DNA nanoparticle-mediated ABCA4 delivery rescues Stargardt dystrophy in mice

Journal of Clinical Investigation

Volumn 122, Issue 9, 2012, Pages 3221-3226

  Han, Zongchao ^a   Conley, Shannon M ^a   Makkia, Rasha S ^a   Cooper, Mark J ^b   Naash, Muna I ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b Copernicus Therapeutics Inc ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ATP BINDING CASSETTE TRANSPORTER A4; BETA ACTIN; DNA NANOPARTICLE; NANOCARRIER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA VECTOR; GENE EXPRESSION; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; PROTEIN EXPRESSION; STARGARDT DISEASE;

ANALYSIS OF VARIANCE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CORNEAL DYSTROPHIES, HEREDITARY; DNA; GENE EXPRESSION; GENETIC THERAPY; HUMANS; INJECTIONS, INTRAOCULAR; LIPOFUSCIN; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NANOPARTICLES; PHENOTYPE; RETINAL PIGMENT EPITHELIUM; TRANSGENES;

EID: 84865977758     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI64833     Document Type: Article

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