Optimizing viral and non-viral gene transfer methods for genetic modification of porcine mesenchymal stem cells

Advances in Experimental Medicine and Biology

Volumn 585, Issue , 2006, Pages 31-48

  Stiehler, Maik ^a,b   Duch, Mogens ^b   Mygind, Tina ^a   Li, Haisheng ^a   Ulrich Vinther, Michael ^a   Modin, Charlotte ^b   Baatrup, Anette ^a   Lind, Martin ^a   Pedersen, Finn S ^b   Bünger, Cody E ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84934436442     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-0-387-34133-0_3     Document Type: Conference Paper

References (30)

1. S.E. Haynesworth, J. Goshima, V.M. Goldberg, and A.I. Caplan, Characterization of cells with osteogenic potential from human marrow, Bone 13(1), 81-88 (1992).
2. M.F. Pittenger, A.M. Mackay, S.C. Beck, R.K. Jaiswal, R. Douglas, J.D. Mosca, M.A. Moorman, D.W. Simonetti, S. Craig, and D.R. Marshak, Multilineage potential of adult human mesenchymal stem cells, Science 284(5411), 143-147 (1999).
3. H.A. Awad, D.L. Butler, G.P. Boivin, F.N. Smith, P. Malaviya, B. Huibregtse, and A.I. Caplan, Autologous mesenchymal stem cell-mediated repair of tendon, Tissue Eng. 5(3), 267-277 (1999).
4. G. Ferrari, G. Cusella-De Angelis, M. Coletta, E. Paolucci, A. Stornaiuolo, G. Cossu, and F. Mavilio, Muscle regeneration by bone marrow-derived myogenic progenitors, Science 279(5356), 1528-1530 (1998).
5. P. Bianco and P.G. Robey, Stem cells in tissue engineering, Nature 414(6859), 118-121 (2001).
6. F. Gori, T. Thomas, K.C. Hicok, T.C. Spelsberg, and B.L. Riggs, Differentiation of human marrow stromal precursor cells: bone morphogenetic protein-2 increases OSF2/CBFA1, enhances osteoblast commitment, and inhibits late adipocyte maturation, J. Bone Miner. Res. 14(9), 1522-1535 (1999).
7. A.I. Caplan, Mesenchymal stem cells and gene therapy, Clin. Orthop. 379, S67-S70 (2000).
8. K.W. Culver and R.M. Blaese, Gene therapy for cancer, Trends Genet. 10(5), 174-178 (1994).
9. V. Cottard, D. Mulleman, P. Bouille, M. Mezzina, M.C. Boissier, and N. Bessis, Adeno-associated virus-mediated delivery of IL-4 prevents collagen-induced arthritis, Gene Ther. 7(22), 1930-1939 (2000).
10. K.R. Clark, T.J. Sferra, and P.R. Johnson, Recombinant adeno-associated viral vectors mediate long-term transgene expression in muscle, Hum. Gene Ther. 8(6), 659-669 (1997).
11. D. Duan, P. Sharma, J. Yang, Y. Yue, L. Dudus, Y. Zhang, K.J. Fisher, and J.F. Engelhardt, Circular intermediates of recombinant adeno-associated virus have defined structural characteristics responsible for long-term episomal persistence in muscle tissue, J. Virol. 72(11), 8568-8577 (1998).
12. M.G. Kaplitt, P. Leone, R.J. Samulski, X. Xiao, D.W. Pfaff, K.L. O'Malley, and M.J. During, Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain, Nat. Genet. 8(2), 148-154 (1994).
13. T. Ikeda, T. Kubo, Y. Arai, T. Nakanishi, K. Kobayashi, K. Takahashi, J. Imanishi, M. Takigawa, and Y.Hirasawa, Adenovirus mediated gene delivery to the joints of guinea pigs, J. Rheumatol. 25(9), 1666-1673 (1998).
14. A.M. Douar, K. Poulard, D. Stockholm, and O. Danos, Intracellular trafficking of adeno-associated virus vectors: routing to the late endosomal compartment and proteasome degradation, J. Virol. 75(4), 1824-1833 (2001).
15. J. Goater, R. Muller, G. Kollias, G.S. Firestein, I. Sanz, R.J. O'Keefe, and E.M. Schwarz, Empirical advantages of adeno associated viral vectors in vivo gene therapy for arthritis, J. Rheumatol. 27(4): 983-989 (2000).
16. X. Xiao, J. Li, and R.J. Samulski, Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus, J. Virol. 72(3), 2224-2232 (1998).
17. F. S. Pedersen and M. Duch, Retroviruses in human gene therapy, Encyclopedia of Life Sciences (2003); http://els.wiley.com.
