibrahim, A.2
Magarvey, N.3
-
31
-
-
84910067865
-
Mining the metabiome: Identifying novel natural products from microbial communities
-
Milshteyn, A.; Schneider, J. S.; Brady, S. F. “Mining the metabiome: identifying novel natural products from microbial communities” Chem. Biol. 2014, 21, 1211.
-
(2014)
Chem. Biol
, vol.21
, pp. 1211
-
-
Milshteyn, A.1
Schneider, J.S.2
Brady, S.F.3
-
32
-
-
77649305354
-
Natural products version 2.0: Connecting genes to molecules
-
Walsh, C. T.; Fischbach, M. A. “Natural products version 2.0: connecting genes to molecules” J. Am. Chem. Soc. 2010, 132, 2469.
-
(2010)
J. Am. Chem. Soc
, vol.132
, pp. 2469
-
-
Walsh, C.T.1
Fischbach, M.A.2
-
33
-
-
27544477567
-
Discovery of a new peptide natural product by Streptomyces coelicolor genome mining
-
Lautru, S.; Deeth, R. J.; Bailey, L. M.; Challis, G. L. “Discovery of a new peptide natural product by Streptomyces coelicolor genome mining” Nat. Chem. Biol. 2005, 1, 265.
-
(2005)
Nat. Chem. Biol
, vol.1
, pp. 265
-
-
Lautru, S.1
Deeth, R.J.2
Bailey, L.M.3
Challis, G.L.4
-
34
-
-
2442615925
-
Genome mining to identify new plant triterpenoids
-
Fazio, G. C.; Xu, R.; Matsuda, S. P. T. “Genome mining to identify new plant triterpenoids” J. Am. Chem. Soc. 2004, 126, 5678.
-
(2004)
J. Am. Chem. Soc
, vol.126
, pp. 5678
-
-
Fazio, G.C.1
Xu, R.2
Matsuda, S.3
-
35
-
-
1842713162
-
Genome-inspired search for new antibiotics. Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34
-
Tohyama, S.; Eguchi, T.; Dhakal, R. P.; Akashi, T.; Otsuka, M.; Kakinuma, K. “Genome-inspired search for new antibiotics. Isolation and structure determination of new 28-membered polyketide macrolactones, halstoctacosanolides A and B, from Streptomyces halstedii HC34” Tetrahedron 2004, 60, 3999.
-
(2004)
Tetrahedron
, vol.60
, pp. 3999
-
-
Tohyama, S.1
Eguchi, T.2
Dhakal, R.P.3
Akashi, T.4
Otsuka, M.5
Kakinuma, K.6
-
36
-
-
15744396410
-
Structure and biosynthesis of myxochromides S1-3 in Stigmatella aurantiaca: Evidence for an iterative bacterial type I polyketide synthase and for module skipping in nonribosomal peptide biosynthesis
-
Wenzel, S. C.; Kunze, B.; Hofle, G.; Silakowski, B.; Scharfe, M.; Blocker, H.; Muller, R. “Structure and biosynthesis of myxochromides S1-3 in Stigmatella aurantiaca: Evidence for an iterative bacterial type I polyketide synthase and for module skipping in nonribosomal peptide biosynthesis” ChemBioChem 2005, 6, 375.
-
(2005)
Chembiochem
, vol.6
, pp. 375
-
-
Wenzel, S.C.1
Kunze, B.2
Hofle, G.3
Silakowski, B.4
Scharfe, M.5
Blocker, H.6
Muller, R.7
-
37
-
-
42949136443
-
Genome mining for novel natural product discovery
-
Challis, G. L. “Genome mining for novel natural product discovery” J. Med. Chem. 2008, 51, 2618.
-
(2008)
J. Med. Chem
, vol.51
, pp. 2618
-
-
Challis, G.L.1
-
38
-
-
84939557642
-
Minimum Information about a Biosynthetic Gene cluster
-
Medema, M. H.; Kottmann, R.; Yilmaz, P.; Cummings, M.; Biggins, J. B.; Blin, K.; de Bruijn, I.; Chooi, Y. H.; Claesen, J.; Coates, R. C.; Cruz-Morales, P.; Duddela, S.; Dusterhus, S.; Edwards, D. J.; Fewer, D. P.; Garg, N.; Geiger, C.; Gomez- Escribano, J. P.; Greule, A.; Hadjithomas, M.; Haines, A. S.; Helfrich, E. J. N.; Hillwig, M. L.; Ishida, K.; Jones, A. C.; Jones, C. S.; Jungmann, K.; Kegler, C.; Kim, H. U.; Kotter, P.; Krug, D.; Masschelein, J.; Melnik, A. V.; Mantovani, S. M.; Monroe, E. A.; Moore, M.; Moss, N.; Nutzmann, H.-W.; Pan, G.; Pati, A.; Petras, D.; Reen, F. J.; Rosconi, F.; Rui, Z.; Tian, Z.; Tobias, N. J.; Tsunematsu, Y.; Wiemann, P.; Wyckoff, E.; Yan, X.; Yim, G.; Yu, F.; Xie, Y.; Aigle, B.; Apel, A. K.; Balibar, C. J.; Balskus, E. P.; Barona-Gomez, F.; Bechthold, A.; Bode, H. B.; Borriss, R.; Brady, S. F.; Brakhage, A. A.; Caffrey, P.; Cheng, Y.-Q.; Clardy, J.; Cox, R. J.; De Mot, R.; Donadio, S.; Donia, M. S.; van der Donk, W. A.; Dorrestein, P. C.; Doyle, S.; Driessen, A. J. M.; Ehling-Schulz, M.; Entian, K.-D.; Fischbach, M. A.; Gerwick, L.; Gerwick, W. H.; Gross, H.; Gust, B.; Hertweck, C.; Hofte, M.; Jensen, S. E.; Ju, J.; Katz, L.; Kaysser, L.; Klassen, J. L.; Keller, N. P.; Kormanec, J.; Kuipers, O. P.; Kuzuyama, T.; Kyrpides, N. C.; Kwon, H.-J.; Lautru, S.; Lavigne, R.; Lee, C. Y.; Linquan, B.; Liu, X.; Liu, W.; Luzhetskyy, A.; Mahmud, T.; Mast, Y.; Mendez, C.; Metsa-Ketela, M.; Micklefield, J.; Mitchell, D. A.; Moore, B. S.; Moreira, L. M.; Muller, R.; Neilan, B. A.; Nett, M.; Nielsen, J.; O'Gara, F.; Oikawa, H.; Osbourn, A.; Osburne, M. S.; Ostash, B.; Payne, S. M.; Pernodet, J.-L.; Petricek, M.; Piel, J.; Ploux, O.; Raaijmakers, J. M.; Salas, J. A.; Schmitt, E. K.; Scott, B.; Seipke, R. F.; Shen, B.; Sherman, D. H.; Sivonen, K.; Smanski, M. J.; Sosio, M.; Stegmann, E.; Sussmuth, R. D.; Tahlan, K.; Thomas, C. M.; Tang, Y.; Truman, A. W.; Viaud, M.; Walton, J. D.; Walsh, C. T.; Weber, T.; van Wezel, G. P.; Wilkinson, B.; Willey, J. M.; Wohlleben, W.; Wright, G. D.; Ziemert, N.; Zhang, C.; Zotchev, S. B.; Breitling, R.; Takano, E.; Glockner, F. O. “Minimum Information about a Biosynthetic Gene cluster” Nat. Chem. Biol. 2015, 11, 625.
-
(2015)
Nat. Chem. Biol
, vol.11
, pp. 625
-
-
Medema, M.H.1
Kottmann, R.2
Yilmaz, P.3
Cummings, M.4
Biggins, J.B.5
Blin, K.6
de Bruijn, I.7
Chooi, Y.H.8
Claesen, J.9
Coates, R.C.10
Cruz-Morales, P.11
Duddela, S.12
Dusterhus, S.13
Edwards, D.J.14
Fewer, D.P.15
Garg, N.16
Geiger, C.17
Gomez- Escribano, J.P.18
Greule, A.19
Hadjithomas, M.20
Haines, A.S.21
Helfrich, E.J.N.22
Hillwig, M.L.23
Ishida, K.24
Jones, A.C.25
Jones, C.S.26
Jungmann, K.27
Kegler, C.28
Kim, H.U.29
Kotter, P.30
Krug, D.31
Masschelein, J.32
Melnik, A.V.33
Mantovani, S.M.34
Monroe, E.A.35
Moore, M.36
Moss, N.37
Nutzmann, H.-W.38
Pan, G.39
Pati, A.40
Petras, D.41
Reen, F.J.42
Rosconi, F.43
Rui, Z.44
Tian, Z.45
Tobias, N.J.46
Tsunematsu, Y.47
Wiemann, P.48
Wyckoff, E.49
Yan, X.50
Yim, G.51
Yu, F.52
Xie, Y.53
Aigle, B.54
Apel, A.K.55
Balibar, C.J.56
Balskus, E.P.57
Barona-Gomez, F.58
Bechthold, A.59
Bode, H.B.60
Borriss, R.61
Brady, S.F.62
Brakhage, A.A.63
Caffrey, P.64
Cheng, Y.-Q.65
Clardy, J.66
Cox, R.J.67
de Mot, R.68
Donadio, S.69
Donia, M.S.70
van der Donk, W.A.71
Dorrestein, P.C.72
Doyle, S.73
Driessen, A.J.M.74
Ehling-Schulz, M.75
Entian, K.-D.76
Fischbach, M.A.77
Gerwick, L.78
Gerwick, W.H.79
Gross, H.80
Gust, B.81
Hertweck, C.82
Hofte, M.83
Jensen, S.E.84
Ju, J.85
Katz, L.86
Kaysser, L.87
Klassen, J.L.88
Keller, N.P.89
Kormanec, J.90
Kuipers, O.P.91
Kuzuyama, T.92
Kyrpides, N.C.93
Kwon, H.-J.94
Lautru, S.95
Lavigne, R.96
Lee, C.Y.97
Linquan, B.98
Liu, X.99
Liu, W.100
Luzhetskyy, A.101
Mahmud, T.102
Mast, Y.103
Mendez, C.104
Metsa-Ketela, M.105
Micklefield, J.106
Mitchell, D.A.107
Moore, B.S.108
Moreira, L.M.109
Muller, R.110
Neilan, B.A.111
Nett, M.112
Nielsen, J.113
O'gara, F.114
Oikawa, H.115
Osbourn, A.116
Osburne, M.S.117
Ostash, B.118
Payne, S.M.119
Pernodet, J.-L.120
Petricek, M.121
Piel, J.122
Ploux, O.123
Raaijmakers, J.M.124
Salas, J.A.125
Schmitt, E.K.126
Scott, B.127
Seipke, R.F.128
Shen, B.129
Sherman, D.H.130
Sivonen, K.131
Smanski, M.J.132
Sosio, M.133
Stegmann, E.134
Sussmuth, R.D.135
Tahlan, K.136
Thomas, C.M.137
Tang, Y.138
Truman, A.W.139
Viaud, M.140
Walton, J.D.141
Walsh, C.T.142
Weber, T.143
Van Wezel, G.P.144
Wilkinson, B.145
Willey, J.M.146
Wohlleben, W.147
Wright, G.D.148
Ziemert, N.149
Zhang, C.150
Zotchev, S.B.151
Breitling, R.152
Takano, E.153
Glockner, F.O.154
more..
-
39
-
-
84904554933
-
Insights into secondary metabolism from a global analysis of prokaryotic biosynthetic gene clusters
-
Cimermancic, P.; Medema, M. H.; Claesen, J.; Kurita, K.; Brown, L. C. W.; Mavrommatis, K.; Pati, A.; Godfrey, P. A.; Koehrsen, M.; Clardy, J.; Birren, B. W.; Takano, E.; Sali, A.; Linington, R. G.; Fischbach, M. A. “Insights into secondary metabolism from a global analysis of prokaryotic biosynthetic gene clusters” Cell 2014, 158, 412.
-
(2014)
Cell
, vol.158
, pp. 412
-
-
Cimermancic, P.1
Medema, M.H.2
Claesen, J.3
Kurita, K.4
Brown, L.C.W.5
Mavrommatis, K.6
Pati, A.7
Godfrey, P.A.8
Koehrsen, M.9
Clardy, J.10
Birren, B.W.11
Takano, E.12
Sali, A.13
Linington, R.G.14
Fischbach, M.A.15
-
40
-
-
33748631825
-
Assembly-line enzymology for polyketide and nonribosomal peptide antibiotics: Logic, machinery, and mechanisms
-
Fischbach, M. A.; Walsh, C. T. “Assembly-line enzymology for polyketide and nonribosomal peptide antibiotics: logic, machinery, and mechanisms” Chem. Rev. 2006, 106, 3468.
-
(2006)
Chem. Rev
, vol.106
, pp. 3468
-
-
Fischbach, M.A.1
Walsh, C.T.2
-
41
-
-
69249202590
-
The biosynthetic logic of polyketide diversity
-
Hertweck, C. “The biosynthetic logic of polyketide diversity” Angew. Chem., Int. Ed. 2009, 48, 4688.
-
(2009)
Angew. Chem., Int. Ed
, vol.48
, pp. 4688
-
-
Hertweck, C.1
-
42
-
-
84875126202
-
Revealing nature’s synthetic potential through the study of ribosomal natural product biosynthesis
-
Dunbar, K. L.; Mitchell, D. A. “Revealing nature’s synthetic potential through the study of ribosomal natural product biosynthesis” ACS Chem. Biol. 2013, 8, 473.
-
(2013)
ACS Chem. Biol
, vol.8
, pp. 473
-
-
Dunbar, K.L.1
Mitchell, D.A.2
-
43
-
-
84870918230
-
Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature
-
Arnison, P. G.; Bibb, M. J.; Bierbaum, G.; Bowers, A. A.; Bugni, T. S.; Bulaj, G.; Camarero, J. A.; Campopiano, D. J.; Challis, G. L.; Clardy, J.; Cotter, P. D.; Craik, D. J.; Dawson, M.; Dittmann, E.; Donadio, S.; Dorrestein, P. C.; Entian, K. D.; Fischbach, M. A.; Garavelli, J. S.; Goransson, U.; Gruber, C. W.; Haft, D. H.; Hemscheidt, T. K.; Hertweck, C.; Hill, C.; Horswill, A. R.; Jaspars, M.; Kelly, W. L.; Klinman, J. P.; Kuipers, O. P.; Link, A. J.; Liu, W.; Marahiel, M. A.; Mitchell, D. A.; Moll, G. N.; Moore, B. S.; Muller, R.; Nair, S. K.; Nes, I. F.; Norris, G. E.; Olivera, B. M.; Onaka, H.; Patchett, M. L.; Piel, J.; Reaney, M. J.; Rebuffat, S.; Ross, R. P.; Sahl, H. G.; Schmidt, E. W.; Selsted, M. E.; Severinov, K.; Shen, B.; Sivonen, K.; Smith, L.; Stein, T.; Sussmuth, R. D.; Tagg, J. R.; Tang, G. L.; Truman, A. W.; Vederas, J. C.; Walsh, C. T.; Walton, J. D.; Wenzel, S. C.; Willey, J. M.; van der Donk, W. A. “Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature” Nat. Prod. Rep. 2013, 30, 108.
-
(2013)
Nat. Prod. Rep
, vol.30
, pp. 108
-
-
Arnison, P.G.1
Bibb, M.J.2
Bierbaum, G.3
Bowers, A.A.4
Bugni, T.S.5
Bulaj, G.6
Camarero, J.A.7
Campopiano, D.J.8
Challis, G.L.9
Clardy, J.10
Cotter, P.D.11
Craik, D.J.12
Dawson, M.13
Dittmann, E.14
Donadio, S.15
Dorrestein, P.C.16
Entian, K.D.17
Fischbach, M.A.18
Garavelli, J.S.19
Goransson, U.20
Gruber, C.W.21
Haft, D.H.22
Hemscheidt, T.K.23
Hertweck, C.24
Hill, C.25
Horswill, A.R.26
Jaspars, M.27
Kelly, W.L.28
Klinman, J.P.29
Kuipers, O.P.30
Link, A.J.31
Liu, W.32
Marahiel, M.A.33
Mitchell, D.A.34
Moll, G.N.35
Moore, B.S.36
Muller, R.37
Nair, S.K.38
Nes, I.F.39
Norris, G.E.40
Olivera, B.M.41
Onaka, H.42
Patchett, M.L.43
Piel, J.44
Reaney, M.J.45
Rebuffat, S.46
Ross, R.P.47
Sahl, H.G.48
Schmidt, E.W.49
Selsted, M.E.50
Severinov, K.51
Shen, B.52
Sivonen, K.53
Smith, L.54
Stein, T.55
Sussmuth, R.D.56
Tagg, J.R.57
Tang, G.L.58
Truman, A.W.59
Vederas, J.C.60
Walsh, C.T.61
Walton, J.D.62
Wenzel, S.C.63
Willey, J.M.64
van der Donk, W.A.65
more..
-
44
-
-
84865179264
-
Highthroughput bacterial genome sequencing: An embarrassment of choice, a world of opportunity
-
Loman, N. J.; Constantinidou, C.; Chan, J. Z.; Halachev, M.; Sergeant, M.; Penn, C. W.; Robinson, E. R.; Pallen, M. J. “Highthroughput bacterial genome sequencing: an embarrassment of choice, a world of opportunity” Nat. Rev. Microbiol. 2012, 10, 599.
-
(2012)
Nat. Rev. Microbiol
, vol.10
, pp. 599
-
-
Loman, N.J.1
Constantinidou, C.2
Chan, J.Z.3
Halachev, M.4
Sergeant, M.5
Penn, C.W.6
Robinson, E.R.7
Pallen, M.J.8
-
45
-
-
84857422020
-
-
Benson, D. A.; Karsch-Mizrachi, I.; Clark, K.; Lipman, D. J.; Ostell, J.; Sayers, E. W. “GenBank” Nucleic Acids Res. 2012, 40, D48.
-
(2012)
Wgenbanknucleic Acids Res
, vol.40
-
-
Benson, D.A.1
Karsch-Mizrachi, I.2
Clark, K.3
Lipman, D.J.4
Ostell, J.5
Sayers, E.6
-
46
-
-
78651317925
-
The European Nucleotide Archive
-
Leinonen, R.; Akhtar, R.; Birney, E.; Bower, L.; Cerdeno-Tarraga, A.; Cheng, Y.; Cleland, I.; Faruque, N.; Goodgame, N.; Gibson, R.; Hoad, G.; Jang, M.; Pakseresht, N.; Plaister, S.; Radhakrishnan, R.; Reddy, K.; Sobhany, S.; Ten Hoopen, P.; Vaughan, R.; Zalunin, V.; Cochrane, G. “The European Nucleotide Archive” Nucleic Acids Res. 2011, 39, D28.
-
(2011)
Nucleic Acids Res
, vol.39
-
-
Leinonen, R.1
Akhtar, R.2
Birney, E.3
Bower, L.4
Cerdeno-Tarraga, A.5
Cheng, Y.6
Cleland, I.7
Faruque, N.8
Goodgame, N.9
Gibson, R.10
Hoad, G.11
Jang, M.12
Pakseresht, N.13
Plaister, S.14
Radhakrishnan, R.15
Reddy, K.16
Sobhany, S.17
Ten Hoopen, P.18
Vaughan, R.19
Zalunin, V.20
Cochrane, G.21
more..
-
47
-
-
78651299550
-
Biological databases at DNA Data Bank of Japan in the era of next-generation sequencing technologies
-
Kodama, Y.; Kaminuma, E.; Saruhashi, S.; Ikeo, K.; Sugawara, H.; Tateno, Y.; Nakamura, Y. “Biological databases at DNA Data Bank of Japan in the era of next-generation sequencing technologies” Adv. Exp. Med. Biol. 2010, 680, 125.
-
(2010)
Adv. Exp. Med. Biol
, vol.680
, pp. 125
-
-
Kodama, Y.1
Kaminuma, E.2
Saruhashi, S.3
Ikeo, K.4
Sugawara, H.5
Tateno, Y.6
Nakamura, Y.7
-
48
-
-
0036081078
-
DNA Data Bank of Japan (DDBJ) for genome scale research in life science
-
Tateno, Y.; Imanishi, T.; Miyazaki, S.; Fukami-Kobayashi, K.; Saitou, N.; Sugawara, H.; Gojobori, T. “DNA Data Bank of Japan (DDBJ) for genome scale research in life science” Nucleic Acids Res. 2002, 30, 27.
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 27
-
-
Tateno, Y.1
Imanishi, T.2
Miyazaki, S.3
Fukami-Kobayashi, K.4
Saitou, N.5
Sugawara, H.6
Gojobori, T.7
-
49
-
-
84876573388
-
The International Nucleotide Sequence Database Collaboration
-
International Nucleotide Sequence Database, C
-
Nakamura, Y.; Cochrane, G.; Karsch-Mizrachi, I.; International Nucleotide Sequence Database, C. “The International Nucleotide Sequence Database Collaboration” Nucleic Acids Res. 2013, 41, D21.
-
(2013)
Nucleic Acids Res
, vol.41
-
-
Nakamura, Y.1
Cochrane, G.2
Karsch-Mizrachi, I.3
-
50
-
-
84891820094
-
IMG 4 version of the integrated microbial genomes comparative analysis system
-
Markowitz, V. M.; Chen, I. M.; Palaniappan, K.; Chu, K.; Szeto, E.; Pillay, M.; Ratner, A.; Huang, J.; Woyke, T.; Huntemann, M.; Anderson, I.; Billis, K.; Varghese, N.; Mavromatis, K.; Pati, A.; Ivanova, N. N.; Kyrpides, N. C. “IMG 4 version of the integrated microbial genomes comparative analysis system” Nucleic Acids Res. 2014, 42, D560.
-
(2014)
Nucleic Acids Res
, vol.42
-
-
Markowitz, V.M.1
Chen, I.M.2
Palaniappan, K.3
Chu, K.4
Szeto, E.5
Pillay, M.6
Ratner, A.7
Huang, J.8
Woyke, T.9
Huntemann, M.10
Anderson, I.11
Billis, K.12
Varghese, N.13
Mavromatis, K.14
Pati, A.15
Ivanova, N.N.16
Kyrpides, N.C.17
-
51
-
-
84891800783
-
IMG/M 4 version of the integrated metagenome comparative analysis system
-
Markowitz, V. M.; Chen, I. M.; Chu, K.; Szeto, E.; Palaniappan, K.; Pillay, M.; Ratner, A.; Huang, J.; Pagani, I.; Tringe, S.; Huntemann, M.; Billis, K.; Varghese, N.; Tennessen, K.; Mavromatis, K.; Pati, A.; Ivanova, N. N.; Kyrpides, N. C. “IMG/M 4 version of the integrated metagenome comparative analysis system” Nucleic Acids Res. 2014, 42, D568.
-
(2014)
Nucleic Acids Res
, vol.42
-
-
Markowitz, V.M.1
Chen, I.M.2
Chu, K.3
Szeto, E.4
Palaniappan, K.5
Pillay, M.6
Ratner, A.7
Huang, J.8
Pagani, I.9
Tringe, S.10
Huntemann, M.11
Billis, K.12
Varghese, N.13
Tennessen, K.14
Mavromatis, K.15
Pati, A.16
Ivanova, N.N.17
Kyrpides, N.C.18
-
52
-
-
27544456830
-
The impact of bacterial genomics on natural product research
-
Bode, H. B.; Muller, R. “The impact of bacterial genomics on natural product research” Angew. Chem., Int. Ed. 2005, 44, 6828.
-
(2005)
Angew. Chem., Int. Ed
, vol.44
, pp. 6828
-
-
Bode, H.B.1
Muller, R.2
-
53
-
-
84922466451
-
A roadmap for natural product discovery based on largescale genomics and metabolomics
-
Doroghazi, J. R.; Albright, J. C.; Goering, A. W.; Ju, K. S.; Haines, R. R.; Tchalukov, K. A.; Labeda, D. P.; Kelleher, N. L.; Metcalf, W. W. “A roadmap for natural product discovery based on largescale genomics and metabolomics” Nat. Chem. Biol. 2014, 10, 963.
