-
1
-
-
0342817350
-
Types of visble variations induced by X-rays in Drosophila
-
Muller HJ (1930) Types of visble variations induced by X-rays in Drosophila. J Genet 22:299-334
-
(1930)
J Genet
, vol.22
, pp. 299-334
-
-
Muller, H.J.1
-
2
-
-
34249296562
-
Position-effect variegation, heterochromatin formation, and gene silencing in Drosophila
-
C.D. Allis T. Jenuwein D. Reinberg (eds) Cold Spring Harbor Press Cold Spring Harbor
-
Elgin SC, Reuter G (2007) Position-effect variegation, heterochromatin formation, and gene silencing in Drosophila. In: Allis CD, Jenuwein T, Reinberg D (eds) Epigenetics. Cold Spring Harbor Press, Cold Spring Harbor, pp 81-100
-
(2007)
Epigenetics
, pp. 81-100
-
-
Elgin, S.C.1
Reuter, G.2
-
3
-
-
0025201982
-
Position effect at S. Cerevisiae telomeres: Reversible repression of Pol II transcription
-
1:CAS:528:DyaK3MXhvVamtA%3D%3D 2225075
-
Gottschling DE, Aparicio OM, Billington BL, Zakian VA (1990) Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription. Cell 63:751-762
-
(1990)
Cell
, vol.63
, pp. 751-762
-
-
Gottschling, D.E.1
Aparicio, O.M.2
Billington, B.L.3
Zakian, V.A.4
-
4
-
-
84912010919
-
Epigenetics in Saccharomyces cerevisiae
-
C.D. Allis T. Jenuwein D. Reinberg (eds) Cold Spring Harbor Press Cold Spring Harbor
-
Grunstein M, Gasser SM (2007) Epigenetics in Saccharomyces cerevisiae. In: Allis CD, Jenuwein T, Reinberg D (eds) Epigenetics. Cold Spring Harbor Press, Cold Spring Harbor, pp 63-81
-
(2007)
Epigenetics
, pp. 63-81
-
-
Grunstein, M.1
Gasser, S.M.2
-
5
-
-
76949127123
-
Chromosome organization and genic expression
-
1:STN:280:DyaG38%2Fnt1ygtQ%3D%3D 14942727
-
McClintock B (1951) Chromosome organization and genic expression. Cold Spring Harb Symp Quant Biol 16:13-47
-
(1951)
Cold Spring Harb Symp Quant Biol
, vol.16
, pp. 13-47
-
-
McClintock, B.1
-
6
-
-
3342927934
-
Role of transposable elements in heterochromatin and epigenetic control
-
1:CAS:528:DC%2BD2cXlvVaksLk%3D 15269773
-
Lippman Z, Gendrel AV, Black M, Vaughn MW, Dedhia N, McCombie WR, Lavine K, Mittal V, May B, Kasschau KD et al (2004) Role of transposable elements in heterochromatin and epigenetic control. Nature 430:471-476
-
(2004)
Nature
, vol.430
, pp. 471-476
-
-
Lippman, Z.1
Gendrel, A.V.2
Black, M.3
Vaughn, M.W.4
Dedhia, N.5
McCombie, W.R.6
Lavine, K.7
Mittal, V.8
May, B.9
Kasschau, K.D.10
-
7
-
-
77953809032
-
Distinct epigenomic landscapes of pluripotent and lineage-committed human cells
-
1:CAS:528:DC%2BC3cXms1alt7s%3D 2867844 20452322
-
Hawkins RD, Hon GC, Lee LK, Ngo Q, Lister R, Pelizzola M, Edsall LE, Kuan S, Luu Y, Klugman S et al (2010) Distinct epigenomic landscapes of pluripotent and lineage-committed human cells. Cell Stem Cell 6:479-491
-
(2010)
Cell Stem Cell
, vol.6
, pp. 479-491
-
-
Hawkins, R.D.1
Hon, G.C.2
Lee, L.K.3
Ngo, Q.4
Lister, R.5
Pelizzola, M.6
Edsall, L.E.7
Kuan, S.8
Luu, Y.9
Klugman, S.10
-
8
-
-
39049171403
-
Long-range gene control and genetic disease
-
1:CAS:528:DC%2BD1cXmtF2isrg%3D 18282513
-
Kleinjan DA, Lettice LA (2008) Long-range gene control and genetic disease. Adv Genet 61:339-388
-
(2008)
Adv Genet
, vol.61
, pp. 339-388
-
-
Kleinjan, D.A.1
Lettice, L.A.2
-
9
-
-
0037047439
-
Inappropriate gene activation in FSHD: A repressor complex binds a chromosomal repeat deleted in dystrophic muscle
-
1:CAS:528:DC%2BD38Xmtl2rsrc%3D 12176321
-
Gabellini D, Green MR, Tupler R (2002) Inappropriate gene activation in FSHD: a repressor complex binds a chromosomal repeat deleted in dystrophic muscle. Cell 110:339-348
-
(2002)
Cell
, vol.110
, pp. 339-348
-
-
Gabellini, D.1
Green, M.R.2
Tupler, R.3
-
10
-
-
84875149194
-
Regulation of nucleosome dynamics by histone modifications
-
1:CAS:528:DC%2BC3sXjsFOnsbg%3D 23463310
-
Zentner GE, Henikoff S (2013) Regulation of nucleosome dynamics by histone modifications. Nat Struct Mol Biol 20:259-266
-
(2013)
Nat Struct Mol Biol
, vol.20
, pp. 259-266
-
-
Zentner, G.E.1
Henikoff, S.2
-
11
-
-
0034632829
-
Regulation of chromatin structure by site-specific histone H3 methyltransferases
-
1:CAS:528:DC%2BD3cXmtFegs7s%3D 10949293
-
Rea S, Eisenhaber F, O'Carroll D, Strahl BD, Sun ZW, Schmid M, Opravil S, Mechtler K, Ponting CP, Allis CD et al (2000) Regulation of chromatin structure by site-specific histone H3 methyltransferases. Nature 406:593-599
-
(2000)
Nature
, vol.406
, pp. 593-599
-
-
Rea, S.1
Eisenhaber, F.2
O'Carroll, D.3
Strahl, B.D.4
Sun, Z.W.5
Schmid, M.6
Opravil, S.7
Mechtler, K.8
Ponting, C.P.9
Allis, C.D.10
-
12
-
-
0035815360
-
Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly
-
1:CAS:528:DC%2BD3MXis1Grt78%3D 11283354
-
Nakayama J, Rice JC, Strahl BD, Allis CD, Grewal SI (2001) Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly. Science 292:110-113
-
(2001)
Science
, vol.292
, pp. 110-113
-
-
Nakayama, J.1
Rice, J.C.2
Strahl, B.D.3
Allis, C.D.4
Grewal, S.I.5
-
13
-
-
0034839973
-
Highly specific antibodies determine histone acetylation site usage in yeast heterochromatin and euchromatin
-
1:CAS:528:DC%2BD3MXmvFWgt70%3D 11545749
-
Suka N, Suka Y, Carmen AA, Wu J, Grunstein M (2001) Highly specific antibodies determine histone acetylation site usage in yeast heterochromatin and euchromatin. Mol Cell 8:473-479
-
(2001)
Mol Cell
, vol.8
, pp. 473-479
-
-
Suka, N.1
Suka, Y.2
Carmen, A.A.3
Wu, J.4
Grunstein, M.5
-
14
-
-
32444434989
-
Histone H4-K16 acetylation controls chromatin structure and protein interactions
-
1:CAS:528:DC%2BD28XhtFylsLY%3D 16469925
-
Shogren-Knaak M, Ishii H, Sun JM, Pazin MJ, Davie JR, Peterson CL (2006) Histone H4-K16 acetylation controls chromatin structure and protein interactions. Science 311:844-847
-
(2006)
Science
, vol.311
, pp. 844-847
-
-
Shogren-Knaak, M.1
Ishii, H.2
Sun, J.M.3
Pazin, M.J.4
Davie, J.R.5
Peterson, C.L.6
-
15
-
-
77953973940
-
Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes
-
1:CAS:528:DC%2BC3cXhtV2qsLnI 2926606 20385584
-
Pasini D, Malatesta M, Jung HR, Walfridsson J, Willer A, Olsson L, Skotte J, Wutz A, Porse B, Jensen ON et al (2010) Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes. Nucleic Acids Res 38:4958-4969
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 4958-4969
-
-
Pasini, D.1
Malatesta, M.2
Jung, H.R.3
Walfridsson, J.4
Willer, A.5
Olsson, L.6
Skotte, J.7
Wutz, A.8
Porse, B.9
Jensen, O.N.10
-
16
-
-
84878944044
-
Readout of epigenetic modifications
-
1:CAS:528:DC%2BC3sXhtFOqsrzN 23642229
-
Patel DJ, Wang Z (2013) Readout of epigenetic modifications. Annu Rev Biochem 82:81-118
-
(2013)
Annu Rev Biochem
, vol.82
, pp. 81-118
-
-
Patel, D.J.1
Wang, Z.2
-
17
-
-
0035282458
-
Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain
-
1:CAS:528:DC%2BD3MXhvVSltrY%3D 11242054
-
Bannister AJ, Zegerman P, Partridge JF, Miska EA, Thomas JO, Allshire RC, Kouzarides T (2001) Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain. Nature 410:120-124
-
(2001)
Nature
, vol.410
, pp. 120-124
-
-
Bannister, A.J.1
Zegerman, P.2
Partridge, J.F.3
Miska, E.A.4
Thomas, J.O.5
Allshire, R.C.6
Kouzarides, T.7
-
18
-
-
0035282573
-
Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins
-
1:CAS:528:DC%2BD3MXhvVSltr8%3D 11242053
-
Lachner M, O'Carroll D, Rea S, Mechtler K, Jenuwein T (2001) Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins. Nature 410:116-120
-
(2001)
Nature
, vol.410
, pp. 116-120
-
-
Lachner, M.1
O'Carroll, D.2
Rea, S.3
Mechtler, K.4
Jenuwein, T.5
-
19
-
-
33845755946
-
Heterochromatin revisited
-
1:CAS:528:DC%2BD28Xhtlakt7fO 17173056
-
Grewal SI, Jia S (2007) Heterochromatin revisited. Nat Rev Genet 8:35-46
-
(2007)
Nat Rev Genet
, vol.8
, pp. 35-46
-
-
Grewal, S.I.1
Jia, S.2
-
20
-
-
84895801889
-
Genomic patterns and context specific interpretation of DNA methylation
-
Baubec T, Schubeler D (2014) Genomic patterns and context specific interpretation of DNA methylation. Curr Opin Genet Dev 25C:85-92
-
(2014)
Curr Opin Genet Dev
, vol.25
, pp. 85-92
-
-
Baubec, T.1
Schubeler, D.2
-
21
-
-
0042528729
-
Heterochromatin and epigenetic control of gene expression
-
1:CAS:528:DC%2BD3sXmtVGqsLk%3D 12907790
-
Grewal SI, Moazed D (2003) Heterochromatin and epigenetic control of gene expression. Science 301:798-802
-
(2003)
Science
, vol.301
, pp. 798-802
-
-
Grewal, S.I.1
Moazed, D.2
-
22
-
-
0037636027
-
The establishment, inheritance, and function of silenced chromatin in Saccharomyces cerevisiae
-
1:CAS:528:DC%2BD3sXntFSgtb8%3D 12676793
-
Rusche LN, Kirchmaier AL, Rine J (2003) The establishment, inheritance, and function of silenced chromatin in Saccharomyces cerevisiae. Annu Rev Biochem 72:481-516
-
(2003)
Annu Rev Biochem
, vol.72
, pp. 481-516
-
-
Rusche, L.N.1
Kirchmaier, A.L.2
Rine, J.3
-
23
-
-
33748805480
-
Spreading of silent chromatin: Inaction at a distance
-
1:CAS:528:DC%2BD28Xps1ahsb4%3D 16983375
-