18. M. Ulrich-Vinther, M.D. Maloney, J.J. Goater, K. Soballe, M.B. Goldring, R.J. O'Keefe, and E.M. Schwarz, Light-activated gene transduction enhances adeno-associated virus vector-mediated gene expression in human articular chondrocytes, Arthritis Rheum. 46(8), 2095-2104 (2002).
19. D. Klein, S. Indraccolo, K. von Rombs, A. Amadori, B. Salmons, and W.H. Gunzburg, Rapid identification of viable retrovirus-transduced cells using the green fluorescent protein as a marker, Gene Ther. 4(11), 1256-1260 (1997).
20. rd, S. Zhang, Y.L. Chiang, E. Otto, L. Weaver, R.M. Blaese, W.F.Anderson, and G.J.McGarrity, Improved methods of retroviral vector transduction and production for gene therapy, Hum. Gene Ther. 5(1), 19-28 (1994).
21. K.A. Partridge and R.O. Oreffo, Gene delivery in bone tissue engineering: progress and prospects using viral and nonviral strategies, Tissue Eng. 10(1-2), 295-307 (2004).
22. A.M. Douar, K. Poulard, D. Stockholm, and O. Danos, Intracellular trafficking of adeno-associated virus vectors: routing to the late endosomal compartment and proteasome degradation, J Virol 75(4):1824-1833 (2001).
23. G. Seisenberger, M.U. Ried, T. Endress, H. Buning, M. Hallek, and C. Brauchle, Real-time single-molecule imaging of the infection pathway of an adeno-associated virus." Science 2001.Nov.30.;294.(5548.):1929.-32. 294,(November 2001):1929-32.
24. T.R. Flotte, S.A. Afione, and P.L. Zeitlin, Adeno-associated virus vector gene expression occurs in nondividing cells in the absence of vector DNA integration, Am. J. Respir. Cell Mol. Biol. 11(5), 517-521 (1994).
25. G. Seisenberger, M.U. Ried, T. Endress, H. Buning, M. Hallek, and C. Brauchle, Real-time single-molecule imaging of the infection pathway of an adeno-associated virus, Science 294(5548), 1929-1932 (2001).
26. K.J. Fisher, G.P. Gao, M.D. Weitzman, R. DeMatteo, J.F. Burda, and J.M. Wilson, Transduction with recombinant adeno-associated virus for gene therapy is limited by leading-strand synthesis, J. Virol. 70(1), 520-532 (1996).
27. J.D. Mosca, J.K. Hendricks, D. Buyaner, J. Davis-Sproul, L.C. Chuang, M.K. Majumdar, R. Chopra, F. Barry, M. Murphy, M.A. Thiede, U. Junker, R.J. Rigg, S.P. Forestell, E. Bohnlein, R. Storb, and B.M. Sandmaier, Mesenchymal stem cells as vehicles for gene delivery, Clin. Orthop. 379, S71-S90 (2000).
28. S. Hacein-Bey-Abina, C. von Kalle, M. Schmidt, M.P. McCormack, N. Wulffraat, P. Leboulch, A. Lim, C.S.Osborne, R.Pawliuk, E.Morillon, R.Sorensen, A.Forster, P.Fraser, J.I.Cohen, B.G.de Saint, I. Alexander, U. Wintergerst, T. Frebourg, A. Aurias, D. Stoppa-Lyonnet, S. Romana, I. Radford-Weiss, F. Gross, F. Valensi, E. Delabesse, E. Macintyre, F. Sigaux, J. Soulier, L.E. Leiva, M. issler, C. Prinz, T.H. Rabbitts, F. Le Deist, A. Fischer, and M. Cavazzana-Calvo, LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1, Science 302(5644), 415-419 (2003).
29. H.P. Kiem, S. Sellers, B. Thomasson, J.C. Morris, J.F. Tisdale, P.A. Horn, P. Hematti, R. Adler, K. Kuramoto, B. Calmels, A. Bonifacino, J. Hu, C. von Kalle, M. Schmidt, B. Sorrentino, A. Nienhuis, C.A. Blau, R.G. Andrews, R.E. Donahue, and C.E. Dunbar, Long-term clinical and molecular follow-up of large animals receiving retrovirally transduced stem and progenitor cells: no progression to clonal hematopoiesis or leukemia, Mol. Ther. 9(3), 389-395 (2004).
30. M. Duch, K. Paludan, J. Lovmand, M.S. Sorensen, P. Jorgensen, and F.S. Pedersen, The effect of selection for high-level vector expression on the genetic and functional stability of a single transcript vector derived from a low-leukemogenic murine retrovirus, Hum. Gene Ther. 6(3), 289-296 (1995).