메뉴 건너뛰기




Volumn 1, Issue 1, 2006, Pages

Efficient non-viral ocular gene transfer with compacted DNA nanoparticles

Author keywords

[No Author keywords available]

Indexed keywords

DNA; NANOPARTICLE; NUCLEIC ACID; DRUG CARRIER; ENHANCED GREEN FLUORESCENT PROTEIN; GREEN FLUORESCENT PROTEIN; MESSENGER RNA; PRIMER DNA; RECOMBINANT DNA; RECOMBINANT PROTEIN;

EID: 34248570405     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0000038     Document Type: Article
Times cited : (202)

References (61)
  • 1
    • 0034118380 scopus 로고    scopus 로고
    • Missense mutations in MIP underlie autosomal dominant 'polymorphic' and lamellar cataracts linked to 12q
    • Berry V, Francis P, Kaushal S, Moore A, Bhattacharya S (2000) Missense mutations in MIP underlie autosomal dominant 'polymorphic' and lamellar cataracts linked to 12q. Nat Genet 25: 15-17.
    • (2000) Nat Genet , vol.25 , pp. 15-17
    • Berry, V.1    Francis, P.2    Kaushal, S.3    Moore, A.4    Bhattacharya, S.5
  • 3
    • 0036500230 scopus 로고    scopus 로고
    • On the genetics of retinitis pigmentosa and on mutation-independent approaches to therapeutic intervention
    • Farrar GJ, Kenna PF, Humphries P (2002) On the genetics of retinitis pigmentosa and on mutation-independent approaches to therapeutic intervention. Embo J 21: 857-864.
    • (2002) Embo J , vol.21 , pp. 857-864
    • Farrar, G.J.1    Kenna, P.F.2    Humphries, P.3
  • 4
    • 27744574620 scopus 로고    scopus 로고
    • Insights into X-linked retinitis pigmentosa type 3, allied diseases and underlying pathomechanisms
    • Ferreira PA (2005) Insights into X-linked retinitis pigmentosa type 3, allied diseases and underlying pathomechanisms. Hum Mol Genet 14 Suppl 2: R259-267.
    • (2005) Hum Mol Genet , vol.14 , Issue.SUPPL. 2
    • Ferreira, P.A.1
  • 5
    • 0032421235 scopus 로고    scopus 로고
    • Photoreceptor membrane proteins, phototransduction, and retinal degenerative diseases. The Friedenwald Lecture
    • Molday RS (1998) Photoreceptor membrane proteins, phototransduction, and retinal degenerative diseases. The Friedenwald Lecture. Invest Ophthalmol Vis Sci 39: 2491-2513.
    • (1998) Invest Ophthalmol Vis Sci , vol.39 , pp. 2491-2513
    • Molday, R.S.1
  • 6
    • 32944462134 scopus 로고    scopus 로고
    • Commentary: An aye for eye gene therapy
    • Bennett J (2006) Commentary: an aye for eye gene therapy. Hum Gene Ther 17: 177-179.
    • (2006) Hum Gene Ther , vol.17 , pp. 177-179
    • Bennett, J.1
  • 7
    • 28444452653 scopus 로고    scopus 로고
    • Pharmacological and rAAV gene therapy rescue of visual functions in a blind mouse model of Leber congenital amaurosis
    • Batten ML, Imanishi Y, Tu DC, Doan T, Zhu L, et al. (2005) Pharmacological and rAAV gene therapy rescue of visual functions in a blind mouse model of Leber congenital amaurosis. PLoS Med 2: e333.
    • (2005) PLoS Med , vol.2
    • Batten, M.L.1    Imanishi, Y.2    Tu, D.C.3    Doan, T.4    Zhu, L.5
  • 8
    • 0031965901 scopus 로고    scopus 로고
    • Ribozyme-targeted destruction of RNA associated with autosomal-dominant retinitis pigmentosa
    • Drenser KA, Timmers AM, Hauswirth WW, Lewin AS (1998) Ribozyme-targeted destruction of RNA associated with autosomal-dominant retinitis pigmentosa. Invest Ophthalmol Vis Sci 39: 681-689.
