Discovery and in vitro biosynthesis of haloduracin, a two-component lantibiotic

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 46, 2006, Pages 17243-17248

  McClerren, Amanda L ^a   Cooper, Lisa E ^a   Quan, Chao ^a   Thomas, Paul P ^a   Kelleher, Neil L ^a   Van Der Donk, Wilfred A ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Antibiotic; Dehydroalanine; Lanthionine

Indexed keywords

AMINO ACID; AMINO ACID DERIVATIVE; BLOOD CLOTTING FACTOR 10A; CYSTEINE DERIVATIVE; ENZYME; HALODURACIN; HALODURACIN ALPHA; HALODURACIN BETA; LANTHIONINE; LANTIBIOTIC; METHYLLANTHIONINE; PROTEIN HALA1; PROTEIN HALA2; PROTEIN HALM1; PROTEIN HALM2; PROTEIN PRECURSOR; SERINE; SULFIDE; THREONINE; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACILLUS HALODURANS; BACTERIAL GENOME; BACTERICIDAL ACTIVITY; DRUG SYNTHESIS; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; GRAM POSITIVE BACTERIUM; HYDRATION; IN VITRO STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ENGINEERING; PROTEIN EXPRESSION; PROTEIN ISOLATION; PROTEIN MODIFICATION; PROTEIN PROCESSING; PROTEIN PURIFICATION;

ACETOACETATES; AMINO ACID SEQUENCE; BACILLUS; BACTERIAL PROTEINS; BACTERIOCINS; FACTOR XA; IODOACETAMIDE; MOLECULAR SEQUENCE DATA; PROTEIN ENGINEERING; SEQUENCE ALIGNMENT; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

BACILLUS HALODURANS C-125; BACTERIA (MICROORGANISMS); POSIBACTERIA;

EID: 33751204753     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0606088103     Document Type: Article

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