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Volumn 100, Issue 8, 2011, Pages 3316-3331

Dissolution and precipitation behavior of amorphous solid dispersions

Author keywords

Amorphous; Crystallization inhibition; Dissolution; Felodipine; Indomethacin; Polymer; Solid dispersion; Supersaturation

Indexed keywords

FELODIPINE; HYDROXYPROPYLMETHYLCELLULOSE; INDOMETACIN; NANOPARTICLE; POLYMER; POVIDONE;

EID: 79958812380     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.22579     Document Type: Article
Times cited : (228)

References (50)
  • 1
    • 1142303337 scopus 로고    scopus 로고
    • What is the true solubility advantage for amorphous pharmaceuticals
    • Hancock BC, Parks M. 2000. What is the true solubility advantage for amorphous pharmaceuticals? Pharm Res 17(4):397-404.
    • (2000) Pharm Res , vol.17 , Issue.4 , pp. 397-404
    • Hancock, B.C.1    Parks, M.2
  • 2
    • 52949150391 scopus 로고    scopus 로고
    • Effect of polymer type on the dissolution profile of amorphous solid dispersions containing felodipine
    • Konno H, Handa T, Alonzo DE, Taylor LS. 2008. Effect of polymer type on the dissolution profile of amorphous solid dispersions containing felodipine. Eur J Pharm Biopharm 70(2):493-499.
    • (2008) Eur J Pharm Biopharm , vol.70 , Issue.2 , pp. 493-499
    • Konno, H.1    Handa, T.2    Alonzo, D.E.3    Taylor, L.S.4
  • 3
    • 0034601240 scopus 로고    scopus 로고
    • Improving drug solubility for oral delivery using solid dispersions
    • Leuner C, Dressman J. 2000. Improving drug solubility for oral delivery using solid dispersions. Eur J Pharm Biopharm 50(1):47-60.
    • (2000) Eur J Pharm Biopharm , vol.50 , Issue.1 , pp. 47-60
    • Leuner, C.1    Dressman, J.2
  • 4
    • 0014515660 scopus 로고
    • Dissolution rates of high energy polyvinylpyrrolidone (pvp)-sulfathiazole coprecipitates
    • Simonelli AP, Mehta SC, Higuchi WI. 1969. Dissolution rates of high energy polyvinylpyrrolidone (pvp)-sulfathiazole coprecipitates. J Pharm Sci 58(5):538-549.
    • (1969) J Pharm Sci , vol.58 , Issue.5 , pp. 538-549
    • Simonelli, A.P.1    Mehta, S.C.2    Higuchi, W.I.3
  • 5
    • 6944243071 scopus 로고    scopus 로고
    • Enhancing the bioavailability of ABT-963 using solid dispersion containing Pluronic F-68
    • Chen Y, Zhang GGZ, Neilly J, Marsh K, Mawhinney D, Sanzgiri YD. 2004. Enhancing the bioavailability of ABT-963 using solid dispersion containing Pluronic F-68. Int J Pharm 286(1-2):69-80.
    • (2004) Int J Pharm , vol.286 , Issue.1-2 , pp. 69-80
    • Chen, Y.1    Zhang, G.G.Z.2    Neilly, J.3    Marsh, K.4    Mawhinney, D.5    Sanzgiri, Y.D.6
  • 6
    • 64649088132 scopus 로고    scopus 로고
    • Amorphous cmpositions using concentration enhancing polymers for improved bioavailability of itraconazole
    • DiNunzio JC, Miller DA, Yang W, McGinity JW, Williams RO. 2008. Amorphous cmpositions using concentration enhancing polymers for improved bioavailability of itraconazole. Mol Pharm 5(6):968-980.
