A novel gene therapy vector based on hyaluronic acid and solid lipid nanoparticles for ocular diseases

International Journal of Pharmaceutics

Volumn 465, Issue 1-2, 2014, Pages 413-426

  Apaolaza, Paola Stephanie ^a   Delgado, Diego ^a   Pozo Rodríguez, Ana Del ^a   Gascón, Alicia Rodríguez ^a   Solinís, M Ángeles ^a  

^a UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

Author keywords

Gene therapy; Hyaluronic acid; Protamine; Solid lipid nanoparticles; Transfection; X linked juvenile retinoschisis

Indexed keywords

AGAROSE; HERMES ANTIGEN; HYALURONIC ACID; PROTAMINE; RETINOSCHISIN; SOLID LIPID NANOPARTICLE; CD44V ANTIGEN; DNA; NANOCARRIER; PLASMID VECTOR; CD44 PROTEIN, HUMAN; ENHANCED GREEN FLUORESCENT PROTEIN; EYE PROTEIN; GREEN FLUORESCENT PROTEIN; LIPID; NANOPARTICLE; RS1 PROTEIN, HUMAN;

ANTIGEN EXPRESSION; ARTICLE; CELL CULTURE; CELL DIVISION; CELL VIABILITY; CELL VIABILITY ASSAY; CELLULAR DISTRIBUTION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; EYE DISEASE; FLOW CYTOMETRY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IN VITRO GENE TRANSFER; IN VITRO STUDY; NONVIRAL GENE THERAPY; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINOSCHISIS; ZETA POTENTIAL; ENDOCYTOSIS; GENE TARGETING; GENE VECTOR; HEK293 CELL LINE; INTERNALIZATION; MOLECULAR WEIGHT; NANOPHARMACEUTICS; NONVIRAL GENE DELIVERY SYSTEM; TARGET ORGAN; CHEMISTRY; COMPARATIVE STUDY; GENE THERAPY; GENETICS; LIPID METABOLISM; METABOLISM; PIGMENT EPITHELIUM; PROCEDURES; TIME;

ANTIGENS, CD44; ENDOCYTOSIS; EYE PROTEINS; GENETIC THERAPY; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HUMANS; HYALURONIC ACID; LIPID METABOLISM; LIPIDS; NANOPARTICLES; PARTICLE SIZE; PROTAMINES; RETINAL PIGMENT EPITHELIUM; RETINOSCHISIS; TIME FACTORS; TRANSFECTION;

EID: 84897954495     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.02.038     Document Type: Article

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