-
(2014)
Nat. Chem. Biol
, vol.10
, pp. 963
-
-
Doroghazi, J.R.1
Albright, J.C.2
Goering, A.W.3
Ju, K.S.4
Haines, R.R.5
Tchalukov, K.A.6
Labeda, D.P.7
Kelleher, N.L.8
Metcalf, W.W.9
-
54
-
-
85028165246
-
Ten years of next-generation sequencing technology
-
van Dijk, E. L.; Auger, H.; Jaszczyszyn, Y.; Thermes, C. “Ten years of next-generation sequencing technology” Trends Genet. 2014, 30, 418.
-
(2014)
Trends Genet
, vol.30
, pp. 418
-
-
Van Dijk, E.L.1
Auger, H.2
Jaszczyszyn, Y.3
Thermes, C.4
-
55
-
-
84920693527
-
Next-generation sequencing approach for connecting secondary metabolites to biosynthetic gene clusters in fungi
-
Cacho, R. A.; Tang, Y.; Chooi, Y. H. “Next-generation sequencing approach for connecting secondary metabolites to biosynthetic gene clusters in fungi” Front. Microbiol. 2014, 5, 774.
-
(2014)
Front. Microbiol
, vol.5
, pp. 774
-
-
Cacho, R.A.1
Tang, Y.2
Chooi, Y.H.3
-
56
-
-
0037318402
-
A genomics-guided approach for discovering and expressing cryptic metabolic pathways
-
Zazopoulos, E.; Huang, K. X.; Staffa, A.; Liu, W.; Bachmann, B. O.; Nonaka, K.; Ahlert, J.; Thorson, J. S.; Shen, B.; Farnet, C. M. “A genomics-guided approach for discovering and expressing cryptic metabolic pathways” Nat. Biotechnol. 2003, 21, 187.
-
(2003)
Nat. Biotechnol
, vol.21
, pp. 187
-
-
Zazopoulos, E.1
Huang, K.X.2
Staffa, A.3
Liu, W.4
Bachmann, B.O.5
Nonaka, K.6
Ahlert, J.7
Thorson, J.S.8
Shen, B.9
Farnet, C.M.10
-
58
-
-
17844407663
-
Microbial genomics as a guide to drug discovery and structural elucidation: ECO- 02301, a novel antifungal agent, as an example
-
McAlpine, J. B.; Bachmann, B. O.; Piraee, M.; Tremblay, S.; Alarco, A. M.; Zazopoulos, E.; Farnet, C. M. “Microbial genomics as a guide to drug discovery and structural elucidation: ECO- 02301, a novel antifungal agent, as an example” J. Nat. Prod. 2005, 68, 493.
-
(2005)
J. Nat. Prod
, vol.68
, pp. 493
-
-
McAlpine, J.B.1
Bachmann, B.O.2
Piraee, M.3
Tremblay, S.4
Alarco, A.M.5
Zazopoulos, E.6
Farnet, C.M.7
-
59
-
-
33751254066
-
Genomic analyses lead to novel secondary metabolites. Part 3 ECO-0501, a novel antibacterial of a new class
-
Banskota, A. H.; McAlpine, J. B.; Sorensen, D.; Ibrahim, A.; Aouidate, M.; Piraee, M.; Alarco, A. M.; Farnet, C. M.; Zazopoulos, E. “Genomic analyses lead to novel secondary metabolites. Part 3 ECO-0501, a novel antibacterial of a new class” J. Antibiot. 2006, 59, 533.
-
(2006)
J. Antibiot
, vol.59
, pp. 533
-
-
Banskota, A.H.1
McAlpine, J.B.2
Sorensen, D.3
Ibrahim, A.4
Aouidate, M.5
Piraee, M.6
Alarco, A.M.7
Farnet, C.M.8
Zazopoulos, E.9
-
60
-
-
54149083585
-
Biosynthesis of diazepinomicin/ECO-4601, a micromonospora secondary metabolite with a novel ring system
-
McAlpine, J. B.; Banskota, A. H.; Charan, R. D.; Schlingmann, G.; Zazopoulos, E.; Piraee, M.; Janso, J.; Bernan, V. S.; Aouidate, M.; Farnet, C. M.; Feng, X. D.; Zhao, Z. Z.; Carter, G. T. “Biosynthesis of diazepinomicin/ECO-4601, a micromonospora secondary metabolite with a novel ring system” J. Nat. Prod. 2008, 71, 1585.
-
(2008)
J. Nat. Prod
, vol.71
, pp. 1585
-
-
McAlpine, J.B.1
Banskota, A.H.2
Charan, R.D.3
Schlingmann, G.4
Zazopoulos, E.5
Piraee, M.6
Janso, J.7
Bernan, V.S.8
Aouidate, M.9
Farnet, C.M.10
Feng, X.D.11
Zhao, Z.Z.12
Carter, G.T.13
-
61
-
-
84862192766
-
ChEMBL: A large-scale bioactivity database for drug discovery
-
Gaulton, A.; Bellis, L. J.; Bento, A. P.; Chambers, J.; Davies, M.; Hersey, A.; Light, Y.; McGlinchey, S.; Michalovich, D.; Al- Lazikani, B.; Overington, J. P. “ChEMBL: a large-scale bioactivity database for drug discovery” Nucleic Acids Res. 2012, 40, D1100.
-
(2012)
Nucleic Acids Res
, vol.40
-
-
Gaulton, A.1
Bellis, L.J.2
Bento, A.P.3
Chambers, J.4
Davies, M.5
Hersey, A.6
Light, Y.7
McGlinchey, S.8
Michalovich, D.9
Al- Lazikani, B.10
Overington, J.P.11
-
62
-
-
84891762026
-
The ChEMBL bioactivity database: An update
-
Bento, A. P.; Gaulton, A.; Hersey, A.; Bellis, L. J.; Chambers, J.; Davies, M.; Kruger, F. A.; Light, Y.; Mak, L.; McGlinchey, S.; Nowotka, M.; Papadatos, G.; Santos, R.; Overington, J. P. “The ChEMBL bioactivity database: an update” Nucleic Acids Res. 2014, 42, D1083.
-
(2014)
Nucleic Acids Res
, vol.42
-
-
Bento, A.P.1
Gaulton, A.2
Hersey, A.3
Bellis, L.J.4
Chambers, J.5
Davies, M.6
Kruger, F.A.7
Light, Y.8
Mak, L.9
McGlinchey, S.10
Nowotka, M.11
Papadatos, G.12
Santos, R.13
Overington, J.P.14
-
63
-
-
75549092202
-
Chemical Entities of Biological Interest: An update
-
de Matos, P.; Alcantara, R.; Dekker, A.; Ennis, M.; Hastings, J.; Haug, K.; Spiteri, I.; Turner, S.; Steinbeck, C. “Chemical Entities of Biological Interest: an update” Nucleic Acids Res. 2010, 38, D249.
-
(2010)
Nucleic Acids Res
, vol.38
-
-
de Matos, P.1
Alcantara, R.2
Dekker, A.3
Ennis, M.4
Hastings, J.5
Haug, K.6
Spiteri, I.7
Turner, S.8
Steinbeck, C.9
-
64
-
-
38549094609
-
NORINE: A database of nonribosomal peptides
-
Caboche, S.; Pupin, M.; Leclere, V.; Fontaine, A.; Jacques, P.; Kucherov, G. “NORINE: a database of nonribosomal peptides” Nucleic Acids Res. 2008, 36, D326.
-
(2008)
Nucleic Acids Res
, vol.36
-
-
Caboche, S.1
Pupin, M.2
Leclere, V.3
Fontaine, A.4
Jacques, P.5
Kucherov, G.6
-
65
-
-
77249117208
-
BACTIBASE second release: A database and tool platform for bacteriocin characterization
-
Hammami, R.; Zouhir, A.; Le Lay, C.; Ben Hamida, J.; Fliss, I. “BACTIBASE second release: a database and tool platform for bacteriocin characterization” BMC Microbiol. 2010, 10, 22.
-
(2010)
BMC Microbiol
, vol.10
, pp. 22
-
-
Hammami, R.1
Zouhir, A.2
Le Lay, C.3
Ben Hamida, J.4
Fliss, I.5
-
66
-
-
38349095584
-
BACTIBASE: A new web-accessible database for bacteriocin characterization
-
Hammami, R.; Zouhir, A.; Ben Hamida, J.; Fliss, I. “BACTIBASE: a new web-accessible database for bacteriocin characterization” BMC Microbiol. 2007, 7, 89.
-
(2007)
BMC Microbiol
, vol.7
, pp. 89
-
-
Hammami, R.1
Zouhir, A.2
Ben Hamida, J.3
Fliss, I.4
-
67
-
-
84866676209
-
ThioFinder: A web-based tool for the identification of thiopeptide gene clusters in DNA sequences
-
Li, J.; Qu, X.; He, X.; Duan, L.; Wu, G.; Bi, D.; Deng, Z.; Liu, W.; Ou, H. Y. “ThioFinder: a web-based tool for the identification of thiopeptide gene clusters in DNA sequences” PLoS One 2012, 7, e45878.
-
(2012)
Plos One
, vol.7
-
-
Li, J.1
Qu, X.2
He, X.3
Duan, L.4
Wu, G.5
Bi, D.6
Deng, Z.7
Liu, W.8
Ou, H.Y.9
-
68
-
-
84876543738
-
StreptomeDB: A resource for natural compounds isolated from Streptomyces species
-
Lucas, X.; Senger, C.; Erxleben, A.; Gruning, B. A.; Doring, K.; Mosch, J.; Flemming, S.; Gunther, S. “StreptomeDB: a resource for natural compounds isolated from Streptomyces species” Nucleic Acids Res. 2013, 41, D1130.
-
(2013)
Nucleic Acids Res
, vol.41
-
-
Lucas, X.1
Senger, C.2
Erxleben, A.3
Gruning, B.A.4
Doring, K.5
Mosch, J.6
Flemming, S.7
Gunther, S.8
-
69
-
-
84875470601
-
Development of a natural products database from the biodiversity of Brazil
-
Valli, M.; dos Santos, R. N.; Figueira, L. D.; Nakajima, C. H.; Castro-Gamboa, I.; Andricopulo, A. D.; Bolzani, V. S. “Development of a natural products database from the biodiversity of Brazil” J. Nat. Prod. 2013, 76, 439.
-
(2013)
J. Nat. Prod
, vol.76
, pp. 439
-
-
Valli, M.1
Dos Santos, R.N.2
Figueira, L.D.3
Nakajima, C.H.4
Castro-Gamboa, I.5
Andricopulo, A.D.6
Bolzani, V.S.7
-
70
-
-
84941137806
-
Super Natural II--a database of natural products
-
Banerjee, P.; Erehman, J.; Gohlke, B. O.; Wilhelm, T.; Preissner, R.; Dunkel, M. “Super Natural II--a database of natural products” Nucleic Acids Res. 2015, 43, D935.
-
(2015)
Nucleic Acids Res
, vol.43
-
-
Banerjee, P.1
Erehman, J.2
Gohlke, B.O.3
Wilhelm, T.4
Preissner, R.5
Dunkel, M.6
-
71
-
-
33644878571
-
SuperNatural: A searchable database of available natural compounds
-
Dunkel, M.; Fullbeck, M.; Neumann, S.; Preissner, R. “SuperNatural: a searchable database of available natural compounds” Nucleic Acids Res. 2006, 34, D678.
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Dunkel, M.1
Fullbeck, M.2
Neumann, S.3
Preissner, R.4
-
72
-
-
0033982936
-
KEGG: Kyoto encyclopedia of genes and genomes
-
Kanehisa, M.; Goto, S. “KEGG: kyoto encyclopedia of genes and genomes” Nucleic Acids Res. 2000, 28, 27.
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 27
-
-
Kanehisa, M.1
Goto, S.2
-
73
-
-
32444432587
-
METLIN: A metabolite mass spectral database
-
Smith, C. A.; O’Maille, G.; Want, E. J.; Qin, C.; Trauger, S. A.; Brandon, T. R.; Custodio, D. E.; Abagyan, R.; Siuzdak, G. “METLIN: a metabolite mass spectral database” Ther. Drug. Monit. 2005, 27, 747.
-
(2005)
Ther. Drug. Monit
, vol.27
, pp. 747
-
-
Smith, C.A.1
O’Maille, G.2
Want, E.J.3
Qin, C.4
Trauger, S.A.5
Brandon, T.R.6
Custodio, D.E.7
Abagyan, R.8
Siuzdak, G.9
-
74
-
-
84888095812
-
Glycogenomics as a mass spectrometry-guided genome-mining method for microbial glycosylated molecules
-
Kersten, R. D.; Ziemert, N.; Gonzalez, D. J.; Duggan, B. M.; Nizet, V.; Dorrestein, P. C.; Moore, B. S. “Glycogenomics as a mass spectrometry-guided genome-mining method for microbial glycosylated molecules” Proc. Natl. Acad. Sci. U.S.A. 2013, 110, E4407.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A
, vol.110
-
-
Kersten, R.D.1
Ziemert, N.2
Gonzalez, D.J.3
Duggan, B.M.4
Nizet, V.5
Dorrestein, P.C.6
Moore, B.S.7
-
75
-
-
84876566794
-
ClusterMine360: A database of microbial PKS/NRPS biosynthesis
-
Conway, K. R.; Boddy, C. N. “ClusterMine360: a database of microbial PKS/NRPS biosynthesis” Nucleic Acids Res. 2013, 41, D402.
-
(2013)
Nucleic Acids Res
, vol.41
-
-
Conway, K.R.1
Boddy, C.N.2
-
76
-
-
84876517188
-
DoBISCUIT: A database of secondary metabolite biosynthetic gene clusters
-
Ichikawa, N.; Sasagawa, M.; Yamamoto, M.; Komaki, H.; Yoshida, Y.; Yamazaki, S.; Fujita, N. “DoBISCUIT: a database of secondary metabolite biosynthetic gene clusters” Nucleic Acids Res. 2013, 41, D408.
-
(2013)
Nucleic Acids Res
, vol.41
-
-
Ichikawa, N.1
Sasagawa, M.2
Yamamoto, M.3
Komaki, H.4
Yoshida, Y.5
Yamazaki, S.6
Fujita, N.7
-
77
-
-
84863299498
-
Recombinatorial biosynthesis of polyketides
-
Starcevic, A.; Wolf, K.; Diminic, J.; Zucko, J.; Ruzic, I. T.; Long, P. F.; Hranueli, D.; Cullum, J. “Recombinatorial biosynthesis of polyketides” J. Ind. Microbiol. Biotechnol. 2012, 39, 503.
-
(2012)
J. Ind. Microbiol. Biotechnol
, vol.39
, pp. 503
-
-
Starcevic, A.1
Wolf, K.2
Diminic, J.3
Zucko, J.4
Ruzic, I.T.5
Long, P.F.6
Hranueli, D.7
Cullum, J.8
-
78
-
-
84883353135
-
AntiSMASH 2.0-a versatile platform for genome mining of secondary metabolite producers
-
Blin, K.; Medema, M. H.; Kazempour, D.; Fischbach, M. A.; Breitling, R.; Takano, E.; Weber, T. “antiSMASH 2.0-a versatile platform for genome mining of secondary metabolite producers” Nucleic Acids Res. 2013, 41, W204.
-
(2013)
Nucleic Acids Res
, vol.41
-
-
Blin, K.1
Medema, M.H.2
Kazempour, D.3
Fischbach, M.A.4
Breitling, R.5
Takano, E.6
Weber, T.7
-
79
-
-
79959920872
-
AntiSMASH: Rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences
-
Medema, M. H.; Blin, K.; Cimermancic, P.; de Jager, V.; Zakrzewski, P.; Fischbach, M. A.; Weber, T.; Takano, E.; Breitling, R. “antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences” Nucleic Acids Res. 2011, 39, W339.
-
(2011)
Nucleic Acids Res
, vol.39
-
-
Medema, M.H.1
Blin, K.2
Cimermancic, P.3
de Jager, V.4
Zakrzewski, P.5
Fischbach, M.A.6
Weber, T.7
Takano, E.8
Breitling, R.9
-
80
-
-
84979859096
-
AntiSMASH 3.0-a comprehensive resource for the genome mining of biosynthetic gene clusters
-
Weber, T.; Blin, K.; Duddela, S.; Krug, D.; Kim, H. U.; Bruccoleri, R.; Lee, S. Y.; Fischbach, M. A.; Muller, R.; Wohlleben, W.; Breitling, R.; Takano, E.; Medema, M. H. “antiSMASH 3.0-a comprehensive resource for the genome mining of biosynthetic gene clusters” Nucleic Acids Res. 2015.
-
(2015)
Nucleic Acids Res
-
-
Weber, T.1
Blin, K.2
Duddela, S.3
Krug, D.4
Kim, H.U.5
Bruccoleri, R.6
Lee, S.Y.7
Fischbach, M.A.8
Muller, R.9
Wohlleben, W.10
Breitling, R.11
Takano, E.12
Medema, M.H.13
-
81
-
-
79959792587
-
The Genomic Standards Consortium
-
Field, D.; Amaral-Zettler, L.; Cochrane, G.; Cole, J. R.; Dawyndt, P.; Garrity, G. M.; Gilbert, J.; Glockner, F. O.; Hirschman, L.; Karsch-Mizrachi, I.; Klenk, H. P.; Knight, R.; Kottmann, R.; Kyrpides, N.; Meyer, F.; San Gil, I.; Sansone, S. A.; Schriml, L. M.; Sterk, P.; Tatusova, T.; Ussery, D. W.; White, O.; Wooley, J. “The Genomic Standards Consortium” PLoS Biol. 2011, 9, e1001088.
-
(2011)
Plos Biol
, vol.9
-
-
Field, D.1
Amaral-Zettler, L.2
Cochrane, G.3
Cole, J.R.4
Dawyndt, P.5
Garrity, G.M.6
Gilbert, J.7
Glockner, F.O.8
Hirschman, L.9
Karsch-Mizrachi, I.10
Klenk, H.P.11
Knight, R.12
Kottmann, R.13
Kyrpides, N.14
Meyer, F.15
San Gil, I.16
Sansone, S.A.17
Schriml, L.M.18
Sterk, P.19
Tatusova, T.20
Ussery, D.W.21
White, O.22
Wooley, J.23
more..
-
82
-
-
84895076285
-
Bioinformatics tools for genome mining of polyketide and non-ribosomal peptides
-
Boddy, C. N. “Bioinformatics tools for genome mining of polyketide and non-ribosomal peptides” J. Ind. Microbiol. Biotechnol. 2014, 41, 443.
-
(2014)
J. Ind. Microbiol. Biotechnol
, vol.41
, pp. 443
-
-
Boddy, C.N.1
-
83
-
-
84899651850
-
In silico tools for the analysis of antibiotic biosynthetic pathways
-
Weber, T. “In silico tools for the analysis of antibiotic biosynthetic pathways” Int. J. Med. Microbiol. 2014, 304, 230.
-
(2014)
Int. J. Med. Microbiol
, vol.304
, pp. 230
-
-
Weber, T.1
-
85
-
-
84934442432
-
Bioinformatics approaches and software for detection of secondary metabolic gene clusters
-
Fedorova, N. D.; Moktali, V.; Medema, M. H. “Bioinformatics approaches and software for detection of secondary metabolic gene clusters” Methods Mol. Biol. 2012, 944, 23.
-
(2012)
Methods Mol. Biol
, vol.944
, pp. 23
-
-
Fedorova, N.D.1
Moktali, V.2
Medema, M.H.3
-
86
-
-
67650898253
-
Automated genome mining for natural products
-
Li, M. H. T.; Ung, P. M. U.; Zajkowski, J.; Garneau-Tsodikova, S.; Sherman, D. H. “Automated genome mining for natural products” BMC Bioinf. 2009, 10.
-
(2009)
BMC Bioinf
, pp. 10
-
-
Li, M.H.T.1
Ung, P.M.U.2
Zajkowski, J.3
Garneau-Tsodikova, S.4
Sherman, D.H.5
-
87
-
-
84859078407
-
The Natural Product Domain Seeker NaPDoS: A phylogeny based bioinformatic tool to classify secondary metabolite gene diversity
-
Ziemert, N.; Podell, S.; Penn, K.; Badger, J. H.; Allen, E.; Jensen, P. R. “The Natural Product Domain Seeker NaPDoS: a phylogeny based bioinformatic tool to classify secondary metabolite gene diversity” PLoS One 2012, 7.
-
(2012)
Plos One
, pp. 7
-
-
Ziemert, N.1
Podell, S.2
Penn, K.3
Badger, J.H.4
Allen, E.5
Jensen, P.R.6
-
88
-
-
84881233426
-
Echinomycin biosynthesis
-
Sato, M.; Nakazawa, T.; Tsunematsu, Y.; Hotta, K.; Watanabe, K. “Echinomycin biosynthesis” Curr. Opin. Chem. Biol. 2013, 17, 537.
-
(2013)
Curr. Opin. Chem. Biol
, vol.17
, pp. 537
-
-
Sato, M.1
Nakazawa, T.2
Tsunematsu, Y.3
Hotta, K.4
Watanabe, K.5
-
89
-
-
77955274600
-
SMURF: Genomic mapping of fungal secondary metabolite clusters
-
Khaldi, N.; Seifuddin, F. T.; Turner, G.; Haft, D.; Nierman, W. C.; Wolfe, K. H.; Fedorova, N. D. “SMURF: Genomic mapping of fungal secondary metabolite clusters” Fungal Genet. Biol. 2010, 47, 736.
-
(2010)
Fungal Genet. Biol
, vol.47
, pp. 736
-
-
Khaldi, N.1
Seifuddin, F.T.2
Turner, G.3
Haft, D.4
Nierman, W.C.5
Wolfe, K.H.6
Fedorova, N.D.7
-
90
-
-
57149112966
-
ClustScan: An integrated program package for the semi-automatic annotation of modular biosynthetic gene clusters and in silico prediction of novel chemical structures
-
Starcevic, A.; Zucko, J.; Simunkovic, J.; Long, P. F.; Cullum, J.; Hranueli, D. “ClustScan: an integrated program package for the semi-automatic annotation of modular biosynthetic gene clusters and in silico prediction of novel chemical structures” Nucleic Acids Res. 2008, 36, 6882.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 6882
-
-
Starcevic, A.1
Zucko, J.2
Simunkovic, J.3
Long, P.F.4
Cullum, J.5
Hranueli, D.6
-
91
-
-
61649111711
-
CLUSEAN: A computer-based framework for the automated analysis of bacterial secondary metabolite biosynthetic gene clusters
-
Weber, T.; Rausch, C.; Lopez, P.; Hoof, I.; Gaykova, V.; Huson, D. H.; Wohlleben, W. “CLUSEAN: a computer-based framework for the automated analysis of bacterial secondary metabolite biosynthetic gene clusters” Journal of Biotechnology 2009, 140, 13.
-
(2009)
Journal of Biotechnology
, vol.140
, pp. 13
-
-
Weber, T.1
Rausch, C.2
Lopez, P.3
Hoof, I.4
Gaykova, V.5
Huson, D.H.6
Wohlleben, W.7
-
92
-
-
84883572507
-
BAGEL3: Automated identification of genes encoding bacteriocins and (non-)bactericidal posttranslationally modified peptides
-
van Heel, A. J.; de Jong, A.; Montalban-Lopez, M.; Kok, J.; Kuipers, O. P. “BAGEL3: automated identification of genes encoding bacteriocins and (non-)bactericidal posttranslationally modified peptides” Nucleic Acids Res. 2013, 41, W448.
-
(2013)
Nucleic Acids Res
, vol.41
-
-
Van Heel, A.J.1
de Jong, A.2
Montalban-Lopez, M.3
Kok, J.4
Kuipers, O.P.5
-
93
-
-
77954305252
-
BAGEL2: Mining for bacteriocins in genomic data
-
de Jong, A.; van Heel, A. J.; Kok, J.; Kuipers, O. P. “BAGEL2: mining for bacteriocins in genomic data” Nucleic Acids Res. 2010, 38, W647.
-
(2010)
Nucleic Acids Res
, vol.38
-
-
de Jong, A.1
van Heel, A.J.2
Kok, J.3
Kuipers, O.P.4
-
94
-
-
33747827906
-
BAGEL: A web-based bacteriocin genome mining tool
-
de Jong, A.; van Hijum, S. A. F. T.; Bijlsma, J. J. E.; Kok, J.; Kuipers, O. P. “BAGEL: a web-based bacteriocin genome mining tool” Nucleic Acids Res. 2006, 34, W273.