    • (2008) Mol Pharm , vol.5 , Issue.6 , pp. 968-980
    • DiNunzio, J.C.1    Miller, D.A.2    Yang, W.3    McGinity, J.W.4    Williams, R.O.5
  • 9
    • 33745590868 scopus 로고    scopus 로고
    • Supersaturation produces high bioavailability of amorphous danazol particles formed by evaporative precipitation into aqueous solution and spray freezing into liquid technologies
    • Vaughn JM, McConville JT, Crisp MT, Johnston KP, Williams RO. 2006. Supersaturation produces high bioavailability of amorphous danazol particles formed by evaporative precipitation into aqueous solution and spray freezing into liquid technologies. Drug Dev Ind Pharm 32(5):559-567.
    • (2006) Drug Dev Ind Pharm , vol.32 , Issue.5 , pp. 559-567
    • Vaughn, J.M.1    McConville, J.T.2    Crisp, M.T.3    Johnston, K.P.4    Williams, R.O.5
  • 10
    • 77953171784 scopus 로고    scopus 로고
    • Understanding the behavior of amorphous pharmaceutical systems during dissolution
    • Alonzo DE, Zhang GGZ, Zhou DL, Gao Y, Taylor LS. 2010. Understanding the behavior of amorphous pharmaceutical systems during dissolution. Pharm Res 27(4):608-618.
    • (2010) Pharm Res , vol.27 , Issue.4 , pp. 608-618
    • Alonzo, D.E.1    Zhang, G.G.Z.2    Zhou, D.L.3    Gao, Y.4    Taylor, L.S.5
  • 11
    • 76649105411 scopus 로고    scopus 로고
    • Solubility advantage of amorphous pharmaceuticals: I. A Thermodynamic analysis
    • Murdande SB, Pikal MJ, Shanker RM, Bogner RH. 2009. Solubility advantage of amorphous pharmaceuticals: I. A Thermodynamic analysis. J Pharm Sci 99(3):1254-1264.
    • (2009) J Pharm Sci , vol.99 , Issue.3 , pp. 1254-1264
    • Murdande, S.B.1    Pikal, M.J.2    Shanker, R.M.3    Bogner, R.H.4
  • 12
    • 78651304897 scopus 로고    scopus 로고
    • Aqueous solubility of crystalline and amorphous drugs: Challenges in measurement
    • Murdande SB, Pikal MJ, Shanker R, Bogner RH. 2011. Aqueous solubility of crystalline and amorphous drugs: Challenges in measurement. Pharm Dev Technol. 16(3):187-200.
    • (2011) Pharm Dev Technol. , vol.16 , Issue.3 , pp. 187-200
    • Murdande, S.B.1    Pikal, M.J.2    Shanker, R.3    Bogner, R.H.4
  • 13
    • 36849125484 scopus 로고
    • Thermodynamic driving force in nucleation and growth processes
    • Hoffman JD. 1958. Thermodynamic driving force in nucleation and growth processes. J Chem Phys 29(5):1192-1193.
    • (1958) J Chem Phys , vol.29 , Issue.5 , pp. 1192-1193
    • Hoffman, J.D.1
  • 14
    • 33749447574 scopus 로고    scopus 로고
    • A comparison of the physical stability of amorphous felodipine and nifedipine systems
    • Marsac PJ, Konno H, Taylor LS. 2006. A comparison of the physical stability of amorphous felodipine and nifedipine systems. Pharm Res 23(10):2306-2316.
    • (2006) Pharm Res , vol.23 , Issue.10 , pp. 2306-2316
    • Marsac, P.J.1    Konno, H.2    Taylor, L.S.3
  • 15
    • 58149151056 scopus 로고    scopus 로고
    • Highly supersaturated solutions of amorphous drugs approaching predictions from configurational thermodynamic properties
    • Matteucci ME, Miller MA, Williams RO, Johnston KP. 2008. Highly supersaturated solutions of amorphous drugs approaching predictions from configurational thermodynamic properties. J Phys Chem B 112(51):16675-16681.
