Effect of gene therapy on visual function in Leber's congenital amaurosis

New England Journal of Medicine

Volumn 358, Issue 21, 2008, Pages 2231-2239

  Bainbridge, James W B ^a,b   Smith, Alexander J ^a   Barker, Susie S ^a   Robbie, Scott ^a   Henderson, Robert ^a   Balaggan, Kamaljit ^a   Viswanathan, Ananth ^a,b   Holder, Graham E ^a,b   Stockman, Andrew ^a   Tyler, Nick ^c   Petersen Jones, Simon ^e   Bhattacharya, Shomi S ^a   Thrasher, Adrian J ^d   Fitzke, Fred W ^a   Carter, Barrie J ^f   Rubin, Gary S ^a,b   Moore, Anthony T ^a,b   Ali, Robin R ^a,b,d  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b MOORFIELDS EYE HOSPITAL   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

^e MICHIGAN STATE UNIVERSITY   (United States)

^f Targeted Genetics Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATROPINE; BETAMETHASONE; CEFUROXIME; CHLORAMPHENICOL; COMPLEMENTARY DNA; DEXAMETHASONE; PARVOVIRUS VECTOR; PREDNISOLONE; RECOMBINANT PROTEIN; RETINAL PIGMENT EPITHELIUM SPECIFIC 65;

ADOLESCENT; ADULT; ARTICLE; BLINDNESS; CASE REPORT; CLINICAL TRIAL; DARK ADAPTATION; DRUG EFFICACY; DRUG SAFETY; ELECTRORETINOGRAPHY; EYE INFLAMMATION; GENE REPLACEMENT THERAPY; GOLDMANN PERIMETRY; HUMAN; LEBER CONGENITAL AMAUROSIS; MICROPERIMETRY; MISSENSE MUTATION; PERIMETRY; PRIORITY JOURNAL; PROMOTER REGION; RETINA; RETINA DYSTROPHY; VIRAL GENE DELIVERY SYSTEM; VISUAL ACUITY; VISUAL FIELD; VISUAL IMPAIRMENT; VITRECTOMY;

EID: 44249120315     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMoa0802268     Document Type: Article

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