Low generation PAMAM dendrimer and CpG free plasmids allow targeted and extended transgene expression in tumors after systemic delivery

Journal of Controlled Release

Volumn 146, Issue 1, 2010, Pages 99-105

  Navarro, Gemma ^a   Maiwald, Gelja ^b   Haase, Rudolf ^b   Rogach, Andrey L ^b,c   Wagner, Ernst ^b   de Ilarduya, Conchita Tros ^a   Ogris, Manfred ^b  

^a UNIVERSITY OF NAVARRA   (Spain)

^b UNIVERSITY OF MUNICH   (Germany)

^c CITY UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

CpG free plasmid; PAMAM dendrimer; Tumor targeting

Indexed keywords

BIOLOGICAL ORGANS; DENDRIMERS; DNA; INFRARED DEVICES; MAMMALS; SEMICONDUCTOR QUANTUM DOTS; TUMORS;

BIOLUMINESCENCE IMAGING; CPG FREE PLASMID; INTRAVENOUS INJECTIONS; LUCIFERASE ACTIVITIES; LUCIFERASE EXPRESSION; PAMAM DENDRIMER; REPORTER-GENE EXPRESSION; TUMOR TARGETING;

GENE EXPRESSION;

CPG OLIGODEOXYNUCLEOTIDE; DENDRIMER; ELONGATION FACTOR 1; LUCIFERASE; PLASMID DNA; POLYAMIDOAMINE; QUANTUM DOT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOACCUMULATION; BIOLUMINESCENCE; CONTROLLED STUDY; CYTOMEGALOVIRUS; DRUG DELIVERY SYSTEM; DRUG TARGETING; ENHANCER REGION; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; GENETIC TRANSFECTION; IMMUNOCOMPETENCE; IMMUNOMODULATION; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NEUROBLASTOMA; NONHUMAN; NUDE MOUSE; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; SEMICONDUCTOR; TRANSGENE; TUMOR CELL; TUMOR XENOGRAFT;

EID: 77955272031     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2010.04.030     Document Type: Article

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