Talbert PB, Henikoff S (2006) Spreading of silent chromatin: inaction at a distance. Nat Rev Genet 7:793-803
-
(2006)
Nat Rev Genet
, vol.7
, pp. 793-803
-
-
Talbert, P.B.1
Henikoff, S.2
-
24
-
-
80052009948
-
Mechanisms for the inheritance of chromatin states
-
1:CAS:528:DC%2BC3MXhtVKjsb%2FJ 3244757 21854979
-
Moazed D (2011) Mechanisms for the inheritance of chromatin states. Cell 146:510-518
-
(2011)
Cell
, vol.146
, pp. 510-518
-
-
Moazed, D.1
-
25
-
-
84881238330
-
SIR proteins and the assembly of silent chromatin in budding yeast
-
1:CAS:528:DC%2BC2cXhsFOitg%3D%3D 24016189
-
Kueng S, Oppikofer M, Gasser SM (2013) SIR proteins and the assembly of silent chromatin in budding yeast. Annu Rev Genet 47:275-306
-
(2013)
Annu Rev Genet
, vol.47
, pp. 275-306
-
-
Kueng, S.1
Oppikofer, M.2
Gasser, S.M.3
-
26
-
-
0034677535
-
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
-
1:CAS:528:DC%2BD3cXhsVWiurY%3D 10693811
-
Imai S, Armstrong CM, Kaeberlein M, Guarente L (2000) Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature 403:795-800
-
(2000)
Nature
, vol.403
, pp. 795-800
-
-
Imai, S.1
Armstrong, C.M.2
Kaeberlein, M.3
Guarente, L.4
-
27
-
-
0034705129
-
The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases
-
1:CAS:528:DC%2BD3cXjvFaktL8%3D 18515 10811920
-
Landry J, Sutton A, Tafrov ST, Heller RC, Stebbins J, Pillus L, Sternglanz R (2000) The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases. Proc Natl Acad Sci USA 97:5807-5811
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 5807-5811
-
-
Landry, J.1
Sutton, A.2
Tafrov, S.T.3
Heller, R.C.4
Stebbins, J.5
Pillus, L.6
Sternglanz, R.7
-
28
-
-
0035895275
-
Coupling of histone deacetylation to NAD breakdown by the yeast silencing protein Sir2: Evidence for acetyl transfer from substrate to an NAD breakdown product
-
1:CAS:528:DC%2BD3MXnslKjug%3D%3D 14600 11134535
-
Tanny JC, Moazed D (2001) Coupling of histone deacetylation to NAD breakdown by the yeast silencing protein Sir2: evidence for acetyl transfer from substrate to an NAD breakdown product. Proc Natl Acad Sci USA 98:415-420
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 415-420
-
-
Tanny, J.C.1
Moazed, D.2
-
29
-
-
0036843170
-
Chromosomal gradient of histone acetylation established by Sas2p and Sir2p functions as a shield against gene silencing
-
12410229
-
Kimura A, Umehara T, Horikoshi M (2002) Chromosomal gradient of histone acetylation established by Sas2p and Sir2p functions as a shield against gene silencing. Nat Genet 32:370-377
-
(2002)
Nat Genet
, vol.32
, pp. 370-377
-
-
Kimura, A.1
Umehara, T.2
Horikoshi, M.3
-
30
-
-
0028919756
-
Histone H3 and H4N-termini interact with SIR3 and SIR4 proteins: A molecular model for the formation of heterochromatin in yeast
-
1:CAS:528:DyaK2MXktV2itrw%3D 7867066
-
Hecht A, Laroche T, Strahl-Bolsinger S, Gasser SM, Grunstein M (1995) Histone H3 and H4N-termini interact with SIR3 and SIR4 proteins: a molecular model for the formation of heterochromatin in yeast. Cell 80:583-592
-
(1995)
Cell
, vol.80
, pp. 583-592
-
-
Hecht, A.1
Laroche, T.2
Strahl-Bolsinger, S.3
Gasser, S.M.4
Grunstein, M.5
-
31
-
-
19344377042
-
Assembly of the SIR complex and its regulation by O-acetyl-ADP-ribose, a product of NAD-dependent histone deacetylation
-
1:CAS:528:DC%2BD2MXkslels7Y%3D 15907466
-
Liou GG, Tanny JC, Kruger RG, Walz T, Moazed D (2005) Assembly of the SIR complex and its regulation by O-acetyl-ADP-ribose, a product of NAD-dependent histone deacetylation. Cell 121:515-527
-
(2005)
Cell
, vol.121
, pp. 515-527
-
-
Liou, G.G.1
Tanny, J.C.2
Kruger, R.G.3
Walz, T.4
Moazed, D.5
-
32
-
-
37349033583
-
Role of the conserved Sir3-BAH domain in nucleosome binding and silent chromatin assembly
-
1:CAS:528:DC%2BD1cXksFyitg%3D%3D 18158899
-
Onishi M, Liou GG, Buchberger JR, Walz T, Moazed D (2007) Role of the conserved Sir3-BAH domain in nucleosome binding and silent chromatin assembly. Mol Cell 28:1015-1028
-
(2007)
Mol Cell
, vol.28
, pp. 1015-1028
-
-
Onishi, M.1
Liou, G.G.2
Buchberger, J.R.3
Walz, T.4
Moazed, D.5
-
33
-
-
0037097940
-
Rap1-Sir4 binding independent of other Sir, yKu, or histone interactions initiates the assembly of telomeric heterochromatin in yeast
-
1:CAS:528:DC%2BD38XltVGmtLY%3D 186350 12080091
-
Luo K, Vega-Palas MA, Grunstein M (2002) Rap1-Sir4 binding independent of other Sir, yKu, or histone interactions initiates the assembly of telomeric heterochromatin in yeast. Genes Dev 16:1528-1539
-
(2002)
Genes Dev
, vol.16
, pp. 1528-1539
-
-
Luo, K.1
Vega-Palas, M.A.2
Grunstein, M.3
-
34
-
-
0032554793
-
Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres
-
1:CAS:528:DyaK1cXjt1Krsbc%3D 9635192
-
Laroche T, Martin SG, Gotta M, Gorham HC, Pryde FE, Louis EJ, Gasser SM (1998) Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres. Curr Biol 8:653-656
-
(1998)
Curr Biol
, vol.8
, pp. 653-656
-
-
Laroche, T.1
Martin, S.G.2
Gotta, M.3
Gorham, H.C.4
Pryde, F.E.5
Louis, E.J.6
Gasser, S.M.7
-
35
-
-
0033533699
-
Yeast Ku protein plays a direct role in telomeric silencing and counteracts inhibition by rif proteins
-
1:CAS:528:DyaK1MXmslensr0%3D 10531008
-
Mishra K, Shore D (1999) Yeast Ku protein plays a direct role in telomeric silencing and counteracts inhibition by rif proteins. Curr Biol 9:1123-1126
-
(1999)
Curr Biol
, vol.9
, pp. 1123-1126
-
-
Mishra, K.1
Shore, D.2
-
36
-
-
0036261650
-
Steps in assembly of silent chromatin in yeast: Sir3-independent binding of a Sir2/Sir4 complex to silencers and role for Sir2-dependent deacetylation
-
1:CAS:528:DC%2BD38XktlSmu78%3D 133845 12024030
-
Hoppe GJ, Tanny JC, Rudner AD, Gerber SA, Danaie S, Gygi SP, Moazed D (2002) Steps in assembly of silent chromatin in yeast: Sir3-independent binding of a Sir2/Sir4 complex to silencers and role for Sir2-dependent deacetylation. Mol Cell Biol 22:4167-4180
-
(2002)
Mol Cell Biol
, vol.22
, pp. 4167-4180
-
-
Hoppe, G.J.1
Tanny, J.C.2
Rudner, A.D.3
Gerber, S.A.4
Danaie, S.5
Gygi, S.P.6
Moazed, D.7
-
37
-
-
0021876965
-
Characterization of a "silencer" in yeast: A DNA sequence with properties opposite to those of a transcriptional enhancer
-
1:CAS:528:DyaL2MXktF2ltb8%3D 3888409
-
Brand AH, Breeden L, Abraham J, Sternglanz R, Nasmyth K (1985) Characterization of a "silencer" in yeast: a DNA sequence with properties opposite to those of a transcriptional enhancer. Cell 41:41-48
-
(1985)
Cell
, vol.41
, pp. 41-48
-
-
Brand, A.H.1
Breeden, L.2
Abraham, J.3
Sternglanz, R.4
Nasmyth, K.5
-
38
-
-
0023644177
-
A yeast silencer contains sequences that can promote autonomous plasmid replication and transcriptional activation
-
1:CAS:528:DyaL1cXltVGjtw%3D%3D 3315230
-
Brand AH, Micklem G, Nasmyth K (1987) A yeast silencer contains sequences that can promote autonomous plasmid replication and transcriptional activation. Cell 51:709-719
-
(1987)
Cell
, vol.51
, pp. 709-719
-
-
Brand, A.H.1
Micklem, G.2
Nasmyth, K.3
-
39
-
-
0023644253
-
Purification and cloning of a DNA binding protein from yeast that binds to both silencer and activator elements
-
1:CAS:528:DyaL1cXhvVWitL0%3D 3315231
-
Shore D, Nasmyth K (1987) Purification and cloning of a DNA binding protein from yeast that binds to both silencer and activator elements. Cell 51:721-732
-
(1987)
Cell
, vol.51
, pp. 721-732
-
-
Shore, D.1
Nasmyth, K.2
-
40
-
-
0027744166
-
Yeast origin recognition complex functions in transcription silencing and DNA replication
-
1:CAS:528:DyaK2cXntVOlsw%3D%3D 8266072
-
Bell SP, Kobayashi R, Stillman B (1993) Yeast origin recognition complex functions in transcription silencing and DNA replication. Science 262:1844-1849
-
(1993)
Science
, vol.262
, pp. 1844-1849
-
-
Bell, S.P.1
Kobayashi, R.2
Stillman, B.3
-
41
-
-
0027787870
-
Origin recognition complex (ORC) in transcriptional silencing and DNA replication in S. Cerevisiae
-
1:CAS:528:DyaK2cXpvVSqsw%3D%3D 8266071
-
Foss M, McNally FJ, Laurenson P, Rine J (1993) Origin recognition complex (ORC) in transcriptional silencing and DNA replication in S. cerevisiae. Science 262:1838-1844
-
(1993)
Science
, vol.262
, pp. 1838-1844
-
-
Foss, M.1
McNally, F.J.2
Laurenson, P.3
Rine, J.4
-
42
-
-
0027184524
-
Silent domains are assembled continuously from the telomere and are defined by promoter distance and strength, and by SIR3 dosage
-
1:CAS:528:DyaK3sXlsFehu7g%3D 8319906
-
Renauld H, Aparicio OM, Zierath PD, Billington BL, Chhablani SK, Gottschling DE (1993) Silent domains are assembled continuously from the telomere and are defined by promoter distance and strength, and by SIR3 dosage. Genes Dev 7:1133-1145
-
(1993)
Genes Dev
, vol.7
, pp. 1133-1145
-
-
Renauld, H.1
Aparicio, O.M.2
Zierath, P.D.3
Billington, B.L.4
Chhablani, S.K.5
Gottschling, D.E.6
-
43
-
-
0029817763
-
Spreading of transcriptional repressor SIR3 from telomeric heterochromatin
-
1:CAS:528:DyaK28XlsV2jtr4%3D 8779721
-
