Preparation of microspheres containing low solubility drug compound by electrohydrodynamic spraying

International Journal of Pharmaceutics

Volumn 412, Issue 1-2, 2011, Pages 59-67

  Bohr, Adam ^a,b   Kristensen, Jakob ^b   Stride, Eleanor ^a   Dyas, Mark ^b   Edirisinghe, Mohan ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b LifeCycle Pharma   (Denmark)

Author keywords

Celecoxib; Electrospraying; Low solubility; Microsphere; Particle engineering; PLGA

Indexed keywords

CELECOXIB; MICROSPHERE; POLYGLACTIN;

ARTICLE; DISSOLUTION; DRUG BIOAVAILABILITY; DRUG SOLUBILITY; ELECTROSPRAY; HYDRODYNAMICS; PRIORITY JOURNAL; SURFACE PROPERTY; SUSTAINED DRUG RELEASE;

CALORIMETRY, DIFFERENTIAL SCANNING; CYCLOOXYGENASE 2 INHIBITORS; DIFFUSION; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; ELECTROCHEMICAL TECHNIQUES; HYDRODYNAMICS; LACTIC ACID; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; PARTICLE SIZE; POLYGLYCOLIC ACID; POROSITY; PYRAZOLES; SOLUBILITY; SULFONAMIDES; SURFACE PROPERTIES; TEMPERATURE; TRANSITION TEMPERATURE;

EID: 79957494278     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.04.005     Document Type: Article

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