-
(2006)
Nucleic Acids Res
, vol.34
-
-
de Jong, A.1
van Hijum, S.A.F.T.2
Bijlsma, J.J.E.3
Kok, J.4
Kuipers, O.P.5
-
95
-
-
84920263575
-
ESNaPD: A versatile, web-based bioinformatics platform for surveying and mining natural product biosynthetic diversity from metagenomes
-
Reddy, B. V. B.; Milshteyn, A.; Charlop-Powers, Z.; Brady, S. F. “eSNaPD: a versatile, web-based bioinformatics platform for surveying and mining natural product biosynthetic diversity from metagenomes” Chem. Biol. 2014, 21, 1023.
-
(2014)
Chem. Biol
, vol.21
, pp. 1023
-
-
Reddy, B.V.B.1
Milshteyn, A.2
Charlop-Powers, Z.3
Brady, S.F.4
-
96
-
-
64249084052
-
Methods for in silico prediction of microbial polyketide and nonribosomal peptide biosynthetic pathways from DNA sequence data
-
Bachmann, B. O.; Ravel, J. “Methods for in silico prediction of microbial polyketide and nonribosomal peptide biosynthetic pathways from DNA sequence data” Complex Enzymes in Microbial Natural Product Biosynthesis, Part A: Overview Articles and Peptides 2009, 458, 181.
-
(2009)
Complex Enzymes in Microbial Natural Product Biosynthesis, Part A: Overview Articles and Peptides
, vol.458
, pp. 181
-
-
Bachmann, B.O.1
Ravel, J.2
-
97
-
-
84876340080
-
Classification of the adenylation and acyl-transferase activity of NRPS and PKS systems using ensembles of substrate specific hidden Markov models
-
Khayatt, B. I.; Overmars, L.; Siezen, R. J.; Francke, C. “Classification of the adenylation and acyl-transferase activity of NRPS and PKS systems using ensembles of substrate specific hidden Markov models” PLoS One 2013, 8, e62136.
-
(2013)
Plos One
, vol.8
-
-
Khayatt, B.I.1
Overmars, L.2
Siezen, R.J.3
Francke, C.4
-
98
-
-
26944502019
-
Specificity prediction of adenylation domains in nonribosomal peptide synthetases (NRPS) using transductive support vector machines (TSVMs)
-
Rausch, C.; Weber, T.; Kohlbacher, O.; Wohlleben, W.; Huson, D. H. “Specificity prediction of adenylation domains in nonribosomal peptide synthetases (NRPS) using transductive support vector machines (TSVMs)” Nucleic Acids Res. 2005, 33, 5799.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 5799
-
-
Rausch, C.1
Weber, T.2
Kohlbacher, O.3
Wohlleben, W.4
Huson, D.H.5
-
99
-
-
79959936207
-
NRPSpredictor2-a web server for predicting NRPS adenylation domain specificity
-
Rottig, M.; Medema, M. H.; Blin, K.; Weber, T.; Rausch, C.; Kohlbacher, O. “NRPSpredictor2-a web server for predicting NRPS adenylation domain specificity” Nucleic Acids Res. 2011, 39, W362.
-
(2011)
Nucleic Acids Res
, vol.39
-
-
Rottig, M.1
Medema, M.H.2
Blin, K.3
Weber, T.4
Rausch, C.5
Kohlbacher, O.6
-
100
-
-
84893481062
-
Predicting substrate specificity of adenylation domains of nonribosomal peptide synthetases and other protein properties by latent semantic indexing
-
Baranasic, D.; Zucko, J.; Diminic, J.; Gacesa, R.; Long, P. F.; Cullum, J.; Hranueli, D.; Starcevic, A. “Predicting substrate specificity of adenylation domains of nonribosomal peptide synthetases and other protein properties by latent semantic indexing” J. Ind. Microbiol. Biotechnol. 2014, 41, 461.
-
(2014)
J. Ind. Microbiol. Biotechnol
, vol.41
, pp. 461
-
-
Baranasic, D.1
Zucko, J.2
Diminic, J.3
Gacesa, R.4
Long, P.F.5
Cullum, J.6
Hranueli, D.7
Starcevic, A.8
-
101
-
-
84856587901
-
NRPSsp: Non-ribosomal peptide synthase substrate predictor
-
Prieto, C.; Garcia-Estrada, C.; Lorenzana, D.; Martin, J. F. “NRPSsp: non-ribosomal peptide synthase substrate predictor” Bioinformatics 2012, 28, 426.
-
(2012)
Bioinformatics
, vol.28
, pp. 426
-
-
Prieto, C.1
Garcia-Estrada, C.2
Lorenzana, D.3
Martin, J.F.4
-
102
-
-
77954265333
-
SBSPKS: Structure based sequence analysis of polyketide synthases
-
Anand, S.; Prasad, M. V. R.; Yadav, G.; Kumar, N.; Shehara, J.; Ansari, M. Z.; Mohanty, D. “SBSPKS: structure based sequence analysis of polyketide synthases” Nucleic Acids Res. 2010, 38, W487.
-
(2010)
Nucleic Acids Res
, vol.38
-
-
Anand, S.1
Prasad, M.V.R.2
Yadav, G.3
Kumar, N.4
Shehara, J.5
Ansari, M.Z.6
Mohanty, D.7
-
103
-
-
0041620248
-
SEARCHPKS: A program for detection and analysis of polyketide synthase domains
-
Yadav, G.; Gokhale, R. S.; Mohanty, D. “SEARCHPKS: a program for detection and analysis of polyketide synthase domains” Nucleic Acids Res. 2003, 31, 3654.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 3654
-
-
Yadav, G.1
Gokhale, R.S.2
Mohanty, D.3
-
104
-
-
23144453475
-
SEARCHGTr: A program for analysis of glycosyltransferases involved in glycosylation of secondary metabolites
-
Kamra, P.; Gokhale, R. S.; Mohanty, D. “SEARCHGTr: a program for analysis of glycosyltransferases involved in glycosylation of secondary metabolites” Nucleic Acids Res. 2005, 33, W220.
-
(2005)
Nucleic Acids Res
, vol.33
-
-
Kamra, P.1
Gokhale, R.S.2
Mohanty, D.3
-
105
-
-
84859051266
-
PKSIIIexplorer: TSVM approach for predicting Type III polyketide synthase proteins
-
Vijayan, M.; Chandrika, S. K.; Vasudevan, S. E. “PKSIIIexplorer: TSVM approach for predicting Type III polyketide synthase proteins” Bioinformation 2011, 6, 125.
-
(2011)
Bioinformation
, vol.6
, pp. 125
-
-
Vijayan, M.1
Chandrika, S.K.2
Vasudevan, S.E.3
-
106
-
-
84864566650
-
PKMiner: A database for exploring type II polyketide synthases
-
Kim, J.; Yi, G. S. “PKMiner: a database for exploring type II polyketide synthases” BMC Microbiol. 2012, 12.
-
(2012)
BMC Microbiol
, pp. 12
-
-
Kim, J.1
Yi, G.S.2
-
107
-
-
84907584619
-
Pep2Path: Automated mass spectrometry-guided genome mining of peptidic natural productsPLoS Comput
-
Medema, M. H.; Paalvast, Y.; Nguyen, D. D.; Melnik, A.; Dorrestein, P. C.; Takano, E.; Breitling, R. “Pep2Path: automated mass spectrometry-guided genome mining of peptidic natural products” PLoS Comput. Biol. 2014, 10, e1003822.
-
(2014)
Biol
, vol.10
-
-
Medema, M.H.1
Paalvast, Y.2
Nguyen, D.D.3
Melnik, A.4
Dorrestein, P.C.5
Takano, E.6
Breitling, R.7
-
108
-
-
84904547209
-
Automated genome mining of ribosomal peptide natural products
-
Mohimani, H.; Kersten, R. D.; Liu, W. T.; Wang, M. X.; Purvine, S. O.; Wu, S.; Brewer, H. M.; Pasa-Tolic, L.; Bandeira, N.; Moore, B. S.; Pevzner, P. A.; Dorrestein, P. C. “Automated genome mining of ribosomal peptide natural products” ACS Chem. Biol. 2014, 9, 1545.
-
(2014)
ACS Chem. Biol
, vol.9
, pp. 1545
-
-
Mohimani, H.1
Kersten, R.D.2
Liu, W.T.3
Wang, M.X.4
Purvine, S.O.5
Wu, S.6
Brewer, H.M.7
Pasa-Tolic, L.8
Bandeira, N.9
Moore, B.S.10
Pevzner, P.A.11
Dorrestein, P.C.12
-
109
-
-
84906678559
-
NRPquest: Coupling mass spectrometry and genome mining for nonribosomal peptide discovery
-
Mohimani, H.; Liu, W. T.; Kersten, R. D.; Moore, B. S.; Dorrestein, P. C.; Pevzner, P. A. “NRPquest: coupling mass spectrometry and genome mining for nonribosomal peptide discovery” J. Nat. Prod. 2014, 77, 1902.
-
(2014)
J. Nat. Prod
, vol.77
, pp. 1902
-
-
Mohimani, H.1
Liu, W.T.2
Kersten, R.D.3
Moore, B.S.4
Dorrestein, P.C.5
Pevzner, P.A.6
-
110
-
-
84869792678
-
Dereplicating nonribosomal peptides using an informatic search algorithm for natural products (ISNAP) discovery
-
Ibrahim, A.; Yang, L.; Johnston, C.; Liu, X. W.; Ma, B.; Magarvey, N. A. “Dereplicating nonribosomal peptides using an informatic search algorithm for natural products (iSNAP) discovery” Proc. Natl. Acad. Sci. U.S.A. 2012, 109, 19196.
-
(2012)
Proc. Natl. Acad. Sci. U.S.A
, vol.109
, pp. 19196
-
-
Ibrahim, A.1
Yang, L.2
Johnston, C.3
Liu, X.W.4
Ma, B.5
Magarvey, N.A.6
-
111
-
-
84920866686
-
Automated identification of depsipeptide natural products by an informatic search algorithm
-
Skinnider, M. A.; Johnston, C. W.; Zvanych, R.; Magarvey, N. A. “Automated identification of depsipeptide natural products by an informatic search algorithm” ChemBioChem 2015, 16, 223.
-
(2015)
Chembiochem
, vol.16
, pp. 223
-
-
Skinnider, M.A.1
Johnston, C.W.2
Zvanych, R.3
Magarvey, N.A.4
-
112
-
-
0025183708
-
Basic Local Alignment Search Tool
-
Altschul, S. F.; Gish, W.; Miller, W.; Myers, E. W.; Lipman, D. J. “Basic Local Alignment Search Tool” J. Mol. Biol. 1990, 215, 403.
-
(1990)
J. Mol. Biol
, vol.215
, pp. 403
-
-
Altschul, S.F.1
Gish, W.2
Miller, W.3
Myers, E.W.4
Lipman, D.J.5
-
113
-
-
84876587454
-
Detecting sequence homology at the gene cluster level with MultiGeneBlast
-
Medema, M. H.; Takano, E.; Breitling, R. “Detecting sequence homology at the gene cluster level with MultiGeneBlast” Mol. Biol. Evol. 2013, 30, 1218.
-
(2013)
Mol. Biol. Evol
, vol.30
, pp. 1218
-
-
Medema, M.H.1
Takano, E.2
Breitling, R.3
-
114
-
-
0031743421
-
Profile hidden Markov models
-
Eddy, S. R. “Profile hidden Markov models” Bioinformatics 1998, 14, 755.
-
(1998)
Bioinformatics
, vol.14
, pp. 755
-
-
Eddy, S.R.1
-
115
-
-
77952988108
-
A new generation of homology search tools based on probabilistic inference
-
Eddy, S. R. “A new generation of homology search tools based on probabilistic inference” Genome Inform. 2009, 23, 205.
-
(2009)
Genome Inform
, vol.23
, pp. 205
-
-
Eddy, S.R.1
-
116
-
-
84941349095
-
HMMER web server: 2015 update
-
Finn, R. D.; Clements, J.; Arndt, W.; Miller, B. L.; Wheeler, T. J.; Schreiber, F.; Bateman, A.; Eddy, S. R. “HMMER web server: 2015 update” Nucleic Acids Res. 2015, 43, W30.
-
(2015)
Nucleic Acids Res
, vol.43
-
-
Finn, R.D.1
Clements, J.2
Arndt, W.3
Miller, B.L.4
Wheeler, T.J.5
Schreiber, F.6
Bateman, A.7
Eddy, S.R.8
-
117
-
-
79959931985
-
HMMER web server: Interactive sequence similarity searching
-
Finn, R. D.; Clements, J.; Eddy, S. R. “HMMER web server: interactive sequence similarity searching” Nucleic Acids Res. 2011, 39, W29.
-
(2011)
Nucleic Acids Res
, vol.39
-
-
Finn, R.D.1
Clements, J.2
Eddy, S.R.3
-
118
-
-
84864278347
-
Using sequence similarity networks for visualization of relationships across diverse protein superfamilies
-
Atkinson, H. J.; Morris, J. H.; Ferrin, T. E.; Babbitt, P. C. “Using sequence similarity networks for visualization of relationships across diverse protein superfamilies” PLoS One 2009, 4, e4345.
-
(2009)
Plos One
, vol.4
-
-
Atkinson, H.J.1
Morris, J.H.2
Ferrin, T.E.3
Babbitt, P.C.4
-
119
-
-
81255138862
-
The Enzyme Function Initiative
-
Gerlt, J. A.; Allen, K. N.; Almo, S. C.; Armstrong, R. N.; Babbitt, P. C.; Cronan, J. E.; Dunaway-Mariano, D.; Imker, H. J.; Jacobson, M. P.; Minor, W.; Poulter, C. D.; Raushel, F. M.; Sali, A.; Shoichet, B. K.; Sweedler, J. V. “The Enzyme Function Initiative” Biochemistry 2011, 50, 9950.
-
(2011)
Biochemistry
, vol.50
, pp. 9950
-
-
Gerlt, J.A.1
Allen, K.N.2
Almo, S.C.3
Armstrong, R.N.4
Babbitt, P.C.5
Cronan, J.E.6
Dunaway-Mariano, D.7
Imker, H.J.8
Jacobson, M.P.9
Minor, W.10
Poulter, C.D.11
Raushel, F.M.12
Sali, A.13
Shoichet, B.K.14
Sweedler, J.V.15
-
120
-
-
84929376894
-
Enzyme Function Initiative- Enzyme Similarity Tool (EFI-EST): A web tool for generating protein sequence similarity networks
-
Gerlt, J. A.; Bouvier, J. T.; Davidson, D. B.; Imker, H. J.; Sadkhin, B.; Slater, D. R.; Whalen, K. L. “Enzyme Function Initiative- Enzyme Similarity Tool (EFI-EST): a web tool for generating protein sequence similarity networks” Biochim. Biophys. Acta 2015, 1854, 1019.
-
(2015)
Biochim. Biophys. Acta
, vol.1854
, pp. 1019
-
-
Gerlt, J.A.1
Bouvier, J.T.2
Davidson, D.B.3
Imker, H.J.4
Sadkhin, B.5
Slater, D.R.6
Whalen, K.L.7
-
121
-
-
0242490780
-
Cytoscape: A software environment for integrated models of biomolecular interaction networks
-
Shannon, P.; Markiel, A.; Ozier, O.; Baliga, N. S.; Wang, J. T.; Ramage, D.; Amin, N.; Schwikowski, B.; Ideker, T. “Cytoscape: a software environment for integrated models of biomolecular interaction networks” Genome Res. 2003, 13, 2498.
-
(2003)
Genome Res
, vol.13
, pp. 2498
-
-
Shannon, P.1
Markiel, A.2
Ozier, O.3
Baliga, N.S.4
Wang, J.T.5
Ramage, D.6
Amin, N.7
Schwikowski, B.8
Ideker, T.9
-
122
-
-
79952202448
-
Cytoscape: Software for visualization and analysis of biological networks
-
Kohl, M.; Wiese, S.; Warscheid, B. “Cytoscape: software for visualization and analysis of biological networks” Methods Mol. Biol. 2011, 696, 291.
-
(2011)
Methods Mol. Biol
, vol.696
, pp. 291
-
-
Kohl, M.1
Wiese, S.2
Warscheid, B.3
-
123
-
-
84904306550
-
Interactive XCMS Online: Simplifying advanced metabolomic data processing and subsequent statistical analyses
-
Gowda, H.; Ivanisevic, J.; Johnson, C. H.; Kurczy, M. E.; Benton, H. P.; Rinehart, D.; Nguyen, T.; Ray, J.; Kuehl, J.; Arevalo, B.; Westenskow, P. D.; Wang, J.; Arkin, A. P.; Deutschbauer, A. M.; Patti, G. J.; Siuzdak, G. “Interactive XCMS Online: simplifying advanced metabolomic data processing and subsequent statistical analyses” Anal. Chem. 2014, 86, 6931.
-
(2014)
Anal. Chem
, vol.86
, pp. 6931
-
-
Gowda, H.1
Ivanisevic, J.2
Johnson, C.H.3
Kurczy, M.E.4
Benton, H.P.5
Rinehart, D.6
Nguyen, T.7
Ray, J.8
Kuehl, J.9
Arevalo, B.10
Westenskow, P.D.11
Wang, J.12
Arkin, A.P.13
Deutschbauer, A.M.14
Patti, G.J.15
Siuzdak, G.16
-
124
-
-
84861915827
-
XCMS Online: A web-based platform to process untargeted metabolomic data
-
Tautenhahn, R.; Patti, G. J.; Rinehart, D.; Siuzdak, G. “XCMS Online: a web-based platform to process untargeted metabolomic data” Anal. Chem. 2012, 84, 5035.
-
(2012)
Anal. Chem
, vol.84
, pp. 5035
-
-
Tautenhahn, R.1
Patti, G.J.2
Rinehart, D.3
Siuzdak, G.4
-
125
-
-
84934434481
-
Correlating secondary metabolite production with genetic changes using differential analysis of 2D NMR spectra
-
Forseth, R. R.; Schroeder, F. C. “Correlating secondary metabolite production with genetic changes using differential analysis of 2D NMR spectra” Methods Mol. Biol. 2012, 944, 207.
-
(2012)
Methods Mol. Biol
, vol.944
, pp. 207
-
-
Forseth, R.R.1
Schroeder, F.C.2
-
126
-
-
0034659816
-
Coelichelin, a new peptide siderophore encoded by the Streptomyces coelicolor genome: Structure prediction from the sequence of its non-ribosomal peptide synthetase
-
Challis, G. L.; Ravel, J. “Coelichelin, a new peptide siderophore encoded by the Streptomyces coelicolor genome: structure prediction from the sequence of its non-ribosomal peptide synthetase” FEMS Microbiol. Lett. 2000, 187, 111.
-
(2000)
FEMS Microbiol. Lett
, vol.187
, pp. 111
-
-
Challis, G.L.1
Ravel, J.2
-
127
-
-
0028826917
-
Bacillaene, a novel inhibitor of prodaryotic protein synthesis produced by Bacillus subtilis: Production, taxonomy, isolation, physico-chemical characterization and biological activity
-
Patel, P. S.; Huang, S.; Fisher, S.; Pirnik, D.; Aklonis, C.; Dean, L.; Meyers, E.; Fernandes, P.; Mayerl, F. “Bacillaene, a novel inhibitor of prodaryotic protein synthesis produced by Bacillus subtilis: production, taxonomy, isolation, physico-chemical characterization and biological activity” J. Antibiot. 1995, 48, 997.
-
(1995)
J. Antibiot
, vol.48
, pp. 997
-
-
Patel, P.S.1
Huang, S.2
Fisher, S.3
Pirnik, D.4
Aklonis, C.5
Dean, L.6
Meyers, E.7
Fernandes, P.8
Mayerl, F.9
-
128
-
-
76649090949
-
The final steps of bacillaene biosynthesis in Bacillus amyloliquefaciens FZB42: Direct evidence for β,γ dehydration by a trans-acyltransferase polyketide synthase
-
Moldenhauer, J.; Gotz, D. C.; Albert, C. R.; Bischof, S. K.; Schneider, K.; Sussmuth, R. D.; Engeser, M.; Gross, H.; Bringmann, G.; Piel, J. “The final steps of bacillaene biosynthesis in Bacillus amyloliquefaciens FZB42: direct evidence for β,γ dehydration by a trans-acyltransferase polyketide synthase” Angew. Chem., Int. Ed. 2010, 49, 1465.
-
(2010)
Angew. Chem., Int. Ed
, vol.49
, pp. 1465
-
-
Moldenhauer, J.1
Gotz, D.C.2
Albert, C.R.3
Bischof, S.K.4
Schneider, K.5
Sussmuth, R.D.6
Engeser, M.7
Gross, H.8
Bringmann, G.9
Piel, J.10
-
129
-
-
33846807734
-
The identification of bacillaene, the product of the PksX megacomplex in Bacillus subtilis
-
Butcher, R. A.; Schroeder, F. C.; Fischbach, M. A.; Straightt, P. D.; Kolter, R.; Walsh, C. T.; Clardy, J. “The identification of bacillaene, the product of the PksX megacomplex in Bacillus subtilis” Proc. Natl. Acad. Sci. U.S.A. 2007, 104, 1506.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A
, vol.104
, pp. 1506
-
-
Butcher, R.A.1
Schroeder, F.C.2
Fischbach, M.A.3
Straightt, P.D.4
Kolter, R.5
Walsh, C.T.6
Clardy, J.7
-
130
-
-
33744775994
-
Structural and functional characterization of three polyketide synthase gene clusters in Bacillus amyloliquefaciens FZB 42
-
Chen, X. H.; Vater, J.; Piel, J.; Franke, P.; Scholz, R.; Schneider, K.; Koumoutsi, A.; Hitzeroth, G.; Grammel, N.; Strittmatter, A. W.; Gottschalk, G.; Sussmuth, R. D.; Borriss, R. “Structural and functional characterization of three polyketide synthase gene clusters in Bacillus amyloliquefaciens FZB 42” J. Bacteriol. 2006, 188, 4024.
-
(2006)
J. Bacteriol
, vol.188
, pp. 4024
-
-
Chen, X.H.1
Vater, J.2
Piel, J.3
Franke, P.4
Scholz, R.5
Schneider, K.6
Koumoutsi, A.7
Hitzeroth, G.8
Grammel, N.9
Strittmatter, A.W.10
Gottschalk, G.11
Sussmuth, R.D.12
Borriss, R.13
-
131
-
-
33846115614
-
A singular enzymatic megacomplex from Bacillus subtilis
-
Straight, P. D.; Fischbach, M. A.; Walsh, C. T.; Rudner, D. Z.; Kolter, R. “A singular enzymatic megacomplex from Bacillus subtilis” Proc. Natl. Acad. Sci. U.S.A. 2007, 104, 305.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A
, vol.104
, pp. 305
-
-
Straight, P.D.1
Fischbach, M.A.2
Walsh, C.T.3
Rudner, D.Z.4
Kolter, R.5
-
132
-
-
36048989307
-
Biosynthesis of the antibiotic bacillaene, the product of a giant polyketide synthase complex of the trans-AT family
-
Moldenhauer, J.; Chen, X. H.; Borriss, R.; Piel, J. “Biosynthesis of the antibiotic bacillaene, the product of a giant polyketide synthase complex of the trans-AT family” Angew. Chem., Int. Ed. 2007, 46, 8195.
-
(2007)
Angew. Chem., Int. Ed
, vol.46
, pp. 8195
-
-
Moldenhauer, J.1
Chen, X.H.2
Borriss, R.3
Piel, J.4
-
133
-
-
0037452723
-
PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin
-
Gust, B.; Challis, G. L.; Fowler, K.; Kieser, T.; Chater, K. F. “PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin” Proc. Natl. Acad. Sci. U.S.A. 2003, 100, 1541.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A
, vol.100
, pp. 1541
-
-
Gust, B.1
Challis, G.L.2
Fowler, K.3
Kieser, T.4
Chater, K.F.5
-
134
-
-
33845212858
-
Type III polyketide synthase beta-ketoacyl-ACP starter unit and ethylmalonyl-CoA extender unit selectivity discovered by Streptomyces coelicolor genome mining
-
Song, L. J.; Barona-Gomez, F.; Corre, C.; Xiang, L. K.; Udwary, D. W.; Austin, M. B.; Noel, J. P.; Moore, B. S.; Challis, G. L. “Type III polyketide synthase beta-ketoacyl-ACP starter unit and ethylmalonyl-CoA extender unit selectivity discovered by Streptomyces coelicolor genome mining” J. Am. Chem. Soc. 2006, 128, 14754.