Hecht A, Strahl-Bolsinger S, Grunstein M (1996) Spreading of transcriptional repressor SIR3 from telomeric heterochromatin. Nature 383:92-96
-
(1996)
Nature
, vol.383
, pp. 92-96
-
-
Hecht, A.1
Strahl-Bolsinger, S.2
Grunstein, M.3
-
44
-
-
0031027431
-
SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast
-
1:CAS:528:DyaK2sXlslehsg%3D%3D 9000052
-
Strahl-Bolsinger S, Hecht A, Luo K, Grunstein M (1997) SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast. Genes Dev 11:83-93
-
(1997)
Genes Dev
, vol.11
, pp. 83-93
-
-
Strahl-Bolsinger, S.1
Hecht, A.2
Luo, K.3
Grunstein, M.4
-
45
-
-
0031044789
-
Transcriptional silencing of Ty1 elements in the RDN1 locus of yeast
-
1:CAS:528:DyaK2sXpsVygsA%3D%3D 9009207
-
Bryk M, Banerjee M, Murphy M, Knudsen KE, Garfinkel DJ, Curcio MJ (1997) Transcriptional silencing of Ty1 elements in the RDN1 locus of yeast. Genes Dev 11:255-269
-
(1997)
Genes Dev
, vol.11
, pp. 255-269
-
-
Bryk, M.1
Banerjee, M.2
Murphy, M.3
Knudsen, K.E.4
Garfinkel, D.J.5
Curcio, M.J.6
-
46
-
-
0030831573
-
Direct evidence for SIR2 modulation of chromatin structure in yeast rDNA
-
1:CAS:528:DyaK2sXnslWkt70%3D 1170255 9351831
-
Fritze CE, Verschueren K, Strich R, Easton Esposito R (1997) Direct evidence for SIR2 modulation of chromatin structure in yeast rDNA. EMBO J 16:6495-6509
-
(1997)
EMBO J
, vol.16
, pp. 6495-6509
-
-
Fritze, C.E.1
Verschueren, K.2
Strich, R.3
Easton Esposito, R.4
-
47
-
-
0031056907
-
An unusual form of transcriptional silencing in yeast ribosomal DNA
-
1:CAS:528:DyaK2sXpsVyjuw%3D%3D 9009206
-
Smith JS, Boeke JD (1997) An unusual form of transcriptional silencing in yeast ribosomal DNA. Genes Dev 11:241-254
-
(1997)
Genes Dev
, vol.11
, pp. 241-254
-
-
Smith, J.S.1
Boeke, J.D.2
-
48
-
-
0033574603
-
Net1, a Sir2-associated nucleolar protein required for rDNA silencing and nucleolar integrity
-
1:CAS:528:DyaK1MXislent7s%3D 10219245
-
Straight AF, Shou W, Dowd GJ, Turck CW, Deshaies RJ, Johnson AD, Moazed D (1999) Net1, a Sir2-associated nucleolar protein required for rDNA silencing and nucleolar integrity. Cell 97:245-256
-
(1999)
Cell
, vol.97
, pp. 245-256
-
-
Straight, A.F.1
Shou, W.2
Dowd, G.J.3
Turck, C.W.4
Deshaies, R.J.5
Johnson, A.D.6
Moazed, D.7
-
49
-
-
0031459979
-
Transient inhibition of histone deacetylation alters the structural and functional imprint at fission yeast centromeres
-
1:CAS:528:DyaK1cXjtVKitA%3D%3D 9428524
-
Ekwall K, Olsson T, Turner BM, Cranston G, Allshire RC (1997) Transient inhibition of histone deacetylation alters the structural and functional imprint at fission yeast centromeres. Cell 91:1021-1032
-
(1997)
Cell
, vol.91
, pp. 1021-1032
-
-
Ekwall, K.1
Olsson, T.2
Turner, B.M.3
Cranston, G.4
Allshire, R.C.5
-
50
-
-
3042521583
-
RNAi-independent heterochromatin nucleation by the stress-activated ATF/CREB family proteins
-
1:CAS:528:DC%2BD2cXltVGltb0%3D 15218150
-
Jia S, Noma K, Grewal SI (2004) RNAi-independent heterochromatin nucleation by the stress-activated ATF/CREB family proteins. Science 304:1971-1976
-
(2004)
Science
, vol.304
, pp. 1971-1976
-
-
Jia, S.1
Noma, K.2
Grewal, S.I.3
-
51
-
-
5644230790
-
Regulation of Swi6/HP1-dependent heterochromatin assembly by cooperation of components of the mitogen-activated protein kinase pathway and a histone deacetylase Clr6
-
1:CAS:528:DC%2BD2cXotVOgtrw%3D 15292231
-
Kim HS, Choi ES, Shin JA, Jang YK, Park SD (2004) Regulation of Swi6/HP1-dependent heterochromatin assembly by cooperation of components of the mitogen-activated protein kinase pathway and a histone deacetylase Clr6. J Biol Chem 279:42850-42859
-
(2004)
J Biol Chem
, vol.279
, pp. 42850-42859
-
-
Kim, H.S.1
Choi, E.S.2
Shin, J.A.3
Jang, Y.K.4
Park, S.D.5
-
52
-
-
27144554038
-
Telomere binding protein Taz1 establishes Swi6 heterochromatin independently of RNAi at telomeres
-
1:CAS:528:DC%2BD2MXhtFCjsL7E 16243027
-
Kanoh J, Sadaie M, Urano T, Ishikawa F (2005) Telomere binding protein Taz1 establishes Swi6 heterochromatin independently of RNAi at telomeres. Curr Biol 15:1808-1819
-
(2005)
Curr Biol
, vol.15
, pp. 1808-1819
-
-
Kanoh, J.1
Sadaie, M.2
Urano, T.3
Ishikawa, F.4
-
53
-
-
84887594086
-
Elimination of shelterin components bypasses RNAi for pericentric heterochromatin assembly
-
1:CAS:528:DC%2BC3sXhvVyit7vO 3841737 24240238
-
Tadeo X, Wang J, Kallgren SP, Liu J, Reddy BD, Qiao F, Jia S (2013) Elimination of shelterin components bypasses RNAi for pericentric heterochromatin assembly. Genes Dev 27:2489-2499
-
(2013)
Genes Dev
, vol.27
, pp. 2489-2499
-
-
Tadeo, X.1
Wang, J.2
Kallgren, S.P.3
Liu, J.4
Reddy, B.D.5
Qiao, F.6
Jia, S.7
-
54
-
-
0037072661
-
Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi
-
1:CAS:528:DC%2BD38XmvFGgsr4%3D 12193640
-
Volpe TA, Kidner C, Hall IM, Teng G, Grewal SI, Martienssen RA (2002) Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi. Science 297:1833-1837
-
(2002)
Science
, vol.297
, pp. 1833-1837
-
-
Volpe, T.A.1
Kidner, C.2
Hall, I.M.3
Teng, G.4
Grewal, S.I.5
Martienssen, R.A.6
-
55
-
-
25844480848
-
RNA Pol II subunit Rpb7 promotes centromeric transcription and RNAi-directed chromatin silencing
-
1:CAS:528:DC%2BD2MXhtFais7%2FI 1240039 16204182
-
Djupedal I, Portoso M, Spahr H, Bonilla C, Gustafsson CM, Allshire RC, Ekwall K (2005) RNA Pol II subunit Rpb7 promotes centromeric transcription and RNAi-directed chromatin silencing. Genes Dev 19:2301-2306
-
(2005)
Genes Dev
, vol.19
, pp. 2301-2306
-
-
Djupedal, I.1
Portoso, M.2
Spahr, H.3
Bonilla, C.4
Gustafsson, C.M.5
Allshire, R.C.6
Ekwall, K.7
-
56
-
-
22344434734
-
RNA polymerase II is required for RNAi-dependent heterochromatin assembly
-
1:CAS:528:DC%2BD2MXmtVersLg%3D 15947136
-
Kato H, Goto DB, Martienssen RA, Urano T, Furukawa K, Murakami Y (2005) RNA polymerase II is required for RNAi-dependent heterochromatin assembly. Science 309:467-469
-
(2005)
Science
, vol.309
, pp. 467-469
-
-
Kato, H.1
Goto, D.B.2
Martienssen, R.A.3
Urano, T.4
Furukawa, K.5
Murakami, Y.6
-
57
-
-
38949208022
-
Cell cycle control of centromeric repeat transcription and heterochromatin assembly
-
1:CAS:528:DC%2BD1cXhs1Kns7o%3D 18216783
-
Chen ES, Zhang K, Nicolas E, Cam HP, Zofall M, Grewal SI (2008) Cell cycle control of centromeric repeat transcription and heterochromatin assembly. Nature 451:734-737
-
(2008)
Nature
, vol.451
, pp. 734-737
-
-
Chen, E.S.1
Zhang, K.2
Nicolas, E.3
Cam, H.P.4
Zofall, M.5
Grewal, S.I.6
-
58
-
-
41449089409
-
RNA interference guides histone modification during the S phase of chromosomal replication
-
1:CAS:528:DC%2BD1cXktlGisbk%3D 2408823 18394897
-
Kloc A, Zaratiegui M, Nora E, Martienssen R (2008) RNA interference guides histone modification during the S phase of chromosomal replication. Curr Biol 18:490-495
-
(2008)
Curr Biol
, vol.18
, pp. 490-495
-
-
Kloc, A.1
Zaratiegui, M.2
Nora, E.3
Martienssen, R.4
-
59
-
-
10944248935
-
Two RNAi complexes, RITS and RDRC, physically interact and localize to noncoding centromeric RNAs
-
1:CAS:528:DC%2BD2MXmsFyr 15607976
-
Motamedi MR, Verdel A, Colmenares SU, Gerber SA, Gygi SP, Moazed D (2004) Two RNAi complexes, RITS and RDRC, physically interact and localize to noncoding centromeric RNAs. Cell 119:789-802
-
(2004)
Cell
, vol.119
, pp. 789-802
-
-
Motamedi, M.R.1
Verdel, A.2
Colmenares, S.U.3
Gerber, S.A.4
Gygi, S.P.5
Moazed, D.6
-
60
-
-
11844265935
-
RNA-dependent RNA polymerase is an essential component of a self-enforcing loop coupling heterochromatin assembly to siRNA production
-
1:CAS:528:DC%2BD2MXmtlegsA%3D%3D 544066 15615848
-
Sugiyama T, Cam H, Verdel A, Moazed D, Grewal SI (2005) RNA-dependent RNA polymerase is an essential component of a self-enforcing loop coupling heterochromatin assembly to siRNA production. Proc Natl Acad Sci USA 102:152-157
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 152-157
-
-
Sugiyama, T.1
Cam, H.2
Verdel, A.3
Moazed, D.4
Grewal, S.I.5
-
61
-
-
0942279635
-
RNAi-mediated targeting of heterochromatin by the RITS complex
-
1:CAS:528:DC%2BD2cXmvVKmtQ%3D%3D 3244756 14704433
-
Verdel A, Jia S, Gerber S, Sugiyama T, Gygi S, Grewal SI, Moazed D (2004) RNAi-mediated targeting of heterochromatin by the RITS complex. Science 303:672-676
-
(2004)
Science
, vol.303
, pp. 672-676
-
-
Verdel, A.1
Jia, S.2
Gerber, S.3
Sugiyama, T.4
Gygi, S.5
Grewal, S.I.6
Moazed, D.7
-
62
-
-
33646923128
-
Tethering RITS to a nascent transcript initiates RNAi- and heterochromatin-dependent gene silencing
-
1:CAS:528:DC%2BD28Xls1Shsbc%3D 16751098
-
Buhler M, Verdel A, Moazed D (2006) Tethering RITS to a nascent transcript initiates RNAi- and heterochromatin-dependent gene silencing. Cell 125:873-886
-
(2006)
Cell
, vol.125
, pp. 873-886
-
-
Buhler, M.1
Verdel, A.2
Moazed, D.3
-
63
-
-
33748089700
-
Argonaute slicing is required for heterochromatic silencing and spreading
-
1:CAS:528:DC%2BD28XotlCgtb8%3D 16931764
-
