The apparent plasticizing effect of polyethylene glycol (PEG) on the crystallinity of spray dried lactose/PEG composites

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 64, Issue 2, 2006, Pages 206-211

  Mosén, Kristina ^a,b   Bäckström, Kjell ^c   Thalberg, Kyrre ^c   Schaefer, Torben ^a   Axelsson, Anders ^b   Kristensen, Henning G ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b LUND UNIVERSITY   (Sweden)

^c ASTRAZENECA R AND D   (Sweden)

Author keywords

Crystallinity; Glass transition temperature; Lactose; Polyethylene glycol; Spray drying

Indexed keywords

LACTOSE; MACROGOL; MACROGOL 200; MACROGOL 4000; MACROGOL 8000; PLASTICIZER;

AQUEOUS SOLUTION; ARTICLE; COMPOSITE MATERIAL; CONCENTRATION (PARAMETERS); CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; GLASS TRANSITION TEMPERATURE; MOLECULAR WEIGHT; SPRAY DRYING; X RAY POWDER DIFFRACTION;

CALORIMETRY, DIFFERENTIAL SCANNING; COMPOSITE RESINS; CRYSTALLIZATION; DESICCATION; HUMIDITY; LACTOSE; MOLECULAR WEIGHT; PLASTICIZERS; POLYETHYLENE GLYCOLS; TECHNOLOGY, PHARMACEUTICAL; TRANSITION TEMPERATURE; X-RAY DIFFRACTION;

EID: 33748176960     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2006.05.015     Document Type: Article

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