Characterization and stability of ternary solid dispersions with PVP and PHPMA

International Journal of Pharmaceutics

Volumn 419, Issue 1-2, 2011, Pages 20-27

  Al Obaidi, Hisham ^a   Ke, Peng ^b   Brocchini, Steve ^b   Buckton, Graham ^b  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Amorphous solid dispersion; Flory Huggins; Free energy of mixing; Hydrogen bonding; Solubility; Spray drying

Indexed keywords

ACTIVE PHARMACEUTICAL INGREDIENT; CHEMICAL AGENT; GRISEOFULVIN; METHACRYLIC ACID DERIVATIVE; PHENINDIONE; POLY(2 HYDROXYPROPYL METHACRYLATE); POVIDONE; PROGESTERONE; UNCLASSIFIED DRUG;

ARTICLE; DISPERSION; DRUG MIXTURE; HYDROGEN BOND; MELTING POINT; PRIORITY JOURNAL; SPRAY DRYING; TERNARY SOLID DISPERSION;

CRYSTALLIZATION; DRUG CARRIERS; DRUG STABILITY; GRISEOFULVIN; HYDROGEN BONDING; PHENINDIONE; POLYMETHACRYLIC ACIDS; POVIDONE; PROGESTERONE; SOLUBILITY; TRANSITION TEMPERATURE;

EID: 80053566493     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.06.052     Document Type: Article

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