Irvine DV, Zaratiegui M, Tolia NH, Goto DB, Chitwood DH, Vaughn MW, Joshua-Tor L, Martienssen RA (2006) Argonaute slicing is required for heterochromatic silencing and spreading. Science 313:1134-1137
-
(2006)
Science
, vol.313
, pp. 1134-1137
-
-
Irvine, D.V.1
Zaratiegui, M.2
Tolia, N.H.3
Goto, D.B.4
Chitwood, D.H.5
Vaughn, M.W.6
Joshua-Tor, L.7
Martienssen, R.A.8
-
64
-
-
77649105301
-
Stc1: A critical link between RNAi and chromatin modification required for heterochromatin integrity
-
1:CAS:528:DC%2BC3cXlsVSgtro%3D 2875855 20211136
-
Bayne EH, White SA, Kagansky A, Bijos DA, Sanchez-Pulido L, Hoe KL, Kim DU, Park HO, Ponting CP, Rappsilber J et al (2010) Stc1: a critical link between RNAi and chromatin modification required for heterochromatin integrity. Cell 140:666-677
-
(2010)
Cell
, vol.140
, pp. 666-677
-
-
Bayne, E.H.1
White, S.A.2
Kagansky, A.3
Bijos, D.A.4
Sanchez-Pulido, L.5
Hoe, K.L.6
Kim, D.U.7
Park, H.O.8
Ponting, C.P.9
Rappsilber, J.10
-
65
-
-
6344285337
-
A chromodomain protein, Chp1, is required for the establishment of heterochromatin in fission yeast
-
1:CAS:528:DC%2BD2cXnvFCgtL4%3D 522800 15372076
-
Sadaie M, Iida T, Urano T, Nakayama J (2004) A chromodomain protein, Chp1, is required for the establishment of heterochromatin in fission yeast. EMBO J 23:3825-3835
-
(2004)
EMBO J
, vol.23
, pp. 3825-3835
-
-
Sadaie, M.1
Iida, T.2
Urano, T.3
Nakayama, J.4
-
66
-
-
0037183856
-
Establishment and maintenance of a heterochromatin domain
-
1:CAS:528:DC%2BD38XntlWltr4%3D 12215653
-
Hall IM, Shankaranarayana GD, Noma K, Ayoub N, Cohen A, Grewal SI (2002) Establishment and maintenance of a heterochromatin domain. Science 297:2232-2237
-
(2002)
Science
, vol.297
, pp. 2232-2237
-
-
Hall, I.M.1
Shankaranarayana, G.D.2
Noma, K.3
Ayoub, N.4
Cohen, A.5
Grewal, S.I.6
-
67
-
-
0036499971
-
Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing
-
1:CAS:528:DC%2BD38XitFyltrk%3D 125909 11867540
-
Schotta G, Ebert A, Krauss V, Fischer A, Hoffmann J, Rea S, Jenuwein T, Dorn R, Reuter G (2002) Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing. EMBO J 21:1121-1131
-
(2002)
EMBO J
, vol.21
, pp. 1121-1131
-
-
Schotta, G.1
Ebert, A.2
Krauss, V.3
Fischer, A.4
Hoffmann, J.5
Rea, S.6
Jenuwein, T.7
Dorn, R.8
Reuter, G.9
-
68
-
-
15044350409
-
Relationship between histone H3 lysine 9 methylation, transcription repression, and heterochromatin protein 1 recruitment
-
1:CAS:528:DC%2BD2MXis12jtLc%3D 1061631 15767660
-
Stewart MD, Li J, Wong J (2005) Relationship between histone H3 lysine 9 methylation, transcription repression, and heterochromatin protein 1 recruitment. Mol Cell Biol 25:2525-2538
-
(2005)
Mol Cell Biol
, vol.25
, pp. 2525-2538
-
-
Stewart, M.D.1
Li, J.2
Wong, J.3
-
69
-
-
41649092299
-
Roles of the Clr4 methyltransferase complex in nucleation, spreading and maintenance of heterochromatin
-
1:CAS:528:DC%2BD1cXktFyjtb4%3D 18345014
-
Zhang K, Mosch K, Fischle W, Grewal SI (2008) Roles of the Clr4 methyltransferase complex in nucleation, spreading and maintenance of heterochromatin. Nat Struct Mol Biol 15:381-388
-
(2008)
Nat Struct Mol Biol
, vol.15
, pp. 381-388
-
-
Zhang, K.1
Mosch, K.2
Fischle, W.3
Grewal, S.I.4
-
70
-
-
84891665594
-
Division of labor between the chromodomains of HP1 and Suv39 methylase enables coordination of heterochromatin spread
-
1:CAS:528:DC%2BC3sXhtV2rtLzI 3752401 23849629
-
Al-Sady B, Madhani HD, Narlikar GJ (2013) Division of labor between the chromodomains of HP1 and Suv39 methylase enables coordination of heterochromatin spread. Mol Cell 51:80-91
-
(2013)
Mol Cell
, vol.51
, pp. 80-91
-
-
Al-Sady, B.1
Madhani, H.D.2
Narlikar, G.J.3
-
71
-
-
0035839110
-
Transitions in distinct histone H3 methylation patterns at the heterochromatin domain boundaries
-
1:CAS:528:DC%2BD3MXmtVWqtb8%3D 11498594
-
Noma K, Allis CD, Grewal SI (2001) Transitions in distinct histone H3 methylation patterns at the heterochromatin domain boundaries. Science 293:1150-1155
-
(2001)
Science
, vol.293
, pp. 1150-1155
-
-
Noma, K.1
Allis, C.D.2
Grewal, S.I.3
-
72
-
-
0038714132
-
Sir2 regulates histone H3 lysine 9 methylation and heterochromatin assembly in fission yeast
-
1:CAS:528:DC%2BD3sXls1Olsbc%3D 12867036
-
Shankaranarayana GD, Motamedi MR, Moazed D, Grewal SI (2003) Sir2 regulates histone H3 lysine 9 methylation and heterochromatin assembly in fission yeast. Curr Biol 13:1240-1246
-
(2003)
Curr Biol
, vol.13
, pp. 1240-1246
-
-
Shankaranarayana, G.D.1
Motamedi, M.R.2
Moazed, D.3
Grewal, S.I.4
-
73
-
-
84877623602
-
Distinct roles for Sir2 and RNAi in centromeric heterochromatin nucleation, spreading and maintenance
-
1:CAS:528:DC%2BC3sXlsFSgu78%3D 3642681 23572080
-
Buscaino A, Lejeune E, Audergon P, Hamilton G, Pidoux A, Allshire RC (2013) Distinct roles for Sir2 and RNAi in centromeric heterochromatin nucleation, spreading and maintenance. EMBO J 32:1250-1264
-
(2013)
EMBO J
, vol.32
, pp. 1250-1264
-
-
Buscaino, A.1
Lejeune, E.2
Audergon, P.3
Hamilton, G.4
Pidoux, A.5
Allshire, R.C.6
-
74
-
-
84883638441
-
Epe1 recruits BET family bromodomain protein Bdf2 to establish heterochromatin boundaries
-
1:CAS:528:DC%2BC3sXhsFajurrL 3778242 24013502
-
Wang J, Tadeo X, Hou H, Tu PG, Thompson J, Yates JR 3rd, Jia S (2013) Epe1 recruits BET family bromodomain protein Bdf2 to establish heterochromatin boundaries. Genes Dev 27:1886-1902
-
(2013)
Genes Dev
, vol.27
, pp. 1886-1902
-
-
Wang, J.1
Tadeo, X.2
Hou, H.3
Tu, P.G.4
Thompson, J.5
Yates, J.R.6
Jia, S.7
-
75
-
-
26944434789
-
The nucleation and maintenance of heterochromatin by a histone deacetylase in fission yeast
-
1:CAS:528:DC%2BD2MXht1SntrbJ 16246721
-
Yamada T, Fischle W, Sugiyama T, Allis CD, Grewal SI (2005) The nucleation and maintenance of heterochromatin by a histone deacetylase in fission yeast. Mol Cell 20:173-185
-
(2005)
Mol Cell
, vol.20
, pp. 173-185
-
-
Yamada, T.1
Fischle, W.2
Sugiyama, T.3
Allis, C.D.4
Grewal, S.I.5
-
76
-
-
33846703987
-
SHREC, an effector complex for heterochromatic transcriptional silencing
-
1:CAS:528:DC%2BD2sXit1Wlt7c%3D 17289569
-
Sugiyama T, Cam HP, Sugiyama R, Noma K, Zofall M, Kobayashi R, Grewal SI (2007) SHREC, an effector complex for heterochromatic transcriptional silencing. Cell 128:491-504
-
(2007)
Cell
, vol.128
, pp. 491-504
-
-
Sugiyama, T.1
Cam, H.P.2
Sugiyama, R.3
Noma, K.4
Zofall, M.5
Kobayashi, R.6
Grewal, S.I.7
-
77
-
-
57749097725
-
HP1 proteins form distinct complexes and mediate heterochromatic gene silencing by nonoverlapping mechanisms
-
1:CAS:528:DC%2BD1MXjtFGmug%3D%3D 2735125 19111658
-
Motamedi MR, Hong EJ, Li X, Gerber S, Denison C, Gygi S, Moazed D (2008) HP1 proteins form distinct complexes and mediate heterochromatic gene silencing by nonoverlapping mechanisms. Mol Cell 32:778-790
-
(2008)
Mol Cell
, vol.32
, pp. 778-790
-
-
Motamedi, M.R.1
Hong, E.J.2
Li, X.3
Gerber, S.4
Denison, C.5
Gygi, S.6
Moazed, D.7
-
78
-
-
67049100267
-
Diverse roles of HP1 proteins in heterochromatin assembly and functions in fission yeast
-
1:CAS:528:DC%2BD1MXntlyjt7o%3D 2690032 19443688
-
Fischer T, Cui B, Dhakshnamoorthy J, Zhou M, Rubin C, Zofall M, Veenstra TD, Grewal SI (2009) Diverse roles of HP1 proteins in heterochromatin assembly and functions in fission yeast. Proc Natl Acad Sci USA 106:8998-9003
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 8998-9003
-
-
Fischer, T.1
Cui, B.2
Dhakshnamoorthy, J.3
Zhou, M.4
Rubin, C.5
Zofall, M.6
Veenstra, T.D.7
Grewal, S.I.8
-
79
-
-
84876285368
-
A conformational switch in HP1 releases auto-inhibition to drive heterochromatin assembly
-
1:CAS:528:DC%2BC3sXkvFOktr0%3D 3907283 23485968
-
Canzio D, Liao M, Naber N, Pate E, Larson A, Wu S, Marina DB, Garcia JF, Madhani HD, Cooke R et al (2013) A conformational switch in HP1 releases auto-inhibition to drive heterochromatin assembly. Nature 496:377-381
-
(2013)
Nature
, vol.496
, pp. 377-381
-
-
Canzio, D.1
Liao, M.2
Naber, N.3
Pate, E.4
Larson, A.5
Wu, S.6
Marina, D.B.7
Garcia, J.F.8
Madhani, H.D.9
Cooke, R.10
-
80
-
-
79960389332
-
Coordination of DNA replication and histone modification by the Rik1-Dos2 complex
-
1:CAS:528:DC%2BC3MXotlCmt78%3D 3163161 21725325
-
Li F, Martienssen R, Cande WZ (2011) Coordination of DNA replication and histone modification by the Rik1-Dos2 complex. Nature 475:244-248
-
(2011)
Nature
, vol.475
, pp. 244-248
-
-
Li, F.1
Martienssen, R.2
Cande, W.Z.3
-
81
-
-
80455176844
-
RNAi promotes heterochromatic silencing through replication-coupled release of RNA Pol II
-
1:CAS:528:DC%2BC3MXhtlWlurzF 3391703 22002604
-
Zaratiegui M, Castel SE, Irvine DV, Kloc A, Ren J, Li F, de Castro E, Marin L, Chang AY, Goto D et al (2011) RNAi promotes heterochromatic silencing through replication-coupled release of RNA Pol II. Nature 479:135-138
-
(2011)
Nature
, vol.479
, pp. 135-138
-
-
Zaratiegui, M.1
Castel, S.E.2
Irvine, D.V.3
