Design of imidazole-containing endosomolytic biopolymers for gene delivery

Biotechnology and Bioengineering

Volumn 67, Issue 2, 2000, Pages 217-223

  Pack, Daniel W ^a,b   Putnam, David ^a   Langer, Robert ^a  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Chloroquine; Endosomolytic polymer; Gene delivery; Polycations; Polyhistidine; Polyplexes

Indexed keywords

AMINO ACIDS; ANIMAL CELL CULTURE; BIOCOMPATIBILITY; BIOPOLYMERS; BIOSYNTHESIS; PHYSIOLOGICAL MODELS;

ENDOSOMOLYTIC BIOPOLYMERS; GENE DELIVERY; IMIDAZOLE;

GENETIC ENGINEERING;

BIOPOLYMER; IMIDAZOLE DERIVATIVE;

ANIMAL CELL; ARTICLE; BIOCOMPATIBILITY; BIOTECHNOLOGY; GENE TARGETING; GENE TECHNOLOGY; GENE THERAPY; GENETIC TRANSFECTION; NONHUMAN;

ANIMALS; BIOCOMPATIBLE MATERIALS; BIOPOLYMERS; CHLOROQUINE; COS CELLS; DNA; DRUG CARRIERS; DRUG DESIGN; ELECTROPHORESIS; ENDOSOMES; GENE THERAPY; GLUCONATES; HISTIDINE; IMIDAZOLES; PEPTIDES; TRANSFERRIN;

EID: 0034688198     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0290(20000120)67:2<217::AID-BIT11>3.0.CO;2-Q     Document Type: Article

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