    • (2008) J Phys Chem B , vol.112 , Issue.51 , pp. 16675-16681
    • Matteucci, M.E.1    Miller, M.A.2    Williams, R.O.3    Johnston, K.P.4
  • 16
    • 12244283119 scopus 로고    scopus 로고
    • Characterization of solid dispersions of itraconazole and hydroxypropylmethylcellulose prepared by melt extrusion-Part I
    • Verreck G, Six K, Van den Mooter G, Baert L, Peeters J, Brewster ME. 2003. Characterization of solid dispersions of itraconazole and hydroxypropylmethylcellulose prepared by melt extrusion-Part I. Int J Pharm 251(1-2):165-174.
    • (2003) Int J Pharm , vol.251 , Issue.1-2 , pp. 165-174
    • Verreck, G.1    Six, K.2    Van den, M.G.3    Baert, L.4    Peeters, J.5    Brewster, M.E.6
  • 17
    • 0037074108 scopus 로고    scopus 로고
    • The mechanisms of drug release from solid dispersions in water-soluble polymers
    • Craig DQM. 2002. The mechanisms of drug release from solid dispersions in water-soluble polymers. Int J Pharm 231(2):131-144.
    • (2002) Int J Pharm , vol.231 , Issue.2 , pp. 131-144
    • Craig, D.Q.M.1
  • 18
    • 0032885450 scopus 로고    scopus 로고
    • Solid dispersion of poorly water-soluble drugs: Early promises, subsequent problems, and recent breakthroughs
    • Serajuddin ATM. 1999. Solid dispersion of poorly water-soluble drugs: Early promises, subsequent problems, and recent breakthroughs. J Pharm Sci 88(10):1058-1066.
    • (1999) J Pharm Sci , vol.88 , Issue.10 , pp. 1058-1066
    • Serajuddin, A.T.M.1
  • 19
    • 6344247455 scopus 로고    scopus 로고
    • Stability and solubility of celecoxib-PVP amorphous dispersions: A molecular perspective
    • Gupta P, Kakumanu VK, Bansal AK. 2004. Stability and solubility of celecoxib-PVP amorphous dispersions: A molecular perspective. Pharm Res 21(10):1762-1769.
    • (2004) Pharm Res , vol.21 , Issue.10 , pp. 1762-1769
    • Gupta, P.1    Kakumanu, V.K.2    Bansal, A.K.3
  • 20
    • 39049128727 scopus 로고    scopus 로고
    • Preparation, characterization, and dissolution behavior of a solid dispersion of Simvastatin with polyethylene glycol 4000 and polyvinylpyrrolidone K30
    • Patel R, Patel M. 2008. Preparation, characterization, and dissolution behavior of a solid dispersion of Simvastatin with polyethylene glycol 4000 and polyvinylpyrrolidone K30. J Dispersion Sci Technol 29:193-204.
    • (2008) J Dispersion Sci Technol , vol.29 , pp. 193-204
    • Patel, R.1    Patel, M.2
  • 21
    • 33846256269 scopus 로고    scopus 로고
    • Influence of different polymers on the crystallization tendency of molecularly dispersed amorphous felodipine
    • Konno H, Taylor LS. 2006. Influence of different polymers on the crystallization tendency of molecularly dispersed amorphous felodipine. J Pharm Sci 95(12):2692-2705.
    • (2006) J Pharm Sci , vol.95 , Issue.12 , pp. 2692-2705
    • Konno, H.1    Taylor, L.S.2
  • 22
    • 0029056118 scopus 로고
    • Inhibition of indomethacin crystallization in poly(vinylpyrrolidone) coprecipitates
    • Yoshioka M, Hancock BC, Zografi G. 1995. Inhibition of indomethacin crystallization in poly(vinylpyrrolidone) coprecipitates. J Pharm Sci 84(8):983-986.
