Long-term rescue of retinal structure and function by rhodopsin RNA replacement with a single adeno-associated viral vector in P23H RHO transgenic mice

Human Gene Therapy

Volumn 23, Issue 4, 2011, Pages 356-366

  Mao, Haoyu ^a   Gorbatyuk, Marina S ^b   Rossmiller, Brian ^a   Hauswirth, William W ^a,c   Lewin, Alfred S ^a  

^a UNIVERSITY OF FLORIDA   (United States)

^b UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA; PARVOVIRUS VECTOR; RHODOPSIN; SMALL INTERFERING RNA;

ADENO ASSOCIATED VIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOSOMAL DOMINANT DISORDER; CONTROLLED STUDY; ELECTRORETINOGRAPHY; GENE; GENE MUTATION; GENE OVEREXPRESSION; GENE REPLACEMENT THERAPY; HUMAN; MOUSE; NONHUMAN; PHOTORECEPTOR; PHOTORECEPTOR OUTER SEGMENT; RETINA; RETINITIS PIGMENTOSA; RHO GENE; TRANSGENIC MOUSE; WILD TYPE;

ANIMALS; DEPENDOVIRUS; GENETIC THERAPY; GENETIC VECTORS; MICE; MICE, TRANSGENIC; RETINA; RETINITIS PIGMENTOSA; RHODOPSIN; RNA;

EID: 84860175219     PISSN: 10430342     EISSN: 15577422     Source Type: Journal    
DOI: 10.1089/hum.2011.213     Document Type: Article

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