Non-viral therapeutic approaches to ocular diseases: An overview and future directions

Journal of Controlled Release

Volumn 219, Issue , 2015, Pages 471-487

  Zulliger, Rahel ^a   Conley, Shannon M ^b   Naash, Muna I ^a  

^a UNIVERSITY OF HOUSTON   (United States)

^b UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

Eye; Nanoparticles; Non viral gene therapy; Retina; Subretinal delivery

Indexed keywords

GENE EXPRESSION; GENE TRANSFER; GENES; MACHINERY; NANOPARTICLES; PATIENT TREATMENT;

EYE; GENE EXPRESSION LEVELS; NON-VIRAL DELIVERY SYSTEMS; NON-VIRAL GENE DELIVERY; NONVIRAL GENE THERAPY; RETINA; SUBRETINAL DELIVERY; THERAPEUTIC INTERVENTION;

GENE THERAPY;

LIPOPLEX; MACROGOL; NANOPARTICLE; PEPTIDE; POLYMER; POLYSACCHARIDE; PROTEIN; VIRUS VECTOR; DNA;

ARTICLE; DRUG SAFETY; DRUG UPTAKE; ENHANCER REGION; EPIGENETICS; EYE DISEASE; GENE EXPRESSION; GENETIC ENGINEERING AND GENE TECHNOLOGY; HUMAN; IMMUNE RESPONSE; INTRAOCULAR DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; INTRAVITREAL DRUG ADMINISTRATION; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NONVIRAL GENE THERAPY; PERIOCULAR DRUG ADMINISTRATION; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PHENOTYPE; POLYADENYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; RETINA DEGENERATION; SUBRETINAL DRUG ADMINISTRATION; TOPICAL DRUG ADMINISTRATION; TRANSGENE; ANIMAL; CELL NUCLEUS; EYE DISEASES; GENE THERAPY; GENE TRANSFER; METABOLISM; RETINA; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; BIOLOGICAL TRANSPORT; CELL NUCLEUS; DNA; EYE DISEASES; GENE TRANSFER TECHNIQUES; GENETIC THERAPY; HUMANS; NANOPARTICLES; RETINA;

EID: 84947268445     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.10.007     Document Type: Article

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