    • (1998) Invest Ophthalmol Vis Sci , vol.39 , pp. 681-689
    • Drenser, K.A.1    Timmers, A.M.2    Hauswirth, W.W.3    Lewin, A.S.4
  • 9
    • 0031880563 scopus 로고    scopus 로고
    • Ribozyme rescue of photoreceptor cells in a transgenic rat model of autosomal dominant retinitis pigmentosa
    • Lewin AS, Drenser KA, Hauswirth WW, Nishikawa S, Yasumura D, et al. (1998) Ribozyme rescue of photoreceptor cells in a transgenic rat model of autosomal dominant retinitis pigmentosa. Nat Med 4: 967-971.
    • (1998) Nat Med , vol.4 , pp. 967-971
    • Lewin, A.S.1    Drenser, K.A.2    Hauswirth, W.W.3    Nishikawa, S.4    Yasumura, D.5
  • 10
    • 0035504663 scopus 로고    scopus 로고
    • Gene replacement therapy in the retinal degeneration slow (rds) mouse: The effect on retinal degeneration following partial transduction of the retina
    • Sarra GM, Stephens C, de Alwis M, Bainbridge JW, Smith AJ, et al. (2001) Gene replacement therapy in the retinal degeneration slow (rds) mouse: the effect on retinal degeneration following partial transduction of the retina. Hum Mol Genet 10: 2353-2361.
    • (2001) Hum Mol Genet , vol.10 , pp. 2353-2361
    • Sarra, G.M.1    Stephens, C.2    de Alwis, M.3    Bainbridge, J.W.4    Smith, A.J.5
  • 11
    • 5444266028 scopus 로고    scopus 로고
    • Recombinant AAV-mediated gene transfer to the retina: Gene therapy perspectives
    • Rolling F (2004) Recombinant AAV-mediated gene transfer to the retina: gene therapy perspectives. Gene Ther 11 Suppl 1: S26-32.
    • (2004) Gene Ther , vol.11 , Issue.SUPPL. 1
    • Rolling, F.1
  • 12
    • 0029893012 scopus 로고    scopus 로고
    • Photoreceptor cell rescue in retinal degeneration (rd) mice by in vivo gene therapy
    • Bennett J, Tanabe T, Sun D, Zeng Y, Kjeldbye H, et al. (1996) Photoreceptor cell rescue in retinal degeneration (rd) mice by in vivo gene therapy. Nat Med 2: 649-654.
    • (1996) Nat Med , vol.2 , pp. 649-654
    • Bennett, J.1    Tanabe, T.2    Sun, D.3    Zeng, Y.4    Kjeldbye, H.5
  • 13
    • 33645420955 scopus 로고    scopus 로고
    • RPE65 gene delivery restores isomerohydrolase activity and prevents early cone loss in Rpe65-/- mice
    • Chen Y, Moiseyev G, Takahashi Y, Ma JX (2006) RPE65 gene delivery restores isomerohydrolase activity and prevents early cone loss in Rpe65-/- mice. Invest Ophthalmol Vis Sci 47: 1177-1184.
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 1177-1184
    • Chen, Y.1    Moiseyev, G.2    Takahashi, Y.3    Ma, J.X.4
  • 14
    • 0033947697 scopus 로고    scopus 로고
    • Restoration of photoreceptor ultrastructure and function in retinal degeneration slow mice by gene therapy
    • Ali RR, Sarra GM, Stephens C, Alwis MD, Bainbridge JW, et al. (2000) Restoration of photoreceptor ultrastructure and function in retinal degeneration slow mice by gene therapy. Nat Genet 25: 306-310.
