Actinomycetes biosynthetic potential: How to bridge in silico and in vivo?

Journal of Industrial Microbiology and Biotechnology

Volumn 41, Issue 2, 2014, Pages 387-402

  Rebets, Yuriy ^a   Brötz, Elke ^a   Tokovenko, Bogdan ^a   Luzhetskyy, Andriy ^a  

^a SAARLAND UNIVERSITY   (Germany)

Author keywords

Actinomycetes; Cryptic gene clusters; Genome mining; Heterologous expression; Synthetic promoters

Indexed keywords

ACTINORHODINE; BICOZAMYCIN; FERRIOXAMINE; LANTIBIOTIC; SCANDIUM;

ACTINOBACTERIA; BACILLUS SUBTILIS; BACTERIAL GENETICS; BACTERIAL GENOME; BACTERIAL METABOLISM; BACTERIOPHAGE; BIOSYNTHESIS; CHEMICAL STRUCTURE; COMPUTER MODEL; DNA MICROARRAY; ESCHERICHIA COLI; GENE ACTIVATION; GENE CLUSTER; GENE EXPRESSION; GENETIC MANIPULATION; HETEROLOGOUS EXPRESSION; HOUSEKEEPING GENE; IN VIVO STUDY; NITROGEN FIXATION; NONHUMAN; PROMOTER REGION; REGULATOR GENE; REVIEW; RNA SEQUENCE; SACCHAROMYCES CEREVISIAE; SCREENING; SECONDARY METABOLISM; SILENT GENE; STREPTOMYCES COELICOLOR; STREPTOMYCES FRADIAE; STREPTOMYCES LIVIDANS; SYNTHETIC BIOLOGY; TRANSLATION INITIATION;

ACTINOBACTERIA; BIOLOGICAL PRODUCTS; BIOSYNTHETIC PATHWAYS; COMPUTER SIMULATION; GENE EXPRESSION REGULATION, BACTERIAL; GENOME, BACTERIAL; SECONDARY METABOLISM; SYNTHETIC BIOLOGY;

EID: 84893470138     PISSN: 13675435     EISSN: 14765535     Source Type: Journal    
DOI: 10.1007/s10295-013-1352-9     Document Type: Review

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