Effect of polymer hygroscopicity on the phase behavior of amorphous solid dispersions in the presence of moisture

Molecular Pharmaceutics

Volumn 7, Issue 2, 2010, Pages 477-490

  Rumondor, Alfred C F ^a,b   Taylor, Lynne S ^a  

^a PURDUE UNIVERSITY   (United States)

^b ASTRAZENECA   (United Kingdom)

Author keywords

Amorphous solid dispersion; Differential scanning calorimetry; Infrared spectroscopy; Miscibility; Moisture

Indexed keywords

FELODIPINE; HYPROMELLOSE ACETATE SUCCINATE; INDOMETACIN; PIMOZIDE; POLY(VINYLPYRROLIDONE CO VINYL ACETATE); POVIDONE; QUINIDINE; SUCCINIC ACID; UNCLASSIFIED DRUG;

ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DRUG STRUCTURE; HUMIDITY; INFRARED SPECTROSCOPY; MISCIBILITY; MOISTURE; PHASE SEPARATION; PRIORITY JOURNAL; SOLID; WETTABILITY;

CALORIMETRY, DIFFERENTIAL SCANNING; FELODIPINE; HUMIDITY; INDOMETHACIN; METHYLCELLULOSE; MODELS, THEORETICAL; MOLECULAR STRUCTURE; PIMOZIDE; POLYMERS; POLYVINYLS; POVIDONE; PYRROLIDINES; QUINIDINE; SPECTROPHOTOMETRY, INFRARED; WETTABILITY;

EID: 77950549481     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp9002283     Document Type: Article

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