    • (2000) Nat Genet , vol.25 , pp. 306-310
    • Ali, R.R.1    Sarra, G.M.2    Stephens, C.3    Alwis, M.D.4    Bainbridge, J.W.5
  • 15
  • 16
    • 0032582425 scopus 로고    scopus 로고
    • Congenital stationary night blindness in the dog: Common mutation in the RPE65 gene indicates founder effect
    • Aguirre GD, Baldwin V, Pearce-Kelling S, Narfstrom K, Ray K, et al. (1998) Congenital stationary night blindness in the dog: common mutation in the RPE65 gene indicates founder effect. Mol Vis 4: 23.
    • (1998) Mol Vis , vol.4 , pp. 23
    • Aguirre, G.D.1    Baldwin, V.2    Pearce-Kelling, S.3    Narfstrom, K.4    Ray, K.5
  • 18
    • 0035032662 scopus 로고    scopus 로고
    • Gene therapy restores vision in a canine model of childhood blindness
    • Acland GM, Aguirre GD, Ray J, Zhang Q, Aleman TS, et al. (2001) Gene therapy restores vision in a canine model of childhood blindness. Nat Genet 28: 92-95.
    • (2001) Nat Genet , vol.28 , pp. 92-95
    • Acland, G.M.1    Aguirre, G.D.2    Ray, J.3    Zhang, Q.4    Aleman, T.S.5
  • 19
    • 28444442243 scopus 로고    scopus 로고
    • Long-term restoration of rod and cone vision by single dose rAAV-mediated gene transfer to the retina in a canine model of childhood blindness
    • Acland GM, Aguirre GD, Bennett J, Aleman TS, Cideciyan AV, et al. (2005) Long-term restoration of rod and cone vision by single dose rAAV-mediated gene transfer to the retina in a canine model of childhood blindness. Mol Ther 12: 1072-1082.
    • (2005) Mol Ther , vol.12 , pp. 1072-1082
    • Acland, G.M.1    Aguirre, G.D.2    Bennett, J.3    Aleman, T.S.4    Cideciyan, A.V.5
  • 20
    • 33644525947 scopus 로고    scopus 로고
    • Assessment of structure and function over a 3-year period after gene transfer in RPE65-/- dogs
    • Narfstrom K, Vaegan, Katz M, Bragadottir R, Rakoczy EP, et al. (2005) Assessment of structure and function over a 3-year period after gene transfer in RPE65-/- dogs. Doc Ophthalmol 111: 39-48.
    • (2005) Doc Ophthalmol , vol.111 , pp. 39-48
    • Narfstrom, K.1    Vaegan2    Katz, M.3    Bragadottir, R.4    Rakoczy, E.P.5
  • 22
    • 0038745599 scopus 로고    scopus 로고
    • Progress and problems with the use of viral vectors for gene therapy
    • Thomas CE, Ehrhardt A, Kay MA (2003) Progress and problems with the use of viral vectors for gene therapy. Nat Rev Genet 4: 346-358.
    • (2003) Nat Rev Genet , vol.4 , pp. 346-358
    • Thomas, C.E.1    Ehrhardt, A.2    Kay, M.A.3
  • 23
    • 33645923713 scopus 로고    scopus 로고
    • Prevalence of neutralizing antibodies against adeno-associated virus (AAV) types 2, 5, and 6 in cystic fibrosis and normal populations: Implications for gene therapy using AAV vectors
    • Halbert CL, Miller AD, McNamara S, Emerson J, Gibson RL, et al. (2006) Prevalence of neutralizing antibodies against adeno-associated virus (AAV) types 2, 5, and 6 in cystic fibrosis and normal populations: Implications for gene therapy using AAV vectors. Hum Gene Ther 17: 440-447.
    • (2006) Hum Gene Ther , vol.17 , pp. 440-447
    • Halbert, C.L.1    Miller, A.D.2    McNamara, S.3    Emerson, J.4    Gibson, R.L.5
  • 24
    • 33645734405 scopus 로고    scopus 로고
    • Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1
    • Ott MG, Schmidt M, Schwarzwaelder K, Stein S, Siler U, et al. (2006) Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1. Nat Med 12: 401-409.
