Discovery of unique lanthionine synthetases reveals new mechanistic and evolutionary insights

PLoS Biology

Volumn 8, Issue 3, 2010, Pages

  Goto, Yuki ^a   Li, Bo ^a   Claesen, Jan ^b   Shi, Yanxiang ^a   Bibb, Mervyn J ^b   van der Donk, Wilfred A ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b JOHN INNES CENTRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

LANC CYCLASE; LANTHIONINE SYNTHETASE; LANTIBIOTIC; LYASE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOSERINE; PHOSPHOTHREONINE; PROTEIN LANC; PROTEIN LANL; PROTEIN SERINE THREONINE KINASE; PROTEIN VENL; SYNTHETASE; UNCLASSIFIED DRUG; VENEZUELIN A; VENEZUELIN L; ALANINE; BACTERIAL PROTEIN; BACTERIOCIN; DRUG DERIVATIVE; ISOENZYME; LANTHIONINE; LIGASE; RNA 16S; SULFIDE;

AMINO ACID SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME PHOSPHORYLATION; ENZYME SPECIFICITY; ENZYME STRUCTURE; GENE CLUSTER; GENE EXPRESSION; GENE IDENTIFICATION; GENE SEQUENCE; IN VITRO STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; PEPTIDE ANALYSIS; PROTEIN DOMAIN; PROTEIN PROCESSING; PROTEIN PURIFICATION; SEQUENCE HOMOLOGY; STREPTOMYCES VENEZUELAE; TARGET CELL; BACTERIUM; CHEMICAL STRUCTURE; CHEMISTRY; CLASSIFICATION; ENZYMOLOGY; GENETICS; MASS SPECTROMETRY; METABOLISM; MOLECULAR EVOLUTION; MOLECULAR GENETICS; MULTIGENE FAMILY; PHYLOGENY; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; STREPTOMYCES;

STREPTOMYCES VENEZUELAE;

ALANINE; AMINO ACID SEQUENCE; BACTERIA; BACTERIAL PROTEINS; BACTERIOCINS; EVOLUTION, MOLECULAR; ISOENZYMES; LIGASES; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; MULTIGENE FAMILY; PHYLOGENY; PROTEIN CONFORMATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RNA, RIBOSOMAL, 16S; SEQUENCE ALIGNMENT; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; STREPTOMYCES; SULFIDES;

EID: 77950563372     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1000339     Document Type: Article

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