Manufacturing of solid dispersions of poorly water soluble drugs by spray drying: Formulation and process considerations

International Journal of Pharmaceutics

Volumn 453, Issue 1, 2013, Pages 253-284

  Paudel, Amrit ^a   Worku, Zelalem Ayenew ^a   Meeus, Joke ^a   Guns, Sandra ^a   Van Den Mooter, Guy ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Amorphous; Formulation; Poorly soluble drugs; Process parameters; Solid dispersions; Spray drying

Indexed keywords

CARBOHYDRATE; CARVEDILOL; CEFUROXIME AXETIL; CELECOXIB; CELLULOSE DERIVATIVE; CLOPIDOGREL; COLLAGEN; CURCUMIN; CYCLOSPORIN A; FLURBIPROFEN; IBIPINABANT; IBUPROFEN; ITRACONAZOLE; MACROGOL; NITRENDIPINE; PEPTIDE; POLY(METHYL METHACRYLATE); POLYMER; REBAMIPIDE; SIBUTRAMINE; SIMVASTATIN; SOLVENT; TACROLIMUS; TENOXICAM; TOLBUTAMIDE; VALSARTAN; VINYL DERIVATIVE;

COMBUSTION; CONCENTRATION (PARAMETERS); CRYSTALLIZATION; DISPERSION; DOWNSTREAM PROCESSING; DRUG FORMULATION; DRUG RELEASE; DRUG STABILITY; ELECTROSPRAY; EMULSION; EVAPORATION; FLOW RATE; GAS FLOW; NEBULIZATION; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; REVIEW; SOLID DISPERSION; SPRAY DRYING; TEMPERATURE;

EID: 84877921505     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.07.015     Document Type: Review

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