The role of topical antibiotic prophylaxis to prevent endophthalmitis after intravitreal injection

Ophthalmology

Volumn 121, Issue 1, 2014, Pages 283-289

  Storey, Philip ^a   Dollin, Michael ^a   Pitcher, John ^a   Reddy, Sahitya ^b   Vojtko, Joseph ^b   Vander, James ^a   Hsu, Jason ^a   Garg, Sunir J ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AFLIBERCEPT; ANTIBIOTIC AGENT; ATROPINE; BEVACIZUMAB; CEFTAZIDIME; PREDNISOLONE ACETATE; RANIBIZUMAB; TOBRAMYCIN; VANCOMYCIN;

ANTIBIOTIC PROPHYLAXIS; CASE CONTROL STUDY; CLINICAL ARTICLE; CONFERENCE PAPER; ENDOPHTHALMITIS; HUMAN; INCIDENCE; MEDICAL RECORD REVIEW; PRIORITY JOURNAL; RETROSPECTIVE STUDY; VISUAL ACUITY;

ADMINISTRATION, TOPICAL; AGED; AMIKACIN; ANGIOGENESIS INHIBITORS; ANTI-BACTERIAL AGENTS; ANTIBIOTIC PROPHYLAXIS; BACTERIA; CASE-CONTROL STUDIES; CEFTAZIDIME; ENDOPHTHALMITIS; EYE INFECTIONS, BACTERIAL; FEMALE; HUMANS; INCIDENCE; INTRAVITREAL INJECTIONS; MALE; MIDDLE AGED; OPHTHALMIC SOLUTIONS; RETINAL DISEASES; RETROSPECTIVE STUDIES; VANCOMYCIN; VISUAL ACUITY; VITREOUS BODY;

EID: 84891629069     PISSN: 01616420     EISSN: 15494713     Source Type: Journal    
DOI: 10.1016/j.ophtha.2013.08.037     Document Type: Conference Paper

References (21)

1. C.P. Shah, S.J. Garg, and J.F. Vander Post-Injection Endophthalmitis (PIE) Study Team Outcomes and risk factors associated with endophthalmitis after intravitreal injection of anti-vascular endothelial growth factor agents Ophthalmology 118 2011 2028 2034
2. J.M. Moss, S.R. Sanislo, and C.N. Ta A prospective randomized evaluation of topical gatifloxacin on conjunctival flora in patients undergoing intravitreal injections Ophthalmology 116 2009 1498 1501
3. C.N. Ta, P.R. Egbert, and K. Singh et al. Prospective randomized comparison of 3-day versus 1-hour preoperative ofloxacin prophylaxis for cataract surgery Ophthalmology 109 2002 2036 2040 discussion 2040-1
4. S.S. Bhatt, K.E. Stepien, and K. Joshi Prophylactic antibiotic use after intravitreal injection: effect on endophthalmitis rate Retina 31 2011 2032 2036
5. A.R. Bhavsar, M.S. Ip, and A.R. Glassman DRCRnet and the SCORE Study Groups The risk of endophthalmitis following intravitreal triamcinolone injection in the DRCRnet and SCORE clinical trials Am J Ophthalmol 144 2007 454 456
6. A.R. Bhavsar, J.M. Googe Jr., and C.R. Stockdale Diabetic Retinopathy Clinical Research Network Risk of endophthalmitis after intravitreal drug injection when topical antibiotics are not required: the Diabetic Retinopathy Clinical Research Network laser-ranibizumab-triamcinolone clinical trials Arch Ophthalmol 127 2009 1581 1583
7. S.J. Kim, and H.S. Toma Antimicrobial resistance and ophthalmic antibiotics: 1-year results of a longitudinal controlled study of patients undergoing intravitreal injections Arch Ophthalmol 129 2011 1180 1188
8. E. Milder, J. Vander, C. Shah, and S. Garg Changes in antibiotic resistance patterns of conjunctival flora due to repeated use of topical antibiotics after intravitreal injection Ophthalmology 119 2012 1420 1424
9. C.S. Cheung, A.W. Wong, and A. Lui et al. Incidence of endophthalmitis and use of antibiotic prophylaxis after intravitreal injections Ophthalmology 119 2012 1609 1614
10. A.E. Green-Simms, N.S. Ekdawi, and S.J. Bakri Survey of intravitreal injection techniques among retinal specialists in the United States Am J Ophthalmol 151 2011 329 332
11. Kulkarni AA, Altaweel MM, Tewari A. Comment on: Cheung CS, Wong AW, Lui A, et al. Incidence of endophthalmitis and use of antibiotic prophylaxis after intravitreal injections. Ophthalmology 2012;119:1609-14. In: American Society of Retina Specialists October Literature Roundup. April 2012. Available at: http://www.asrs.org/patients/retina-news/literature-roundup/91/ october-literature-roundup. Accessed August 18, 2013.
12. R.W. Chen, A. Rachitskaya, I.U. Scott, and H.W. Flynn Is the use of topical antibiotics for intravitreal injections the standard of care or are we better off without antibiotics? JAMA Ophthalmol 131 2013 840 842
13. C.K. Cassel, and J.A. Guest Choosing wisely: helping physicians and patients make smart decisions about their care JAMA 307 2012 1801 1802
14. D.W. Parke II, A.L. Coleman, W.L. Rich III, and F. Lum Choosing wisely: five ideas that physicians and patients can discuss Ophthalmology 120 2013 443 444
15. S.J. Kim, H.S. Toma, and N.K. Midha et al. Antibiotic Resistance of Conjunctiva and Nasopharynx Evaluation Study: a prospective study of patients undergoing intravitreal injections Ophthalmology 117 2010 2372 2378
16. D. Miller, P.M. Flynn, and I.U. Scott et al. In vitro fluoroquinolone resistance in staphylococcal endophthalmitis isolates Arch Ophthalmol 124 2006 479 483
17. V.T. Yin, D.J. Weisbrod, and K.T. Eng et al. Antibiotic resistance of ocular surface flora with repeated use of a topical antibiotic after intravitreal injection JAMA Ophthalmol 131 2013 456 461
18. D.C. Hooper Fluoroquinolone resistance among gram-positive cocci Lancet Infect Dis 2 2002 530 538
19. C.A. McCannel Meta-analysis of endophthalmitis after intravitreal injection of anti-vascular endothelial growth factor agents: causative organisms and possible prevention strategies Retina 31 2011 654 661
20. E. Chen, M.Y. Lin, J. Cox, and D.M. Brown Endophthalmitis after intravitreal injection: the importance of viridans streptococci Retina 31 2011 1525 1533
21. R.G. Abell, N.M. Kerr, P. Allen, and B.J. Vote Intravitreal injections: is there benefit for a theatre setting? Br J Ophthalmol 96 2012 1474 1478