Metagenome mining reveals polytheonamides as posttranslationally modified ribosomal peptides

Science

Volumn 338, Issue 6105, 2012, Pages 387-390

  Freeman, Michael F ^a   Gurgui, Cristian ^a   Helf, Maximilian J ^a   Morinaka, Brandon I ^a   Uria, Agustinus R ^a   Oldham, Neil J ^b   Sahl, Hans Georg ^a   Matsunaga, Shigeki ^c   Piel, Jörn ^a,d  

^a UNIVERSITY OF BONN   (Germany)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^c UNIVERSITY OF TOKYO   (Japan)

^d ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CARBON; NONRIBOSOMAL PEPTIDE SYNTHETASE; POLYTHEONAMIDE A; POLYTHEONAMIDE B; POLYTHEONAMIDE C; POLYTHEONAMIDE D; POLYTHEONAMIDE DERIVATIVE; RIBOSOME PROTEIN; S ADENOSYLMETHIONINE; UNCLASSIFIED DRUG;

AMINO ACID; AMMONIUM COMPOUND; BIOCHEMISTRY; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC ENGINEERING; GENOME; MOLECULAR ANALYSIS; PEPTIDE; PROTEIN; RADICAL; SPONGE; TOXIN;

ARTICLE; BACTERIAL GENE; BIOENGINEERING; BIOSYNTHESIS; EPIMERIZATION; MASS SPECTROMETRY; METAGENOME; METHYLATION; PRIORITY JOURNAL; PROTEIN PROCESSING; SPONGE (PORIFERA);

EID: 85027943237     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1226121     Document Type: Article

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