Kloc, A.4
Ren, J.5
Li, F.6
De Castro, E.7
Marin, L.8
Chang, A.Y.9
Goto, D.10
-
82
-
-
0037324675
-
Position-effect variegation and the genetic dissection of chromatin regulation in Drosophila
-
1:CAS:528:DC%2BD3sXnvFam 12524009
-
Schotta G, Ebert A, Dorn R, Reuter G (2003) Position-effect variegation and the genetic dissection of chromatin regulation in Drosophila. Semin Cell Dev Biol 14:67-75
-
(2003)
Semin Cell Dev Biol
, vol.14
, pp. 67-75
-
-
Schotta, G.1
Ebert, A.2
Dorn, R.3
Reuter, G.4
-
83
-
-
70349469565
-
Mechanisms of polycomb gene silencing: Knowns and unknowns
-
1:CAS:528:DC%2BD1MXhtV2qtL%2FO 19738629
-
Simon JA, Kingston RE (2009) Mechanisms of polycomb gene silencing: knowns and unknowns. Nat Rev Mol Cell Biol 10:697-708
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 697-708
-
-
Simon, J.A.1
Kingston, R.E.2
-
84
-
-
0036830642
-
Role of histone H3 lysine 27 methylation in Polycomb-group silencing
-
1:CAS:528:DC%2BD38Xot12rs7g%3D 12351676
-
Cao R, Wang L, Wang H, Xia L, Erdjument-Bromage H, Tempst P, Jones RS, Zhang Y (2002) Role of histone H3 lysine 27 methylation in Polycomb-group silencing. Science 298:1039-1043
-
(2002)
Science
, vol.298
, pp. 1039-1043
-
-
Cao, R.1
Wang, L.2
Wang, H.3
Xia, L.4
Erdjument-Bromage, H.5
Tempst, P.6
Jones, R.S.7
Zhang, Y.8
-
85
-
-
0037131523
-
Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites
-
1:CAS:528:DC%2BD38Xotlahsr8%3D 12408863
-
Czermin B, Melfi R, McCabe D, Seitz V, Imhof A, Pirrotta V (2002) Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites. Cell 111:185-196
-
(2002)
Cell
, vol.111
, pp. 185-196
-
-
Czermin, B.1
Melfi, R.2
McCabe, D.3
Seitz, V.4
Imhof, A.5
Pirrotta, V.6
-
86
-
-
0037111831
-
Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein
-
1:CAS:528:DC%2BD38XovVejsLY%3D 187479 12435631
-
Kuzmichev A, Nishioka K, Erdjument-Bromage H, Tempst P, Reinberg D (2002) Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein. Genes Dev 16:2893-2905
-
(2002)
Genes Dev
, vol.16
, pp. 2893-2905
-
-
Kuzmichev, A.1
Nishioka, K.2
Erdjument-Bromage, H.3
Tempst, P.4
Reinberg, D.5
-
87
-
-
18644383738
-
Histone methyltransferase activity of a Drosophila Polycomb group repressor complex
-
1:CAS:528:DC%2BD38Xotlahsrw%3D 12408864
-
Muller J, Hart CM, Francis NJ, Vargas ML, Sengupta A, Wild B, Miller EL, O'Connor MB, Kingston RE, Simon JA (2002) Histone methyltransferase activity of a Drosophila Polycomb group repressor complex. Cell 111:197-208
-
(2002)
Cell
, vol.111
, pp. 197-208
-
-
Muller, J.1
Hart, C.M.2
Francis, N.J.3
Vargas, M.L.4
Sengupta, A.5
Wild, B.6
Miller, E.L.7
O'Connor, M.B.8
Kingston, R.E.9
Simon, J.A.10
-
88
-
-
0043127085
-
Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains
-
1:CAS:528:DC%2BD3sXmt1Sjt78%3D 196235 12897054
-
Fischle W, Wang Y, Jacobs SA, Kim Y, Allis CD, Khorasanizadeh S (2003) Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains. Genes Dev 17:1870-1881
-
(2003)
Genes Dev
, vol.17
, pp. 1870-1881
-
-
Fischle, W.1
Wang, Y.2
Jacobs, S.A.3
Kim, Y.4
Allis, C.D.5
Khorasanizadeh, S.6
-
89
-
-
0041624288
-
Structural basis for specific binding of Polycomb chromodomain to histone H3 methylated at Lys 27
-
1:CAS:528:DC%2BD3sXmt1Sjtrg%3D 196225 12897052
-
Min J, Zhang Y, Xu RM (2003) Structural basis for specific binding of Polycomb chromodomain to histone H3 methylated at Lys 27. Genes Dev 17:1823-1828
-
(2003)
Genes Dev
, vol.17
, pp. 1823-1828
-
-
Min, J.1
Zhang, Y.2
Xu, R.M.3
-
90
-
-
7244234099
-
Role of histone H2A ubiquitination in Polycomb silencing
-
1:CAS:528:DC%2BD2cXotl2ktrY%3D 15386022
-
Wang H, Wang L, Erdjument-Bromage H, Vidal M, Tempst P, Jones RS, Zhang Y (2004) Role of histone H2A ubiquitination in Polycomb silencing. Nature 431:873-878
-
(2004)
Nature
, vol.431
, pp. 873-878
-
-
Wang, H.1
Wang, L.2
Erdjument-Bromage, H.3
Vidal, M.4
Tempst, P.5
Jones, R.S.6
Zhang, Y.7
-
91
-
-
55549103314
-
A model for transmission of the H3K27me3 epigenetic mark
-
1:CAS:528:DC%2BD1cXhtlais7jK 18931660
-
Hansen KH, Bracken AP, Pasini D, Dietrich N, Gehani SS, Monrad A, Rappsilber J, Lerdrup M, Helin K (2008) A model for transmission of the H3K27me3 epigenetic mark. Nat Cell Biol 10:1291-1300
-
(2008)
Nat Cell Biol
, vol.10
, pp. 1291-1300
-
-
Hansen, K.H.1
Bracken, A.P.2
Pasini, D.3
Dietrich, N.4
Gehani, S.S.5
Monrad, A.6
Rappsilber, J.7
Lerdrup, M.8
Helin, K.9
-
92
-
-
70349952171
-
Role of the polycomb protein EED in the propagation of repressive histone marks
-
1:CAS:528:DC%2BD1MXhtFGjt73N 3772642 19767730
-
Margueron R, Justin N, Ohno K, Sharpe ML, Son J, Drury WJ 3rd, Voigt P, Martin SR, Taylor WR, De Marco V et al (2009) Role of the polycomb protein EED in the propagation of repressive histone marks. Nature 461:762-767
-
(2009)
Nature
, vol.461
, pp. 762-767
-
-
Margueron, R.1
Justin, N.2
Ohno, K.3
Sharpe, M.L.4
Son, J.5
Drury, W.J.6
Voigt, P.7
Martin, S.R.8
Taylor, W.R.9
De Marco, V.10
-
93
-
-
33745225872
-
Genome-wide analysis of Polycomb targets in Drosophila melanogaster
-
1:CAS:528:DC%2BD28XltVOhurc%3D 16732288
-
Schwartz YB, Kahn TG, Nix DA, Li XY, Bourgon R, Biggin M, Pirrotta V (2006) Genome-wide analysis of Polycomb targets in Drosophila melanogaster. Nat Genet 38:700-705
-
(2006)
Nat Genet
, vol.38
, pp. 700-705
-
-
Schwartz, Y.B.1
Kahn, T.G.2
Nix, D.A.3
Li, X.Y.4
Bourgon, R.5
Biggin, M.6
Pirrotta, V.7
-
94
-
-
33845799903
-
Polycomb silencing mechanisms and the management of genomic programmes
-
1:CAS:528:DC%2BD28Xhtlakt7fM 17173055
-
Schwartz YB, Pirrotta V (2007) Polycomb silencing mechanisms and the management of genomic programmes. Nat Rev Genet 8:9-22
-
(2007)
Nat Rev Genet
, vol.8
, pp. 9-22
-
-
Schwartz, Y.B.1
Pirrotta, V.2
-
95
-
-
77649083650
-
The DMM complex prevents spreading of DNA methylation from transposons to nearby genes in Neurospora crassa
-
1:CAS:528:DC%2BC3cXjtFaitbc%3D 2827840 20139222
-
Honda S, Lewis ZA, Huarte M, Cho LY, David LL, Shi Y, Selker EU (2010) The DMM complex prevents spreading of DNA methylation from transposons to nearby genes in Neurospora crassa. Genes Dev 24:443-454
-
(2010)
Genes Dev
, vol.24
, pp. 443-454
-
-
Honda, S.1
Lewis, Z.A.2
Huarte, M.3
Cho, L.Y.4
David, L.L.5
Shi, Y.6
Selker, E.U.7
-
96
-
-
3042733279
-
Partition of distinct chromosomal regions: Negotiable border and fixed border
-
1:CAS:528:DC%2BD2cXlsVOjtrc%3D 15189444
-
Kimura A, Horikoshi M (2004) Partition of distinct chromosomal regions: negotiable border and fixed border. Genes Cells 9:499-508
-
(2004)
Genes Cells
, vol.9
, pp. 499-508
-
-
Kimura, A.1
Horikoshi, M.2
-
97
-
-
0036842129
-
Sir2p and Sas2p opposingly regulate acetylation of yeast histone H4 lysine16 and spreading of heterochromatin
-
1:CAS:528:DC%2BD38Xot1Kls7k%3D 12379856
-
Suka N, Luo K, Grunstein M (2002) Sir2p and Sas2p opposingly regulate acetylation of yeast histone H4 lysine16 and spreading of heterochromatin. Nat Genet 32:378-383
-
(2002)
Nat Genet
, vol.32
, pp. 378-383
-
-
Suka, N.1
Luo, K.2
Grunstein, M.3
-
98
-
-
0037291760
-
Bromodomains mediate an acetyl-histone encoded antisilencing function at heterochromatin boundaries
-
1:CAS:528:DC%2BD3sXit1Wgs70%3D 12620225
-
Ladurner AG, Inouye C, Jain R, Tjian R (2003) Bromodomains mediate an acetyl-histone encoded antisilencing function at heterochromatin boundaries. Mol Cell 11:365-376
-
(2003)
Mol Cell
, vol.11
, pp. 365-376
-
-
Ladurner, A.G.1
Inouye, C.2
Jain, R.3
Tjian, R.4
-
99
-
-
0037423930
-
Conserved histone variant H2A.Z protects euchromatin from the ectopic spread of silent heterochromatin
-
1:CAS:528:DC%2BD3sXitFyku7o%3D 12628191
-
Meneghini MD, Wu M, Madhani HD (2003) Conserved histone variant H2A.Z protects euchromatin from the ectopic spread of silent heterochromatin. Cell 112:725-736
-
(2003)
Cell
, vol.112
, pp. 725-736
-
-
Meneghini, M.D.1
Wu, M.2
Madhani, H.D.3
-
100
-
-
84880926337
-
Single cell visualization of yeast gene expression shows correlation of epigenetic switching between multiple heterochromatic regions through multiple generations
-
1:CAS:528:DC%2BC3sXht1ygu7nO 3699475 23843746
-
Mano Y, Kobayashi TJ, Nakayama J, Uchida H, Oki M (2013) Single cell visualization of yeast gene expression shows correlation of epigenetic switching between multiple heterochromatic regions through multiple generations. PLoS Biol 11:e1001601
-
(2013)
PLoS Biol
, vol.11
, pp. 1001601
-
-
Mano, Y.1
Kobayashi, T.J.2
Nakayama, J.3
Uchida, H.4
Oki, M.5
-
101
-
-
10044244766
-
Su(var) genes regulate the balance between euchromatin and heterochromatin in Drosophila
-
1:CAS:528:DC%2BD2cXhtFShu7bM 534657 15574598
-
Ebert A, Schotta G, Lein S, Kubicek S, Krauss V, Jenuwein T, Reuter G (2004) Su(var) genes regulate the balance between euchromatin and heterochromatin in Drosophila. Genes Dev 18:2973-2983
-
(2004)
Genes Dev
, vol.18
, pp. 2973-2983
-
-
Ebert, A.1
Schotta, G.2
Lein, S.3
Kubicek, S.4