-
(2006)
J. Am. Chem. Soc
, vol.128
, pp. 14754
-
-
Song, L.J.1
Barona-Gomez, F.2
Corre, C.3
Xiang, L.K.4
Udwary, D.W.5
Austin, M.B.6
Noel, J.P.7
Moore, B.S.8
Challis, G.L.9
-
135
-
-
79960359850
-
A genome-wide polyketide synthase deletion library uncovers novel genetic links to polyketides and meroterpenoids in Aspergillus nidulansFEMS Microbiol
-
Nielsen, M. L.; Nielsen, J. B.; Rank, C.; Klejnstrup, M. L.; Holm, D. K.; Brogaard, K. H.; Hansen, B. G.; Frisvad, J. C.; Larsen, T. O.; Mortensen, U. H. “A genome-wide polyketide synthase deletion library uncovers novel genetic links to polyketides and meroterpenoids in Aspergillus nidulans” FEMS Microbiol. Lett. 2011, 321, 157.
-
(2011)
Lett
, vol.321
, pp. 157
-
-
Nielsen, M.L.1
Nielsen, J.B.2
Rank, C.3
Klejnstrup, M.L.4
Holm, D.K.5
Brogaard, K.H.6
Hansen, B.G.7
Frisvad, J.C.8
Larsen, T.O.9
Mortensen, U.H.10
-
136
-
-
78650083538
-
Plantazolicin, a novel microcin B17/streptolysin S-like natural product from Bacillus amyloliquefaciens FZB42
-
Scholz, R.; Molohon, K. J.; Nachtigall, J.; Vater, J.; Markley, A. L.; Sussmuth, R. D.; Mitchell, D. A.; Borriss, R. “Plantazolicin, a novel microcin B17/streptolysin S-like natural product from Bacillus amyloliquefaciens FZB42” J. Bacteriol. 2011, 193, 215.
-
(2011)
J. Bacteriol
, vol.193
, pp. 215
-
-
Scholz, R.1
Molohon, K.J.2
Nachtigall, J.3
Vater, J.4
Markley, A.L.5
Sussmuth, R.D.6
Mitchell, D.A.7
Borriss, R.8
-
137
-
-
84889662208
-
Structure and biosynthesis of xenoamicins from entomopathogenic Xenorhabdus
-
Zhou, Q. Q.; Grundmann, F.; Kaiser, M.; Schiell, M.; Gaudriault, S.; Batzer, A.; Kurz, M.; Bode, H. B. “Structure and biosynthesis of xenoamicins from entomopathogenic Xenorhabdus” Chem. Eur. J. 2013, 19, 16772.
-
(2013)
Chem. Eur. J
, vol.19
, pp. 16772
-
-
Zhou, Q.Q.1
Grundmann, F.2
Kaiser, M.3
Schiell, M.4
Gaudriault, S.5
Batzer, A.6
Kurz, M.7
Bode, H.B.8
-
138
-
-
30744456748
-
Genomic mining for Aspergillus natural products
-
Bok, J. W.; Hoffmeister, D.; Maggio-Hall, L. A.; Murillo, R.; Glasner, J. D.; Keller, N. P. “Genomic mining for Aspergillus natural products” Chem. Biol. 2006, 13, 31.
-
(2006)
Chem. Biol
, vol.13
, pp. 31
-
-
Bok, J.W.1
Hoffmeister, D.2
Maggio-Hall, L.A.3
Murillo, R.4
Glasner, J.D.5
Keller, N.P.6
-
139
-
-
45149124021
-
Molecular genetic mining of the Aspergillus secondary metabolome: Discovery of the emericellamide biosynthetic pathway
-
Chiang, Y. M.; Szewczyk, E.; Nayak, T.; Davidson, A. D.; Sanchez, J. F.; Lo, H. C.; Ho, W. Y.; Simityan, H.; Kuo, E.; Praseuth, A.; Watanabe, K.; Oakley, B. R.; Wang, C. C. C. “Molecular genetic mining of the Aspergillus secondary metabolome: discovery of the emericellamide biosynthetic pathway” Chem. Biol. 2008, 15, 527.
-
(2008)
Chem. Biol
, vol.15
, pp. 527
-
-
Chiang, Y.M.1
Szewczyk, E.2
Nayak, T.3
Davidson, A.D.4
Sanchez, J.F.5
Lo, H.C.6
Ho, W.Y.7
Simityan, H.8
Kuo, E.9
Praseuth, A.10
Watanabe, K.11
Oakley, B.R.12
Wang, C.13
-
140
-
-
84868515764
-
Genomics-driven discovery of burkholderic acid, a noncanonical, cryptic polyketide from human pathogenic Burkholderia species
-
Franke, J.; Ishida, K.; Hertweck, C. “Genomics-driven discovery of burkholderic acid, a noncanonical, cryptic polyketide from human pathogenic Burkholderia species” Angew. Chem., Int. Ed. 2012, 51, 11611.
-
(2012)
Angew. Chem., Int. Ed
, vol.51
, pp. 11611
-
-
Franke, J.1
Ishida, K.2
Hertweck, C.3
-
141
-
-
84865138150
-
Malleilactone, a polyketide synthase-derived virulence factor encoded by the cryptic secondary metabolome of Burkholderia pseudomallei group pathogens
-
Biggins, J. B.; Ternei, M. A.; Brady, S. F. “Malleilactone, a polyketide synthase-derived virulence factor encoded by the cryptic secondary metabolome of Burkholderia pseudomallei group pathogens” J. Am. Chem. Soc. 2012, 134, 13192.
-
(2012)
J. Am. Chem. Soc
, vol.134
, pp. 13192
-
-
Biggins, J.B.1
Ternei, M.A.2
Brady, S.F.3
-
142
-
-
79952593656
-
Acyldepsipeptide HDAC inhibitor production induced in Burkholderia thailandensis
-
Biggins, J. B.; Gleber, C. D.; Brady, S. F. “Acyldepsipeptide HDAC inhibitor production induced in Burkholderia thailandensis” Org. Lett. 2011, 13, 1536.
-
(2011)
Org. Lett
, vol.13
, pp. 1536
-
-
Biggins, J.B.1
Gleber, C.D.2
Brady, S.F.3
-
143
-
-
80055098514
-
Thailandepsins: Bacterial products with potent histone deacetylase inhibitory activities and broad-spectrum antiproliferative activities
-
Wang, C.; Henkes, L. M.; Doughty, L. B.; He, M.; Wang, D. F.; Meyer-Almes, F. J.; Cheng, Y. Q. “Thailandepsins: bacterial products with potent histone deacetylase inhibitory activities and broad-spectrum antiproliferative activities” J. Nat. Prod. 2011, 74, 2031.
-
(2011)
J. Nat. Prod
, vol.74
, pp. 2031
-
-
Wang, C.1
Henkes, L.M.2
Doughty, L.B.3
He, M.4
Wang, D.F.5
Meyer-Almes, F.J.6
Cheng, Y.Q.7
-
144
-
-
84873943666
-
Genome mining of a prenylated and immunosuppressive polyketide from pathogenic fungi
-
Chooi, Y. H.; Fang, J. X.; Liu, H.; Filler, S. G.; Wang, P.; Tang, Y. “Genome mining of a prenylated and immunosuppressive polyketide from pathogenic fungi” Org. Lett. 2013, 15, 780.
-
(2013)
Org. Lett
, vol.15
, pp. 780
-
-
Chooi, Y.H.1
Fang, J.X.2
Liu, H.3
Filler, S.G.4
Wang, P.5
Tang, Y.6
-
145
-
-
79954997859
-
Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens
-
Laureti, L.; Song, L. J.; Huang, S.; Corre, C.; Leblond, P.; Challis, G. L.; Aigle, B. “Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens” Proc. Natl. Acad. Sci. U.S.A. 2011, 108, 6258.
-
(2011)
Proc. Natl. Acad. Sci. U.S.A
, vol.108
, pp. 6258
-
-
Laureti, L.1
Song, L.J.2
Huang, S.3
Corre, C.4
Leblond, P.5
Challis, G.L.6
Aigle, B.7
-
146
-
-
84855805908
-
Myxoprincomide: A natural product from Myxococcus xanthus discovered by comprehensive analysis of the secondary metabolome
-
Cortina, N. S.; Krug, D.; Plaza, A.; Revermann, O.; Muller, R. “Myxoprincomide: a natural product from Myxococcus xanthus discovered by comprehensive analysis of the secondary metabolome” Angew. Chem., Int. Ed. 2012, 51, 811.
-
(2012)
Angew. Chem., Int. Ed
, vol.51
, pp. 811
-
-
Cortina, N.S.1
Krug, D.2
Plaza, A.3
Revermann, O.4
Muller, R.5
-
147
-
-
68049088909
-
A gene cluster containing two fungal polyketide synthases encodes the biosynthetic pathway for a polyketide, asperfuranone, in Aspergillus nidulans
-
Chiang, Y. M.; Szewczyk, E.; Davidson, A. D.; Keller, N.; Oakley, B. R.; Wang, C. C. C. “A gene cluster containing two fungal polyketide synthases encodes the biosynthetic pathway for a polyketide, asperfuranone, in Aspergillus nidulans” J. Am. Chem. Soc. 2009, 131, 2965.
-
(2009)
J. Am. Chem. Soc
, vol.131
-
-
Chiang, Y.M.1
Szewczyk, E.2
Davidson, A.D.3
Keller, N.4
Oakley, B.R.5
Wang, C.6
-
148
-
-
79953043201
-
Biosynthesis of the siderophore rhodochelin requires the coordinated expression of three independent gene clusters in Rhodococcus jostii RHA1
-
Bosello, M.; Robbel, L.; Linne, U.; Xie, X. L.; Marahiel, M. A. “Biosynthesis of the siderophore rhodochelin requires the coordinated expression of three independent gene clusters in Rhodococcus jostii RHA1” J. Am. Chem. Soc. 2011, 133, 4587.
-
(2011)
J. Am. Chem. Soc
, vol.133
, pp. 4587
-
-
Bosello, M.1
Robbel, L.2
Linne, U.3
Xie, X.L.4
Marahiel, M.A.5
-
149
-
-
84923368746
-
Natural combinatorial biosynthesis involving two clusters for the synthesis of three pyrrolamides in Streptomyces netropsis
-
Vingadassalon, A.; Lorieux, F.; Juguet, M.; Le Goff, G.; Gerbaud, C.; Pernodet, J. L.; Lautru, S. “Natural combinatorial biosynthesis involving two clusters for the synthesis of three pyrrolamides in Streptomyces netropsis” ACS Chem. Biol. 2015, 10, 601.
-
(2015)
ACS Chem. Biol
, vol.10
, pp. 601
-
-
Vingadassalon, A.1
Lorieux, F.2
Juguet, M.3
Le Goff, G.4
Gerbaud, C.5
Pernodet, J.L.6
Lautru, S.7
-
150
-
-
77952511174
-
Expansion of ribosomally produced natural products: A nitrile hydratase- and Nif11-related precursor family
-
Haft, D. H.; Basu, M. K.; Mitchell, D. A. “Expansion of ribosomally produced natural products: a nitrile hydratase- and Nif11-related precursor family” BMC Biol 2010, 8, 70.
-
(2010)
BMC Biol
, vol.8
, pp. 70
-
-
Haft, D.H.1
Basu, M.K.2
Mitchell, D.A.3
-
151
-
-
84893170608
-
Recent advances in the heterologous expression of microbial natural product biosynthetic pathways
-
Ongley, S. E.; Bian, X. Y.; Neilan, B. A.; Muller, R. “Recent advances in the heterologous expression of microbial natural product biosynthetic pathways” Nat. Prod. Rep. 2013, 30, 1121.
-
(2013)
Nat. Prod. Rep
, vol.30
, pp. 1121
-
-
Ongley, S.E.1
Bian, X.Y.2
Neilan, B.A.3
Muller, R.4
-
152
-
-
84908338451
-
Recent advances in natural product discovery
-
Luo, Y. Z.; Cobb, R. E.; Zhao, H. M. “Recent advances in natural product discovery” Curr. Opin. Biotechnol. 2014, 30, 230.
-
(2014)
Curr. Opin. Biotechnol
, vol.30
, pp. 230
-
-
Luo, Y.Z.1
Cobb, R.E.2
Zhao, H.M.3
-
153
-
-
84859450266
-
Lantibiotics from Geobacillus thermodenitrificans
-
Garg, N.; Tang, W. X.; Goto, Y.; Nair, S. K.; van der Donk, W. A. “Lantibiotics from Geobacillus thermodenitrificans” Proc. Natl. Acad. Sci. U.S.A. 2012, 109, 5241.
-
(2012)
Proc. Natl. Acad. Sci. U.S.A
, vol.109
, pp. 5241
-
-
Garg, N.1
Tang, W.X.2
Goto, Y.3
Nair, S.K.4
van der Donk, W.A.5
-
154
-
-
84866996786
-
Luminmycins AC, cryptic natural products from Photorhabdus luminescens identified by heterologous expression in Escherichia coli
-
Bian, X. Y.; Plaza, A.; Zhang, Y. M.; Muller, R. “Luminmycins AC, cryptic natural products from Photorhabdus luminescens identified by heterologous expression in Escherichia coli” J. Nat. Prod. 2012, 75, 1652.
-
(2012)
J. Nat. Prod
, vol.75
, pp. 1652
-
-
Bian, X.Y.1
Plaza, A.2
Zhang, Y.M.3
Muller, R.4
-
155
-
-
84860778298
-
Full-length RecE enhances linear-linear homologous recombination and facilitates direct cloning for bioprospecting
-
Fu, J.; Bian, X. Y.; Hu, S. B.; Wang, H. L.; Huang, F.; Seibert, P. M.; Plaza, A.; Xia, L. Q.; Muller, R.; Stewart, A. F.; Zhang, Y. M. “Full-length RecE enhances linear-linear homologous recombination and facilitates direct cloning for bioprospecting” Nat. Biotechnol. 2012, 30, 440.
-
(2012)
Nat. Biotechnol
, vol.30
, pp. 440
-
-
Fu, J.1
Bian, X.Y.2
Hu, S.B.3
Wang, H.L.4
Huang, F.5
Seibert, P.M.6
Plaza, A.7
Xia, L.Q.8
Muller, R.9
Stewart, A.F.10
Zhang, Y.M.11
-
156
-
-
84873727524
-
Discovery of indolotryptoline antiproliferative agents by homology-guided metagenomic screening
-
Chang, F. Y.; Brady, S. F. “Discovery of indolotryptoline antiproliferative agents by homology-guided metagenomic screening” Proc. Natl. Acad. Sci. U.S.A. 2013, 110, 2478.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A
, vol.110
, pp. 2478
-
-
Chang, F.Y.1
Brady, S.F.2
-
157
-
-
84889261817
-
Discovery and synthetic refactoring of tryptophan dimer gene clusters from the environment
-
Chang, F. Y.; Ternei, M. A.; Calle, P. Y.; Brady, S. F. “Discovery and synthetic refactoring of tryptophan dimer gene clusters from the environment” J. Am. Chem. Soc. 2013, 135, 17906.
-
(2013)
J. Am. Chem. Soc
, vol.135
, pp. 17906
-
-
Chang, F.Y.1
Ternei, M.A.2
Calle, P.Y.3
Brady, S.F.4
-
158
-
-
84885467685
-
Arimetamycin A: Improving clinically relevant families of natural products through sequence-guided screening of soil metagenomes
-
Kang, H. S.; Brady, S. F. “Arimetamycin A: Improving clinically relevant families of natural products through sequence-guided screening of soil metagenomes” Angew. Chem., Int. Ed. 2013, 52, 11063.
-
(2013)
Angew. Chem., Int. Ed
, vol.52
, pp. 11063
-
-
Kang, H.S.1
Brady, S.F.2
-
159
-
-
84893399750
-
Functional analysis of environmental DNA-derived microviridins provides new insights into the diversity of the tricyclic peptide family
-
Gatte-Picchi, D.; Weiz, A.; Ishida, K.; Hertweck, C.; Dittmann, E. “Functional analysis of environmental DNA-derived microviridins provides new insights into the diversity of the tricyclic peptide family” Appl. Environ. Microbiol. 2014, 80, 1380.
-
(2014)
Appl. Environ. Microbiol
, vol.80
, pp. 1380
-
-
Gatte-Picchi, D.1
Weiz, A.2
Ishida, K.3
Hertweck, C.4
Dittmann, E.5
-
160
-
-
77953045048
-
Exploiting the natural diversity of microviridin gene clusters for discovery of novel tricyclic depsipeptides
-
Ziemert, N.; Ishida, K.; Weiz, A.; Hertweck, C.; Dittmann, E. “Exploiting the natural diversity of microviridin gene clusters for discovery of novel tricyclic depsipeptides” Appl. Environ. Microbiol. 2010, 76, 3568.
-
(2010)
Appl. Environ. Microbiol
, vol.76
, pp. 3568
-
-
Ziemert, N.1
Ishida, K.2
Weiz, A.3
Hertweck, C.4
Dittmann, E.5
-
161
-
-
84870714378
-
Tetarimycin A, an MRSA-active antibiotic identified through induced expression of environmental DNA gene clusters
-
Kallifidas, D.; Kang, H. S.; Brady, S. F. “Tetarimycin A, an MRSA-active antibiotic identified through induced expression of environmental DNA gene clusters” J. Am. Chem. Soc. 2012, 134, 19552.
-
(2012)
J. Am. Chem. Soc
, vol.134
, pp. 19552
-
-
Kallifidas, D.1
Kang, H.S.2
Brady, S.F.3
-
162
-
-
79961225518
-
Functional analysis of environmental DNA-derived type II polyketide synthases reveals structurally diverse secondary metabolites
-
Feng, Z.; Kallifidas, D.; Brady, S. F. “Functional analysis of environmental DNA-derived type II polyketide synthases reveals structurally diverse secondary metabolites” Proc. Natl. Acad. Sci. U.S.A. 2011, 108, 12629.
-
(2011)
Proc. Natl. Acad. Sci. U.S.A
, vol.108
, pp. 12629
-
-
Feng, Z.1
Kallifidas, D.2
Brady, S.F.3
-
163
-
-
70349923903
-
An environmental DNAderived type II polyketide biosynthetic pathway encodes the biosynthesis of the pentacyclic polyketide erdacin
-
King, R. W.; Bauer, J. D.; Brady, S. F. “An environmental DNAderived type II polyketide biosynthetic pathway encodes the biosynthesis of the pentacyclic polyketide erdacin” Angew. Chem., Int. Ed. 2009, 48, 6257.
-
(2009)
Angew. Chem., Int. Ed
, vol.48
, pp. 6257
-
-
King, R.W.1
Bauer, J.D.2
Brady, S.F.3
-
164
-
-
77952997484
-
Utahmycins A and B, azaquinones produced by an environmental DNA clone
-
Bauer, J. D.; King, R. W.; Brady, S. F. “Utahmycins A and B, azaquinones produced by an environmental DNA clone” J. Nat. Prod. 2010, 73, 976.
-
(2010)
J. Nat. Prod
, vol.73
, pp. 976
-
-
Bauer, J.D.1
King, R.W.2
Brady, S.F.3
-
165
-
-
84903218940
-
Arixanthomycins A-C: Phylogenyguided discovery of biologically active eDNA-derived pentangular polyphenols
-
Kang, H. S.; Brady, S. F. “Arixanthomycins A-C: phylogenyguided discovery of biologically active eDNA-derived pentangular polyphenols” ACS Chem. Biol. 2014, 9, 1267.
-
(2014)
ACS Chem. Biol
, vol.9
, pp. 1267
-
-
Kang, H.S.1
Brady, S.F.2
-
166
-
-
84878258173
-
Metagenomic approaches for exploiting uncultivated bacteria as a resource for novel biosynthetic enzymology
-
Wilson, M. C.; Piel, J. “Metagenomic approaches for exploiting uncultivated bacteria as a resource for novel biosynthetic enzymology” Chem. Biol. 2013, 20, 636.
-
(2013)
Chem. Biol
, vol.20
, pp. 636
-
-
Wilson, M.C.1
Piel, J.2
-
167
-
-
84895073235
-
Isolation and structural characterization of capistruin, a lasso peptide predicted from the genome sequence of Burkholderia thailandensis E264
-
Knappe, T.; Linne, U.; Zirah, S.; Rebuffat, S.; Xie, X. L.; Marahiel, M. “Isolation and structural characterization of capistruin, a lasso peptide predicted from the genome sequence of Burkholderia thailandensis E264” J. Pept. Sci. 2008, 14, 97.
-
(2008)
J. Pept. Sci
, vol.14
, pp. 97
-
-
Knappe, T.1
Linne, U.2
Zirah, S.3
Rebuffat, S.4
Xie, X.L.5
Marahiel, M.6
-
168
-
-
18844410256
-
Patellamide A and C biosynthesis by a microcin-like pathway in Prochloron didemni, the cyanobacterial symbiont of Lissoclinum patella
-
Schmidt, E. W.; Nelson, J. T.; Rasko, D. A.; Sudek, S.; Eisen, J. A.; Haygood, M. G.; Ravel, J. “Patellamide A and C biosynthesis by a microcin-like pathway in Prochloron didemni, the cyanobacterial symbiont of Lissoclinum patella” Proc. Natl. Acad. Sci. U.S.A. 2005, 102, 7315.
-
(2005)
Proc. Natl. Acad. Sci. U.S.A
, vol.102
, pp. 7315
-
-
Schmidt, E.W.1
Nelson, J.T.2
Rasko, D.A.3
Sudek, S.4
Eisen, J.A.5
Haygood, M.G.6
Ravel, J.7
-
169
-
-
26944437043
-
Shotgun cloning and heterologous expression of the patellamide gene cluster as a strategy to achieving sustained metabolite production
-
Long, P. F.; Dunlap, W. C.; Battershill, C. N.; Jaspars, M. “Shotgun cloning and heterologous expression of the patellamide gene cluster as a strategy to achieving sustained metabolite production” ChemBioChem 2005, 6, 1760.
-
(2005)
Chembiochem
, vol.6
, pp. 1760
-
-
Long, P.F.1
Dunlap, W.C.2
Battershill, C.N.3
Jaspars, M.4
-
170
-
-
0842306927
-
Largescale synthesis of the anti-cancer marine natural product (+)- discodermolide. Part 5: Linkage of fragments C1-6 and C7-24 and finale
-
Mickel, S. J.; Niederer, D.; Daeffler, R.; Osmani, A.; Kuesters, E.; Schmid, E.; Schaer, K.; Gamboni, R.; Chen, W.; Loeser, E.; Kinder, F. R.; Konigsberger, K.; Prasad, K.; Ramsey, T. M.; Repič, O.; Wang, R.-M.; Florence, G.; Lyothier, I.; Paterson, I. “Largescale synthesis of the anti-cancer marine natural product (+)- discodermolide. Part 5: linkage of fragments C1-6 and C7-24 and finale” Org. Process Res. Dev. 2004, 8, 122.
-
(2004)
Org. Process Res. Dev
, vol.8
, pp. 122
-
-
Mickel, S.J.1
Niederer, D.2
Daeffler, R.3
Osmani, A.4
Kuesters, E.5
Schmid, E.6
Schaer, K.7
Gamboni, R.8
Chen, W.9
Loeser, E.10
Kinder, F.R.11
Konigsberger, K.12
Prasad, K.13
Ramsey, T.M.14
Repič, O.15
Wang, R.-M.16
Florence, G.17
Lyothier, I.18
Paterson, I.19
-
171
-
-
0025160288
-
Discodermolide - a new bioactive polyhydroxylated lactone from the marine sponge Discodermia dissoluta
-
Gunasekera, S. P.; Gunasekera, M.; Longley, R. E.; Schulte, G. K. “Discodermolide - a new bioactive polyhydroxylated lactone from the marine sponge Discodermia dissoluta” J. Org. Chem. 1990, 55, 4912.
