Surface-enhanced crystallization of amorphous nifedipine

Molecular Pharmaceutics

Volumn 5, Issue 6, 2008, Pages 921-926

  Zhu, Lei ^a   Wong, Letitia ^a   Yu, Lian ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Amorphous solid; Coating; Glass transition; Nifedipine; Surface enhanced crystal growth

Indexed keywords

NIFEDIPINE;

ARTICLE; CRYSTALLIZATION; DRUG COATING; DRUG FORMULATION; DRUG STABILITY; DRUG STRUCTURE; ENTHALPY; GLASS TRANSITION TEMPERATURE; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; STRUCTURE ANALYSIS; SURFACE PROPERTY;

CRYSTALLIZATION; GLASS; GOLD; MOLECULAR STRUCTURE; NANOTECHNOLOGY; NIFEDIPINE; PARTICLE SIZE; SURFACE PROPERTIES; TIME FACTORS; TRANSITION TEMPERATURE; VASODILATOR AGENTS;

EID: 64649105863     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp8000638     Document Type: Article

References (17)

1. Yu, L. Amorphous pharmaceutical solids: preparation, characteriza-tion and stabilization. Adv. Drug Delivery Rev. 2001, 48, 27-42.
2. Zanotto, E. D. Experimental studies of surface nucleation and crystallization of glasses. In Ceramic Transactions: Nucleation and crystallization in liquids and glasses; Weinberg, M. C., Ed.; The American Ceramic Society: Westerville, OH, 1993; Vol. 30, pp 65-74.
3. Wu, T.; Yu, L. Surface Crystallization of Indomethacin Below Tg. Pharm. Res. 2006, 23, 2350-2355.
4. Aso, Y.; Yoshioka, S.; Kojima, S. Explanation of the crystalliza-tion rate of amorphous nifedipine and phenobarbital from their molecular mobility as measured by C-13 nuclear magnetic resonance relaxation time and the relaxation time obtained from the heating rate dependence of the glass transition temperature. J. Pharm. Sci. 2001, 90, 798-806.
5. Aso, Y.; Yoshioka, S.; Kojima, S. Molecular mobility-based estimation of the crystallization rates of amorphous nifedipine and phenobarbital in poly(vinylpyrrolidone) solid dispersions. J. Pharm. Sci. 2004, 93, 384-391.
6. Aso, Y.; Yoshioka, S.; Kojima, S. Relationship between the crystallization rates of amorphous nifedipine, phenobarbital, and flopropione, and their molecular mobility as measured by their enthalpy relaxation and H-1 NMR relaxation times. J. Pharm. Sci. 2000, 89, 408-416.
7. Ishida, H.; Wu, T.; Yu, L. Sudden Rise of Crystal Growth Rate of Nifedipine near Tg without and with Polyvinylpyrrolidone. J. Pharm. Sci. 2007, 96, 1131-1138.
8. Weber, R.; Grotkopp, I.; Stettner, J.; Tolan, M.; Press, W. Embedding of Gold Nanoclusters on Polystyrene Surfaces: Influence of the Surface Modification on the Glass Transition. Macromolecules 2003, 36, 9100-9106.
9. Bell, R. C.; Wang, H.; Iedema, M. J.; Cowin, J. P. Nanometer- Resolved Interfacial Fluidity. J. Am. Chem. Soc. 2003, 125, 5176-5185.
10. Swallen, S.; Kearns, K.; Mapes, M.; McMahon, R.; Kim, S.; Ediger, M.; Yu, L.; Wu, T.; Satija, S. Organic Glasses with Exceptional Thermodynamic and Kinetic Stability. Science 2007, 315, 353-356.
11. Diaz-Mora, N.; Zanotto, E. D.; Hergt, R.; Muller, R. Surface crystallization and texture in cordierite glasses. J. Non-Cryst. Solids 2000, 273, 81-93.
12. Fakhraai, Z.; Forrest, J. A. Measuring the surface dynamics of glassy polymers. Science 2008, 319, 600-604.
13. Bhugra, C.; Shmeis, R.; Krill, S. L.; Pikal, M. J. Predictions of Onset of Crystallization from Experimental Relaxation Times I-Correlation of Molecular Mobility from Temperatures Above the Glass Transition to Temperatures below the Glass Transition. Pharm. Res. 2006, 23, 2277-2290.
14. Hatase, M.; Hanaya, M.; Oguni, M. Studies of homogeneous-nucleation-based crystal growth: significant role of phenyl ring in the structure formation. J. Non-Cryst. Solids 2004, 333, 129-136.
15. Sun, Y.; Xi, H.; Ediger, M. D.; Yu, L. Diffusionless Crystal Growth from Glass Has Precursor in Equilibrium Liquid. J. Phys. Chem.. B 2008, 112 (3), 661-664.
16. Sun, Y.; Xi, H.; Ediger, M. D.; Yu, L. Crystallization near Glass Transition: Transition from Diffusion-Controlled to Diffusionless Crystal Growth Studied with Seven Polymorphs. J. Phys. Chem. B 2008, 112, 5594-5601.
17. Ediger, M. D.; Harrowell, P.; Yu, L. Crystal growth kinetics exhibit a fragility-dependent decoupling from viscosity. J. Chem. Phys. 2008, 128 (3), 034709/1-034709/6.