Tailoring enzymes that modify nonribosomal peptides during and after chain elongation on NRPS assembly lines

Current Opinion in Chemical Biology

Volumn 5, Issue 5, 2001, Pages 525-534

  Walsh, Christopher T ^a   Chen, Huawei ^a   Keating, Thomas A ^a   Hubbard, Brian K ^a   Losey, Heather C ^a   Luo, Lusong ^a   Marshall, C Gary ^a   Miller, Deborah Ann ^a   Patel, Hiten M ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ANTIBIOTIC AGENT; BLEOMYCIN; COUMARIN; CYCLOSPORIN; CYTOCHROME P450; ENZYME; GLYCOSYLTRANSFERASE; MACROLIDE; METHYLTRANSFERASE; NIKKOMYCIN; NONRIBOSOMAL PEPTIDE SYNTHETASES; NOVOBIOCIN; RACEMASE; SUGAR; THIOESTER; UNCLASSIFIED DRUG; VANCOMYCIN;

AEROBIC METABOLISM; CHEMICAL REACTION; CROSS LINKING; CYCLIZATION; ENZYME RELEASE; ENZYME STRUCTURE; HYDROXYLATION; LYSIS; METHYLATION; NONHUMAN; PEPTIDE SYNTHESIS; PROTEIN MODIFICATION; REACTION ANALYSIS; REGULATORY MECHANISM; REVIEW;

EID: 0035478654     PISSN: 13675931     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1367-5931(00)00235-0     Document Type: Review

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