    • (1995) J Pharm Sci , vol.84 , Issue.8 , pp. 983-986
    • Yoshioka, M.1    Hancock, B.C.2    Zografi, G.3
  • 23
    • 0031423468 scopus 로고    scopus 로고
    • Spectroscopic characterization of interactions between PVP and indomethacin in amorphous molecular dispersions
    • Taylor LS, Zografi G. 1997. Spectroscopic characterization of interactions between PVP and indomethacin in amorphous molecular dispersions. Pharm Res 14(12):1691-1698.
    • (1997) Pharm Res , vol.14 , Issue.12 , pp. 1691-1698
    • Taylor, L.S.1    Zografi, G.2
  • 24
    • 0028972331 scopus 로고
    • The solution-diffusion model-A review
    • Wijmans JG, Baker RW. 1995. The solution-diffusion model-A review. J Membrane Sci 107(1-2):1-21.
    • (1995) J Membrane Sci , vol.107 , Issue.1-2 , pp. 1-21
    • Wijmans, J.G.1    Baker, R.W.2
  • 25
    • 77954215037 scopus 로고    scopus 로고
    • Quantitative NMR spectroscopy in pharmaceutical applications
    • Holzgrabe U. 2010. Quantitative NMR spectroscopy in pharmaceutical applications. Prog Nucl Magn Reson Spectrosc 57(2):229-240.
    • (2010) Prog Nucl Magn Reson Spectrosc , vol.57 , Issue.2 , pp. 229-240
    • Holzgrabe, U.1
  • 26
    • 0019221048 scopus 로고
    • Drug membrane-transport enhancement using high-energy drug polyvinylpyrrolidone (pvp) co-precipitates
    • Corrigan OI, Farvar MA, Higuchi WI. 1980. Drug membrane-transport enhancement using high-energy drug polyvinylpyrrolidone (pvp) co-precipitates. Int J Pharm 5(3):229-238.
    • (1980) Int J Pharm , vol.5 , Issue.3 , pp. 229-238
    • Corrigan, O.I.1    Farvar, M.A.2    Higuchi, W.I.3
  • 27
    • 0024266630 scopus 로고
    • Supersaturation mechanism of drugs from solid dispersions with enteric coating agents
    • Hasegawa A, Taguchi M, Suzuki R, Miyata T, Nakagawa H, Sugimoto I. 1988. Supersaturation mechanism of drugs from solid dispersions with enteric coating agents. Chem Pharm Bull 36(12):4941-4950.
    • (1988) Chem Pharm Bull , vol.36 , Issue.12 , pp. 4941-4950
    • Hasegawa, A.1    Taguchi, M.2    Suzuki, R.3    Miyata, T.4    Nakagawa, H.5    Sugimoto, I.6
  • 28
    • 0023133692 scopus 로고
    • Mechanisms of dissolution of frusemide PVP solid dispersions
    • Doherty C, York P. 1987. Mechanisms of dissolution of frusemide PVP solid dispersions. Int J Pharm 34(3):197-205.
    • (1987) Int J Pharm , vol.34 , Issue.3 , pp. 197-205
    • Doherty, C.1    York, P.2
  • 29
    • 0017235421 scopus 로고
    • Dissolution rates of high-energy sulfathiazole-povidone coprecipitates.2. Characterization of form of drug controlling its dissolution rate via solubility studies
    • Simonelli AP, Mehta SC, Higuchi WI. 1976. Dissolution rates of high-energy sulfathiazole-povidone coprecipitates.2. Characterization of form of drug controlling its dissolution rate via solubility studies. J Pharm Sci 65(3):355-361.
    • (1976) J Pharm Sci , vol.65 , Issue.3 , pp. 355-361
    • Simonelli, A.P.1    Mehta, S.C.2    Higuchi, W.I.3
  • 31
    • 77954678690 scopus 로고    scopus 로고
    • Technical evaluation of a fiber-optic probe dissolution system
    • Liu L, Fitzgerald G, Embry M, Cantu R, Pack B. 2008. Technical evaluation of a fiber-optic probe dissolution system. Dissolution Technol 15(1):10-20.
