Study on mechanism for amorphous drug stabilization using Gelucire 50/13

Chemical and Pharmaceutical Bulletin

Volumn 57, Issue 9, 2009, Pages 937-942

  Shimpi, Shamkant Laxman ^a   Mahadik, Kakasaheb Ramoo ^b   Paradkar, Anant Raghunath ^c  

^a Aurobindo Pharma Ltd   (India)

^b BHARATI VIDYAPEETH DEEMED UNIVERSITY   (India)

^c UNIVERSITY OF BRADFORD   (United Kingdom)

Author keywords

Amorphous state; Gelucire; Mechanism; Molecular modeling; Solid dispersion; Stabilization

Indexed keywords

CELECOXIB; ETORICOXIB; GELUCIRE; POVIDONE IODINE;

ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DIFFUSE REFLECTANCE SPECTROSCOPY; DISPERSION; DRUG SOLUBILITY; DRUG STABILITY; DRUG STRUCTURE; HYDROGEN BOND; MOLECULAR INTERACTION; MOLECULAR MODEL; SOLID DISPERSION; SPRAY DRYING; STEREOCHEMISTRY; THERMOGRAVIMETRY; X RAY POWDER DIFFRACTION;

CALORIMETRY, DIFFERENTIAL SCANNING; CYCLOOXYGENASE INHIBITORS; DRUG COMPOUNDING; DRUG STABILITY; EXCIPIENTS; FATS; HYDROGEN BONDING; OILS; POVIDONE; PYRAZOLES; PYRIDINES; SPECTROPHOTOMETRY, INFRARED; SULFONAMIDES; SULFONES; X-RAY DIFFRACTION;

EID: 70349170163     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.57.937     Document Type: Article

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