A genomics-guided approach for discovering and expressing cryptic metabolic pathways

Nature Biotechnology

Volumn 21, Issue 2, 2003, Pages 187-190

  Zazopoulos, Emmanuel ^a   Huang, Kexue ^a   Staffa, Alfredo ^a   Liu, Wen ^b   Bachmann, Brian O ^a   Nonaka, Koichi ^b   Ahlert, Joachim ^b   Thorson, Jon S ^b   Shen, Ben ^b   Farnet, Chris M ^a  

^a INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; BIOSYNTHESIS; CHROMOPHORES; GENES; METABOLITES;

METABOLIC PATHWAYS;

BIOTECHNOLOGY;

ALKENYLDIALKYNE DERIVATIVE; ANTINEOPLASTIC ANTIBIOTIC; NATURAL PRODUCT; POLYKETIDE SYNTHASE; UNCLASSIFIED DRUG;

ACTINOMYCES; ARTICLE; CHROMATOPHORE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG ISOLATION; DRUG MECHANISM; EXPRESSED SEQUENCE TAG; GENE CASSETTE; GENE CLUSTER; GENE EXPRESSION; GENE LOCUS; GENE SEQUENCE; GENE TECHNOLOGY; GENETIC ANALYSIS; GENETIC CODE; GENOMICS; METABOLISM; MULTIGENE FAMILY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

ACTINOBACTERIA; ALKENES; ALKYNES; CELLS, CULTURED; ENERGY METABOLISM; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, BACTERIAL; GENOME, BACTERIAL; MICROMONOSPORA; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; SPECIES SPECIFICITY; STREPTOMYCES;

ACTINOBACTERIA (CLASS); ACTINOMYCES; UNCULTURED ACTINOMYCETE;

EID: 0037318402     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/nbt784     Document Type: Article

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