Structure, bioactivity, and resistance mechanism of streptomonomicin, an unusual lasso peptide from an understudied halophilic actinomycete

Chemistry and Biology

Volumn 22, Issue 2, 2015, Pages 241-250

  Metelev, Mikhail ^a,b   Tietz, Jonathan I ^b   Melby, Joel O ^b   Blair, Patricia M ^b   Zhu, Lingyang ^b   Livnat, Itamar ^b   Severinov, Konstantin ^a,d   Mitchell, Douglas A ^b,c  

^a PETER THE GREAT ST PETERSBURG POLYTECHNIC UNIVERSITY   (Russian Federation)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^d RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; STREPTOMONOMICIN; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; CYCLOPEPTIDE; PEPTIDE; STREPTOMONOMICIN PEPTIDE, STREPTOMONOSPORA ALBA;

ACTINOBACTERIA; AMINO ACID ANALYSIS; ANTIBACTERIAL ACTIVITY; ARTICLE; BACILLUS ANTHRACIS; BACILLUS SUBTILIS; BIOLOGICAL ACTIVITY; BIOSYNTHESIS; FIRMICUTES; HALOPHILIC BACTERIUM; HETERONUCLEAR MULTIPLE BOND CORRELATION; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; BACTERIAL GENOME; CHEMISTRY; DNA SEQUENCE; DRUG EFFECTS; GENETICS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; MATRIX-ASSISTED LASER DESORPTION-IONIZATION MASS SPECTROMETRY; METABOLISM; MICROBIAL SENSITIVITY TEST; MULTIGENE FAMILY; PROTEIN TERTIARY STRUCTURE;

BACILLUS ANTHRACIS; FIRMICUTES; STREPTOMONOSPORA; STREPTOMONOSPORA ALBA;

ACTINOBACTERIA; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; GENOME, BACTERIAL; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; MAGNETIC RESONANCE SPECTROSCOPY; MICROBIAL SENSITIVITY TESTS; MULTIGENE FAMILY; PEPTIDES; PEPTIDES, CYCLIC; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ANALYSIS, DNA; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 84923210977     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2014.11.017     Document Type: Article

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