    • (2006) Nat Med , vol.12 , pp. 401-409
    • Ott, M.G.1    Schmidt, M.2    Schwarzwaelder, K.3    Stein, S.4    Siler, U.5
  • 25
    • 33645451483 scopus 로고    scopus 로고
    • Mutagenesis and oncogenesis by chromosomal insertion of gene transfer vectors
    • Baum C, Kustikova O, Modlich U, Li Z, Fehse B (2006) Mutagenesis and oncogenesis by chromosomal insertion of gene transfer vectors. Hum Gene Ther 17: 253-263.
    • (2006) Hum Gene Ther , vol.17 , pp. 253-263
    • Baum, C.1    Kustikova, O.2    Modlich, U.3    Li, Z.4    Fehse, B.5
  • 26
    • 0142089747 scopus 로고    scopus 로고
    • Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer
    • Raper SE, Chirmule N, Lee FS, Wivel NA, Bagg A, et al. (2003) Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer. Mol Genet Metab 80: 148-158.
    • (2003) Mol Genet Metab , vol.80 , pp. 148-158
    • Raper, S.E.1    Chirmule, N.2    Lee, F.S.3    Wivel, N.A.4    Bagg, A.5
  • 27
  • 28
    • 0347917175 scopus 로고    scopus 로고
    • Minimal toxicity of stabilized compacted DNA nanoparticles in the murine lung
    • Ziady AG, Gedeon CR, Muhammad O, Stillwell V, Oette SM, et al. (2003) Minimal toxicity of stabilized compacted DNA nanoparticles in the murine lung. Mol Ther 8: 948-956.
    • (2003) Mol Ther , vol.8 , pp. 948-956
    • Ziady, A.G.1    Gedeon, C.R.2    Muhammad, O.3    Stillwell, V.4    Oette, S.M.5
  • 29
    • 0347354994 scopus 로고    scopus 로고
    • Transfection of airway epithelium by stable PEGylated poly-L-lysine DNA nanoparticles in vivo
    • Ziady AG, Gedeon CR, Miller T, Quan W, Payne JM, et al. (2003) Transfection of airway epithelium by stable PEGylated poly-L-lysine DNA nanoparticles in vivo. Mol Ther 8: 936-947.
    • (2003) Mol Ther , vol.8 , pp. 936-947
    • Ziady, A.G.1    Gedeon, C.R.2    Miller, T.3    Quan, W.4    Payne, J.M.5
  • 32
    • 19944398726 scopus 로고    scopus 로고
    • Compacted DNA nanoparticles administered to the nasal mucosa of cystic fibrosis subjects are safe and demonstrate partial to complete cystic fibrosis transmembrane regulator reconstitution
    • Konstan MW, Davis PB, Wagener JS, Hilliard KA, Stern RC, et al. (2004) Compacted DNA nanoparticles administered to the nasal mucosa of cystic fibrosis subjects are safe and demonstrate partial to complete cystic fibrosis transmembrane regulator reconstitution. Hum Gene Ther 15: 1255-1269.
    • (2004) Hum Gene Ther , vol.15 , pp. 1255-1269
    • Konstan, M.W.1    Davis, P.B.2    Wagener, J.S.3    Hilliard, K.A.4    Stern, R.C.5
  • 33
    • 0035860723 scopus 로고    scopus 로고
    • Biological properties of poly-L-lysine-DNA complexes generated by cooperative binding of the polycation
    • Liu G, Molas M, Grossmann GA, Pasumarthy M, Perales JC, et al. (2001) Biological properties of poly-L-lysine-DNA complexes generated by cooperative binding of the polycation. J Biol Chem 276: 34379-34387.