-
(1990)
J. Org. Chem
, vol.55
, pp. 4912
-
-
Gunasekera, S.P.1
Gunasekera, M.2
Longley, R.E.3
Schulte, G.K.4
-
172
-
-
67650281479
-
Polyketide assembly lines of uncultivated sponge symbionts from structure-based gene targeting
-
Fisch, K. M.; Gurgui, C.; Heycke, N.; van der Sar, S. A.; Anderson, S. A.; Webb, V. L.; Taudien, S.; Platzer, M.; Rubio, B. K.; Robinson, S. J.; Crews, P.; Piel, J. “Polyketide assembly lines of uncultivated sponge symbionts from structure-based gene targeting” Nat. Chem. Biol. 2009, 5, 494.
-
(2009)
Nat. Chem. Biol
, vol.5
, pp. 494
-
-
Fisch, K.M.1
Gurgui, C.2
Heycke, N.3
van der Sar, S.A.4
Anderson, S.A.5
Webb, V.L.6
Taudien, S.7
Platzer, M.8
Rubio, B.K.9
Robinson, S.J.10
Crews, P.11
Piel, J.12
-
173
-
-
3042706094
-
Psymberin, a potent sponge-derived cytotoxin from Psammocinia distantly related to the pederin family
-
Cichewicz, R. H.; Valeriote, F. A.; Crews, P. “Psymberin, a potent sponge-derived cytotoxin from Psammocinia distantly related to the pederin family” Org. Lett. 2004, 6, 1951.
-
(2004)
Org. Lett
, vol.6
, pp. 1951
-
-
Cichewicz, R.H.1
Valeriote, F.A.2
Crews, P.3
-
174
-
-
21044448952
-
Daptomycin biosynthesis in Streptomyces roseosporus: Cloning and analysis of the gene cluster and revision of peptide stereochemistry
-
Miao, V.; Coeffet-LeGal, M. F.; Brian, P.; Brost, R.; Penn, J.; Whiting, A.; Martin, S.; Ford, R.; Parr, I.; Bouchard, M.; Silva, C. J.; Wrigley, S. K.; Baltz, R. H. “Daptomycin biosynthesis in Streptomyces roseosporus: cloning and analysis of the gene cluster and revision of peptide stereochemistry” Microbiology 2005, 151, 1507.
-
(2005)
Microbiology
, vol.151
, pp. 1507
-
-
Miao, V.1
Coeffet-Legal, M.F.2
Brian, P.3
Brost, R.4
Penn, J.5
Whiting, A.6
Martin, S.7
Ford, R.8
Parr, I.9
Bouchard, M.10
Silva, C.J.11
Wrigley, S.K.12
Baltz, R.H.13
-
175
-
-
0027436431
-
A new antibiotic, cypemycin. Taxonomy, fermentation, isolation and biological characteristics
-
Komiyama, K.; Otoguro, K.; Segawa, T.; Shiomi, K.; Yang, H.; Takahashi, Y.; Hayashi, M.; Otani, T.; Omura, S. “A new antibiotic, cypemycin. Taxonomy, fermentation, isolation and biological characteristics” J. Antibiot. 1993, 46, 1666.
-
(1993)
J. Antibiot
, vol.46
, pp. 1666
-
-
Komiyama, K.1
Otoguro, K.2
Segawa, T.3
Shiomi, K.4
Yang, H.5
Takahashi, Y.6
Hayashi, M.7
Otani, T.8
Omura, S.9
-
176
-
-
0027944430
-
Structure of cypemycin, a new peptide antibiotic
-
Minami, Y.; Yoshida, K.-i.; Azuma, R.; Urakawa, A.; Kawauchi, T.; Otani, T.; Komiyama, K.; Ōmura, S. “Structure of cypemycin, a new peptide antibiotic” Tetrahedron Lett. 1994, 35, 8001.
-
(1994)
Tetrahedron Lett
, vol.35
, pp. 8001
-
-
Minami, Y.1
Yoshida, K.-I.2
Azuma, R.3
Urakawa, A.4
Kawauchi, T.5
Otani, T.6
Komiyama, K.7
Ōmura, S.8
-
177
-
-
77958012949
-
Genome mining and genetic analysis of cypemycin biosynthesis reveal an unusual class of posttranslationally modified peptides
-
Claesen, J.; Bibb, M. “Genome mining and genetic analysis of cypemycin biosynthesis reveal an unusual class of posttranslationally modified peptides” Proc. Natl. Acad. Sci. U.S.A. 2010, 107, 16297.
-
(2010)
Proc. Natl. Acad. Sci. U.S.A
, vol.107
, pp. 16297
-
-
Claesen, J.1
Bibb, M.2
-
178
-
-
79956067794
-
Biosynthesis and regulation of grisemycin, a new member of the linaridin family of ribosomally synthesized peptides produced by Streptomyces griseus IFO 13350
-
Claesen, J.; Bibb, M. J. “Biosynthesis and regulation of grisemycin, a new member of the linaridin family of ribosomally synthesized peptides produced by Streptomyces griseus IFO 13350” J. Bacteriol. 2011, 193, 2510.
-
(2011)
J. Bacteriol
, vol.193
, pp. 2510
-
-
Claesen, J.1
Bibb, M.J.2
-
179
-
-
84896737390
-
A glycosylated, labionin-containing lanthipeptide with marked antinociceptive activity
-
Iorio, M.; Sasso, O.; Maffioli, S. I.; Bertorelli, R.; Monciardini, P.; Sosio, M.; Bonezzi, F.; Summa, M.; Brunati, C.; Bordoni, R.; Corti, G.; Tarozzo, G.; Piomelli, D.; Reggiani, A.; Donadio, S. “A glycosylated, labionin-containing lanthipeptide with marked antinociceptive activity” ACS Chem. Biol. 2014, 9, 398.
-
(2014)
ACS Chem. Biol
, vol.9
, pp. 398
-
-
Iorio, M.1
Sasso, O.2
Maffioli, S.I.3
Bertorelli, R.4
Monciardini, P.5
Sosio, M.6
Bonezzi, F.7
Summa, M.8
Brunati, C.9
Bordoni, R.10
Corti, G.11
Tarozzo, G.12
Piomelli, D.13
Reggiani, A.14
Donadio, S.15
-
180
-
-
69949191291
-
Ribosomally synthesized thiopeptide antibiotics targeting elongation factor Tu
-
Morris, R. P.; Leeds, J. A.; Naegeli, H. U.; Oberer, L.; Memmert, K.; Weber, E.; LaMarche, M. J.; Parker, C. N.; Burrer, N.; Esterow, S.; Hein, A. E.; Schmitt, E. K.; Krastel, P. “Ribosomally synthesized thiopeptide antibiotics targeting elongation factor Tu” J. Am. Chem. Soc. 2009, 131, 5946.
-
(2009)
J. Am. Chem. Soc
, vol.131
, pp. 5946
-
-
Morris, R.P.1
Leeds, J.A.2
Naegeli, H.U.3
Oberer, L.4
Memmert, K.5
Weber, E.6
Lamarche, M.J.7
Parker, C.N.8
Burrer, N.9
Esterow, S.10
Hein, A.E.11
Schmitt, E.K.12
Krastel, P.13
-
181
-
-
67749113468
-
Thiostrepton biosynthesis: Prototype for a new family of bacteriocins
-
Kelly, W. L.; Pan, L.; Li, C. “Thiostrepton biosynthesis: prototype for a new family of bacteriocins” J. Am. Chem. Soc. 2009, 131, 4327.
-
(2009)
J. Am. Chem. Soc
, vol.131
, pp. 4327
-
-
Kelly, W.L.1
Pan, L.2
Li, C.3
-
182
-
-
60549109637
-
Thiopeptide biosynthesis featuring ribosomally synthesized precursor peptides and conserved posttranslational modifications
-
Liao, R.; Duan, L.; Lei, C.; Pan, H.; Ding, Y.; Zhang, Q.; Chen, D.; Shen, B.; Yu, Y.; Liu, W. “Thiopeptide biosynthesis featuring ribosomally synthesized precursor peptides and conserved posttranslational modifications” Chem. Biol. 2009, 16, 141.
-
(2009)
Chem. Biol
, vol.16
, pp. 141
-
-
Liao, R.1
Duan, L.2
Lei, C.3
Pan, H.4
Ding, Y.5
Zhang, Q.6
Chen, D.7
Shen, B.8
Yu, Y.9
Liu, W.10
-
183
-
-
62449284698
-
Thirteen posttranslational modifications convert a 14-residue peptide into the antibiotic thiocillin
-
Wieland Brown, L. C.; Acker, M. G.; Clardy, J.; Walsh, C. T.; Fischbach, M. A. “Thirteen posttranslational modifications convert a 14-residue peptide into the antibiotic thiocillin” Proc. Natl. Acad. Sci. U.S.A. 2009, 106, 2549.
-
(2009)
Proc. Natl. Acad. Sci. U.S.A
, vol.106
, pp. 2549
-
-
Wieland Brown, L.C.1
Acker, M.G.2
Clardy, J.3
Walsh, C.T.4
Fischbach, M.A.5
-
184
-
-
84870602622
-
How thiostrepton was made in the laboratory
-
Nicolaou, K. C. “How thiostrepton was made in the laboratory” Angew. Chem., Int. Ed. 2012, 51, 12414.
-
(2012)
Angew. Chem., Int. Ed
, vol.51
, pp. 12414
-
-
Nicolaou, K.C.1
-
185
-
-
77049246278
-
Thiostrepton, a new antibiotic. II. Isolation and chemical characterization
-
Dutcher, J. D.; Vandeputte, J. “Thiostrepton, a new antibiotic. II. Isolation and chemical characterization” Antibiot. Annu. 1955, 3, 560.
-
(1955)
Antibiot. Annu
, vol.3
, pp. 560
-
-
Dutcher, J.D.1
Vandeputte, J.2
-
186
-
-
84912135345
-
Nucleophilic 1,4-additions for natural product discovery
-
Cox, C. L.; Tietz, J. I.; Sokolowski, K.; Melby, J. O.; Doroghazi, J. R.; Mitchell, D. A. “Nucleophilic 1,4-additions for natural product discovery” ACS Chem. Biol. 2014, 9, 2014.
-
(2014)
ACS Chem. Biol
, vol.9
, pp. 2014
-
-
Cox, C.L.1
Tietz, J.I.2
Sokolowski, K.3
Melby, J.O.4
Doroghazi, J.R.5
Mitchell, D.A.6
-
187
-
-
84938529895
-
Structure and biosynthetic assembly of gulmirecins, macrolide antibiotics from the predatory bacterium Pyxidicoccus fallax
-
Schieferdecker, S.; Konig, S.; Weigel, C.; Dahse, H. M.; Werz, O.; Nett, M. “Structure and biosynthetic assembly of gulmirecins, macrolide antibiotics from the predatory bacterium Pyxidicoccus fallax” Chem. Eur. J. 2014, 20, 15933.
-
(2014)
Chem. Eur. J
, vol.20
, pp. 15933
-
-
Schieferdecker, S.1
Konig, S.2
Weigel, C.3
Dahse, H.M.4
Werz, O.5
Nett, M.6
-
188
-
-
59649084249
-
How nature morphs peptide scaffolds into antibiotics
-
Nolan, E. M.; Walsh, C. T. “How nature morphs peptide scaffolds into antibiotics” ChemBioChem 2009, 10, 34.
-
(2009)
Chembiochem
, vol.10
, pp. 34
-
-
Nolan, E.M.1
Walsh, C.T.2
-
189
-
-
80054865417
-
A mass spectrometry-guided genome mining approach for natural product peptidogenomics
-
Kersten, R. D.; Yang, Y. L.; Xu, Y. Q.; Cimermancic, P.; Nam, S. J.; Fenical, W.; Fischbach, M. A.; Moore, B. S.; Dorrestein, P. C. “A mass spectrometry-guided genome mining approach for natural product peptidogenomics” Nat. Chem. Biol. 2011, 7, 794.
-
(2011)
Nat. Chem. Biol
, vol.7
, pp. 794
-
-
Kersten, R.D.1
Yang, Y.L.2
Xu, Y.Q.3
Cimermancic, P.4
Nam, S.J.5
Fenical, W.6
Fischbach, M.A.7
Moore, B.S.8
Dorrestein, P.C.9
-
190
-
-
0033434080
-
Probability-based protein identification by searching sequence databases using mass spectrometry data
-
Perkins, D. N.; Pappin, D. J.; Creasy, D. M.; Cottrell, J. S. “Probability-based protein identification by searching sequence databases using mass spectrometry data” Electrophoresis 1999, 20, 3551.
-
(1999)
Electrophoresis
, vol.20
, pp. 3551
-
-
Perkins, D.N.1
Pappin, D.J.2
Creasy, D.M.3
Cottrell, J.S.4
-
191
-
-
28644447919
-
Identification of post-translational modifications by blind search of mass spectra
-
Tsur, D.; Tanner, S.; Zandi, E.; Bafna, V.; Pevzner, P. A. “Identification of post-translational modifications by blind search of mass spectra” Nat. Biotechnol. 2005, 23, 1562.
-
(2005)
Nat. Biotechnol
, vol.23
, pp. 1562
-
-
Tsur, D.1
Tanner, S.2
Zandi, E.3
Bafna, V.4
Pevzner, P.A.5
-
192
-
-
80755172598
-
Imaging mass spectrometry and genome mining via short sequence tagging identified the anti-infective agent arylomycin in Streptomyces roseosporus
-
Liu, W. T.; Kersten, R. D.; Yang, Y. L.; Moore, B. S.; Dorrestein, P. C. “Imaging mass spectrometry and genome mining via short sequence tagging identified the anti-infective agent arylomycin in Streptomyces roseosporus” J. Am. Chem. Soc. 2011, 133, 18010.
-
(2011)
J. Am. Chem. Soc
, vol.133
, pp. 18010
-
-
Liu, W.T.1
Kersten, R.D.2
Yang, Y.L.3
Moore, B.S.4
Dorrestein, P.C.5
-
193
-
-
84862999012
-
Mass spectral molecular networking of living microbial colonies
-
Watrous, J.; Roach, P.; Alexandrov, T.; Heath, B. S.; Yang, J. Y.; Kersten, R. D.; van der Voort, M.; Pogliano, K.; Gross, H.; Raaijmakers, J. M.; Moore, B. S.; Laskin, J.; Bandeira, N.; Dorrestein, P. C. “Mass spectral molecular networking of living microbial colonies” Proc. Natl. Acad. Sci. U.S.A. 2012, 109, E1743.
-
(2012)
Proc. Natl. Acad. Sci. U.S.A
, vol.109
-
-
Watrous, J.1
Roach, P.2
Alexandrov, T.3
Heath, B.S.4
Yang, J.Y.5
Kersten, R.D.6
van der Voort, M.7
Pogliano, K.8
Gross, H.9
Raaijmakers, J.M.10
Moore, B.S.11
Laskin, J.12
Bandeira, N.13
Dorrestein, P.C.14
-
194
-
-
84893132507
-
MS/MSbased networking and peptidogenomics guided genome mining revealed the stenothricin gene cluster in Streptomyces roseosporus
-
Liu, W. T.; Lamsa, A.; Wong, W. R.; Boudreau, P. D.; Kersten, R.; Peng, Y.; Moree, W. J.; Duggan, B. M.; Moore, B. S.; Gerwick, W. H.; Linington, R. G.; Pogliano, K.; Dorrestein, P. C. “MS/MSbased networking and peptidogenomics guided genome mining revealed the stenothricin gene cluster in Streptomyces roseosporus” J. Antibiot. 2014, 67, 99.
-
(2014)
J. Antibiot
, vol.67
, pp. 99
-
-
Liu, W.T.1
Lamsa, A.2
Wong, W.R.3
Boudreau, P.D.4
Kersten, R.5
Peng, Y.6
Moree, W.J.7
Duggan, B.M.8
Moore, B.S.9
Gerwick, W.H.10
Linington, R.G.11
Pogliano, K.12
Dorrestein, P.C.13
-
195
-
-
0016381013
-
Metabolic products of microorganisms. 134. Stenothricin, a new inhibitor of the bacterial cell wall synthesis
-
Hasenbohler, A.; Kneifel, H.; Konig, W. A.; Zahner, H.; Zeiler, H. J. “Metabolic products of microorganisms. 134. Stenothricin, a new inhibitor of the bacterial cell wall synthesis” Arch. Microbiol. 1974, 99, 307.
-
(1974)
Arch. Microbiol
, vol.99
, pp. 307
-
-
Hasenbohler, A.1
Kneifel, H.2
Konig, W.A.3
Zahner, H.4
Zeiler, H.J.5
-
196
-
-
79957595286
-
Deciphering the rhizosphere microbiome for disease-suppressive bacteria
-
Mendes, R.; Kruijt, M.; de Bruijn, I.; Dekkers, E.; van der Voort, M.; Schneider, J. H.; Piceno, Y. M.; DeSantis, T. Z.; Andersen, G. L.; Bakker, P. A.; Raaijmakers, J. M. “Deciphering the rhizosphere microbiome for disease-suppressive bacteria” Science 2011, 332, 1097.
-
(2011)
Science
, vol.332
, pp. 1097
-
-
Mendes, R.1
Kruijt, M.2
de Bruijn, I.3
Dekkers, E.4
van der Voort, M.5
Schneider, J.H.6
Piceno, Y.M.7
Desantis, T.Z.8
Andersen, G.L.9
Bakker, P.A.10
Raaijmakers, J.M.11
-
197
-
-
84879908779
-
MS/MS networking guided analysis of molecule and gene cluster families
-
Nguyen, D. D.; Wu, C. H.; Moree, W. J.; Lamsa, A.; Medema, M. H.; Zhao, X. L.; Gavilan, R. G.; Aparicio, M.; Atencio, L.; Jackson, C.; Ballesteros, J.; Sanchez, J.; Watrous, J. D.; Phelan, V. V.; van de Wiel, C.; Kersten, R. D.; Mehnaz, S.; De Mot, R.; Shank, E. A.; Charusanti, P.; Nagarajan, H.; Duggan, B. M.; Moore, B. S.; Bandeira, N.; Palsson, B. O.; Pogliano, K.; Gutierrez, M.; Dorrestein, P. C. “MS/MS networking guided analysis of molecule and gene cluster families” Proc. Natl. Acad. Sci. U.S.A. 2013, 110, E2611.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A
, vol.110
-
-
Nguyen, D.D.1
Wu, C.H.2
Moree, W.J.3
Lamsa, A.4
Medema, M.H.5
Zhao, X.L.6
Gavilan, R.G.7
Aparicio, M.8
Atencio, L.9
Jackson, C.10
Ballesteros, J.11
Sanchez, J.12
Watrous, J.D.13
Phelan, V.V.14
Van De Wiel, C.15
Kersten, R.D.16
Mehnaz, S.17
de Mot, R.18
Shank, E.A.19
Charusanti, P.20
Nagarajan, H.21
Duggan, B.M.22
Moore, B.S.23
Bandeira, N.24
Palsson, B.O.25
Pogliano, K.26
Gutierrez, M.27
Dorrestein, P.C.28
more..
-
198
-
-
68349086897
-
Dereplication and de novo sequencing of nonribosomal peptides
-
Ng, J.; Bandeira, N.; Liu, W. T.; Ghassemian, M.; Simmons, T. L.; Gerwick, W. H.; Linington, R.; Dorrestein, P. C.; Pevzner, P. A. “Dereplication and de novo sequencing of nonribosomal peptides” Nat. Methods 2009, 6, 596.
-
(2009)
Nat. Methods
, vol.6
, pp. 596
-
-
Ng, J.1
Bandeira, N.2
Liu, W.T.3
Ghassemian, M.4
Simmons, T.L.5
Gerwick, W.H.6
Linington, R.7
Dorrestein, P.C.8
Pevzner, P.A.9
-
199
-
-
70349959824
-
A proteomics approach to discovering natural products and their biosynthetic pathways
-
Bumpus, S. B.; Evans, B. S.; Thomas, P. M.; Ntai, I.; Kelleher, N. L. “A proteomics approach to discovering natural products and their biosynthetic pathways” Nat. Biotechnol. 2009, 27, 951.
-
(2009)
Nat. Biotechnol
, vol.27
, pp. 951
-
-
Bumpus, S.B.1
Evans, B.S.2
Thomas, P.M.3
Ntai, I.4
Kelleher, N.L.5
-
200
-
-
84903172568
-
Natural product proteomining, a quantitative proteomics platform, allows rapid discovery of biosynthetic gene clusters for different classes of natural products
-
Gubbens, J.; Zhu, H.; Girard, G.; Song, L.; Florea, B. I.; Aston, P.; Ichinose, K.; Filippov, D. V.; Choi, Y. H.; Overkleeft, H. S.; Challis, G. L.; van Wezel, G. P. “Natural product proteomining, a quantitative proteomics platform, allows rapid discovery of biosynthetic gene clusters for different classes of natural products” Chem. Biol. 2014, 21, 707.
-
(2014)
Chem. Biol
, vol.21
, pp. 707
-
-
Gubbens, J.1
Zhu, H.2
Girard, G.3
Song, L.4
Florea, B.I.5
Aston, P.6
Ichinose, K.7
Filippov, D.V.8
Choi, Y.H.9
Overkleeft, H.S.10
Challis, G.L.11
Van Wezel, G.P.12
-
201
-
-
84871740117
-
Gobichelin A and B: Mixedligand siderophores discovered using proteomics
-
Chen, Y. Q.; Unger, M.; Ntai, I.; McClure, R. A.; Albright, J. C.; Thomson, R. J.; Kelleher, N. L. “Gobichelin A and B: mixedligand siderophores discovered using proteomics” Medchemcomm 2013, 4, 233.
-
(2013)
Medchemcomm
, vol.4
, pp. 233
-
-
Chen, Y.Q.1
Unger, M.2
Ntai, I.3
McClure, R.A.4
Albright, J.C.5
Thomson, R.J.6
Kelleher, N.L.7
-
202
-
-
79955924618
-
Proteomics-based discovery of koranimine, a cyclic imine natural product
-
Evans, B. S.; Ntai, I.; Chen, Y. Q.; Robinson, S. J.; Kelleher, N. L. “Proteomics-based discovery of koranimine, a cyclic imine natural product” J. Am. Chem. Soc. 2011, 133, 7316.
-
(2011)
J. Am. Chem. Soc
, vol.133
, pp. 7316
-
-
Evans, B.S.1
Ntai, I.2
Chen, Y.Q.3
Robinson, S.J.4
Kelleher, N.L.5
-
203
-
-
84862907959
-
A proteomic survey of nonribosomal peptide and polyketide biosynthesis in Actinobacteria
-
Chen, Y. Q.; Ntai, I.; Ju, K. S.; Unger, M.; Zamdborg, L.; Robinson, S. J.; Doroghazi, J. R.; Labeda, D. P.; Metcalf, W. W.; Kelleher, N. L. “A proteomic survey of nonribosomal peptide and polyketide biosynthesis in Actinobacteria” J. Proteome Res. 2012, 11, 85.
-
(2012)
J. Proteome Res
, vol.11
, pp. 85
-
-
Chen, Y.Q.1
Ntai, I.2
Ju, K.S.3
Unger, M.4
Zamdborg, L.5
Robinson, S.J.6
Doroghazi, J.R.7
Labeda, D.P.8
Metcalf, W.W.9
Kelleher, N.L.10
-
204
-
-
84880375444
-
Proteomics guided discovery of flavopeptins: Antiproliferative aldehydes synthesized by a reductase domaincontaining non-ribosomal peptide synthetase
-
Chen, Y. Q.; McClure, R. A.; Zheng, Y. P.; Thomson, R. J.; Kelleher, N. L. “Proteomics guided discovery of flavopeptins: antiproliferative aldehydes synthesized by a reductase domaincontaining non-ribosomal peptide synthetase” J. Am. Chem. Soc. 2013, 135, 10449.
-
(2013)
J. Am. Chem. Soc
, vol.135
, pp. 10449
-
-
Chen, Y.Q.1
McClure, R.A.2
Zheng, Y.P.3
Thomson, R.J.4
Kelleher, N.L.5
-
205
-
-
84892852768
-
Thiopeptide antibiotics: Retrospective and recent advances
-
Just-Baringo, X.; Albericio, F.; Alvarez, M. “Thiopeptide antibiotics: retrospective and recent advances” Mar. Drugs 2014, 12, 317.