Krauss, V.5
Jenuwein, T.6
Reuter, G.7
-
102
-
-
47349112662
-
SiRNA-mediated heterochromatin establishment requires HP1 and is associated with antisense transcription
-
1:CAS:528:DC%2BD1cXpsFOgtL4%3D 2575423 18657501
-
Iida T, Nakayama J, Moazed D (2008) siRNA-mediated heterochromatin establishment requires HP1 and is associated with antisense transcription. Mol Cell 31:178-189
-
(2008)
Mol Cell
, vol.31
, pp. 178-189
-
-
Iida, T.1
Nakayama, J.2
Moazed, D.3
-
103
-
-
67649939154
-
Synthetic heterochromatin bypasses RNAi and centromeric repeats to establish functional centromeres
-
1:CAS:528:DC%2BD1MXnsFOmtrc%3D 2949999 19556509
-
Kagansky A, Folco HD, Almeida R, Pidoux AL, Boukaba A, Simmer F, Urano T, Hamilton GL, Allshire RC (2009) Synthetic heterochromatin bypasses RNAi and centromeric repeats to establish functional centromeres. Science 324:1716-1719
-
(2009)
Science
, vol.324
, pp. 1716-1719
-
-
Kagansky, A.1
Folco, H.D.2
Almeida, R.3
Pidoux, A.L.4
Boukaba, A.5
Simmer, F.6
Urano, T.7
Hamilton, G.L.8
Allshire, R.C.9
-
104
-
-
0034724537
-
A chromodomain protein, Swi6, performs imprinting functions in fission yeast during mitosis and meiosis
-
1:CAS:528:DC%2BD3cXjtFSrtLs%3D 10847685
-
Nakayama J, Klar AJ, Grewal SI (2000) A chromodomain protein, Swi6, performs imprinting functions in fission yeast during mitosis and meiosis. Cell 101:307-317
-
(2000)
Cell
, vol.101
, pp. 307-317
-
-
Nakayama, J.1
Klar, A.J.2
Grewal, S.I.3
-
105
-
-
0029746494
-
Evidence for silencing compartments within the yeast nucleus: A role for telomere proximity and Sir protein concentration in silencer-mediated repression
-
1:CAS:528:DyaK28Xks1OntL8%3D 8698239
-
Maillet L, Boscheron C, Gotta M, Marcand S, Gilson E, Gasser SM (1996) Evidence for silencing compartments within the yeast nucleus: a role for telomere proximity and Sir protein concentration in silencer-mediated repression. Genes Dev 10:1796-1811
-
(1996)
Genes Dev
, vol.10
, pp. 1796-1811
-
-
Maillet, L.1
Boscheron, C.2
Gotta, M.3
Marcand, S.4
Gilson, E.5
Gasser, S.M.6
-
106
-
-
0029741576
-
Silencing of genes at nontelomeric sites in yeast is controlled by sequestration of silencing factors at telomeres by Rap 1 protein
-
1:CAS:528:DyaK28XjslSgsLs%3D 8647429
-
Marcand S, Buck SW, Moretti P, Gilson E, Shore D (1996) Silencing of genes at nontelomeric sites in yeast is controlled by sequestration of silencing factors at telomeres by Rap 1 protein. Genes Dev 10:1297-1309
-
(1996)
Genes Dev
, vol.10
, pp. 1297-1309
-
-
Marcand, S.1
Buck, S.W.2
Moretti, P.3
Gilson, E.4
Shore, D.5
-
107
-
-
18844402900
-
Spontaneous rDNA copy number variation modulates Sir2 levels and epigenetic gene silencing
-
1:CAS:528:DC%2BD2MXksFKnu78%3D 1132006 15905408
-
Michel AH, Kornmann B, Dubrana K, Shore D (2005) Spontaneous rDNA copy number variation modulates Sir2 levels and epigenetic gene silencing. Genes Dev 19:1199-1210
-
(2005)
Genes Dev
, vol.19
, pp. 1199-1210
-
-
Michel, A.H.1
Kornmann, B.2
Dubrana, K.3
Shore, D.4
-
108
-
-
63849287611
-
The functional importance of telomere clustering: Global changes in gene expression result from SIR factor dispersion
-
1:CAS:528:DC%2BD1MXksVKns7c%3D 2665780 19179643
-
Taddei A, Van Houwe G, Nagai S, Erb I, van Nimwegen E, Gasser SM (2009) The functional importance of telomere clustering: global changes in gene expression result from SIR factor dispersion. Genome Res 19:611-625
-
(2009)
Genome Res
, vol.19
, pp. 611-625
-
-
Taddei, A.1
Van Houwe, G.2
Nagai, S.3
Erb, I.4
Van Nimwegen, E.5
Gasser, S.M.6
-
109
-
-
0035254535
-
RNA polymerase III and RNA polymerase II promoter complexes are heterochromatin barriers in Saccharomyces cerevisiae
-
1:CAS:528:DC%2BD3MXitFGqt7s%3D 133458 11157758
-
Donze D, Kamakaka RT (2001) RNA polymerase III and RNA polymerase II promoter complexes are heterochromatin barriers in Saccharomyces cerevisiae. EMBO J 20:520-531
-
(2001)
EMBO J
, vol.20
, pp. 520-531
-
-
Donze, D.1
Kamakaka, R.T.2
-
110
-
-
1342346506
-
Barrier proteins remodel and modify chromatin to restrict silenced domains
-
1:CAS:528:DC%2BD2cXhvVWgtL4%3D 350565 14966276
-
Oki M, Valenzuela L, Chiba T, Ito T, Kamakaka RT (2004) Barrier proteins remodel and modify chromatin to restrict silenced domains. Mol Cell Biol 24:1956-1967
-
(2004)
Mol Cell Biol
, vol.24
, pp. 1956-1967
-
-
Oki, M.1
Valenzuela, L.2
Chiba, T.3
Ito, T.4
Kamakaka, R.T.5
-
111
-
-
24044461066
-
Barrier function at HMR
-
1:CAS:528:DC%2BD2MXhtVSkurvI 16137626
-
Oki M, Kamakaka RT (2005) Barrier function at HMR. Mol Cell 19:707-716
-
(2005)
Mol Cell
, vol.19
, pp. 707-716
-
-
Oki, M.1
Kamakaka, R.T.2
-
112
-
-
34047248915
-
S. Pombe LSD1 homologs regulate heterochromatin propagation and euchromatic gene transcription
-
1:CAS:528:DC%2BD2sXkvFSrtrk%3D 17434129
-
Lan F, Zaratiegui M, Villen J, Vaughn MW, Verdel A, Huarte M, Shi Y, Gygi SP, Moazed D, Martienssen RA (2007) S. pombe LSD1 homologs regulate heterochromatin propagation and euchromatic gene transcription. Mol Cell 26:89-101
-
(2007)
Mol Cell
, vol.26
, pp. 89-101
-
-
Lan, F.1
Zaratiegui, M.2
Villen, J.3
Vaughn, M.W.4
Verdel, A.5
Huarte, M.6
Shi, Y.7
Gygi, S.P.8
Moazed, D.9
Martienssen, R.A.10
-
113
-
-
11144332565
-
Histone demethylation mediated by the nuclear amine oxidase homolog LSD1
-
1:CAS:528:DC%2BD2MXltlSitg%3D%3D 15620353
-
Shi Y, Lan F, Matson C, Mulligan P, Whetstine JR, Cole PA, Casero RA (2004) Histone demethylation mediated by the nuclear amine oxidase homolog LSD1. Cell 119:941-953
-
(2004)
Cell
, vol.119
, pp. 941-953
-
-
Shi, Y.1
Lan, F.2
Matson, C.3
Mulligan, P.4
Whetstine, J.R.5
Cole, P.A.6
Casero, R.A.7
-
114
-
-
24144462170
-
LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription
-
1:CAS:528:DC%2BD2MXpvFOrtL4%3D 16079795
-
Metzger E, Wissmann M, Yin N, Muller JM, Schneider R, Peters AH, Gunther T, Buettner R, Schule R (2005) LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription. Nature 437:436-439
-
(2005)
Nature
, vol.437
, pp. 436-439
-
-
Metzger, E.1
Wissmann, M.2
Yin, N.3
Muller, J.M.4
Schneider, R.5
Peters, A.H.6
Gunther, T.7
Buettner, R.8
Schule, R.9
-
115
-
-
8644240108
-
Recruitment of histone modifications by USF proteins at a vertebrate barrier element
-
1:CAS:528:DC%2BD2cXhtVWhtr%2FK 15525517
-
West AG, Huang S, Gaszner M, Litt MD, Felsenfeld G (2004) Recruitment of histone modifications by USF proteins at a vertebrate barrier element. Mol Cell 16:453-463
-
(2004)
Mol Cell
, vol.16
, pp. 453-463
-
-
West, A.G.1
Huang, S.2
Gaszner, M.3
Litt, M.D.4
Felsenfeld, G.5
-
116
-
-
17644367887
-
Proteomic and genomic characterization of chromatin complexes at a boundary
-
1:CAS:528:DC%2BD2MXjtlOrsL4%3D 2171912 15824130
-
Tackett AJ, Dilworth DJ, Davey MJ, O'Donnell M, Aitchison JD, Rout MP, Chait BT (2005) Proteomic and genomic characterization of chromatin complexes at a boundary. J Cell Biol 169:35-47
-
(2005)
J Cell Biol
, vol.169
, pp. 35-47
-
-
Tackett, A.J.1
Dilworth, D.J.2
Davey, M.J.3
O'Donnell, M.4
Aitchison, J.D.5
Rout, M.P.6
Chait, B.T.7
-
117
-
-
32544455270
-
Multiple bromodomain genes are involved in restricting the spread of heterochromatic silencing at the Saccharomyces cerevisiae HMR-tRNA boundary
-
1:CAS:528:DC%2BD28Xjs1Klsw%3D%3D 1456849 16079223
-
Jambunathan N, Martinez AW, Robert EC, Agochukwu NB, Ibos ME, Dugas SL, Donze D (2005) Multiple bromodomain genes are involved in restricting the spread of heterochromatic silencing at the Saccharomyces cerevisiae HMR-tRNA boundary. Genetics 171:913-922
-
(2005)
Genetics
, vol.171
, pp. 913-922
-
-
Jambunathan, N.1
Martinez, A.W.2
Robert, E.C.3
Agochukwu, N.B.4
Ibos, M.E.5
Dugas, S.L.6
Donze, D.7
-
118
-
-
68849107666
-
A noncanonical bromodomain in the AAA ATPase protein Yta7 directs chromosomal positioning and barrier chromatin activity
-
1:CAS:528:DC%2BD1MXhtFWgs7%2FF 2725702 19581291
-
Gradolatto A, Smart SK, Byrum S, Blair LP, Rogers RS, Kolar EA, Lavender H, Larson SK, Aitchison JD, Taverna SD et al (2009) A noncanonical bromodomain in the AAA ATPase protein Yta7 directs chromosomal positioning and barrier chromatin activity. Mol Cell Biol 29:4604-4611
-
(2009)
Mol Cell Biol
, vol.29
, pp. 4604-4611
-
-
Gradolatto, A.1
Smart, S.K.2
Byrum, S.3
Blair, L.P.4
Rogers, R.S.5
Kolar, E.A.6
Lavender, H.7
Larson, S.K.8
Aitchison, J.D.9
Taverna, S.D.10
-
119
-
-
33744552663
-
Swi6/HP1 recruits a JmjC domain protein to facilitate transcription of heterochromatic repeats
-
1:CAS:528:DC%2BD28XmtFSru7o%3D 16762840
-
Zofall M, Grewal SI (2006) Swi6/HP1 recruits a JmjC domain protein to facilitate transcription of heterochromatic repeats. Mol Cell 22:681-692
-
(2006)
Mol Cell
, vol.22
, pp. 681-692
-
-
Zofall, M.1
Grewal, S.I.2
-
120
-
-
78650964584
-
The Cul4-Ddb1(Cdt)(2) ubiquitin ligase inhibits invasion of a boundary-associated antisilencing factor into heterochromatin
-
