Surfactants, not size or zeta-potential influence blood-brain barrier passage of polymeric nanoparticles

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 87, Issue 1, 2014, Pages 19-29

  Voigt, Nadine ^a   Henrich Noack, Petra ^a   Kockentiedt, Sarah ^a   Hintz, Werner ^a   Tomas, Jürgen ^a   Sabel, Bernhard A ^a  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

Author keywords

Blood brain barrier; Cellular uptake of nanoparticles; In vivo imaging; Polybutylcyanoacrylate nanoparticles; Surfactants; Zeta potential

Indexed keywords

CYANOACRYLATE DERIVATIVE; IONIC SURFACTANT; NANOPARTICLE; POLY(BUTYL 2 CYANOACRYLATE); UNCLASSIFIED DRUG; DRUG CARRIER; EMULSION; POLYMER; SURFACTANT;

ANIMAL EXPERIMENT; ARTICLE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DRUG TRANSPORT; EMULSION; NANOENGINEERING; NANOMEDICINE; NEUROIMAGING; NONHUMAN; PARTICLE SIZE; POLYMERIZATION; RAT; RETINA BLOOD VESSEL; ZETA POTENTIAL; ADSORPTION; ANIMAL; BLOOD RETINA BARRIER; CHEMISTRY; CONFOCAL MICROSCOPY; DRUG EFFECTS; INBRED RAT STRAIN; INTRAVENOUS DRUG ADMINISTRATION; KINETICS; METABOLISM; SURFACE PROPERTY; TRANSPORT AT THE CELLULAR LEVEL;

ADSORPTION; ANIMALS; BIOLOGICAL TRANSPORT; BLOOD-BRAIN BARRIER; BLOOD-RETINAL BARRIER; DRUG CARRIERS; EMULSIONS; INJECTIONS, INTRAVENOUS; KINETICS; MICROSCOPY, CONFOCAL; NANOPARTICLES; NEUROIMAGING; PARTICLE SIZE; POLYMERS; RATS, INBRED STRAINS; SURFACE PROPERTIES; SURFACE-ACTIVE AGENTS;

EID: 84901601279     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2014.02.013     Document Type: Article

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