Improving drug solubility for oral delivery using solid dispersions

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 50, Issue 1, 2000, Pages 47-60

  Leuner, Christian ^a   Dressman, Jennifer ^a  

^a GOETHE UNIVERSITY   (Germany)

Author keywords

Amorphous state; Bioavailability; Dissolution; Eutectic mixture; Solid dispersion; Solid solution; Solubility

Indexed keywords

CARBAMAZEPINE; CARBOXYLIC ACID; CELLULOSE DERIVATIVE; DRUG; EMULSIFYING AGENT; FUROSEMIDE; GRISEOFULVIN; HYDROXYPROPYLMETHYLCELLULOSE; HYDROXYPROPYLMETHYLCELLULOSE PHTHALATE; INDOMETACIN; MACROGOL; MANNITOL; NAPROXEN; NICOTINAMIDE; NIFEDIPINE; NITROFURANTOIN; OFLOXACIN; OXAZEPAM; PARACETAMOL; PHENYTOIN; PIROXICAM; POLYMER; POLYOL; POLYVINYL ACETATE; POLYVINYL ALCOHOL; POVIDONE; POVIDONE DERIVATIVE; SUGAR; SULFATHIAZOLE; UREA;

DISPERSION; DISSOLUTION; DRUG BIOAVAILABILITY; DRUG FORMULATION; DRUG MANUFACTURE; DRUG SOLUBILITY; ORAL DRUG ADMINISTRATION; REVIEW; SOLUTION AND SOLUBILITY;

BIOLOGICAL AVAILABILITY; CHEMISTRY, PHARMACEUTICAL; DRUG DELIVERY SYSTEMS; EXCIPIENTS; SOLUBILITY; TERMINOLOGY;

EID: 0034601240     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0939-6411(00)00076-X     Document Type: Review

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