1:CAS:528:DC%2BC3MXksFGjuw%3D%3D 3645473 21215368
-
Braun S, Garcia JF, Rowley M, Rougemaille M, Shankar S, Madhani HD (2011) The Cul4-Ddb1(Cdt)(2) ubiquitin ligase inhibits invasion of a boundary-associated antisilencing factor into heterochromatin. Cell 144:41-54
-
(2011)
Cell
, vol.144
, pp. 41-54
-
-
Braun, S.1
Garcia, J.F.2
Rowley, M.3
Rougemaille, M.4
Shankar, S.5
Madhani, H.D.6
-
121
-
-
1342282911
-
Formation of boundaries of transcriptionally silent chromatin by nucleosome-excluding structures
-
1:CAS:528:DC%2BD2cXhvVWgtbo%3D 350542 14966290
-
Bi X, Yu Q, Sandmeier JJ, Zou Y (2004) Formation of boundaries of transcriptionally silent chromatin by nucleosome-excluding structures. Mol Cell Biol 24:2118-2131
-
(2004)
Mol Cell Biol
, vol.24
, pp. 2118-2131
-
-
Bi, X.1
Yu, Q.2
Sandmeier, J.J.3
Zou, Y.4
-
122
-
-
0033121285
-
UASrpg can function as a heterochromatin boundary element in yeast
-
1:CAS:528:DyaK1MXjt1yiu78%3D 316950 10323861
-
Bi X, Broach JR (1999) UASrpg can function as a heterochromatin boundary element in yeast. Genes Dev 13:1089-1101
-
(1999)
Genes Dev
, vol.13
, pp. 1089-1101
-
-
Bi, X.1
Broach, J.R.2
-
123
-
-
31144445949
-
Dynamic regulation of replication independent deposition of histone H3 in fission yeast
-
1:CAS:528:DC%2BD28XisFKqsw%3D%3D 1316113 16361268
-
Choi ES, Shin JA, Kim HS, Jang YK (2005) Dynamic regulation of replication independent deposition of histone H3 in fission yeast. Nucleic Acids Res 33:7102-7110
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 7102-7110
-
-
Choi, E.S.1
Shin, J.A.2
Kim, H.S.3
Jang, Y.K.4
-
124
-
-
85027919146
-
HDAC-mediated suppression of histone turnover promotes epigenetic stability of heterochromatin
-
3661211 23604080
-
Aygun O, Mehta S, Grewal SI (2013) HDAC-mediated suppression of histone turnover promotes epigenetic stability of heterochromatin. Nat Struct Mol Biol 20:547-554
-
(2013)
Nat Struct Mol Biol
, vol.20
, pp. 547-554
-
-
Aygun, O.1
Mehta, S.2
Grewal, S.I.3
-
125
-
-
33947137710
-
Dynamics of replication-independent histone turnover in budding yeast
-
1:CAS:528:DC%2BD2sXisVKrsrs%3D 17347438
-
Dion MF, Kaplan T, Kim M, Buratowski S, Friedman N, Rando OJ (2007) Dynamics of replication-independent histone turnover in budding yeast. Science 315:1405-1408
-
(2007)
Science
, vol.315
, pp. 1405-1408
-
-
Dion, M.F.1
Kaplan, T.2
Kim, M.3
Buratowski, S.4
Friedman, N.5
Rando, O.J.6
-
126
-
-
33947138617
-
Drosophila GAGA factor directs histone H3.3 replacement that prevents the heterochromatin spreading
-
1:CAS:528:DC%2BD2sXjsVSqtLY%3D 1820897 17344416
-
Nakayama T, Nishioka K, Dong YX, Shimojima T, Hirose S (2007) Drosophila GAGA factor directs histone H3.3 replacement that prevents the heterochromatin spreading. Genes Dev 21:552-561
-
(2007)
Genes Dev
, vol.21
, pp. 552-561
-
-
Nakayama, T.1
Nishioka, K.2
Dong, Y.X.3
Shimojima, T.4
Hirose, S.5
-
127
-
-
33947098453
-
Histone replacement marks the boundaries of cis-regulatory domains
-
1:CAS:528:DC%2BD2sXisVKrsrg%3D 17347439
-
Mito Y, Henikoff JG, Henikoff S (2007) Histone replacement marks the boundaries of cis-regulatory domains. Science 315:1408-1411
-
(2007)
Science
, vol.315
, pp. 1408-1411
-
-
Mito, Y.1
Henikoff, J.G.2
Henikoff, S.3
-
128
-
-
77952996319
-
Genome-wide kinetics of nucleosome turnover determined by metabolic labeling of histones
-
1:CAS:528:DC%2BC3cXmsVGjsb8%3D 2879085 20508129
-
Deal RB, Henikoff JG, Henikoff S (2010) Genome-wide kinetics of nucleosome turnover determined by metabolic labeling of histones. Science 328:1161-1164
-
(2010)
Science
, vol.328
, pp. 1161-1164
-
-
Deal, R.B.1
Henikoff, J.G.2
Henikoff, S.3
-
129
-
-
33847070442
-
The role of chromatin during transcription
-
1:CAS:528:DC%2BD2sXis12ju7c%3D 17320508
-
Li B, Carey M, Workman JL (2007) The role of chromatin during transcription. Cell 128:707-719
-
(2007)
Cell
, vol.128
, pp. 707-719
-
-
Li, B.1
Carey, M.2
Workman, J.L.3
-
130
-
-
0037184938
-
RNA polymerase i propagates unidirectional spreading of rDNA silent chromatin
-
1:CAS:528:DC%2BD3sXis1Kitw%3D%3D 12507427
-
Buck SW, Sandmeier JJ, Smith JS (2002) RNA polymerase I propagates unidirectional spreading of rDNA silent chromatin. Cell 111:1003-1014
-
(2002)
Cell
, vol.111
, pp. 1003-1014
-
-
Buck, S.W.1
Sandmeier, J.J.2
Smith, J.S.3
-
131
-
-
66349126902
-
Limiting the extent of the RDN1 heterochromatin domain by a silencing barrier and Sir2 protein levels in Saccharomyces cerevisiae
-
1:CAS:528:DC%2BD1MXlvFWjs7k%3D 2682026 19289503
-
Biswas M, Maqani N, Rai R, Kumaran SP, Iyer KR, Sendinc E, Smith JS, Laloraya S (2009) Limiting the extent of the RDN1 heterochromatin domain by a silencing barrier and Sir2 protein levels in Saccharomyces cerevisiae. Mol Cell Biol 29:2889-2898
-
(2009)
Mol Cell Biol
, vol.29
, pp. 2889-2898
-
-
Biswas, M.1
Maqani, N.2
Rai, R.3
Kumaran, S.P.4
Iyer, K.R.5
Sendinc, E.6
Smith, J.S.7
Laloraya, S.8
-
132
-
-
23044498502
-
Comprehensive analysis of heterochromatin- and RNAi-mediated epigenetic control of the fission yeast genome
-
1:CAS:528:DC%2BD2MXmsFKlsrs%3D 15976807
-
Cam HP, Sugiyama T, Chen ES, Chen X, FitzGerald PC, Grewal SI (2005) Comprehensive analysis of heterochromatin- and RNAi-mediated epigenetic control of the fission yeast genome. Nat Genet 37:809-819
-
(2005)
Nat Genet
, vol.37
, pp. 809-819
-
-
Cam, H.P.1
Sugiyama, T.2
Chen, E.S.3
Chen, X.4
Fitzgerald, P.C.5
Grewal, S.I.6
-
133
-
-
30944432294
-
A heterochromatin barrier partitions the fission yeast centromere into discrete chromatin domains
-
1:CAS:528:DC%2BD28Xosl2msg%3D%3D 16431364
-
Scott KC, Merrett SL, Willard HF (2006) A heterochromatin barrier partitions the fission yeast centromere into discrete chromatin domains. Curr Biol 16:119-129
-
(2006)
Curr Biol
, vol.16
, pp. 119-129
-
-
Scott, K.C.1
Merrett, S.L.2
Willard, H.F.3
-
134
-
-
80051751605
-
TRNA genes protect a reporter gene from epigenetic silencing in mouse cells
-
1:CAS:528:DC%2BC38XnvFKlsQ%3D%3D 3219543 21822054
-
Ebersole T, Kim JH, Samoshkin A, Kouprina N, Pavlicek A, White RJ, Larionov V (2011) tRNA genes protect a reporter gene from epigenetic silencing in mouse cells. Cell Cycle 10:2779-2791
-
(2011)
Cell Cycle
, vol.10
, pp. 2779-2791
-
-
Ebersole, T.1
Kim, J.H.2
Samoshkin, A.3
Kouprina, N.4
Pavlicek, A.5
White, R.J.6
Larionov, V.7
-
135
-
-
84857190176
-
Human tRNA genes function as chromatin insulators
-
1:CAS:528:DC%2BC3MXhsVOisL3N 3261562 22085927
-
Raab JR, Chiu J, Zhu J, Katzman S, Kurukuti S, Wade PA, Haussler D, Kamakaka RT (2012) Human tRNA genes function as chromatin insulators. EMBO J 31:330-350
-
(2012)
EMBO J
, vol.31
, pp. 330-350
-
-
Raab, J.R.1
Chiu, J.2
Zhu, J.3
Katzman, S.4
Kurukuti, S.5
Wade, P.A.6
Haussler, D.7
Kamakaka, R.T.8
-
136
-
-
33646912186
-
A role for TFIIIC transcription factor complex in genome organization
-
1:CAS:528:DC%2BD28Xls1ShsbY%3D 16751097
-
Noma K, Cam HP, Maraia RJ, Grewal SI (2006) A role for TFIIIC transcription factor complex in genome organization. Cell 125:859-872
-
(2006)
Cell
, vol.125
, pp. 859-872
-
-
Noma, K.1
Cam, H.P.2
Maraia, R.J.3
Grewal, S.I.4
-
137
-
-
57349129792
-
TFIIIC binding sites function as both heterochromatin barriers and chromatin insulators in Saccharomyces cerevisiae
-
1:CAS:528:DC%2BD1cXhsFWktbzK 2593192 18849469
-
Simms TA, Dugas SL, Gremillion JC, Ibos ME, Dandurand MN, Toliver TT, Edwards DJ, Donze D (2008) TFIIIC binding sites function as both heterochromatin barriers and chromatin insulators in Saccharomyces cerevisiae. Eukaryot Cell 7:2078-2086
-
(2008)
Eukaryot Cell
, vol.7
, pp. 2078-2086
-
-
Simms, T.A.1
Dugas, S.L.2
Gremillion, J.C.3
Ibos, M.E.4
Dandurand, M.N.5
Toliver, T.T.6
Edwards, D.J.7
Donze, D.8
-
138
-
-
34447515727
-
Developmentally regulated activation of a SINE B2 repeat as a domain boundary in organogenesis
-
1:CAS:528:DC%2BD2sXnsFaqtrc%3D 17626886
-
Lunyak VV, Prefontaine GG, Nunez E, Cramer T, Ju BG, Ohgi KA, Hutt K, Roy R, Garcia-Diaz A, Zhu X et al (2007) Developmentally regulated activation of a SINE B2 repeat as a domain boundary in organogenesis. Science 317:248-251
-
(2007)
Science
, vol.317
, pp. 248-251
-
-
Lunyak, V.V.1
Prefontaine, G.G.2
Nunez, E.3
Cramer, T.4
Ju, B.G.5
Ohgi, K.A.6
Hutt, K.7
Roy, R.8
Garcia-Diaz, A.9
Zhu, X.10
-
139
-
-
79952261267
-
Dioxin receptor and SLUG transcription factors regulate the insulator activity of B1 SINE retrotransposons via an RNA polymerase switch
-
1:CAS:528:DC%2BC3MXjt1aisbw%3D 3044856 21324874
-
Roman AC, Gonzalez-Rico FJ, Molto E, Hernando H, Neto A, Vicente-Garcia C, Ballestar E, Gomez-Skarmeta JL, Vavrova-Anderson J, White RJ et al (2011) Dioxin receptor and SLUG transcription factors regulate the insulator activity of B1 SINE retrotransposons via an RNA polymerase switch. Genome Res 21:422-432
-
(2011)
Genome Res
, vol.21
, pp. 422-432
-
-
Roman, A.C.1