    • (2001) J Biol Chem , vol.276 , pp. 34379-34387
    • Liu, G.1    Molas, M.2    Grossmann, G.A.3    Pasumarthy, M.4    Perales, J.C.5
  • 34
    • 33645748724 scopus 로고    scopus 로고
    • Retention of function without normal disc morphogenesis occurs in cone but not rod photoreceptors
    • Farjo R, Skaggs JS, Nagel BA, Quiambao AB, Nash ZA, et al. (2006) Retention of function without normal disc morphogenesis occurs in cone but not rod photoreceptors. J Cell Biol 173: 59-68.
    • (2006) J Cell Biol , vol.173 , pp. 59-68
    • Farjo, R.1    Skaggs, J.S.2    Nagel, B.A.3    Quiambao, A.B.4    Nash, Z.A.5
  • 35
    • 0347358078 scopus 로고    scopus 로고
    • Absence of functional and structural abnormalities associated with expression of EGFP in the retina
    • Nour M, Quiambao AB, Al-Ubaidi MR, Naash MI (2004) Absence of functional and structural abnormalities associated with expression of EGFP in the retina. Invest Ophthalmol Vis Sci 45: 15-22.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 15-22
    • Nour, M.1    Quiambao, A.B.2    Al-Ubaidi, M.R.3    Naash, M.I.4
  • 36
    • 4644344753 scopus 로고    scopus 로고
    • Pathogenesis of persistent hyperplastic primary vitreous in mice lacking the arf tumor suppressor gene
    • Martin AC, Thornton JD, Liu J, Wang X, Zuo J, et al. (2004) Pathogenesis of persistent hyperplastic primary vitreous in mice lacking the arf tumor suppressor gene. Invest Ophthalmol Vis Sci 45: 3387-3396.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 3387-3396
    • Martin, A.C.1    Thornton, J.D.2    Liu, J.3    Wang, X.4    Zuo, J.5
  • 37
  • 38
    • 13044256410 scopus 로고    scopus 로고
    • Stable transgene expression in rod photoreceptors after recombinant adeno-associated virus-mediated gene transfer to monkey retina
    • Bennett J, Maguire AM, Cideciyan AV, Schnell M, Glover E, et al. (1999) Stable transgene expression in rod photoreceptors after recombinant adeno-associated virus-mediated gene transfer to monkey retina. Proc Natl Acad Sci U S A 96: 9920-9925.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 9920-9925
    • Bennett, J.1    Maguire, A.M.2    Cideciyan, A.V.3    Schnell, M.4    Glover, E.5
  • 39
    • 0141430039 scopus 로고    scopus 로고
    • P2Y(2) receptor agonist INS37217 enhances functional recovery after detachment caused by subretinal injection in normal and rds mice
    • Nour M, Quiambao AB, Peterson WM, Al-Ubaidi MR, Naash MI (2003) P2Y(2) receptor agonist INS37217 enhances functional recovery after detachment caused by subretinal injection in normal and rds mice. Invest Ophthalmol Vis Sci 44: 4505-4514.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 4505-4514
    • Nour, M.1    Quiambao, A.B.2    Peterson, W.M.3    Al-Ubaidi, M.R.4    Naash, M.I.5
  • 40
    • 20544452086 scopus 로고    scopus 로고
    • Optimization of gene transfer into neonatal rat cardiomyocytes and unmasking of cytomegalovirus promoter silencing
    • Bauer S, Maier SK, Neyses L, Maass AH (2005) Optimization of gene transfer into neonatal rat cardiomyocytes and unmasking of cytomegalovirus promoter silencing. DNA Cell Biol 24: 381-387.
    • (2005) DNA Cell Biol , vol.24 , pp. 381-387
    • Bauer, S.1    Maier, S.K.2    Neyses, L.3    Maass, A.H.4
  • 41
    • 13644267108 scopus 로고    scopus 로고
    • Transcriptional silencing is associated with extensive methylation of the CMV promoter following adenoviral gene delivery to muscle
    • Brooks AR, Harkins RN, Wang P, Qian HS, Liu P, et al. (2004) Transcriptional silencing is associated with extensive methylation of the CMV promoter following adenoviral gene delivery to muscle. J Gene Med 6: 395-404.
