Improvement of the dissolution rate of nitrendipine using a new pulse combustion drying method

Chemical and Pharmaceutical Bulletin

Volumn 55, Issue 8, 2007, Pages 1119-1125

  Wang, Liang ^a   Cui, Fu De ^a   Sunada, Hisakazu ^b  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b MEIJO UNIVERSITY   (Japan)

Author keywords

Dissolution; Poorly water soluble drug; Pulse combustion dryer system; Silica particle; Solid dispersion; Spray dryer

Indexed keywords

AEROSIL; NITRENDIPINE; POLYMER; POLYSORBATE 80;

ARTICLE; COMBUSTION; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DISSOLUTION; DRUG FORMULATION; DRUG SOLUBILITY; DRUG SYNTHESIS; HYDROGEN BOND; HYDROPHILICITY; INFRARED SPECTROSCOPY; PARTICLE SIZE; PHYSICAL CHEMISTRY; SHOCK WAVE; SOLUBILIZATION; SPRAY DRYING; X RAY DIFFRACTION;

ALGORITHMS; CALCIUM CHANNEL BLOCKERS; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHYSICAL; CRYSTALLOGRAPHY, X-RAY; DESICCATION; DRUG STABILITY; KINETICS; MICROSCOPY, ELECTRON, SCANNING; NITRENDIPINE; PARTICLE SIZE; POLYSORBATES; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SURFACE TENSION;

EID: 34548306554     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.55.1119     Document Type: Article

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