Classification of the Adenylation and Acyl-Transferase Activity of NRPS and PKS Systems Using Ensembles of Substrate Specific Hidden Markov Models

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Khayatt, Barzan I ^a,e   Overmars, Lex ^a,b   Siezen, Roland J ^a,b,c,d   Francke, Christof ^a,b,c,d  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b Netherlands Bioinformatics Center   (Netherlands)

^c Kluyver Center for Genomics of Industrial Fermentation   (Netherlands)

^d TOP INSTITUTE FOOD AND NUTRITION   (Netherlands)

^e UNIVERSITY OF SULAIMANI   (Iraq)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; NONRIBOSOMAL PEPTIDE SYNTHETASE; PEPTIDE SYNTHASE;

ADENYLATION; ARTICLE; ENZYME ACTIVITY; ENZYME SPECIFICITY; HIDDEN MARKOV MODEL; INTERNET; NEIGHBOR JOINING METHOD; NONHUMAN; PREDICTION; PROTEIN DOMAIN; SEQUENCE ALIGNMENT; SUPPORT VECTOR MACHINE;

ACYLTRANSFERASES; ADENOSINE MONOPHOSPHATE; CATALYTIC DOMAIN; MARKOV CHAINS; NUCLEOTIDYLTRANSFERASES; PEPTIDE BIOSYNTHESIS, NUCLEIC ACID-INDEPENDENT; POLYKETIDE SYNTHASES; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY; SUPPORT VECTOR MACHINES;

FUNGI;

EID: 84876340080     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0062136     Document Type: Article

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