Gonzalez-Rico, F.J.2
Molto, E.3
Hernando, H.4
Neto, A.5
Vicente-Garcia, C.6
Ballestar, E.7
Gomez-Skarmeta, J.L.8
Vavrova-Anderson, J.9
White, R.J.10
-
140
-
-
84864315587
-
HP1(Swi6) mediates the recognition and destruction of heterochromatic RNA transcripts
-
1:CAS:528:DC%2BC38XosVals7w%3D 22683269
-
Keller C, Adaixo R, Stunnenberg R, Woolcock KJ, Hiller S, Buhler M (2012) HP1(Swi6) mediates the recognition and destruction of heterochromatic RNA transcripts. Mol Cell 47:215-227
-
(2012)
Mol Cell
, vol.47
, pp. 215-227
-
-
Keller, C.1
Adaixo, R.2
Stunnenberg, R.3
Woolcock, K.J.4
Hiller, S.5
Buhler, M.6
-
141
-
-
84881474349
-
Noncoding RNAs prevent spreading of a repressive histone mark
-
1:CAS:528:DC%2BC3sXhtFCjtL%2FN 23872991
-
Keller C, Kulasegaran-Shylini R, Shimada Y, Hotz HR, Buhler M (2013) Noncoding RNAs prevent spreading of a repressive histone mark. Nat Struct Mol Biol 20:994-1000
-
(2013)
Nat Struct Mol Biol
, vol.20
, pp. 994-1000
-
-
Keller, C.1
Kulasegaran-Shylini, R.2
Shimada, Y.3
Hotz, H.R.4
Buhler, M.5
-
142
-
-
0029795638
-
Genetic and molecular analysis of the gypsy chromatin insulator of Drosophila
-
1:CAS:528:DyaK28XlsFeisr8%3D 38435 8790337
-
Gdula DA, Gerasimova TI, Corces VG (1996) Genetic and molecular analysis of the gypsy chromatin insulator of Drosophila. Proc Natl Acad Sci USA 93:9378-9383
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 9378-9383
-
-
Gdula, D.A.1
Gerasimova, T.I.2
Corces, V.G.3
-
143
-
-
0042978644
-
Visualization of chromatin domains created by the gypsy insulator of Drosophila
-
1:CAS:528:DC%2BD3sXms1Sqtro%3D 2173808 12925706
-
Byrd K, Corces VG (2003) Visualization of chromatin domains created by the gypsy insulator of Drosophila. J Cell Biol 162:565-574
-
(2003)
J Cell Biol
, vol.162
, pp. 565-574
-
-
Byrd, K.1
Corces, V.G.2
-
144
-
-
34249026300
-
High-resolution profiling of histone methylations in the human genome
-
1:CAS:528:DC%2BD2sXmtFKjsro%3D 17512414
-
Barski A, Cuddapah S, Cui K, Roh TY, Schones DE, Wang Z, Wei G, Chepelev I, Zhao K (2007) High-resolution profiling of histone methylations in the human genome. Cell 129:823-837
-
(2007)
Cell
, vol.129
, pp. 823-837
-
-
Barski, A.1
Cuddapah, S.2
Cui, K.3
Roh, T.Y.4
Schones, D.E.5
Wang, Z.6
Wei, G.7
Chepelev, I.8
Zhao, K.9
-
145
-
-
60149095014
-
Global analysis of the insulator binding protein CTCF in chromatin barrier regions reveals demarcation of active and repressive domains
-
1:CAS:528:DC%2BD1MXptFWjsQ%3D%3D 2612964 19056695
-
Cuddapah S, Jothi R, Schones DE, Roh TY, Cui K, Zhao K (2009) Global analysis of the insulator binding protein CTCF in chromatin barrier regions reveals demarcation of active and repressive domains. Genome Res 19:24-32
-
(2009)
Genome Res
, vol.19
, pp. 24-32
-
-
Cuddapah, S.1
Jothi, R.2
Schones, D.E.3
Roh, T.Y.4
Cui, K.5
Zhao, K.6
-
146
-
-
0842310349
-
CTCF tethers an insulator to subnuclear sites, suggesting shared insulator mechanisms across species
-
1:CAS:528:DC%2BD2cXhsFOhsrg%3D 14759373
-
Yusufzai TM, Tagami H, Nakatani Y, Felsenfeld G (2004) CTCF tethers an insulator to subnuclear sites, suggesting shared insulator mechanisms across species. Mol Cell 13:291-298
-
(2004)
Mol Cell
, vol.13
, pp. 291-298
-
-
Yusufzai, T.M.1
Tagami, H.2
Nakatani, Y.3
Felsenfeld, G.4
-
147
-
-
33746063711
-
CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2
-
1:CAS:528:DC%2BD28XntFWmsLo%3D 1484419 16815976
-
Kurukuti S, Tiwari VK, Tavoosidana G, Pugacheva E, Murrell A, Zhao Z, Lobanenkov V, Reik W, Ohlsson R (2006) CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2. Proc Natl Acad Sci USA 103:10684-10689
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 10684-10689
-
-
Kurukuti, S.1
Tiwari, V.K.2
Tavoosidana, G.3
Pugacheva, E.4
Murrell, A.5
Zhao, Z.6
Lobanenkov, V.7
Reik, W.8
Ohlsson, R.9
-
148
-
-
33748259774
-
CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus
-
1:CAS:528:DC%2BD28XptlSntrY%3D 1560409 16951251
-
Splinter E, Heath H, Kooren J, Palstra RJ, Klous P, Grosveld F, Galjart N, de Laat W (2006) CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus. Genes Dev 20:2349-2354
-
(2006)
Genes Dev
, vol.20
, pp. 2349-2354
-
-
Splinter, E.1
Heath, H.2
Kooren, J.3
Palstra, R.J.4
Klous, P.5
Grosveld, F.6
Galjart, N.7
De Laat, W.8
-
149
-
-
58149498240
-
CTCF-dependent enhancer-blocking by alternative chromatin loop formation
-
1:CAS:528:DC%2BD1MXhsFWktg%3D%3D 2629272 19074263
-
Hou C, Zhao H, Tanimoto K, Dean A (2008) CTCF-dependent enhancer-blocking by alternative chromatin loop formation. Proc Natl Acad Sci USA 105:20398-20403
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 20398-20403
-
-
Hou, C.1
Zhao, H.2
Tanimoto, K.3
Dean, A.4
-
150
-
-
42249105007
-
The insulator factor CTCF controls MHC class II gene expression and is required for the formation of long-distance chromatin interactions
-
1:CAS:528:DC%2BD1cXkvVyrsr0%3D 2292219 18347100
-
Majumder P, Gomez JA, Chadwick BP, Boss JM (2008) The insulator factor CTCF controls MHC class II gene expression and is required for the formation of long-distance chromatin interactions. J Exp Med 205:785-798
-
(2008)
J Exp Med
, vol.205
, pp. 785-798
-
-
Majumder, P.1
Gomez, J.A.2
Chadwick, B.P.3
Boss, J.M.4
-
151
-
-
33750203582
-
Circular chromosome conformation capture (4C) uncovers extensive networks of epigenetically regulated intra- and interchromosomal interactions
-
1:CAS:528:DC%2BD28XhtFeisbvP 17033624
-
Zhao Z, Tavoosidana G, Sjolinder M, Gondor A, Mariano P, Wang S, Kanduri C, Lezcano M, Sandhu KS, Singh U et al (2006) Circular chromosome conformation capture (4C) uncovers extensive networks of epigenetically regulated intra- and interchromosomal interactions. Nat Genet 38:1341-1347
-
(2006)
Nat Genet
, vol.38
, pp. 1341-1347
-
-
Zhao, Z.1
Tavoosidana, G.2
Sjolinder, M.3
Gondor, A.4
Mariano, P.5
Wang, S.6
Kanduri, C.7
Lezcano, M.8
Sandhu, K.S.9
Singh, U.10
-
152
-
-
33645814398
-
CTCF mediates interchromosomal colocalization between Igf2/H19 and Wsb1/Nf1
-
1:CAS:528:DC%2BD28XjtlOjsrs%3D 16614224
-
Ling JQ, Li T, Hu JF, Vu TH, Chen HL, Qiu XW, Cherry AM, Hoffman AR (2006) CTCF mediates interchromosomal colocalization between Igf2/H19 and Wsb1/Nf1. Science 312:269-272
-
(2006)
Science
, vol.312
, pp. 269-272
-
-
Ling, J.Q.1
Li, T.2
Hu, J.F.3
Vu, T.H.4
Chen, H.L.5
Qiu, X.W.6
Cherry, A.M.7
Hoffman, A.R.8
-
153
-
-
35649000946
-
Evidence that homologous X-chromosome pairing requires transcription and Ctcf protein
-
1:CAS:528:DC%2BD2sXht1aqurnJ 17952071
-
Xu N, Donohoe ME, Silva SS, Lee JT (2007) Evidence that homologous X-chromosome pairing requires transcription and Ctcf protein. Nat Genet 39:1390-1396
-
(2007)
Nat Genet
, vol.39
, pp. 1390-1396
-
-
Xu, N.1
Donohoe, M.E.2
Silva, S.S.3
Lee, J.T.4
-
154
-
-
39149121436
-
Cohesin mediates transcriptional insulation by CCCTC-binding factor
-
1:CAS:528:DC%2BD1cXhvVymsL4%3D 18235444
-
Wendt KS, Yoshida K, Itoh T, Bando M, Koch B, Schirghuber E, Tsutsumi S, Nagae G, Ishihara K, Mishiro T et al (2008) Cohesin mediates transcriptional insulation by CCCTC-binding factor. Nature 451:796-801
-
(2008)
Nature
, vol.451
, pp. 796-801
-
-
Wendt, K.S.1
Yoshida, K.2
Itoh, T.3
Bando, M.4
Koch, B.5
Schirghuber, E.6
Tsutsumi, S.7
Nagae, G.8
Ishihara, K.9
Mishiro, T.10
-
155
-
-
46149113242
-
CTCF physically links cohesin to chromatin
-
1:CAS:528:DC%2BD1cXnvVyrsro%3D 2448833 18550811
-
Rubio ED, Reiss DJ, Welcsh PL, Disteche CM, Filippova GN, Baliga NS, Aebersold R, Ranish JA, Krumm A (2008) CTCF physically links cohesin to chromatin. Proc Natl Acad Sci USA 105:8309-8314
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 8309-8314
-
-
Rubio, E.D.1
Reiss, D.J.2
Welcsh, P.L.3
Disteche, C.M.4
Filippova, G.N.5
Baliga, N.S.6
Aebersold, R.7
Ranish, J.A.8
Krumm, A.9
-
156
-
-
0037205232
-
Chromatin boundaries in budding yeast: The nuclear pore connection
-
1:CAS:528:DC%2BD38XksVGgsrg%3D 12062099
-
Ishii K, Arib G, Lin C, Van Houwe G, Laemmli UK (2002) Chromatin boundaries in budding yeast: the nuclear pore connection. Cell 109:551-562
-
(2002)
Cell
, vol.109
, pp. 551-562
-
-
Ishii, K.1
Arib, G.2
Lin, C.3
Van Houwe, G.4
Laemmli, U.K.5
-
157
-
-
0033522443
-
Cohabitation of insulators and silencing elements in yeast subtelomeric regions
-
1:CAS:528:DyaK1MXjtlKhsLw%3D 1171334 10228166
-
Fourel G, Revardel E, Koering CE, Gilson E (1999) Cohabitation of insulators and silencing elements in yeast subtelomeric regions. EMBO J 18:2522-2537
-
(1999)
EMBO J
, vol.18
, pp. 2522-2537
-
-
Fourel, G.1
Revardel, E.2
Koering, C.E.3
Gilson, E.4
-
158
-
-
0033522444
-
Limitations of silencing at native yeast telomeres
-
1:CAS:528:DyaK1MXjtlKhsL0%3D 1171335 10228167
-
Pryde FE, Louis EJ (1999) Limitations of silencing at native yeast telomeres. EMBO J 18:2538-2550
-
(1999)
EMBO J
, vol.18
, pp. 2538-2550
-
-
Pryde, F.E.1
Louis, E.J.2
|