Intron-mediated enhancement of gene expression independent of unique intron sequences and splicing

Plant Physiology

Volumn 122, Issue 2, 2000, Pages 535-542

  Rose, Alan B ^a   Beliakoff, Jason A ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF ARIZONA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARABIDOPSIS; BETA GLUCURONIDASE; GENE DELETION; GENE FUSION; GENE SEQUENCING; GENETIC TRANSCRIPTION; INTRON; MESSENGER RNA; POINT MUTATION; RNA SPLICING;

ARABIDOPSIS; EMBRYOPHYTA;

EID: 0034143589     PISSN: 00320889     EISSN: None     Source Type: Journal    
DOI: 10.1104/pp.122.2.535     Document Type: Article

References (46)

1. Aebi M, Hornig H, Padgett RA, Reiser J, Weissmann C (1986) Sequence requirements for splicing of higher eukaryotic nuclear pre-mRNA. Cell 47: 555-565
2. Bechtold N, Ellis J, Pelletier G (1993) In planta Agrobacterium mediated gene transfer by infiltration of adult Arabidopsis thaliana plants. CR Acad Sci Ser III Sci Vie 316: 1194-1199
3. Bentley D (1999) Coupling RNA polymerase II transcription with pre-mRNA processing. Curr Opin Cell Biol 11: 347-351
4. Brown JWS (1996) Arabidopsis intron mutations and pre-mRNA splicing. Plant J 10: 771-780
5. Brown JWS, Smith P, Simpson CG (1996) Arabidopsis consensus intron sequences. Plant Mol Biol 32: 531-535
6. Buchman AR, Berg P (1988) Comparison of intron-dependent and intron-independent gene expression. Mol Cell Biol 8: 4395-4405
7. Callis J, Fromm M, Walbot V (1987) Introns increase gene expression in cultured maize cells. Genes Dev 1: 1183-1200
8. Chee PP, Klassy RC, Slightom JL (1986) Expression of a bean storage protein 'phaseolin minigene' in foreign plant tissues. Gene 41: 47-57
9. Chung S, Perry R (1989) Importance of introns for expression of mouse ribosomal protein gene rpL32. Mol Cell Biol 9: 2075-2082
10. Clancy M, Vasil V, Hannah LC, Vasil IK (1994) Maize Shrunken-1 intron and exon regions increase gene expression in maize protoplasts. Plant Sci 98: 151-161
11. Curie C, Axelos M, Bardet C, Atanassova R, Chaubet N, Lescure B (1993) Modular organization and developmental activity of an Arabidopsis thaliana EF-1α gene promoter. Mol Gen Genet 238: 428-436
12. Dean C, Favreau M, Bond-Nutter D, Bedbrook J, Dunsmuir P (1989) Sequences downstream of translation start regulate quantitative expression of two petunia rbcS genes. Plant Cell 1: 201-208
13. Dennis ES, Gerlach WL, Pryor AJ, Bennetzen JL, Inglis A, Llewellyn D, Sachs MM, Ferl RJ, Peacock WJ (1984) Molecular analysis of the alcohol dehydrogenase (Adh1) gene of maize. Nucleic Acids Res 12: 3983-4000
14. Donath M, Mendel R, Cerff R, Martin W (1995) Intron-dependent transient expression of the maize GapA1 gene. Plant Mol Biol 28: 667-676
15. Gidekel M, Jimenez B, Herrera-Estrella L (1996) The first intron of the Arabidopsis thaliana gene coding for elongation factor 1β contains an enhancer-like element. Gene 170: 201-206
16. Gniadkowski M, Hemmings-Mieszczak M, Klahre U, Liu H-X, Filipowicz W (1996) Characterisation of intronic uridine-rich sequence elements acting as possible targets for nuclear proteins during pre-mRNA splicing in Nicotiana plumbaginifolia. Nucleic Acids Res 24: 619-627
17. Goodall GJ, Filipowicz W (1990) The minimum functional length of pre-mRNA introns in monocots and dicots. Plant Mol Biol 14: 727-733
18. Huang MTF, Gorman CM (1990) Intervening sequences increase efficiency of RNA 3′ processing and accumulation of cytoplasmic RNA. Nucleic Acids Res 18: 937-947
19. Izaurralde E, Lewis J, Gamberi C, Jarmolowski A, McGuigan C, Mattaj IW (1995) A cap-binding protein complex mediating U snRNA export. Nature 376: 709-712
20. Izaurralde E, Lewis J, McGuigan C, Jankowska M, Darzynkiewicz E, Mattaj IW (1994) A nuclear cap binding protein complex involved in pre-mRNA splicing. Cell 78: 657-668
21. Klee HJ, Yanofsky MF, Nester EW (1985) Vectors for transformation of higher plants. Biotechnology 3: 637-642
22. Koncz C, Schell J (1986) The promoter of TL-DNA gene 5 controls the tissue-specific expression of chimaeric genes carried by a novel type of Agrobacterium binary vector. Mol Gen Genet 204: 383-396