    • (2008) Dissolution Technol , vol.15 , Issue.1 , pp. 10-20
    • Liu, L.1    Fitzgerald, G.2    Embry, M.3    Cantu, R.4    Pack, B.5
  • 32
    • 62849083839 scopus 로고    scopus 로고
    • Comprehensive validation scheme for in situ fiber optics dissolution method for pharmaceutical drug product testing
    • Mirza T, Liu Q, Vivilecchia R, Joshi Y. 2009. Comprehensive validation scheme for in situ fiber optics dissolution method for pharmaceutical drug product testing. J Pharm Sci 98(3):1086-1094.
    • (2009) J Pharm Sci , vol.98 , Issue.3 , pp. 1086-1094
    • Mirza, T.1    Liu, Q.2    Vivilecchia, R.3    Joshi, Y.4
  • 35
    • 79959887126 scopus 로고    scopus 로고
    • Influence of particle size on the ultraviolet spectrum of particulate-containing solutions-Implications for in-situ concentration monitoring using UV/Vis fiber-optic probes
    • DOI: 10.1007/s11095-011-0399-4.
    • van Eerdenbrugh B, Alonzo DE, Taylor LS. 2011. Influence of particle size on the ultraviolet spectrum of particulate-containing solutions-Implications for in-situ concentration monitoring using UV/Vis fiber-optic probes. Pharm Res. DOI: 10.1007/s11095-011-0399-4.
    • (2011) Pharm Res.
    • van Eerdenbrugh, B.1    Alonzo, D.E.2    Taylor, L.S.3
  • 37
    • 0021873176 scopus 로고
    • Mechanisms of dissolution of fast release solid dispersions
    • Corrigan OI. 1985. Mechanisms of dissolution of fast release solid dispersions. Drug Dev Ind Pharm 11(2-3):697-724.
    • (1985) Drug Dev Ind Pharm , vol.11 , Issue.2-3 , pp. 697-724
    • Corrigan, O.I.1
  • 38
    • 0023039336 scopus 로고
    • Retardation of polymeric carrier dissolution by dispersed drugs-Factors influencing the dissolution of solid dispersions containing polyethylene glycols
    • Corrigan OI. 1986. Retardation of polymeric carrier dissolution by dispersed drugs-Factors influencing the dissolution of solid dispersions containing polyethylene glycols. Drug Dev Ind Pharm 12(11-13):1777-1793.
    • (1986) Drug Dev Ind Pharm , vol.12 , Issue.11-13 , pp. 1777-1793
    • Corrigan, O.I.1
  • 39
    • 0019967104 scopus 로고
    • Mechanism of drug dissolution rate enhancement from beta-cyclodextrin-drug systems
    • Corrigan OI, Stanley CT. 1982. Mechanism of drug dissolution rate enhancement from beta-cyclodextrin-drug systems. J Pharm Pharmacol 34(10):621-626.
    • (1982) J Pharm Pharmacol , vol.34 , Issue.10 , pp. 621-626
    • Corrigan, O.I.1    Stanley, C.T.2
  • 40
    • 0018732493 scopus 로고
    • Approximation of the free-energy change on crystallization
    • Thompson CV, Spaepen F. 1979. Approximation of the free-energy change on crystallization. Acta Metallurgica 27(12):1855-1859.
    • (1979) Acta Metallurgica , vol.27 , Issue.12 , pp. 1855-1859
    • Thompson, C.V.1    Spaepen, F.2
  • 41
    • 57749206650 scopus 로고    scopus 로고
    • Estimation of drug-polymer miscibility and solubility in amorphous solid dispersions using experimentally determined interaction parameters
    • Marsac P, Li T, Taylor L. 2009. Estimation of drug-polymer miscibility and solubility in amorphous solid dispersions using experimentally determined interaction parameters. Pharm Res 26(1):139-151.
