A powerful nonviral vector for in vivo gene transfer into the adult mammalian brain: Polyethylenimine

Human Gene Therapy

Volumn 7, Issue 16, 1996, Pages 1947-1954

  Abdallah, Bassima ^a   Hassan, Ahmed ^a   Benoist, Corinne ^a   Goula, Daniel ^a   Behr, Jean Paul ^b   Demeneix, Barbara A ^a  

^a MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

^b CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; LUCIFERASE; POLYETHYLENEIMINE; PROTEIN BCL 2;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN CORTEX; CONTROLLED STUDY; CYTOMEGALOVIRUS; DNA TRANSFECTION; FEMALE; GENE EXPRESSION; GENE TARGETING; GENE TRANSFER; GLIA; HIPPOCAMPUS; HYPOTHALAMUS; MALE; MOUSE; NERVE CELL; NONHUMAN; REPORTER GENE; TRANSGENE;

ANIMALIA; CYTOMEGALOVIRUS; MAMMALIA;

EID: 0029799791     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.1996.7.16-1947     Document Type: Article

References (30)

1. AKLI, S., CAILLAUD, C., VIGNE, E., STRATFORD-PERRICAUDET, L.D., POENARU, L., PERRICAUDET, M., KAHN, A., and PESCHANSKI, M.R. (1993). Transfer of a foreign gene into the brain using adenovirus vectors. Nature Genet. 3, 224-228.
2. AUSUBEL, F.M., BRENT, R., KINGSTON, R.E., MOORE, D.D., SEIDMAN, J.G., SMITH, J.A., and STRUHL, K. (1994). Plasmid DNA purification by PEG precipitation. In Current Protocols in Molecular Biology, vol. 1. (John Wiley & Sons, Inc.) pp. 1.7.9-1.8.
3. BAJOCCHI, G., FELDMAN, S.H., CRYSTAL, R.G., and MASTRANGELI, A. (1993). Direct in vivo gene transfer to ependymal cells in the central nervous system using recombinant adenovirus vectors. Nature Genet 3, 229-234.
4. BARBA, D., HARDIN, J., SADELAIN, M., and GAGE, F.H. (1994). Development of anti-tumor immunity following thymidine kinase-mediated killing of experimental brains tumors. Proc. Natl. Acad. Sci. USA 91, 4348-1352.
5. BEHR, J., DEMENEIX, B., LOEFFLER, J., and PEREZ-MUTUL, J. (1989). Efficient gene transfer into mammalian primary endocrine cells with lipopolyamine-coated DNA. Proc. Natl. Acad. Sci. USA 86, 6982-6986.
6. BOUSSIF, O., LEZOUALC'H, F., ZANTA, M.A., MERGNY, M., SCHERMAN, D., DEMENEIX, B., and BEHR, J.-P. (1995). A novel, versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: Polyethylenimine. Proc. Natl. Acad. Sci. USA 92, 7297-7303.
7. BOVIATSIS, E.J., CHASE, M., WEI, M.X., TAMIYA, T., HURFORD, R.K., KOWALL, N.W., TEPPER, R.I., BREAKEFIELD, X.O., and CHIOCCA, E.A. (1994). Gene transfer into experimental brain tumors mediated by adenovirus, herpes simplex virus and retrovirus vectors. Hum. Gene Ther. 5, 183-191.
8. CHAMBERS, R., GILLESPIE, G.Y., SOROCEANU, L., ANDREANSKY, S., CHATTERJEE, S., CHOU, J., ROIZMAN, B., and WHITLEY, R.J. (1995). Comparison of genetically engineered herpes simplex viruses for the treatment of brain tumors in a scid mouse model of human malignant glioma. Proc. Natl. Acad. Sci. USA 92, 1411-1415.
9. COTTEN, M., BAKER, A., SALTIK, M., WAGNER, E., and BUSCHLE, M. (1994). Lipopolysaccharide is a frequent contaminant of plasmid DNA preparations and can be toxic to primary human cells in the presence of adenovirus. Gene Ther. 1, 239.
10. CULVER, K.W., RAM, Z., WALLBRIDGE, S., ISHII, H., OLDFIELD, E.H., and BLAESE, R.M. (1992). In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors. Science 256, 1550-1552.
11. DAVIDSON, B.L., ALLEN, E.D., KOZARSKY, K.F., WILSON, J.M., and ROESSLER, B.J. (1993). A model system for in vivo gene transfer into the central nervous system using an adenoviral vector. Nature Genet. 3, 219-223.
