Functional expression of Rab escort protein 1 following AAV2-mediated gene delivery in the retina of choroideremia mice and human cells ex vivo

Journal of Molecular Medicine

Volumn 91, Issue 7, 2013, Pages 825-837

  Tolmachova, Tanya ^a   Tolmachov, Oleg E ^a   Barnard, Alun R ^b   De Silva, Samantha R ^b   Lipinski, Daniel M ^b   Walker, Nathan J ^b,c   MacLaren, Robert E ^b,c   Seabra, Miguel C ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c MOORFIELDS EYE HOSPITAL   (United Kingdom)

Author keywords

AAV; Choroideremia; Gene therapy; Rab escort protein 1; Rab GTPase; Retinitis pigmentosa

Indexed keywords

BETA ACTIN; COMPLEMENTARY DNA; GREEN FLUORESCENT PROTEIN; RAB ESCORT PROTEIN 1; RAB PROTEIN; UNCLASSIFIED DRUG;

ADENO ASSOCIATED VIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL CULTURE; CHOROIDEREMIA; CONTROLLED STUDY; EX VIVO STUDY; FIBROBLAST; GENE TARGETING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; OSTEOSARCOMA; PIGMENT EPITHELIUM; PROTEIN EXPRESSION; REGULATORY SEQUENCE; TRANSGENE; WILD TYPE; WOODCHUCK HEPATITIS VIRUS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL LINE, TUMOR; CELLS, CULTURED; CHOROIDEREMIA; DEPENDOVIRUS; DNA, COMPLEMENTARY; DOGS; FEMALE; FIBROBLASTS; GENE TRANSFER TECHNIQUES; HUMANS; MICE; MICE, TRANSGENIC; RETINA;

EID: 84879842921     PISSN: 09462716     EISSN: 14321440     Source Type: Journal    
DOI: 10.1007/s00109-013-1006-4     Document Type: Article

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