Influence of various drugs on the glass transition temperature of poly(vinylpyrrolidone): A thermodynamic and spectroscopic investigation

International Journal of Pharmaceutics

Volumn 225, Issue 1-2, 2001, Pages 83-96

  Nair, R ^a   Nyamweya, N ^a   Gonen S ^b   Martinez Miranda L J ^c   Hoag, S W ^a  

^a UNIVERSITY OF MARYLAND   (United States)

^b Bldg 142   (United States)

^c UNIVERSITY OF MARYLAND   (United States)

Author keywords

Drug polymer interactions; Glass transition; Poly(vinylpyrrolidone); Solubility parameter; Spectroscopy

Indexed keywords

DIETHYLCARBAMAZINE; GRISEOFULVIN; NAPROXEN; PARACETAMOL; POLYMER; POVIDONE; PROPRANOLOL; SALICYLAMIDE;

ARTICLE; DATA ANALYSIS; DIFFERENTIAL SCANNING CALORIMETRY; DRUG SOLUBILITY; HYDROGEN BOND; INFRARED SPECTROSCOPY; MISCIBILITY; PRIORITY JOURNAL; SPECTROSCOPY; TEMPERATURE; THERMODYNAMICS; X RAY DIFFRACTION;

CHEMISTRY, PHARMACEUTICAL; DRUG INTERACTIONS; GLASS; POVIDONE; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; THERMODYNAMICS; X-RAY DIFFRACTION;

EID: 0035964472     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(01)00767-0     Document Type: Article

References (34)

1. Migration of active ingredient between film coats and tablet cores
2. Fourier transform infrared spectroscopy: Probing the structure of multicomponent polymer blends
3. A practical guide to polymer miscibility
4. The solubilization of drug and excipient into hydroxypropyl methylcellulose (HPMC)-based film coating as a function of the coating parameters in a 24″ accela-cota
5. Estimation of miscibility of polymer blends using the solubility parameter concept
6. Acetaminophen
7. Ideal copolymers and the second order transition of synthetic rubbers 1. Non-crystalline co-polymers
8. Solubility parameters as predictors of miscibility in solid dispersions
9. Influence of water soluble and insoluble plasticizers on the physical and mechanical properties of acrylic resin copolymers
10. The use of solubility parameters in pharmaceutical dosage form design
11. Physicochemical characterization and drug release studies of naproxen solid dispersions using lactose as a carrier
12. Solubility studies on ethylcellulose used in film coating
13. Thermal analysis of glassy pharmaceuticals
14. The effect of plasticizers on compatibility, mechanical properties, and adhesion strength of drug free Eudragit E films
15. Concerning the miscibility of poly(vinylphenol) blends-FTi.r. study
16. Assessment of polymer-polymer interactions in blends of HPMC and film forming polymers by modulated temperature differential scanning calorimetry
17. Thermal characterization of drug/polymer and excipient/polymer interactions in some films coating formulation
18. Effect of hydrogen bonding on the enthalpy of mixing and the composition dependence of the glass transition temperature of polymer blends
19. The cracking of film coatings on film-coated tablets-a theoretical approach with practical implications
20. The prediction of compatibility/incompatibility in blends of ethyl cellulose with hydroxypropyl methylcellulose or hydroxylpropyl cellulose using 2-dimensional solubility parameters maps
21. Interactions in colored powders and tablet formulations: A theoretial approach based on solubility parameters
22. Inhibitory effect of polyvinylpyrrolidone on the crystallization of drugs
23. Solid-state interaction of ibuprofen with polyvinylpyrrolidone
24. On a general relation involving the glass temperatures and coefficients of expansion of polymers
25. The influence of drug solubility on the quality of film-coated tablets
26. The effect of intermolecular forces on the glass transition of solute-polymer blends
27. Spectroscopic characterization of interactions between PVP and indomethacin in amorphous molecular disperisons
28. Griseofulvin
29. Non-traditional plasticization of polymeric films
30. Inhibition of indomethacin crystallization in poly(vinylpyrrolidone) coprecipitates