23. Koziel MG, Carozzi NB, Desai N (1996) Optimizing expression of transgenes with an emphasis on post-transcriptional events. Plant Mol Biol 32: 393-405
24. Krecic AM, Swanson MS (1999) hnRNP complexes: composition, structure, and function. Curr Opin Cell Biol 11: 363-371
25. Leon P, Planckaert F, Walbot V (1991) Transient gene expression in protoplasts of Phaseolus vulgaris isolated from a cell suspension culture. Plant Physiol 95: 968-972
26. Liu H-X, Filipowicz W (1996) Mapping of branchpoint nucleotides in mutant pre-mRNAs expressed in plant cells. Plant J 9: 381-389
27. Lou H, Gagel RF, Berget SM (1996) An intron enhancer recognized by splicing factors activates polyadenylation. Genes Dev 10: 208-219
28. Luehrsen KR, Walbot V (1991) Intron enhancement of gene expression and the splicing efficiency of introns in maize cells. Mol Gen Genet 225: 81-93
29. Luehrsen KR, Walbot V (1994) Addition of A-and U-rich sequence increases the splicing efficiency of a deleted form of a maize intron. Plant Mol Biol 24: 449-463
30. Maas C, Laufs J, Grant S, Korfhage C, Werr W (1991) The combination of a novel stimulatory element in the first exon of the maize Shrunken-1 gene with the following intron 1 enhances reporter gene expression up to 1000-fold. Plant Mol Biol 16: 199-207
31. Mascarenhas D, Mettler IJ, Pierce DA, Lowe HW (1990) Intronmediated enhancement of heterologous gene expression in maize. Plant Mol Biol 15: 913-920
32. McElroy D, Zhang W, Cao J, Wu R (1990) Isolation of an efficient actin promoter for use in rice transformation. Plant Cell 2: 163-171
33. Meredith J, Storti RV (1993) Developmental regulation of the Drosophila tropomyosin II gene in different muscles is controlled by muscle-type-specific intron enhancer elements and distal and proximal promoter control elements. Dev Biol 159: 500-512
34. Minvielle-Sebastia L, Keller W (1999) mRNA polyadenylation and its coupling to other RNA processing reactions and to transcription. Curr Opin Cell Biol 11: 352-357
35. Newman AJ, Lin R-J, Cheng S-C, Abelson J (1985) Molecular consequences of specific intron mutations on yeast mRNA splicing in vivo and in vitro. Cell 42: 335-344
36. Niwa M, Rose SD, Berget SM (1990) In vitro polyadenylation is stimulated by the presence of an upstream intron. Genes Dev 4: 1552-1559
37. Norris SR, Meyer SE, Callis J (1993) The intron of Arabidopsis thaliana polyubiquitin genes is conserved in location and is a quantitative determinant of chimeric gene expression. Plant Mol Biol 21: 895-906
38. Okkema PG, Harrison SW, Plunger V, Aryana A, Fire A (1993) Sequence requirements for myosin gene expression and regulation in Caenorhabditis elegans. Genetics 135: 385-404
39. Radwanski ER, Zhao J, Last RL (1995) Arabidopsis thaliana tryptophan synthase alpha: gene cloning, expression, and subunit interaction. Mol Gen Genet 248: 657-667
40. Rethmeier N, Seurinck J, Van Montagu M, Cornelissen M (1997) Intron-mediated enhancement of transgene expression in maize is a nuclear, gene-dependent process. Plant J 12: 895-899
41. Rose AB, Last RL (1997) Introns act post-transcriptionally to increase expression of the Arabidopsis thaliana tryptophan pathway gene PAT1. Plant J 11: 455-464
42. Simpson GG, Filipowicz W (1996) Splicing of precursors to mRNA in higher plants: mechanism, regulation and sub-nuclear organisation of the spliceosomal machinery. Plant Mol Biol 32: 1-41
43. Sinibaldi RM, Mettler IJ (1992) Intron splicing and intron-mediated enhanced expression in monocots. In WE Cohn, K Moldave, eds, Progress in Nucleic Acid Research and Molecular Biology, Vol 42. Academic Press, New York, pp 229-257
44. Sullivan ML, Green PJ (1993) Post-transcriptional regulation of nuclear-encoded genes in higher plants: the roles of mRNA stability and translation. Plant Mol Biol 23: 1091-1104
45. Xu Y, Yu H, Hall TC (1994) Rice triosephosphate isomerase gene 5′ sequence directs β-glucuronidase activity in transgenic tobacco but requires an intron for expression in rice. Plant Physiol 106: 459-467
46. Zhang S-H, Lawton MA, Hunter T, Lamb CJ (1994) atpk1, a novel ribosomal protein kinase gene from Arabidopsis: I. Isolation, characterization, and expression. J Biol Chem 269: 17586-17592