Functional analysis of environmental DNA-derived type II polyketide synthases reveals structurally diverse secondary metabolites

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 31, 2011, Pages 12629-12634

  Feng, Zhiyang ^a   Kallifidas, Dimitris ^a   Brady, Sean F ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; BACTERIAL DNA; BACTERIAL ENZYME; BP 109834; KETOSYNTHASE BETA; LANDOMYCIN E; POLYKETIDE SYNTHASE; TYPE 2 POLYKETIDE SYNTHASE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; COSMID; ENTEROCOCCUS FAECALIS; ENZYME ANALYSIS; GENE CLUSTER; METAGENOMICS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SOIL; STREPTOMYCES; STREPTOMYCES ALBUS; STREPTOMYCES BINGCHENGGENSIS; VANCOMYCIN RESISTANT ENTEROCOCCUS;

AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; BACTERIA; DNA, BACTERIAL; GENE LIBRARY; GENETIC VARIATION; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; PHYLOGENY; POLYKETIDE SYNTHASES; SEQUENCE ANALYSIS, DNA; SOIL MICROBIOLOGY; STREPTOMYCES;

BACTERIA (MICROORGANISMS); ENTEROCOCCUS FAECALIS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; STREPTOMYCES ALBUS;

EID: 79961225518     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1103921108     Document Type: Article

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