    • (2004) J Gene Med , vol.6 , pp. 395-404
    • Brooks, A.R.1    Harkins, R.N.2    Wang, P.3    Qian, H.S.4    Liu, P.5
  • 42
    • 2642519089 scopus 로고    scopus 로고
    • Silencing of episomal transgene expression by plasmid bacterial DNA elements in vivo
    • Chen ZY, He CY, Meuse L, Kay MA (2004) Silencing of episomal transgene expression by plasmid bacterial DNA elements in vivo. Gene Ther 11: 856-864.
    • (2004) Gene Ther , vol.11 , pp. 856-864
    • Chen, Z.Y.1    He, C.Y.2    Meuse, L.3    Kay, M.A.4
  • 44
    • 0347388017 scopus 로고    scopus 로고
    • Intracellular trafficking of non-targeted stabilized molecular conjugates in human airway epithelia cells
    • Kube D, Davis PB (2003) Intracellular trafficking of non-targeted stabilized molecular conjugates in human airway epithelia cells. Mol Ther 7: S371.
    • (2003) Mol Ther , vol.7
    • Kube, D.1    Davis, P.B.2
  • 45
    • 33846830274 scopus 로고    scopus 로고
    • Compacted DNA nanoparticles transfect cells by binding to cell surface nucleolin
    • Chen X, Davis, B P (2006) Compacted DNA nanoparticles transfect cells by binding to cell surface nucleolin. Mol Ther 13: S397.
    • (2006) Mol Ther , vol.13
    • Chen, X.1    Davis, B.P.2
  • 47
    • 0346957021 scopus 로고    scopus 로고
    • Prospects for gene therapy in corneal disease
    • Jun AS, Larkin DF (2003) Prospects for gene therapy in corneal disease. Eye 17: 906-911.
    • (2003) Eye , vol.17 , pp. 906-911
    • Jun, A.S.1    Larkin, D.F.2
  • 48
    • 9944226710 scopus 로고    scopus 로고
    • Gene therapy for optic nerve disease
    • Martin KR, Quigley HA (2004) Gene therapy for optic nerve disease. Eye 18: 1049-1055.
    • (2004) Eye , vol.18 , pp. 1049-1055
    • Martin, K.R.1    Quigley, H.A.2
  • 50
    • 0141430092 scopus 로고    scopus 로고
    • Gene therapy with brain-derived neurotrophic factor as a protection: Retinal ganglion cells in a rat glaucoma model
    • Martin KR, Quigley HA, Zack DJ, Levkovitch-Verbin H, Kielczewski J, et al. (2003) Gene therapy with brain-derived neurotrophic factor as a protection: retinal ganglion cells in a rat glaucoma model. Invest Ophthalmol Vis Sci 44: 4357-4365.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 4357-4365
    • Martin, K.R.1    Quigley, H.A.2    Zack, D.J.3    Levkovitch-Verbin, H.4    Kielczewski, J.5
  • 51
    • 33745712928 scopus 로고    scopus 로고
    • Oncomodulin is a macrophage-derived signal for axon regeneration in retinal ganglion cells
    • Yin Y, Henzl MT, Lorber B, Nakazawa T, Thomas TT, et al. (2006) Oncomodulin is a macrophage-derived signal for axon regeneration in retinal ganglion cells. Nat Neurosci 9: 843-852.
    • (2006) Nat Neurosci , vol.9 , pp. 843-852
    • Yin, Y.1    Henzl, M.T.2    Lorber, B.3    Nakazawa, T.4    Thomas, T.T.5
  • 52
    • 33645974269 scopus 로고    scopus 로고
    • Ectopic expression of a microbial-type rhodopsin restores visual responses in mice with photoreceptor degeneration
    • Bi A, Cui J, Ma YP, Olshevskaya E, Pu M, et al. (2006) Ectopic expression of a microbial-type rhodopsin restores visual responses in mice with photoreceptor degeneration. Neuron 50: 23-33.
