CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression

Nature Biotechnology

Volumn 26, Issue 5, 2008, Pages 549-551

  Hyde, Stephen C ^a,f   Pringle, Ian A ^a,f   Abdullah, Syahril ^a,f,g   Lawton, Anna E ^a,f   Davies, Lee A ^a,f   Varathalingam, Anusha ^a,f   Nunez Alonso, Graciela ^a,f   Green, Anne Marie ^a,f   Bazzani, Reto P ^a,f   Sumner Jones, Stephanie G ^a,f   Chan, Mario ^b,f   Li, Hongyu ^c   Yew, Nelson S ^d   Cheng, Seng H ^d   Christopher Boyd, A ^e,f   Davies, Jane C ^b,f   Griesenbach, Uta ^b,f   Porteous, David J ^e,f   Sheppard, David N ^c   Munkonge, Felix M ^b,f   Alton, Eric W F W ^b,f   Gill, Deborah R ^a,f   more..

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^c UNIVERSITY OF BRISTOL   (United Kingdom)

^d GENZYME CORPORATION   (United States)

^e UNIVERSITY OF EDINBURGH   (United Kingdom)

^f UK Cystic Fibrosis Gene Therapy Consortium ^*

^g UNIVERSITY PUTRA MALAYSIA   (Malaysia)

Author keywords

[No Author keywords available]

Indexed keywords

BIOTECHNOLOGY; GENE EXPRESSION; NUCLEOTIDES; RESPIRATORY SYSTEM; SIGNAL TRANSDUCTION;

DINUCLEOTIDES; INFLAMMATORY RESPONSE; LUNG INFLAMMATION; PLASMIDS; TRANSGENE EXPRESSION;

DNA;

CPG OLIGODEOXYNUCLEOTIDE;

ARTICLE; DRUG DELIVERY SYSTEM; EXPRESSION VECTOR; GENE EXPRESSION; IN VIVO GENE TRANSFER; INFLAMMATORY INFILTRATE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; TRANSGENE;

ANIMALS; CPG ISLANDS; GENE TARGETING; GENE THERAPY; INFLAMMATION; LUNG; PLASMIDS;

EID: 43449111490     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt1399     Document Type: Article

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