Study of the physicochemical properties and stability of solid dispersions of loperamide and PEG6000 prepared by spray drying

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 59, Issue 1, 2005, Pages 119-126

  Weuts, Ilse ^a   Kempen, Dieter ^a   Verreck, Geert ^b   Decorte, Annelies ^b   Heymans, Koen ^b   Peeters, Jef ^b   Brewster, Marcus ^b   Mooter, Guy Van Den ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

Author keywords

Differential scanning calorimetry; Dissolution properties; Loperamide; PEG6000; Physicochemical properties; Solid dispersions; Stability

Indexed keywords

LOPERAMIDE; MACROGOL 6000;

ARTICLE; CRYSTAL; DISPERSION; DRUG SOLUBILITY; DRUG STABILITY; DRUG STORAGE; HUMIDITY; PHYSICAL CHEMISTRY; SPRAY DRYING; STORAGE TEMPERATURE;

CHEMISTRY, PHYSICAL; CRYSTALLIZATION; DRUG STABILITY; LOPERAMIDE; POLYETHYLENE GLYCOLS;

EID: 9644284353     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2004.05.011     Document Type: Article

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