Influence of compression on water sorption, glass transition, and enthalpy relaxation behavior of freeze-dried amorphous sugar matrices

International Journal of Pharmaceutics

Volumn 408, Issue 1-2, 2011, Pages 76-83

  Imamura, Koreyoshi ^a   Kagotani, Ryo ^a   Nomura, Mayo ^a   Tanaka, Kazuhiro ^a   Kinugawa, Kohshi ^a   Nakanishi, Kazuhiro ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

Amorphous sugar; Compression; Freeze drying; Glass transition temperature; Structural relaxation; Water sorption

Indexed keywords

ALPHA LACTOSE; ALPHA MALTOSE; GLASS; MALTOSE; SUCROSE; SUGAR; TREHALOSE; UNCLASSIFIED DRUG; WATER;

ARTICLE; COMPRESSION; ENTHALPY; PRIORITY JOURNAL; WATER CONTENT; WATER VAPOR;

ADSORPTION; CARBOHYDRATES; DRUG STABILITY; EXCIPIENTS; FREEZE DRYING; PHASE TRANSITION; POROSITY; TECHNOLOGY, PHARMACEUTICAL; THERMODYNAMICS; WATER;

EID: 79953234011     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.01.052     Document Type: Article

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