-
(2014)
Mar. Drugs
, vol.12
, pp. 317
-
-
Just-Baringo, X.1
Albericio, F.2
Alvarez, M.3
-
206
-
-
55749106422
-
Structure elucidation and biosynthesis of fuscachelins, peptide siderophores from the moderate thermophile Thermobifida fusca
-
Dimise, E. J.; Widboom, P. F.; Bruner, S. D. “Structure elucidation and biosynthesis of fuscachelins, peptide siderophores from the moderate thermophile Thermobifida fusca” Proc. Natl. Acad. Sci. U.S.A. 2008, 105, 15311.
-
(2008)
Proc. Natl. Acad. Sci. U.S.A
, vol.105
, pp. 15311
-
-
Dimise, E.J.1
Widboom, P.F.2
Bruner, S.D.3
-
207
-
-
81555208983
-
Meta-omic characterization of the marine invertebrate microbial consortium that produces the chemotherapeutic natural product ET-743
-
Rath, C. M.; Janto, B.; Earl, J.; Ahmed, A.; Hu, F. Z.; Hiller, L.; Dahlgren, M.; Kreft, R.; Yu, F. A.; Wolff, J. J.; Kweon, H. K.; Christiansen, M. A.; Hakansson, K.; Williams, R. M.; Ehrlich, G. D.; Sherman, D. H. “Meta-omic characterization of the marine invertebrate microbial consortium that produces the chemotherapeutic natural product ET-743” ACS Chem. Biol. 2011, 6, 1244.
-
(2011)
ACS Chem. Biol
, vol.6
, pp. 1244
-
-
Rath, C.M.1
Janto, B.2
Earl, J.3
Ahmed, A.4
Hu, F.Z.5
Hiller, L.6
Dahlgren, M.7
Kreft, R.8
Yu, F.A.9
Wolff, J.J.10
Kweon, H.K.11
Christiansen, M.A.12
Hakansson, K.13
Williams, R.M.14
Ehrlich, G.D.15
Sherman, D.H.16
-
208
-
-
33847029508
-
Identification of the putative bryostatin polyketide synthase gene cluster from “Candidatus Endobugula sertula”, the uncultivated microbial symbiont of the marine bryozoan Bugula neritina
-
Sudek, S.; Lopanik, N. B.; Waggoner, L. E.; Hildebrand, M.; Anderson, C.; Liu, H.; Patel, A.; Sherman, D. H.; Haygood, M. G. “Identification of the putative bryostatin polyketide synthase gene cluster from “Candidatus Endobugula sertula”, the uncultivated microbial symbiont of the marine bryozoan Bugula neritina” J. Nat. Prod. 2007, 70, 67.
-
(2007)
J. Nat. Prod
, vol.70
, pp. 67
-
-
Sudek, S.1
Lopanik, N.B.2
Waggoner, L.E.3
Hildebrand, M.4
Anderson, C.5
Liu, H.6
Patel, A.7
Sherman, D.H.8
Haygood, M.G.9
-
209
-
-
34447302758
-
Genome sequencing reveals complex secondary metabolome in the marine actinomycete Salinispora tropica
-
Udwary, D. W.; Zeigler, L.; Asolkar, R. N.; Singan, V.; Lapidus, A.; Fenical, W.; Jensen, P. R.; Moore, B. S. “Genome sequencing reveals complex secondary metabolome in the marine actinomycete Salinispora tropica” Proc. Natl. Acad. Sci. U.S.A. 2007, 104, 10376.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A
, vol.104
, pp. 10376
-
-
Udwary, D.W.1
Zeigler, L.2
Asolkar, R.N.3
Singan, V.4
Lapidus, A.5
Fenical, W.6
Jensen, P.R.7
Moore, B.S.8
-
210
-
-
84906328199
-
Structural investigation of ribosomally synthesized natural products by hypothetical structure enumeration and evaluation using tandem MS
-
Zhang, Q.; Ortega, M.; Shi, Y. X.; Wang, H.; Melby, J. O.; Tang, W. X.; Mitchell, D. A.; van der Donk, W. A. “Structural investigation of ribosomally synthesized natural products by hypothetical structure enumeration and evaluation using tandem MS” Proc. Natl. Acad. Sci. U.S.A. 2014, 111, 12031.
-
(2014)
Proc. Natl. Acad. Sci. U.S.A
, vol.111
, pp. 12031
-
-
Zhang, Q.1
Ortega, M.2
Shi, Y.X.3
Wang, H.4
Melby, J.O.5
Tang, W.X.6
Mitchell, D.A.7
van der Donk, W.A.8
-
211
-
-
38349060901
-
Determining the structure and mode of action of microbisporicin, a potent lantibiotic active against multiresistant pathogens
-
Castiglione, F.; Lazzarini, A.; Carrano, L.; Corti, E.; Ciciliato, I.; Gastaldo, L.; Candiani, P.; Losi, D.; Marinelli, F.; Selva, E.; Parenti, F. “Determining the structure and mode of action of microbisporicin, a potent lantibiotic active against multiresistant pathogens” Chem. Biol. 2008, 15, 22.
-
(2008)
Chem. Biol
, vol.15
, pp. 22
-
-
Castiglione, F.1
Lazzarini, A.2
Carrano, L.3
Corti, E.4
Ciciliato, I.5
Gastaldo, L.6
Candiani, P.7
Losi, D.8
Marinelli, F.9
Selva, E.10
Parenti, F.11
-
212
-
-
77955814236
-
Microbisporicin gene cluster reveals unusual features of lantibiotic biosynthesis in actinomycetes
-
Foulston, L. C.; Bibb, M. J. “Microbisporicin gene cluster reveals unusual features of lantibiotic biosynthesis in actinomycetes” Proc. Natl. Acad. Sci. U.S.A. 2010, 107, 13461.
-
(2010)
Proc. Natl. Acad. Sci. U.S.A
, vol.107
, pp. 13461
-
-
Foulston, L.C.1
Bibb, M.J.2
-
213
-
-
84923210977
-
Structure, bioactivity, and resistance mechanism of streptomonomicin, an unusual lasso peptide from an understudied halophilic actinomycete
-
Metelev, M.; Tietz, J. I.; Melby, J. O.; Blair, P. M.; Zhu, L.; Livnat, I.; Severinov, K.; Mitchell, D. A. “Structure, bioactivity, and resistance mechanism of streptomonomicin, an unusual lasso peptide from an understudied halophilic actinomycete” Chem. Biol. 2015.
-
(2015)
Chem. Biol
-
-
Metelev, M.1
Tietz, J.I.2
Melby, J.O.3
Blair, P.M.4
Zhu, L.5
Livnat, I.6
Severinov, K.7
Mitchell, D.A.8
-
215
-
-
84864990340
-
Lasso peptides: Structure, function, biosynthesis, and engineering
-
Maksimov, M. O.; Pan, S. J.; Link, A. J. “Lasso peptides: structure, function, biosynthesis, and engineering” Nat. Prod. Rep. 2012, 29, 996.
-
(2012)
Nat. Prod. Rep
, vol.29
, pp. 996
-
-
Maksimov, M.O.1
Pan, S.J.2
Link, A.J.3
-
216
-
-
84922937832
-
A new antibiotic kills pathogens without detectable resistance
-
Ling, L. L.; Schneider, T.; Peoples, A. J.; Spoering, A. L.; Engels, I.; Conlon, B. P.; Mueller, A.; Schaberle, T. F.; Hughes, D. E.; Epstein, S.; Jones, M.; Lazarides, L.; Steadman, V. A.; Cohen, D. R.; Felix, C. R.; Fetterman, K. A.; Millett, W. P.; Nitti, A. G.; Zullo, A. M.; Chen, C.; Lewis, K. “A new antibiotic kills pathogens without detectable resistance” Nature 2015, 517, 455.
-
(2015)
Nature
, vol.517
, pp. 455
-
-
Ling, L.L.1
Schneider, T.2
Peoples, A.J.3
Spoering, A.L.4
Engels, I.5
Conlon, B.P.6
Mueller, A.7
Schaberle, T.F.8
Hughes, D.E.9
Epstein, S.10
Jones, M.11
Lazarides, L.12
Steadman, V.A.13
Cohen, D.R.14
Felix, C.R.15
Fetterman, K.A.16
Millett, W.P.17
Nitti, A.G.18
Zullo, A.M.19
Chen, C.20
Lewis, K.21
more..
-
218
-
-
84862805452
-
Total Synthesis and Stereochemical Revision of Burkholdac A
-
Liu, J. Y.; Ma, X.; Liu, Y. Q.; Wang, Z.; Kwong, S. Q.; Ren, Q.; Tang, S. B.; Meng, Y.; Xu, Z. S.; Ye, T. “Total Synthesis and Stereochemical Revision of Burkholdac A” Synlett 2012, 783.
-
(2012)
Synlett
, pp. 783
-
-
Liu, J.Y.1
Ma, X.2
Liu, Y.Q.3
Wang, Z.4
Kwong, S.Q.5
Ren, Q.6
Tang, S.B.7
Meng, Y.8
Xu, Z.S.9
Ye, T.10
-
219
-
-
84055178563
-
Total synthesis and stereochemical assignment of burkholdac B, a depsipeptide HDAC inhibitor
-
Benelkebir, H.; Donlevy, A. M.; Packham, G.; Ganesan, A. “Total synthesis and stereochemical assignment of burkholdac B, a depsipeptide HDAC inhibitor” Org. Lett. 2011, 13, 6334.
-
(2011)
Org. Lett
, vol.13
, pp. 6334
-
-
Benelkebir, H.1
Donlevy, A.M.2
Packham, G.3
Ganesan, A.4
-
220
-
-
84876916289
-
Genomics-guided discovery of thailanstatins A, B, and C as pre-mRNA splicing inhibitors and antiproliferative agents from Burkholderia thailandensis MSMB43
-
Liu, X. Y.; Biswas, S.; Berg, M. G.; Antapli, C. M.; Xie, F.; Wang, Q.; Tang, M. C.; Tang, G. L.; Zhang, L. X.; Dreyfuss, G.; Cheng, Y. Q. “Genomics-guided discovery of thailanstatins A, B, and C as pre-mRNA splicing inhibitors and antiproliferative agents from Burkholderia thailandensis MSMB43” J. Nat. Prod. 2013, 76, 685.
-
(2013)
J. Nat. Prod
, vol.76
, pp. 685
-
-
Liu, X.Y.1
Biswas, S.2
Berg, M.G.3
Antapli, C.M.4
Xie, F.5
Wang, Q.6
Tang, M.C.7
Tang, G.L.8
Zhang, L.X.9
Dreyfuss, G.10
Cheng, Y.Q.11
-
221
-
-
84913534816
-
Enediynes: Exploration of microbial genomics to discover new anticancer drug leads
-
Shen, B.; Hindra; Yan, X. H.; Huang, T. T.; Ge, H. M.; Yang, D.; Teng, Q. H.; Rudolf, J. D.; Lohman, J. R. “Enediynes: exploration of microbial genomics to discover new anticancer drug leads” Bioorg. Med. Chem. Lett. 2015, 25, 9.
-
(2015)
Bioorg. Med. Chem. Lett
, vol.25
, pp. 9
-
-
Shen, B.1
Hindra2
Yan, X.H.3
Huang, T.T.4
Ge, H.M.5
Yang, D.6
Teng, Q.H.7
Rudolf, J.D.8
Lohman, J.R.9
-
222
-
-
84865523113
-
Characterization of a silent azaphilone gene cluster from Aspergillus niger ATCC 1015 reveals a hydroxylation-mediated pyran-ring formation
-
Zabala, A. O.; Xu, W.; Chooi, Y. H.; Tang, Y. “Characterization of a silent azaphilone gene cluster from Aspergillus niger ATCC 1015 reveals a hydroxylation-mediated pyran-ring formation” Chem. Biol. 2012, 19, 1049.
-
(2012)
Chem. Biol
, vol.19
, pp. 1049
-
-
Zabala, A.O.1
Xu, W.2
Chooi, Y.H.3
Tang, Y.4
-
223
-
-
84901009939
-
Recent advances in genomebased polyketide discovery
-
Helfrich, E. J.; Reiter, S.; Piel, J. “Recent advances in genomebased polyketide discovery” Curr. Opin. Biotechnol. 2014, 29, 107.
-
(2014)
Curr. Opin. Biotechnol
, vol.29
, pp. 107
-
-
Helfrich, E.J.1
Reiter, S.2
Piel, J.3
-
224
-
-
84871826475
-
Structure and noncanonical chemistry of nonribosomal peptide biosynthetic machinery
-
Condurso, H. L.; Bruner, S. D. “Structure and noncanonical chemistry of nonribosomal peptide biosynthetic machinery” Nat. Prod. Rep. 2012, 29, 1099.
-
(2012)
Nat. Prod. Rep
, vol.29
, pp. 1099
-
-
Condurso, H.L.1
Bruner, S.D.2
-
225
-
-
9244234513
-
Biosynthesis of nonribosomal peptides
-
Finking, R.; Marahiel, M. A. “Biosynthesis of nonribosomal peptides” Annu. Rev. Biochem. 2004, 58, 453.
-
(2004)
Annu. Rev. Biochem
, vol.58
, pp. 453
-
-
Finking, R.1
Marahiel, M.A.2
-
226
-
-
84900552743
-
Assembly line polyketide synthases: Mechanistic insights and unsolved problems
-
Khosla, C.; Herschlag, D.; Cane, D. E.; Walsh, C. T. “Assembly line polyketide synthases: mechanistic insights and unsolved problems” Biochemistry 2014, 53, 2875.
-
(2014)
Biochemistry
, vol.53
, pp. 2875
-
-
Khosla, C.1
Herschlag, D.2
Cane, D.E.3
Walsh, C.T.4
-
227
-
-
0033179468
-
The specificityconferring code of adenylation domains in nonribosomal peptide synthetases
-
Stachelhaus, T.; Mootz, H. D.; Marahiel, M. A. “The specificityconferring code of adenylation domains in nonribosomal peptide synthetases” Chem. Biol. 1999, 6, 493.
-
(1999)
Chem. Biol
, vol.6
, pp. 493
-
-
Stachelhaus, T.1
Mootz, H.D.2
Marahiel, M.A.3
-
228
-
-
33646348173
-
Isolation and identification of three new 5-alkenyl- 3,3(2H)-furanones from two Streptomyces species using a genomic screening approach
-
Banskota, A. H.; McAlpine, J. B.; Sorensen, D.; Aouidate, M.; Piraee, M.; Alarco, A. M.; Omura, S.; Shiomi, K.; Farnet, C. M.; Zazopoulos, E. “Isolation and identification of three new 5-alkenyl- 3,3(2H)-furanones from two Streptomyces species using a genomic screening approach” J. Antibiot. 2006, 59, 168.
-
(2006)
J. Antibiot
, vol.59
, pp. 168
-
-
Banskota, A.H.1
McAlpine, J.B.2
Sorensen, D.3
Aouidate, M.4
Piraee, M.5
Alarco, A.M.6
Omura, S.7
Shiomi, K.8
Farnet, C.M.9
Zazopoulos, E.10
-
229
-
-
33644513422
-
The complete biosynthetic gene cluster of the 28-membered polyketide macrolactones, halstoctacosanolides, from Streptomyces halstedii HC34
-
Tohyama, S.; Kakinuma, K.; Eguchi, T. “The complete biosynthetic gene cluster of the 28-membered polyketide macrolactones, halstoctacosanolides, from Streptomyces halstedii HC34” J. Antibiot. 2006, 59, 44.
-
(2006)
J. Antibiot
, vol.59
, pp. 44
-
-
Tohyama, S.1
Kakinuma, K.2
Eguchi, T.3
-
230
-
-
38949203821
-
Exploiting the mosaic structure of trans-acyltransferase polyketide synthases for natural product discovery and pathway dissection
-
Nguyen, T.; Ishida, K.; Jenke-Kodama, H.; Dittmann, E.; Gurgui, C.; Hochmuth, T.; Taudien, S.; Platzer, M.; Hertweck, C.; Piel, J. “Exploiting the mosaic structure of trans-acyltransferase polyketide synthases for natural product discovery and pathway dissection” Nat. Biotechnol. 2008, 26, 225.
-
(2008)
Nat. Biotechnol
, vol.26
, pp. 225
-
-
Nguyen, T.1
Ishida, K.2
Jenke-Kodama, H.3
Dittmann, E.4
Gurgui, C.5
Hochmuth, T.6
Taudien, S.7
Platzer, M.8
Hertweck, C.9
Piel, J.10
-
231
-
-
84861494390
-
Assembly and absolute configuration of short-lived polyketides from Burkholderia thailandensis
-
Ishida, K.; Lincke, T.; Hertweck, C. “Assembly and absolute configuration of short-lived polyketides from Burkholderia thailandensis” Angew. Chem., Int. Ed. 2012, 51, 5470.
-
(2012)
Angew. Chem., Int. Ed
, vol.51
, pp. 5470
-
-
Ishida, K.1
Lincke, T.2
Hertweck, C.3
-
232
-
-
78650012665
-
Genome mining reveals trans-AT polyketide synthase directed antibiotic biosynthesis in the bacterial phylum Bacteroidetes
-
Teta, R.; Gurgui, M.; Helfrich, E. J. N.; Kunne, S.; Schneider, A.; Van Echten-Deckert, G.; Mangoni, A.; Piel, J. “Genome mining reveals trans-AT polyketide synthase directed antibiotic biosynthesis in the bacterial phylum Bacteroidetes” ChemBioChem 2010, 11, 2506.
-
(2010)
Chembiochem
, vol.11
, pp. 2506
-
-
Teta, R.1
Gurgui, M.2
Helfrich, E.J.N.3
Kunne, S.4
Schneider, A.5
Van Echten-Deckert, G.6
Mangoni, A.7
Piel, J.8
-
233
-
-
33846678395
-
A cryptic type I polyketide synthase (Cpk) gene cluster in Streptomyces coelicolor A3(2)
-
Pawlik, K.; Kotowska, M.; Chater, K. F.; Kuczek, K.; Takano, E. “A cryptic type I polyketide synthase (cpk) gene cluster in Streptomyces coelicolor A3(2)” Arch. Microbiol. 2007, 187, 87.
-
(2007)
Arch. Microbiol
, vol.187
, pp. 87
-
-
Pawlik, K.1
Kotowska, M.2
Chater, K.F.3
Kuczek, K.4
Takano, E.5
-
234
-
-
84864447599
-
Structure and biosynthesis of the unusual polyketide alkaloid coelimycin P1, a metabolic product of the cpk gene cluster of Streptomyces coelicolor M145
-
Gomez-Escribano, J. P.; Song, L. J.; Fox, D. J.; Yeo, V.; Bibb, M. J.; Challis, G. L. “Structure and biosynthesis of the unusual polyketide alkaloid coelimycin P1, a metabolic product of the cpk gene cluster of Streptomyces coelicolor M145” Chem. Sci. 2012, 3, 2716.
-
(2012)
Chem. Sci
, vol.3
, pp. 2716
-
-
Gomez-Escribano, J.P.1
Song, L.J.2
Fox, D.J.3
Yeo, V.4
Bibb, M.J.5
Challis, G.L.6
-
235
-
-
77954804120
-
Staphylococcus aureus nonribosomal peptide secondary metabolites regulate virulence
-
Wyatt, M. A.; Wang, W. L.; Roux, C. M.; Beasley, F. C.; Heinrichs, D. E.; Dunman, P. M.; Magarvey, N. A. “Staphylococcus aureus nonribosomal peptide secondary metabolites regulate virulence” Science 2010, 329, 294.
-
(2010)
Science
, vol.329
, pp. 294
-
-
Wyatt, M.A.1
Wang, W.L.2
Roux, C.M.3
Beasley, F.C.4
Heinrichs, D.E.5
Dunman, P.M.6
Magarvey, N.A.7
-
236
-
-
77956955447
-
A family of pyrazinone natural products from a conserved nonribosomal peptide synthetase in Staphylococcus aureus
-
Zimmermann, M.; Fischbach, M. A. “A family of pyrazinone natural products from a conserved nonribosomal peptide synthetase in Staphylococcus aureus” Chem. Biol. 2010, 17, 925.
-
(2010)
Chem. Biol
, vol.17
, pp. 925
-
-
Zimmermann, M.1
Fischbach, M.A.2
-
237
-
-
44449144438
-
Discovery of a widely distributed toxin biosynthetic gene cluster
-
Lee, S. W.; Mitchell, D. A.; Markley, A. L.; Hensler, M. E.; Gonzalez, D.; Wohlrab, A.; Dorrestein, P. C.; Nizet, V.; Dixon, J. E. “Discovery of a widely distributed toxin biosynthetic gene cluster” Proc. Natl. Acad. Sci. U.S.A. 2008, 105, 5879.
-
(2008)
Proc. Natl. Acad. Sci. U.S.A
, vol.105
, pp. 5879
-
-
Lee, S.W.1
Mitchell, D.A.2
Markley, A.L.3
Hensler, M.E.4
Gonzalez, D.5
Wohlrab, A.6
Dorrestein, P.C.7
Nizet, V.8
Dixon, J.E.9
-
238
-
-
79958830179
-
Plantazolicin A and B: Structure elucidation of ribosomally synthesized thiazole/oxazole peptides from Bacillus amyloliquefaciens FZB42
-
Kalyon, B.; Helaly, S. E.; Scholz, R.; Nachtigall, J.; Vater, J.; Borriss, R.; Sussmuth, R. D. “Plantazolicin A and B: structure elucidation of ribosomally synthesized thiazole/oxazole peptides from Bacillus amyloliquefaciens FZB42” Org. Lett. 2011, 13, 2996.
-
(2011)
Org. Lett
, vol.13
, pp. 2996
-
-
Kalyon, B.1
Helaly, S.E.2
Scholz, R.3
Nachtigall, J.4
Vater, J.5
Borriss, R.6
Sussmuth, R.D.7
-
239
-
-
84858656036
-
Structure determination and interception of biosynthetic intermediates for the plantazolicin class of highly discriminating antibiotics
-
Molohon, K. J.; Melby, J. O.; Lee, J.; Evans, B. S.; Dunbar, K. L.; Bumpus, S. B.; Kelleher, N. L.; Mitchell, D. A. “Structure determination and interception of biosynthetic intermediates for the plantazolicin class of highly discriminating antibiotics” ACS Chem. Biol. 2011, 6, 1307.
-
(2011)
ACS Chem. Biol
, vol.6
, pp. 1307
-
-
Molohon, K.J.1
Melby, J.O.2
Lee, J.3
Evans, B.S.4
Dunbar, K.L.5
Bumpus, S.B.6
Kelleher, N.L.7
Mitchell, D.A.8
-
240
-
-
84921047423
-
Total syntheses of linear polythiazole/oxazole plantazolicin A and its biosynthetic precursor plantazolicin B
-
Wilson, Z. E.; Fenner, S.; Ley, S. V. “Total syntheses of linear polythiazole/oxazole plantazolicin A and its biosynthetic precursor plantazolicin B” Angew. Chem., Int. Ed. 2015, 54, 1284.
-
(2015)
Angew. Chem., Int. Ed
, vol.54
, pp. 1284
-
-
Wilson, Z.E.1
Fenner, S.2
Ley, S.V.3
-
241
-
-
84883218188
-
Total synthesis of the ribosomally synthesized linear azole-containing peptide plantazolicin A from Bacillus amyloliquefaciens
-
Banala, S.; Ensle, P.; Sussmuth, R. D. “Total synthesis of the ribosomally synthesized linear azole-containing peptide plantazolicin A from Bacillus amyloliquefaciens” Angew. Chem., Int. Ed. 2013, 52, 9518.
-
(2013)
Angew. Chem., Int. Ed
, vol.52
, pp. 9518
-
-
Banala, S.1
Ensle, P.2
Sussmuth, R.D.3
-
242
-
-
84861649020
-
Discovery, biosynthesis, and engineering of lantipeptides
-
Knerr, P. J.; van der Donk, W. A. “Discovery, biosynthesis, and engineering of lantipeptides” Annu. Rev. Biochem. 2012, 81, 479.
-
(2012)
Annu. Rev. Biochem
, vol.81
, pp. 479
-
-
Knerr, P.J.1
van der Donk, W.A.2
-
243
-
-
69449094338
-
Identification of a novel two-peptide lantibiotic, lichenicidin, following rational genome mining for LanM proteins
-
Begley, M.; Cotter, P. D.; Hill, C.; Ross, R. P. “Identification of a novel two-peptide lantibiotic, lichenicidin, following rational genome mining for LanM proteins” Appl. Environ. Microbiol. 2009, 75, 5451.
