Efficient transfer of genes into murine cardiac grafts by starburst polyamidoamine dendrimers

Human Gene Therapy

Volumn 9, Issue 4, 1998, Pages 553-560

  Qin, Lihui ^a   Pahud, Dominique R ^a   Ding, Yaozhong ^a   Bielinska, Anna U ^b   Kukowska Latallo, Jolanta F ^b   Baker Jr , James R ^b   Bromberg, Jonathan S ^a,c  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE; BETA GALACTOSIDASE; DENDRIMER; INTERLEUKIN 10; MYOSIN HEAVY CHAIN; POLYAMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROL; CONTROLLED STUDY; GENE TRANSFER; GRAFT SURVIVAL; HEART GRAFT; IMMUNOSUPPRESSIVE TREATMENT; MOUSE; MUSCLE CELL; NONHUMAN; PLASMID; REPORTER GENE;

ANIMALIA; MURINAE;

EID: 0032031049     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.1998.9.4-553     Document Type: Article

References (7)

1. ACSADI, G., JIAO, S., JANI, A., DUKE, D., WILLIAMS, P., CHONG, W., and WOLFF, J.A. (1991). Direct gene transfer and expression into rat heart in vivo. Nature New Biol. 3, 71-81.
2. BACCETTA, R., BIGLER, M., TOURAINE, J.L., PARKMAN, R., TOVO, P.A., ABRAMS, J., DE WAAL MALEFYT, R., DE VRIES, J.E., and RONCAROLO, M.G. (1994). High levels of interleukin 10 production in vivo are associated with tolerance in SCID patients transplanted with HLA mismatched hematopoietic stem cells. J. Exp. Med. 179, 493-502.
3. BARTH, R.F., ADAMS, D.M., SOLOWAY, A.H., ALAM, F., and DARBY, M.V. (1994). Boronated starburst dendrimer-monoclonal antibody immunoconjugates: evaluation as a potential delivery system for neutron capture therapy. Bioconjug Chem. 5, 58-66.
4. BENGAMOUR, P.Y., MULLEN, Y., SHARED, A., BAHMILLER, D., and CSETE, M.E. (1996). Decreased alloreactivity to human islets secreting recombinant viral interleukin 10. Transplantation 62, 1306-1312.
5. BIELINSKA, A.U., KUKOWSKA-LATALLO, J.F., JOHNSON, J., TOMALIA, D.A., and BAKER, J.R. (1996). Regulation of in vitro gene expression using antisense oligonucleotides or antisense expression plasmids transfected using starburst PAMAM dendrimers. Nucleic Acids Res. 24, 2176-2182.
6. BIELINSKA, A.U., KUKOWSKA-LATALLO, J.F., and BAKER, J.R. (1997). The interaction of plasmid DNA with polyamidoamine dendrimers: mechanism of complex formation and analysis of alterations induced in nuclease sensitivity and transcriptional activity of the complexed DNA. Biochim. Biophys. Acta 1353, 180-190.
7. BRAMSON, J.L., GRAHAM, F.L., and GAULDIE, J. (1995). The use of adenoviral vectors for gene therapy and gene transfer in vivo. Curr. Opin. Biotechnol. 6, 590-595.