12. DAVIS, H.L., WHALEN, R.G., and DEMENEIX, B.A. (1993). Direct gene transfer into skeletal muscle in vivo: Factors affecting efficiency of transer and stability of expression. Hum. Gene Ther. 4, 151-159.
13. FELGNER, P.L., GADEK, T.R., HOLM, M., ROMAN, R., CHAN, H.W., WENZ, M., NORTHROP, J.P., RINGOLD, G.M., and DANIELSEN, M. (1987). Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure. Proc. Natl. Acad. Sci. USA 84, 7413-7417.
14. GARCIA, I., MARTINOU, I., YOSHIHIDE, T., and MARTINOU, J.C. (1992). Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene. Science 258, 302-304.
15. KAPLITT, M.G., LEONE, P., SALMUSKI, R., XIAO, X., PFAFF, D.W., O'MALLEY, K.L., and DURING, M.J. (1994). Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain. Nature Genet. 8, 148-153.
16. KESARI, S., RANDAZZO, B.P., VALYI-NAGY, T., HUANG, Q.S., BROWN, S.M., MACLEAN, A.R., LEE, V.M., TROJANOWSKI, J.Q., and FRASER, N.W. (1995). Therapy of experimental human brain tumors using a neuroattenuated herpes simplex virus mutant. Lab. Invest. 73, 636-648.
17. LE GAL LA SALLE, G., ROBERT, J.J., BERRARD, S., RIDOUX, V., STRADFORD-PERRICAUDET, L.D., PERRICAUDET, M., and MALLET, J. (1993). An adenovirus vector for gene transfer into neurons and glia in the brain. Science 259, 988-990.
18. LEUMANN, A. (1974). Atlas stéréotaxique du cerveau de la souris. (Editones du CNRS, Paris).
19. MANTHORPE, M., CORNEFERT-JENSEN, F., HARTIKKA, J., FELGNER, P.L., RUNDELL, A., MARGALITH, M., and DWARKI, V. (1993). Gene therapy by intramuscular injection of plasmid DNA: studies on firefly luciferase gene expression in mice. Hum. Gene Ther. 4, 419-431.
20. MCKAY, R.D.G. (1989). The origins of cellular diversity in the mammalian central nervous system. Cell 58, 815-851.
21. NALDINI, L., BLOMER, U., GALLAY, P., ORY, D., MULLIGAN, R., GAGE, F.H., VERMA, I.M., and TRONO, D., (1996). In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 272, 263-267.
22. ONO, T., FUJINO, Y., TSUCHIUA, T., and TSUDA, M. (1990). Plasmid DNAs directly injected into mouse brain with lipofectin can be incorporated and expressed by brain cells. Neurosci. Lett. 117, 259-263.
23. PAKZABAN, P., GELLER, A.I., and ISACSON, O. (1994). Effect of exogenous nerve growth factor on neurotoxicity of and neuronal gene delivery by a Herpes simplex amplicon vector in the rat brain. Hum. Gene Ther. 5, 987-995.
24. ROESSLER, B.J., and DAVIDSON, B.L. (1994). Direct plasmid mediated transfection of adult murine brain cells in vivo using cationic liposomes. Neurosci. Lett 167, 5-10.
25. SAMBROOK, J., FRITSCH, E.F., and MANIATIS, T. (1989). Molecular Cloning: A Laboratory Manual. (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY).
26. SCHWARTZ, B., BENOIST, C., ABDALLAH, B., SCHERMAN, D., BEHR, J.P., and DEMEINEX, B.A. (1995). Lipospermine-based gene transfer into the newborn mouse brain is optimized by a low lipospermine/DNA charge ratio. Hum. Gene Ther. 6, 1515-1524.
27. SCHWARTZ, B., ABDALLAH, B., BENOIST, C., RANGARA, R., HASSAN, A., SCHERMAN, D., and DEMENEIX, B. (1996). Gene transfer by naked DNA into adult mouse brain. Gene Ther. 3, 405-411.
28. SNYDER, E.Y., TAYLOR, R.M., and WOLFE, J.H. (1995). Neural progenitor cell engraftment corrects lysosomal storage throughout the MPS VII mouse brain. Nature 374, 367-370.
29. WOOD, M.J., BYRNES, A.P., PFAFF, D.W., RABKIN, S.D., and CHARLTON, H.M. (1994). Inflammatory effects of gene transfer into the CNS with defective HSV-1 vectors. Gene Ther. 1, 283-291.
30. ZHANG, L.X., WU, M., and HAN, J.S. (1992). Suppression of audiogenic epileptic seizures by intracerebral injection of a CCK gene vector. NeuroReport 3, 700-702.