    • (2006) Neuron , vol.50 , pp. 23-33
    • Bi, A.1    Cui, J.2    Ma, Y.P.3    Olshevskaya, E.4    Pu, M.5
  • 54
    • 23744485151 scopus 로고    scopus 로고
    • Towards mutation-independent silencing of genes involved in retinal degeneration by RNA interference
    • Cashman SM, Binkley EA, Kumar-Singh R (2005) Towards mutation-independent silencing of genes involved in retinal degeneration by RNA interference. Gene Ther 12: 1223-1228.
    • (2005) Gene Ther , vol.12 , pp. 1223-1228
    • Cashman, S.M.1    Binkley, E.A.2    Kumar-Singh, R.3
  • 55
    • 20244380171 scopus 로고    scopus 로고
    • Complement factor H polymorphism in age-related macular degeneration
    • Klein RJ, Zeiss C, Chew EY, Tsai JY, Sackler RS, et al. (2005) Complement factor H polymorphism in age-related macular degeneration. Science 308: 385-389.
    • (2005) Science , vol.308 , pp. 385-389
    • Klein, R.J.1    Zeiss, C.2    Chew, E.Y.3    Tsai, J.Y.4    Sackler, R.S.5
  • 56
    • 17244379811 scopus 로고    scopus 로고
    • Complement factor H polymorphism and age-related macular degeneration
    • Edwards AO, Ritter R 3rd, Abel KJ, Manning A, Panhuysen C, et al. (2005) Complement factor H polymorphism and age-related macular degeneration. Science 308: 421-424.
    • (2005) Science , vol.308 , pp. 421-424
    • Edwards, A.O.1    Ritter 3rd, R.2    Abel, K.J.3    Manning, A.4    Panhuysen, C.5
  • 57
    • 20244388812 scopus 로고    scopus 로고
    • Complement factor H variant increases the risk of age-related macular degeneration
    • Haines JL, Hauser MA, Schmidt S, Scott WK, Olson LM, et al. (2005) Complement factor H variant increases the risk of age-related macular degeneration. Science 308: 419-421.
    • (2005) Science , vol.308 , pp. 419-421
    • Haines, J.L.1    Hauser, M.A.2    Schmidt, S.3    Scott, W.K.4    Olson, L.M.5
  • 58
    • 20544433415 scopus 로고    scopus 로고
    • Toll-like receptor 4 variant D299G is associated with susceptibility to age-related macular degeneration
    • Zareparsi S, Buraczynska M, Branham KE, Shah S, Eng D, et al. (2005) Toll-like receptor 4 variant D299G is associated with susceptibility to age-related macular degeneration. Hum Mol Genet 14: 1449-1455.
    • (2005) Hum Mol Genet , vol.14 , pp. 1449-1455
    • Zareparsi, S.1    Buraczynska, M.2    Branham, K.E.3    Shah, S.4    Eng, D.5
  • 59
    • 30744476478 scopus 로고    scopus 로고
    • Retinal angiogenesis in development and disease
    • Gariano RF, Gardner TW (2005) Retinal angiogenesis in development and disease. Nature 438: 960-966.
    • (2005) Nature , vol.438 , pp. 960-966
    • Gariano, R.F.1    Gardner, T.W.2
  • 60
    • 33645331188 scopus 로고    scopus 로고
    • Tolerability and efficacy of multiple escalating doses of ranibizumab (Lucentis) for neovascular age-related macular degeneration
    • Rosenfeld PJ, Heier JS, Hantsbarger G, Shams N (2006) Tolerability and efficacy of multiple escalating doses of ranibizumab (Lucentis) for neovascular age-related macular degeneration. Ophthalmology 113: 632.
    • (2006) Ophthalmology , vol.113 , pp. 632
    • Rosenfeld, P.J.1    Heier, J.S.2    Hantsbarger, G.3    Shams, N.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.