    • (2009) Pharm Res , vol.26 , Issue.1 , pp. 139-151
    • Marsac, P.1    Li, T.2    Taylor, L.3
  • 42
    • 61449135800 scopus 로고    scopus 로고
    • Solubility of small-molecule crystals in polymers: d-Mannitol in PVP, indomethacin in PVP/VA, and nifedipine in PVP/VA
    • Tao J, Sun Y, Zhang GGZ, Yu L. 2009. Solubility of small-molecule crystals in polymers: d-Mannitol in PVP, indomethacin in PVP/VA, and nifedipine in PVP/VA. Pharm Res 26(4):855-864.
    • (2009) Pharm Res , vol.26 , Issue.4 , pp. 855-864
    • Tao, J.1    Sun, Y.2    Zhang, G.G.Z.3    Yu, L.4
  • 43
    • 33749442356 scopus 로고    scopus 로고
    • Theoretical and practical approaches for prediction of drug-polymer miscibility and solubility
    • Marsac PJ, Shamblin SL, Taylor LS. 2006. Theoretical and practical approaches for prediction of drug-polymer miscibility and solubility. Pharm Res 23(10):2417-2426.
    • (2006) Pharm Res , vol.23 , Issue.10 , pp. 2417-2426
    • Marsac, P.J.1    Shamblin, S.L.2    Taylor, L.S.3
  • 44
    • 56049087064 scopus 로고    scopus 로고
    • Determination of the activity of a molecular solute in saturated solution
    • Nordstrom FL, Rasmuson AC. 2008. Determination of the activity of a molecular solute in saturated solution. J Chem Thermodyn 40(12):1684-1692.
    • (2008) J Chem Thermodyn , vol.40 , Issue.12 , pp. 1684-1692
    • Nordstrom, F.L.1    Rasmuson, A.C.2
  • 45
  • 47
    • 0034820643 scopus 로고    scopus 로고
    • Water vapor absorption into amorphous sucrose-poly(vinyl pyrrolidone) and trehalose-poly(vinyl pyrrolidone) mixtures
    • Zhang J, Zografi G. 2001. Water vapor absorption into amorphous sucrose-poly(vinyl pyrrolidone) and trehalose-poly(vinyl pyrrolidone) mixtures. J Pharm Sci 90(9):1375-1385.
    • (2001) J Pharm Sci , vol.90 , Issue.9 , pp. 1375-1385
    • Zhang, J.1    Zografi, G.2
  • 48
    • 12844279900 scopus 로고    scopus 로고
    • Influence of the chain composition on the thermodynamic properties of binary and ternary polymer solutions
    • Csaki KF, Nagy M, Csempesz F. 2005. Influence of the chain composition on the thermodynamic properties of binary and ternary polymer solutions. Langmuir 21(2):761-766.
    • (2005) Langmuir , vol.21 , Issue.2 , pp. 761-766
    • Csaki, K.F.1    Nagy, M.2    Csempesz, F.3
  • 49
    • 33745179548 scopus 로고    scopus 로고
    • Compatibility of polymer blends. I. Copolymers with organic solvents
    • Sabzi F, Boushehri A. 2006. Compatibility of polymer blends. I. Copolymers with organic solvents. J Appl Polym Sci 101(1):492-498.
    • (2006) J Appl Polym Sci , vol.101 , Issue.1 , pp. 492-498
    • Sabzi, F.1    Boushehri, A.2
  • 50
    • 77951222639 scopus 로고    scopus 로고
    • Analysis of the moisture sorption behavior of amorphous drug-polymer blends
    • Rumondor ACF, Konno H, Marsac PJ, Taylor LS. Analysis of the moisture sorption behavior of amorphous drug-polymer blends. J Appl Polym Sci 117(2):1055-1063.
    • J Appl Polym Sci , vol.117 , Issue.2 , pp. 1055-1063
    • Rumondor, A.C.F.1    Konno, H.2    Marsac, P.J.3    Taylor, L.S.4


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