-
(2009)
Appl. Environ. Microbiol
, vol.75
, pp. 5451
-
-
Begley, M.1
Cotter, P.D.2
Hill, C.3
Ross, R.P.4
-
244
-
-
69449097013
-
Production of the novel two-peptide lantibiotic lichenicidin by Bacillus licheniformis DSM 13
-
Dischinger, J.; Josten, M.; Szekat, C.; Sahl, H. G.; Bierbaum, G. “Production of the novel two-peptide lantibiotic lichenicidin by Bacillus licheniformis DSM 13” PLoS One 2009, 4.
-
(2009)
Plos One
, pp. 4
-
-
Dischinger, J.1
Josten, M.2
Szekat, C.3
Sahl, H.G.4
Bierbaum, G.5
-
245
-
-
77955016145
-
Isolation, structure elucidation, and synergistic antibacterial activity of a novel two-component lantibiotic lichenicidin from Bacillus licheniformis VK21
-
Shenkarev, Z. O.; Finkina, E. I.; Nurmukhamedova, E. K.; Balandin, S. V.; Mineev, K. S.; Nadezhdin, K. D.; Yakimenko, Z. A.; Tagaev, A. A.; Temirov, Y. V.; Arseniev, A. S.; Ovchinnikova, T. V. “Isolation, structure elucidation, and synergistic antibacterial activity of a novel two-component lantibiotic lichenicidin from Bacillus licheniformis VK21” Biochemistry 2010, 49, 6462.
-
(2010)
Biochemistry
, vol.49
, pp. 6462
-
-
Shenkarev, Z.O.1
Finkina, E.I.2
Nurmukhamedova, E.K.3
Balandin, S.V.4
Mineev, K.S.5
Nadezhdin, K.D.6
Yakimenko, Z.A.7
Tagaev, A.A.8
Temirov, Y.V.9
Arseniev, A.S.10
Ovchinnikova, T.V.11
-
246
-
-
0025883573
-
Extracellular complementation of a developmental mutation implicates a small sporulation protein in aerial mycelium formation by S. Coelicolor
-
Willey, J.; Santamaria, R.; Guijarro, J.; Geistlich, M.; Losick, R. “Extracellular complementation of a developmental mutation implicates a small sporulation protein in aerial mycelium formation by S. coelicolor” Cell 1991, 65, 641.
-
(1991)
Cell
, vol.65
, pp. 641
-
-
Willey, J.1
Santamaria, R.2
Guijarro, J.3
Geistlich, M.4
Losick, R.5
-
247
-
-
0023990992
-
Promoter determining the timing and spatial localization of transcription of a cloned Streptomyces coelicolor gene encoding a spore-associated polypeptide
-
Guijarro, J.; Santamaria, R.; Schauer, A.; Losick, R. “Promoter determining the timing and spatial localization of transcription of a cloned Streptomyces coelicolor gene encoding a spore-associated polypeptide” J. Bacteriol. 1988, 170, 1895.
-
(1988)
J. Bacteriol
, vol.170
, pp. 1895
-
-
Guijarro, J.1
Santamaria, R.2
Schauer, A.3
Losick, R.4
-
248
-
-
3843091511
-
The SapB morphogen is a lantibiotic-like peptide derived from the product of the developmental gene ramS in Streptomyces coelicolor
-
Kodani, S.; Hudson, M. E.; Durrant, M. C.; Buttner, M. J.; Nodwell, J. R.; Willey, J. M. “The SapB morphogen is a lantibiotic-like peptide derived from the product of the developmental gene ramS in Streptomyces coelicolor” Proc. Natl. Acad. Sci. U.S.A. 2004, 101, 11448.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A
, vol.101
, pp. 11448
-
-
Kodani, S.1
Hudson, M.E.2
Durrant, M.C.3
Buttner, M.J.4
Nodwell, J.R.5
Willey, J.M.6
-
249
-
-
84896920111
-
Cerecidins, novel lantibiotics from Bacillus cereus with potent antimicrobial activity
-
Wang, J.; Zhang, L.; Teng, K. L.; Sun, S. T.; Sun, Z. Z.; Zhong, J. “Cerecidins, novel lantibiotics from Bacillus cereus with potent antimicrobial activity” Appl. Environ. Microbiol. 2014, 80, 2633.
-
(2014)
Appl. Environ. Microbiol
, vol.80
, pp. 2633
-
-
Wang, J.1
Zhang, L.2
Teng, K.L.3
Sun, S.T.4
Sun, Z.Z.5
Zhong, J.6
-
250
-
-
84891919526
-
Purification and characterization of antimicrobial peptides from fish isolate Carnobacterium maltaromaticum C2: Carnobacteriocin X and carnolysins A1 and A2
-
Tulini, F. L.; Lohans, C. T.; Bordon, K. C. F.; Zheng, J.; Arantes, E. C.; Vederas, J. C.; De Martinis, E. C. P. “Purification and characterization of antimicrobial peptides from fish isolate Carnobacterium maltaromaticum C2: Carnobacteriocin X and carnolysins A1 and A2” Int. J. Food Microbiol. 2014, 173, 81.
-
(2014)
Int. J. Food Microbiol
, vol.173
, pp. 81
-
-
Tulini, F.L.1
Lohans, C.T.2
Bordon, K.C.F.3
Zheng, J.4
Arantes, E.C.5
Vederas, J.C.6
de Martinis, E.7
-
251
-
-
84870694480
-
Structural characterization of the highly cyclized lantibiotic paenicidin A via a partial desulfurization/reduction strategy
-
Lohans, C. T.; Huang, Z. D.; van Belkum, M. J.; Giroud, M.; Sit, C. S.; Steels, E. M.; Zheng, J.; Whittal, R. M.; McMullen, L. M.; Vederas, J. C. “Structural characterization of the highly cyclized lantibiotic paenicidin A via a partial desulfurization/reduction strategy” J. Am. Chem. Soc. 2012, 134, 19540.
-
(2012)
J. Am. Chem. Soc
, vol.134
, pp. 19540
-
-
Lohans, C.T.1
Huang, Z.D.2
Van Belkum, M.J.3
Giroud, M.4
Sit, C.S.5
Steels, E.M.6
Zheng, J.7
Whittal, R.M.8
McMullen, L.M.9
Vederas, J.C.10
-
252
-
-
84868094646
-
Biosynthesis of the class III lantipeptide catenulipeptin
-
Wang, H.; van der Donk, W. A. “Biosynthesis of the class III lantipeptide catenulipeptin” ACS Chem. Biol. 2012, 7, 1529.
-
(2012)
ACS Chem. Biol
, vol.7
, pp. 1529
-
-
Wang, H.1
van der Donk, W.A.2
-
253
-
-
84866449155
-
Curvopeptin: A new lanthionine-containing class III lantibiotic and its co-substrate promiscuous synthetase
-
Krawczyk, B.; Voller, G. H.; Voller, J.; Ensle, P.; Sussmuth, R. D. “Curvopeptin: a new lanthionine-containing class III lantibiotic and its co-substrate promiscuous synthetase” ChemBioChem 2012, 13, 2065.
-
(2012)
Chembiochem
, vol.13
, pp. 2065
-
-
Krawczyk, B.1
Voller, G.H.2
Voller, J.3
Ensle, P.4
Sussmuth, R.D.5
-
254
-
-
84862785252
-
Gene cluster analysis for the biosynthesis of elgicins, novel lantibiotics produced by Paenibacillus elgii B69
-
Teng, Y.; Zhao, W. P.; Qian, C. D.; Li, O.; Zhu, L.; Wu, X. C. “Gene cluster analysis for the biosynthesis of elgicins, novel lantibiotics produced by Paenibacillus elgii B69” BMC Microbiol. 2012, 12.
-
(2012)
BMC Microbiol
, pp. 12
-
-
Teng, Y.1
Zhao, W.P.2
Qian, C.D.3
Li, O.4
Zhu, L.5
Wu, X.C.6
-
255
-
-
77950563372
-
Discovery of unique lanthionine synthetases reveals new mechanistic and evolutionary insights
-
Goto, Y.; Li, B.; Claesen, J.; Shi, Y. X.; Bibb, M. J.; van der Donk, W. A. “Discovery of unique lanthionine synthetases reveals new mechanistic and evolutionary insights” PLoS Biol. 2010, 8.
-
(2010)
Plos Biol
, pp. 8
-
-
Goto, Y.1
Li, B.2
Claesen, J.3
Shi, Y.X.4
Bibb, M.J.5
van der Donk, W.A.6
-
256
-
-
33846069684
-
Identification of a novel two-peptide lantibiotic, haloduracin, produced by the alkaliphile Bacillus halodurans C-125
-
Lawton, E. M.; Cotter, P. D.; Hill, C.; Ross, R. P. “Identification of a novel two-peptide lantibiotic, haloduracin, produced by the alkaliphile Bacillus halodurans C-125” FEMS Microbiol. Lett. 2007, 267, 64.
-
(2007)
FEMS Microbiol. Lett
, vol.267
, pp. 64
-
-
Lawton, E.M.1
Cotter, P.D.2
Hill, C.3
Ross, R.P.4
-
257
-
-
33751204753
-
Discovery and in vitro biosynthesis of haloduracin, a two-component lantibiotic
-
McClerren, A. L.; Cooper, L. E.; Quan, C.; Thomas, P. M.; Kelleher, N. L.; van der Donk, W. A. “Discovery and in vitro biosynthesis of haloduracin, a two-component lantibiotic” Proc. Natl. Acad. Sci. U.S.A. 2006, 103, 17243.
-
(2006)
Proc. Natl. Acad. Sci. U.S.A
, vol.103
, pp. 17243
-
-
McClerren, A.L.1
Cooper, L.E.2
Quan, C.3
Thomas, P.M.4
Kelleher, N.L.5
van der Donk, W.A.6
-
258
-
-
84855753849
-
Salivaricin D, a novel intrinsically trypsin-resistant lantibiotic from Streptococcus salivarius 5M6c isolated from a healthy infant
-
Birri, D. J.; Brede, D. A.; Nes, I. F. “Salivaricin D, a novel intrinsically trypsin-resistant lantibiotic from Streptococcus salivarius 5M6c isolated from a healthy infant” Appl. Environ. Microbiol. 2012, 78, 402.
-
(2012)
Appl. Environ. Microbiol
, vol.78
, pp. 402
-
-
Birri, D.J.1
Brede, D.A.2
Nes, I.F.3
-
259
-
-
84893100422
-
Structural characterization of thioether-bridged bacteriocins
-
Lohans, C. T.; Vederas, J. C. “Structural characterization of thioether-bridged bacteriocins” J. Antibiot. 2014, 67, 23.
-
(2014)
J. Antibiot
, vol.67
, pp. 23
-
-
Lohans, C.T.1
Vederas, J.C.2
-
260
-
-
84895873870
-
Improved lanthipeptide detection and prediction for antiSMASH
-
Blin, K.; Kazempour, D.; Wohlleben, W.; Weber, T. “Improved lanthipeptide detection and prediction for antiSMASH” PLoS One 2014, 9, e89420.
-
(2014)
Plos One
, vol.9
-
-
Blin, K.1
Kazempour, D.2
Wohlleben, W.3
Weber, T.4
-
261
-
-
33745171769
-
Structure of trichamide, a cyclic peptide from the bloom-forming cyanobacterium Trichodesmium erythraeum, predicted from the genome sequence
-
Sudek, S.; Haygood, M. G.; Youssef, D. T. A.; Schmidt, E. W. “Structure of trichamide, a cyclic peptide from the bloom-forming cyanobacterium Trichodesmium erythraeum, predicted from the genome sequence” Appl. Environ. Microbiol. 2006, 72, 4382.
-
(2006)
Appl. Environ. Microbiol
, vol.72
, pp. 4382
-
-
Sudek, S.1
Haygood, M.G.2
Youssef, D.T.A.3
Schmidt, E.W.4
-
262
-
-
40849085215
-
Microcyclamide biosynthesis in two strains of Microcystis aeruginosa: From structure to genes and vice versa
-
Ziemert, N.; Ishida, K.; Quillardet, P.; Bouchier, C.; Hertweck, C.; de Marsac, N. T.; Dittmann, E. “Microcyclamide biosynthesis in two strains of Microcystis aeruginosa: from structure to genes and vice versa” Appl. Environ. Microbiol. 2008, 74, 1791.
-
(2008)
Appl. Environ. Microbiol
, vol.74
, pp. 1791
-
-
Ziemert, N.1
Ishida, K.2
Quillardet, P.3
Bouchier, C.4
Hertweck, C.5
de Marsac, N.T.6
Dittmann, E.7
-
263
-
-
75749087607
-
Highly diverse cyanobactins in strains of the genus Anabaena
-
Leikoski, N.; Fewer, D. P.; Jokela, J.; Wahlsten, M.; Rouhiainen, L.; Sivonen, K. “Highly diverse cyanobactins in strains of the genus Anabaena” Appl. Environ. Microbiol. 2010, 76, 701.
-
(2010)
Appl. Environ. Microbiol
, vol.76
, pp. 701
-
-
Leikoski, N.1
Fewer, D.P.2
Jokela, J.3
Wahlsten, M.4
Rouhiainen, L.5
Sivonen, K.6
-
264
-
-
39149141320
-
The alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicity
-
Herrmann, A.; Burman, R.; Mylne, J. S.; Karlsson, G.; Gullbo, J.; Craik, D. J.; Clark, R. J.; Goransson, U. “The alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicity” Phytochemistry 2008, 69, 939.
-
(2008)
Phytochemistry
, vol.69
, pp. 939
-
-
Herrmann, A.1
Burman, R.2
Mylne, J.S.3
Karlsson, G.4
Gullbo, J.5
Craik, D.J.6
Clark, R.J.7
Goransson, U.8
-
265
-
-
84906704036
-
Characterization of caulonodin lasso peptides revealed unprecedented N-terminal residues and a precursor motif essential for peptide maturation
-
Zimmermann, M.; Hegemann, J. D.; Xie, X.; Marahiel, M. A. “Characterization of caulonodin lasso peptides revealed unprecedented N-terminal residues and a precursor motif essential for peptide maturation” Chem. Sci. 2014, 5, 4032.
-
(2014)
Chem. Sci
, vol.5
, pp. 4032
-
-
Zimmermann, M.1
Hegemann, J.D.2
Xie, X.3
Marahiel, M.A.4
-
266
-
-
84866533015
-
Precursor-centric genome-mining approach for lasso peptide discovery
-
Maksimov, M. O.; Pelczer, I.; Link, A. J. “Precursor-centric genome-mining approach for lasso peptide discovery” Proc. Natl. Acad. Sci. U.S.A. 2012, 109, 15223.
-
(2012)
Proc. Natl. Acad. Sci. U.S.A
, vol.109
, pp. 15223
-
-
Maksimov, M.O.1
Pelczer, I.2
Link, A.J.3
-
267
-
-
84893838456
-
Xanthomonins I-III: A new class of lasso peptides with a seven-residue macrolactam ring
-
Hegemann, J. D.; Zimmermann, M.; Zhu, S. Z.; Steuber, H.; Harms, K.; Xie, X. L.; Marahiel, M. A. “Xanthomonins I-III: a new class of lasso peptides with a seven-residue macrolactam ring” Angew. Chem., Int. Ed. 2014, 53, 2230.
-
(2014)
Angew. Chem., Int. Ed
, vol.53
, pp. 2230
-
-
Hegemann, J.D.1
Zimmermann, M.2
Zhu, S.Z.3
Steuber, H.4
Harms, K.5
Xie, X.L.6
Marahiel, M.A.7
-
268
-
-
84872103697
-
Caulosegnins I-III: A highly diverse group of lasso peptides derived from a single biosynthetic gene cluster
-
Hegemann, J. D.; Zimmermann, M.; Xie, X. L.; Marahiel, M. A. “Caulosegnins I-III: A highly diverse group of lasso peptides derived from a single biosynthetic gene cluster” J. Am. Chem. Soc. 2013, 135, 210.
-
(2013)
J. Am. Chem. Soc
, vol.135
, pp. 210
-
-
Hegemann, J.D.1
Zimmermann, M.2
Xie, X.L.3
Marahiel, M.A.4
-
269
-
-
80053350862
-
The antibacterial threaded-lasso peptide capistruin inhibits bacterial RNA polymerase
-
Kuznedelov, K.; Semenova, E.; Knappe, T. A.; Mukhamedyarov, D.; Srivastava, A.; Chatterjee, S.; Ebright, R. H.; Marahiel, M. A.; Severinov, K. “The antibacterial threaded-lasso peptide capistruin inhibits bacterial RNA polymerase” J. Mol. Biol. 2011, 412, 842.
-
(2011)
J. Mol. Biol
, vol.412
, pp. 842
-
-
Kuznedelov, K.1
Semenova, E.2
Knappe, T.A.3
Mukhamedyarov, D.4
Srivastava, A.5
Chatterjee, S.6
Ebright, R.H.7
Marahiel, M.A.8
Severinov, K.9
-
270
-
-
84979862160
-
Lasso peptides from proteobacteria: Genome mining employing heterologous expression and mass spectrometry
-
Hegemann, J. D.; Zimmermann, M.; Zhu, S. Z.; Klug, D.; Marahiel, M. A. “Lasso peptides from proteobacteria: genome mining employing heterologous expression and mass spectrometry” Biopolymers 2013, 100, 527.
-
(2013)
Biopolymers
, vol.100
, pp. 527
-
-
Hegemann, J.D.1
Zimmermann, M.2
Zhu, S.Z.3
Klug, D.4
Marahiel, M.A.5
-
271
-
-
84899576523
-
Lassomycin, a ribosomally synthesized cyclic peptide, kills Mycobacterium tuberculosis by targeting the ATP-dependent protease ClpC1P1P2
-
Gavrish, E.; Sit, C. S.; Cao, S.; Kandror, O.; Spoering, A.; Peoples, A.; Ling, L.; Fetterman, A.; Hughes, D.; Bissell, A.; Torrey, H.; Akopian, T.; Mueller, A.; Epstein, S.; Goldberg, A.; Clardy, J.; Lewis, K. “Lassomycin, a ribosomally synthesized cyclic peptide, kills Mycobacterium tuberculosis by targeting the ATP-dependent protease ClpC1P1P2” Chem. Biol. 2014, 21, 509.
-
(2014)
Chem. Biol
, vol.21
, pp. 509
-
-
Gavrish, E.1
Sit, C.S.2
Cao, S.3
Kandror, O.4
Spoering, A.5
Peoples, A.6
Ling, L.7
Fetterman, A.8
Hughes, D.9
Bissell, A.10
Torrey, H.11
Akopian, T.12
Mueller, A.13
Epstein, S.14
Goldberg, A.15
Clardy, J.16
Lewis, K.17
-
272
-
-
84919683283
-
A systematic computational analysis of biosynthetic gene cluster evolution: Lessons for engineering biosynthesis
-
Medema, M. H.; Cimermancic, P.; Sali, A.; Takano, E.; Fischbach, M. A. “A systematic computational analysis of biosynthetic gene cluster evolution: lessons for engineering biosynthesis” PLoS Comput. Biol. 2014, 10, e1004016.
-
(2014)
Plos Comput. Biol
, vol.10
-
-
Medema, M.H.1
Cimermancic, P.2
Sali, A.3
Takano, E.4
Fischbach, M.A.5
-
273
-
-
84914145236
-
4- Methylproline guided natural product discovery: Co-occurrence of 4-hydroxy- and 4-methylprolines in nostoweipeptins and nostopeptolides
-
Liu, L. W.; Jokela, J.; Herfindal, L.; Wahlsten, M.; Sinkkonen, J.; Permi, P.; Fewer, D. P.; Doskeland, S. O.; Sivonen, K. “4- Methylproline guided natural product discovery: co-occurrence of 4-hydroxy- and 4-methylprolines in nostoweipeptins and nostopeptolides” ACS Chem. Biol. 2014, 9, 2646.
-
(2014)
ACS Chem. Biol
, vol.9
, pp. 2646
-
-
Liu, L.W.1
Jokela, J.2
Herfindal, L.3
Wahlsten, M.4
Sinkkonen, J.5
Permi, P.6
Fewer, D.P.7
Doskeland, S.O.8
Sivonen, K.9
-
274
-
-
33846294440
-
The genomisotopic approach: A systematic method to isolate products of orphan biosynthetic gene clusters
-
Gross, H.; Stockwell, V. O.; Henkels, M. D.; Nowak-Thompson, B.; Loper, J. E.; Gerwick, W. H. “The genomisotopic approach: A systematic method to isolate products of orphan biosynthetic gene clusters” Chem. Biol. 2007, 14, 53.
-
(2007)
Chem. Biol
, vol.14
, pp. 53
-
-
Gross, H.1
Stockwell, V.O.2
Henkels, M.D.3
Nowak-Thompson, B.4
Loper, J.E.5
Gerwick, W.H.6
-
275
-
-
0035478654
-
Tailoring enzymes that modify nonribosomal peptides during and after chain elongation on NRPS assembly lines
-
Walsh, C. T.; Chen, H.; Keating, T. A.; Hubbard, B. K.; Losey, H. C.; Luo, L.; Marshall, C. G.; Miller, D. A.; Patel, H. M. “Tailoring enzymes that modify nonribosomal peptides during and after chain elongation on NRPS assembly lines” Curr. Opin. Chem. Biol. 2001, 5, 525.
-
(2001)
Curr. Opin. Chem. Biol
, vol.5
, pp. 525
-
-
Walsh, C.T.1
Chen, H.2
Keating, T.A.3
Hubbard, B.K.4
Losey, H.C.5
Luo, L.6
Marshall, C.G.7
Miller, D.A.8
Patel, H.M.9
-
276
-
-
85027943237
-
Metagenome mining reveals polytheonamides as posttranslationally modified ribosomal peptides
-
Freeman, M. F.; Gurgui, C.; Helf, M. J.; Morinaka, B. I.; Uria, A. R.; Oldham, N. J.; Sahl, H. G.; Matsunaga, S.; Piel, J. “Metagenome mining reveals polytheonamides as posttranslationally modified ribosomal peptides” Science 2012, 338, 387.
-
(2012)
Science
, vol.338
, pp. 387
-
-
Freeman, M.F.1
Gurgui, C.2
Helf, M.J.3
Morinaka, B.I.4
Uria, A.R.5
Oldham, N.J.6
Sahl, H.G.7
Matsunaga, S.8
Piel, J.9
-
277
-
-
84907487614
-
Characterization of a radical S-adenosyl-L-methionine epimerase, NeoN, in the last step of neomycin B biosynthesis
-
Kudo, F.; Hoshi, S.; Kawashima, T.; Kamachi, T.; Eguchi, T. “Characterization of a radical S-adenosyl-L-methionine epimerase, NeoN, in the last step of neomycin B biosynthesis” J. Am. Chem. Soc. 2014, 136, 13909.
-
(2014)
J. Am. Chem. Soc
, vol.136
, pp. 13909
-
-
Kudo, F.1
Hoshi, S.2
Kawashima, T.3
Kamachi, T.4
Eguchi, T.5
-
278
-
-
84877048798
-
Configurational assignment of secondary hydroxyl groups and methyl branches in polyketide natural products through bioinformatic analysis of the ketoreductase domain
-
Kitsche, A.; Kalesse, M. “Configurational assignment of secondary hydroxyl groups and methyl branches in polyketide natural products through bioinformatic analysis of the ketoreductase domain” ChemBioChem 2013, 14, 851.
-
(2013)
Chembiochem
, vol.14
, pp. 851
-
-
Kitsche, A.1
Kalesse, M.2
-
279
-
-
77955573389
-
Production of a new thiopeptide antibiotic, TP-1161, by a marine Nocardiopsis species
-
Engelhardt, K.; Degnes, K. F.; Kemmler, M.; Bredholt, H.; Fjaervik, E.; Klinkenberg, G.; Sletta, H.; Ellingsen, T. E.; Zotchev, S. B. “Production of a new thiopeptide antibiotic, TP-1161, by a marine Nocardiopsis species” Appl. Environ. Microbiol. 2010, 76, 4969.
