Full stereochemical determination of ajudazols a and b by bioinformatics gene cluster analysis and total synthesis of ajudazol B by an asymmetric ortholithiation strategy

Journal of the American Chemical Society

Volumn 134, Issue 47, 2012, Pages 19362-19365

  Essig, Sebastian ^a   Bretzke, Sebastian ^a   Müller, Rolf ^b   Menche, Dirk ^c  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

^c UNIVERSITY OF BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHETIC GENE CLUSTER; ISOCHROMANONE; ORTHO-LITHIATION; OXAZOLES; RESPIRATORY CHAINS; STEREO-SELECTIVE; STEREOCENTERS; SUZUKI COUPLINGS; TOTAL SYNTHESIS;

BIOINFORMATICS; STEREOCHEMISTRY; STEREOSELECTIVITY;

CLUSTER ANALYSIS;

AJUDAZOL A; AJUDAZOL B; HETEROCYCLIC COMPOUND; UNCLASSIFIED DRUG;

ARTICLE; ASYMMETRIC ORTHOLITHIATION; BIOINFORMATICS; CHEMICAL ANALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; GENE CLUSTER; GENETIC ANALYSIS; PREDICTION; STEREOCHEMISTRY; SUZUKI REACTION; SYNTHESIS;

ALCOHOL OXIDOREDUCTASES; AMINO ACID SEQUENCE; COMPUTATIONAL BIOLOGY; COUMARINS; MOLECULAR STRUCTURE; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; STEREOISOMERISM;

EID: 84870351751     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja309685n     Document Type: Article

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