-
(2010)
Appl. Environ. Microbiol
, vol.76
, pp. 4969
-
-
Engelhardt, K.1
Degnes, K.F.2
Kemmler, M.3
Bredholt, H.4
Fjaervik, E.5
Klinkenberg, G.6
Sletta, H.7
Ellingsen, T.E.8
Zotchev, S.B.9
-
280
-
-
78149447364
-
Isolation and characterization of the gene cluster for biosynthesis of the thiopeptide antibiotic TP-1161
-
Engelhardt, K.; Degnes, K. F.; Zotchev, S. B. “Isolation and characterization of the gene cluster for biosynthesis of the thiopeptide antibiotic TP-1161” Appl. Environ. Microbiol. 2010, 76, 7093.
-
(2010)
Appl. Environ. Microbiol
, vol.76
, pp. 7093
-
-
Engelhardt, K.1
Degnes, K.F.2
Zotchev, S.B.3
-
281
-
-
82555194057
-
Use of Marfey’s reagent and analogs for chiral amino acid analysis: Assessment and applications to natural products and biological systems
-
Bhushan, R.; Bruckner, H. “Use of Marfey’s reagent and analogs for chiral amino acid analysis: assessment and applications to natural products and biological systems” J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2011, 879, 3148.
-
(2011)
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci
, vol.879
, pp. 3148
-
-
Bhushan, R.1
Bruckner, H.2
-
282
-
-
85027934842
-
Paenilarvins: Iturin family lipopeptides from the honey bee pathogen Paenibacillus larvae
-
Sood, S.; Steinmetz, H.; Beims, H.; Mohr, K. I.; Stadler, M.; Djukic, M.; von der Ohe, W.; Steinert, M.; Daniel, R.; Muller, R. “Paenilarvins: iturin family lipopeptides from the honey bee pathogen Paenibacillus larvae” ChemBioChem 2014, 15, 1947.
-
(2014)
Chembiochem
, vol.15
, pp. 1947
-
-
Sood, S.1
Steinmetz, H.2
Beims, H.3
Mohr, K.I.4
Stadler, M.5
Djukic, M.6
Von Der Ohe, W.7
Steinert, M.8
Daniel, R.9
Muller, R.10
-
283
-
-
77049112553
-
Biosynthesis of the putative siderophore erythrochelin requires unprecedented crosstalk between separate nonribosomal peptide gene clusters
-
Lazos, O.; Tosin, M.; Slusarczyk, A. L.; Boakes, S.; Cortes, J.; Sidebottom, P. J.; Leadlay, P. F. “Biosynthesis of the putative siderophore erythrochelin requires unprecedented crosstalk between separate nonribosomal peptide gene clusters” Chem. Biol. 2010, 17, 160.
-
(2010)
Chem. Biol
, vol.17
, pp. 160
-
-
Lazos, O.1
Tosin, M.2
Slusarczyk, A.L.3
Boakes, S.4
Cortes, J.5
Sidebottom, P.J.6
Leadlay, P.F.7
-
284
-
-
75149116642
-
Erythrochelin - a hydroxamate-type siderophore predicted from the genome of Saccharopolyspora erythraea
-
Robbel, L.; Knappe, T. A.; Linne, U.; Xie, X. L.; Marahiel, M. A. “Erythrochelin - a hydroxamate-type siderophore predicted from the genome of Saccharopolyspora erythraea” FEBS J. 2010, 277, 663.
-
(2010)
FEBS J
, vol.277
, pp. 663
-
-
Robbel, L.1
Knappe, T.A.2
Linne, U.3
Xie, X.L.4
Marahiel, M.A.5
-
285
-
-
84906353352
-
Prediction of monomer isomery in Florine: A workflow dedicated to nonribosomal peptide discovery
-
Caradec, T.; Pupin, M.; Vanvlassenbroeck, A.; Devignes, M. D.; Smail-Tabbone, M.; Jacques, P.; Leclere, V. “Prediction of monomer isomery in Florine: a workflow dedicated to nonribosomal peptide discovery” PLoS One 2014, 9.
-
(2014)
Plos One
, pp. 9
-
-
Caradec, T.1
Pupin, M.2
Vanvlassenbroeck, A.3
Devignes, M.D.4
Smail-Tabbone, M.5
Jacques, P.6
Leclere, V.7
-
286
-
-
34548496029
-
Identification of a biosynthetic gene cluster and the six associated lipopeptides involved in swarming motility of Pseudomonas syringae pv. Tomato DC3000
-
Berti, A. D.; Greve, N. J.; Christensen, Q. H.; Thomas, M. G. “Identification of a biosynthetic gene cluster and the six associated lipopeptides involved in swarming motility of Pseudomonas syringae pv. tomato DC3000” J. Bacteriol. 2007, 189, 6312.
-
(2007)
J. Bacteriol
, vol.189
, pp. 6312
-
-
Berti, A.D.1
Greve, N.J.2
Christensen, Q.H.3
Thomas, M.G.4
-
287
-
-
56049119642
-
Prediction and manipulation of the stereochemistry of enoylreduction in modular polyketide synthases
-
Kwan, D. H.; Sun, Y. H.; Schulz, F.; Hong, H.; Popovic, B.; Sim- Stark, J. C. C.; Haydock, S. F.; Leadlay, P. F. “Prediction and manipulation of the stereochemistry of enoylreduction in modular polyketide synthases” Chem. Biol. 2008, 15, 1231.
-
(2008)
Chem. Biol
, vol.15
, pp. 1231
-
-
Kwan, D.H.1
Sun, Y.H.2
Schulz, F.3
Hong, H.4
Popovic, B.5
Sim- Stark, J.C.C.6
Haydock, S.F.7
Leadlay, P.F.8
-
288
-
-
0035951074
-
Alteration of the substrate specificity of a modular polyketide synthase acyltransferase domain through site-specific mutations
-
Reeves, C. D.; Murli, S.; Ashley, G. W.; Piagentini, M.; Hutchinson, C. R.; McDaniel, R. “Alteration of the substrate specificity of a modular polyketide synthase acyltransferase domain through site-specific mutations” Biochemistry 2001, 40, 15464.
-
(2001)
Biochemistry
, vol.40
, pp. 15464
-
-
Reeves, C.D.1
Murli, S.2
Ashley, G.W.3
Piagentini, M.4
Hutchinson, C.R.5
McDaniel, R.6
-
289
-
-
0037435603
-
A model of structure and catalysis for ketoreductase domains in modular polyketide synthases
-
Reid, R.; Piagentini, M.; Rodriguez, E.; Ashley, G.; Viswanathan, N.; Carney, J.; Santi, D. V.; Hutchinson, C. R.; McDaniel, R. “A model of structure and catalysis for ketoreductase domains in modular polyketide synthases” Biochemistry 2003, 42, 72.
-
(2003)
Biochemistry
, vol.42
, pp. 72
-
-
Reid, R.1
Piagentini, M.2
Rodriguez, E.3
Ashley, G.4
Viswanathan, N.5
Carney, J.6
Santi, D.V.7
Hutchinson, C.R.8
McDaniel, R.9
-
290
-
-
0042307438
-
Conserved amino acid residues correlating with ketoreductase stereospecificity in modular polyketide synthases
-
Caffrey, P. “Conserved amino acid residues correlating with ketoreductase stereospecificity in modular polyketide synthases” ChemBioChem 2003, 4, 654.
-
(2003)
Chembiochem
, vol.4
, pp. 654
-
-
Caffrey, P.1
-
291
-
-
0028841535
-
Divergent sequence motifs correlated with the substrate specificity of (Methyl)malonyl-CoA:Acyl carrier protein transacylase domains in modular polyketide synthases
-
Haydock, S. F.; Aparicio, J. F.; Molnar, I.; Schwecke, T.; Khaw, L. E.; Konig, A.; Marsden, A. F.; Galloway, I. S.; Staunton, J.; Leadlay, P. F. “Divergent sequence motifs correlated with the substrate specificity of (methyl)malonyl-CoA:acyl carrier protein transacylase domains in modular polyketide synthases” FEBS Lett. 1995, 374, 246.
-
(1995)
FEBS Lett
, vol.374
, pp. 246
-
-
Haydock, S.F.1
Aparicio, J.F.2
Molnar, I.3
Schwecke, T.4
Khaw, L.E.5
Konig, A.6
Marsden, A.F.7
Galloway, I.S.8
Staunton, J.9
Leadlay, P.F.10
-
292
-
-
34447294842
-
Chivosazole A - elucidation of the absolute and relative configuration
-
Janssen, D.; Albert, D.; Jansen, R.; Muller, R.; Kalesse, M. “Chivosazole A - elucidation of the absolute and relative configuration” Angew. Chem., Int. Ed. 2007, 46, 4898.
-
(2007)
Angew. Chem., Int. Ed
, vol.46
, pp. 4898
-
-
Janssen, D.1
Albert, D.2
Jansen, R.3
Muller, R.4
Kalesse, M.5
-
293
-
-
41049118134
-
Stereochemical determination of thuggacins A-C, highly active antibiotics from the myxobacterium Sorangium cellulosum
-
Bock, M.; Buntin, K.; Muller, R.; Kirschning, A. “Stereochemical determination of thuggacins A-C, highly active antibiotics from the myxobacterium Sorangium cellulosum” Angew. Chem., Int. Ed. 2008, 47, 2308.
-
(2008)
Angew. Chem., Int. Ed
, vol.47
, pp. 2308
-
-
Bock, M.1
Buntin, K.2
Muller, R.3
Kirschning, A.4
-
294
-
-
54849419509
-
Stereochemical determination and complex biosynthetic assembly of etnangien, a highly potent RNA polymerase inhibitor from the myxobacterium Sorangium cellulosum
-
Menche, D.; Arikan, F.; Perlova, O.; Horstmann, N.; Ahlbrecht, W.; Wenzel, S. C.; Jansen, R.; Irschik, H.; Muller, R. “Stereochemical determination and complex biosynthetic assembly of etnangien, a highly potent RNA polymerase inhibitor from the myxobacterium Sorangium cellulosum” J. Am. Chem. Soc. 2008, 130, 14234.
-
(2008)
J. Am. Chem. Soc
, vol.130
, pp. 14234
-
-
Menche, D.1
Arikan, F.2
Perlova, O.3
Horstmann, N.4
Ahlbrecht, W.5
Wenzel, S.C.6
Jansen, R.7
Irschik, H.8
Muller, R.9
-
295
-
-
84870351751
-
Full stereochemical determination of ajudazols A and B by bioinformatics gene cluster analysis and total synthesis of ajudazol B by an asymmetric ortholithiation strategy
-
Essig, S.; Bretzke, S.; Muller, R.; Menche, D. “Full stereochemical determination of ajudazols A and B by bioinformatics gene cluster analysis and total synthesis of ajudazol B by an asymmetric ortholithiation strategy” J. Am. Chem. Soc. 2012, 134, 19362.
-
(2012)
J. Am. Chem. Soc
, vol.134
, pp. 19362
-
-
Essig, S.1
Bretzke, S.2
Muller, R.3
Menche, D.4
-
296
-
-
84915747807
-
Disciformycins A and B: 12-membered macrolide glycoside antibiotics from the myxobacterium Pyxidicoccus fallax active against multiresistant Staphylococci
-
Surup, F.; Viehrig, K.; Mohr, K. I.; Herrmann, J.; Jansen, R.; Muller, R. “Disciformycins A and B: 12-membered macrolide glycoside antibiotics from the myxobacterium Pyxidicoccus fallax active against multiresistant Staphylococci” Angew. Chem., Int. Ed. 2014, 53, 13588.
-
(2014)
Angew. Chem., Int. Ed
, vol.53
, pp. 13588
-
-
Surup, F.1
Viehrig, K.2
Mohr, K.I.3
Herrmann, J.4
Jansen, R.5
Muller, R.6
-
297
-
-
84903791356
-
The structure elucidation and total synthesis of β-lipomycin
-
Hartmann, O.; Kalesse, M. “The structure elucidation and total synthesis of β-lipomycin” Angew. Chem., Int. Ed. 2014, 53, 7335.
-
(2014)
Angew. Chem., Int. Ed
, vol.53
, pp. 7335
-
-
Hartmann, O.1
Kalesse, M.2
-
298
-
-
39149132471
-
Nonribosomal biosynthesis of fusaricidins by Paenibacillus polymyxa PKB1 involves direct activation of a Damino acid
-
Li, J.; Jensen, S. E. “Nonribosomal biosynthesis of fusaricidins by Paenibacillus polymyxa PKB1 involves direct activation of a Damino acid” Chem. Biol. 2008, 15, 118.
-
(2008)
Chem. Biol
, vol.15
, pp. 118
-
-
Li, J.1
Jensen, S.E.2
-
299
-
-
79951534830
-
Stereochemical elucidation of streptorubin B
-
Haynes, S. W.; Sydor, P. K.; Corre, C.; Song, L. J.; Challis, G. L. “Stereochemical elucidation of streptorubin B” J. Am. Chem. Soc. 2011, 133, 1793.
-
(2011)
J. Am. Chem. Soc
, vol.133
, pp. 1793
-
-
Haynes, S.W.1
Sydor, P.K.2
Corre, C.3
Song, L.J.4
Challis, G.L.5
-
300
-
-
84898538588
-
Rapid determination of the amino acid configuration of xenotetrapeptide
-
Kegler, C.; Nollmann, F. I.; Ahrendt, T.; Fleischhacker, F.; Bode, E.; Bode, H. B. “Rapid determination of the amino acid configuration of xenotetrapeptide” ChemBioChem 2014, 15, 826.
-
(2014)
Chembiochem
, vol.15
, pp. 826
-
-
Kegler, C.1
Nollmann, F.I.2
Ahrendt, T.3
Fleischhacker, F.4
Bode, E.5
Bode, H.B.6
-
301
-
-
84986674937
-
Antibiotics from gliding bacteria . 55. Myxochromide A - a highly unsaturated lipopeptide from Myxococcus virescens
-
Trowitzsch-Kienast, W.; Gerth, K.; Wray, V.; Reichenbach, H.; Hofle, G. “Antibiotics from gliding bacteria . 55. Myxochromide A - a highly unsaturated lipopeptide from Myxococcus virescens” Liebigs Ann. Chem. 1993, 1233.
-
(1993)
Liebigs Ann. Chem
, pp. 1233
-
-
Trowitzsch-Kienast, W.1
Gerth, K.2
Wray, V.3
Reichenbach, H.4
Hofle, G.5
-
302
-
-
15744370033
-
Heterologous expression of a myxobacterial natural products assembly line in pseudomonads via red/ET recombineering
-
Wenzel, S. C.; Gross, F.; Zhang, Y.; Fu, J.; Stewart, A. F.; Muller, R. “Heterologous expression of a myxobacterial natural products assembly line in pseudomonads via red/ET recombineering” Chem. Biol. 2005, 12, 349.
-
(2005)
Chem. Biol
, vol.12
, pp. 349
-
-
Wenzel, S.C.1
Gross, F.2
Zhang, Y.3
Fu, J.4
Stewart, A.F.5
Muller, R.6
-
303
-
-
70350235608
-
Novel expression hosts for complex secondary metabolite megasynthetases: Production of myxochromide in the thermopilic isolate Corallococcus macrosporus GT-2
-
Perlova, O.; Gerth, K.; Kuhlmann, S.; Zhang, Y.; Muller, R. “Novel expression hosts for complex secondary metabolite megasynthetases: Production of myxochromide in the thermopilic isolate Corallococcus macrosporus GT-2” Microb. Cell Fact. 2009, 8, 1.
-
(2009)
Microb. Cell Fact
, vol.8
, pp. 1
-
-
Perlova, O.1
Gerth, K.2
Kuhlmann, S.3
Zhang, Y.4
Muller, R.5
-
304
-
-
33746320424
-
Nonribosomal peptide biosynthesis: Point mutations and module skipping lead to chemical diversity
-
Wenzel, S. C.; Meiser, P.; Binz, T. M.; Mahmud, T.; Muller, R. “Nonribosomal peptide biosynthesis: point mutations and module skipping lead to chemical diversity” Angew. Chem., Int. Ed. 2006, 45, 2296.
-
(2006)
Angew. Chem., Int. Ed
, vol.45
, pp. 2296
-
-
Wenzel, S.C.1
Meiser, P.2
Binz, T.M.3
Mahmud, T.4
Muller, R.5
-
305
-
-
33748254906
-
Discovery of aspoquinolones A-D, prenylated quinoline-2-one alkaloids from Aspergillus nidulans, motivated by genome mining
-
Scherlach, K.; Hertweck, C. “Discovery of aspoquinolones A-D, prenylated quinoline-2-one alkaloids from Aspergillus nidulans, motivated by genome mining” Org. Biomol. Chem. 2006, 4, 3517.
-
(2006)
Org. Biomol. Chem
, vol.4
, pp. 3517
-
-
Scherlach, K.1
Hertweck, C.2
-
306
-
-
84895076771
-
Genomics-enabled discovery of phosphonate natural products and their biosynthetic pathways
-
Ju, K. S.; Doroghazi, J. R.; Metcalf, W. W. “Genomics-enabled discovery of phosphonate natural products and their biosynthetic pathways” J. Ind. Microbiol. Biotechnol. 2014, 41, 345.
-
(2014)
J. Ind. Microbiol. Biotechnol
, vol.41
, pp. 345
-
-
Ju, K.S.1
Doroghazi, J.R.2
Metcalf, W.W.3
-
307
-
-
84896861271
-
Cyanohydrin phosphonate natural product from Streptomyces regensis
-
Cioni, J. P.; Doroghazi, J. R.; Ju, K. S.; Yu, X.; Evans, B. S.; Lee, J.; Metcalf, W. W. “Cyanohydrin phosphonate natural product from Streptomyces regensis” J. Nat. Prod. 2014, 77, 243.
-
(2014)
J. Nat. Prod
, vol.77
, pp. 243
-
-
Cioni, J.P.1
Doroghazi, J.R.2
Ju, K.S.3
Yu, X.4
Evans, B.S.5
Lee, J.6
Metcalf, W.W.7
-
308
-
-
34250818263
-
A genomic screening approach to the structure-guided identification of drug candidates from natural sources
-
Hornung, A.; Bertazzo, M.; Dziarnowski, A.; Schneider, K.; Welzel, K.; Wohlert, S. E.; Holzenkampfer, M.; Nicholson, G. J.; Bechthold, A.; Sussmuth, R. D.; Vente, A.; Pelzer, S. “A genomic screening approach to the structure-guided identification of drug candidates from natural sources” ChemBioChem 2007, 8, 757.
-
(2007)
Chembiochem
, vol.8
, pp. 757
-
-
Hornung, A.1
Bertazzo, M.2
Dziarnowski, A.3
Schneider, K.4
Welzel, K.5
Wohlert, S.E.6
Holzenkampfer, M.7
Nicholson, G.J.8
Bechthold, A.9
Sussmuth, R.D.10
Vente, A.11
Pelzer, S.12
-
309
-
-
84882447063
-
Metagenomic natural product discovery in lichen provides evidence for a family of biosynthetic pathways in diverse symbioses
-
Kampa, A.; Gagunashvili, A. N.; Gulder, T. A. M.; Morinaka, B. I.; Daolio, C.; Godejohann, M.; Miao, V. P. W.; Piel, J.; Andresson, O. S. “Metagenomic natural product discovery in lichen provides evidence for a family of biosynthetic pathways in diverse symbioses” Proc. Natl. Acad. Sci. U.S.A. 2013, 110, E3129.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A
, vol.110
-
-
Kampa, A.1
Gagunashvili, A.N.2
Gulder, T.A.M.3
Morinaka, B.I.4
Daolio, C.5
Godejohann, M.6
Miao, V.P.W.7
Piel, J.8
Andresson, O.S.9
-
310
-
-
84908333061
-
Predicting the functions and specificity of triterpenoid synthases: A mechanism-based multiintermediate docking approach
-
Tian, B. X.; Wallrapp, F. H.; Holiday, G. L.; Chow, J. Y.; Babbitt, P. C.; Poulter, C. D.; Jacobson, M. P. “Predicting the functions and specificity of triterpenoid synthases: a mechanism-based multiintermediate docking approach” PLoS Comput. Biol. 2014, 10, e1003874.
-
(2014)
Plos Comput. Biol
, vol.10
-
-
Tian, B.X.1
Wallrapp, F.H.2
Holiday, G.L.3
Chow, J.Y.4
Babbitt, P.C.5
Poulter, C.D.6
Jacobson, M.P.7
-
311
-
-
30544434099
-
Fungal secondary metabolism - from biochemistry to genomics
-
Keller, N. P.; Turner, G.; Bennett, J. W. “Fungal secondary metabolism - from biochemistry to genomics” Nat. Rev. Microbiol. 2005, 3, 937.
-
(2005)
Nat. Rev. Microbiol
, vol.3
, pp. 937
-
-
Keller, N.P.1
Turner, G.2
Bennett, J.W.3
-
312
-
-
84887586519
-
Gene clustering in plant specialized metabolism
-
Nutzmann, H. W.; Osbourn, A. “Gene clustering in plant specialized metabolism” Curr. Opin. Biotechnol. 2014, 26, 91.
-
(2014)
Curr. Opin. Biotechnol
, vol.26
, pp. 91
-
-
Nutzmann, H.W.1
Osbourn, A.2
-
313
-
-
42549088178
-
Metabolic diversification--independent assembly of operon-like gene clusters in different plants
-
Field, B.; Osbourn, A. E. “Metabolic diversification--independent assembly of operon-like gene clusters in different plants” Science 2008, 320, 543.
-
(2008)
Science
, vol.320
, pp. 543
-
-
Field, B.1
Osbourn, A.E.2
-
314
-
-
84884969886
-
Natural products - modifying metabolite pathways in plants
-
Staniek, A.; Bouwmeester, H.; Fraser, P. D.; Kayser, O.; Martens, S.; Tissier, A.; van der Krol, S.; Wessjohann, L.; Warzecha, H. “Natural products - modifying metabolite pathways in plants” Biotechnol. J. 2013, 8, 1159.
-
(2013)
Biotechnol. J
, vol.8
, pp. 1159
-
-
Staniek, A.1
Bouwmeester, H.2
Fraser, P.D.3
Kayser, O.4
Martens, S.5
Tissier, A.6
van der Krol, S.7
Wessjohann, L.8
Warzecha, H.9
-
315
-
-
0027858856
-
Total synthesis of the immunosuppressive agent (-)- discodermolide
-
Nerenberg, J. B.; Hung, D. T.; Somers, P. K.; Schreiber, S. L. “Total synthesis of the immunosuppressive agent (-)- discodermolide” J. Am. Chem. Soc. 1993, 115, 12621.
-
(1993)
J. Am. Chem. Soc
, vol.115
, pp. 12621
-
-
Nerenberg, J.B.1
Hung, D.T.2
Somers, P.K.3
Schreiber, S.L.4
-
316
-
-
0019955047
-
Antineoplastic cyclic-peptides from the marine tunicate Lissoclinum patella
-
Ireland, C. M.; Durso, A. R.; Newman, R. A.; Hacker, M. P. “Antineoplastic cyclic-peptides from the marine tunicate Lissoclinum patella” J. Org. Chem. 1982, 47, 1807.
-
(1982)
J. Org. Chem
, vol.47
, pp. 1807
-
-
Ireland, C.M.1
Durso, A.R.2
Newman, R.A.3
Hacker, M.P.4
-
317
-
-
80053243567
-
Approaches to capturing and designing biologically active small molecules produced by uncultured microbes
-
Piel, J. “Approaches to capturing and designing biologically active small molecules produced by uncultured microbes” Annu. Rev. Biochem. 2011, 65, 431.
-
(2011)
Annu. Rev. Biochem
, vol.65
, pp. 431
-
-
Piel, J.1
-
318
-
-
84908079780
-
A systematic analysis of biosynthetic gene clusters in the human microbiome reveals a common family of antibiotics
-
Donia, M. S.; Cimermancic, P.; Schulze, C. J.; Wieland Brown, L. C.; Martin, J.; Mitreva, M.; Clardy, J.; Linington, R. G.; Fischbach, M. A. “A systematic analysis of biosynthetic gene clusters in the human microbiome reveals a common family of antibiotics” Cell 2014, 158, 1402.
-
(2014)
Cell
, vol.158
, pp. 1402
-
-
Donia, M.S.1
Cimermancic, P.2
Schulze, C.J.3
Wieland Brown, L.C.4
Martin, J.5
Mitreva, M.6
Clardy, J.7
Linington, R.G.8
Fischbach, M.A.9
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